LOCUS AF013759 3316 bp mRNA linear HUM 27-MAY-1998
DEFINITION Homo sapiens calumein (Calu) mRNA, complete cds.
ACCESSION AF013759
VERSION AF013759.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3316)
AUTHORS Yabe,D., Taniwaki,M., Nakamura,T., Kanazawa,N., Tashiro,K. and
Honjo,T.
TITLE Human calumenin gene (CALU): cDNA isolation and chromosomal mapping
to 7q32
JOURNAL Genomics 49 (2), 331-333 (1998)
PUBMED 9598325
REFERENCE 2 (bases 1 to 3316)
AUTHORS Yabe,D., Taniwaki,M., Nakamura,T., Kanazawa,N., Tashiro,K. and
Honjo,T.
TITLE Direct Submission
JOURNAL Submitted (13-JUL-1997) Department of Medical Chemistry, Kyoto
University Faculty of Medicine, Yoshida Konoe-cho, Sakyo-ku, Kyoto
606, Japan
FEATURES Location/Qualifiers
source 1..3316
/db_xref="H-InvDB:HIT000062275"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q32"
source 1..2415
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/note="derived from EST clone 645121"
gene 1..3316
/gene="Calu"
CDS 59..1006
/gene="Calu"
/function="Ca2+-binding in the ER"
/note="member of one subset of EF-hand superfamily that
includes reticulocalbin, Erc-55, and Cab-45"
/codon_start=1
/product="calumein"
/protein_id="AAC17216.1"
/translation="MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQS
FDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQK
RWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRF
KMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMY
SHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYE
SDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF"
sig_peptide 59..115
/gene="Calu"
misc_feature 299..334
/gene="Calu"
/note="Region: EF-hand motif I"
misc_feature 407..442
/gene="Calu"
/note="Region: EF-hand motif II"
misc_feature 521..550
/gene="Calu"
/note="Region: EF-hand motif III"
misc_feature 656..694
/gene="Calu"
/note="Region: EF-hand motif IV"
misc_feature 782..817
/gene="Calu"
/note="Region: EF-hand motif V"
misc_feature 860..925
/gene="Calu"
/note="Region: EF-hand motif VI"
misc_feature 922..1003
/gene="Calu"
/note="encodes C-terminal ER retention signal"
BASE COUNT 969 a 656 c 718 g 973 t
ORIGIN
1 gtgagcggcg gccacggcat cctgtgctgt gggggctacg aggaaagatc taattatcat
61 ggacctgcga cagtttctta tgtgcctgtc cctgtgcaca gcctttgcct tgagcaaacc
121 cacagaaaag aaggaccgtg tacatcatga gcctcagctc agtgacaagg ttcacaatga
181 tgctcagagt tttgattatg accatgatgc cttcttgggt gctgaagaag caaagacctt
241 tgatcagctg acaccagaag agagcaagga aaggcttgga aagattgtaa gtaaaataga
301 tggcgacaag gacgggtttg tcactgtgga tgagctcaaa gactggatta aatttgcaca
361 aaagcgctgg atttacgagg atgtagagcg acagtggaag gggcatgacc tcaatgagga
421 cggcctcgtt tcctgggagg agtataaaaa tgccacctac ggctacgttt tagatgatcc
481 agatcctgat gatggattta actataaaca gatgatggtt agagatgagc ggaggtttaa
541 aatggcagac aaggatggag acctcattgc caccaaggag gagttcacag ctttcctgca
601 ccctgaggag tatgactaca tgaaagatat agtagtacag gaaacaatgg aagatataga
661 taagaatgct gatggtttca ttgatctaga agagtatatt ggtgacatgt acagccatga
721 tgggaatact gatgagccag aatgggtaaa gacagagcga gagcagtttg ttgagtttcg
781 ggataagaac cgtgatggga agatggacaa ggaagagacc aaagactgga tccttccctc
841 agactatgat catgcagagg cagaagccag gcacctggtc tatgaatcag accaaaacaa
901 ggatggcaag cttaccaagg aggagatcgt tgacaagtat gacttatttg ttggcagcca
961 ggccacagat tttggggagg ccttagtacg gcatgatgag ttctgagctg cggaggaacc
1021 ctcatttcct caaaagtaat ttatttttac agcttctggt ttcacatgaa attgtttgcg
1081 ctactgagac tgttactaca aactttttaa gacatgaaaa ggcgtaatga aaaccatccc
1141 gtccccattc ctcctcctct ctgagggact ggagggaagc cgtgcttctg aggaacaact
1201 ctaattagta cacttgtgtt tgtagattta cactttgtat tatgtattaa catggcgtgt
1261 ttatttttgt atttttctct ggttgggagt atgatatgaa ggatcaagat cctccactca
1321 cacatgtaga caaacattag ctctttactc tttctcaacc ccttatatga ttttaataat
1381 tctcacttca ctaattttgt aagcctgaga tcaataagaa atgttcagga gagaggaaag
1441 aaaaaatata tatgctccac aatttatatt tagagagaga acacttagtc ttgcctgtca
1501 aaaagtccaa catttcatag gtagtagggg ccacatatta cattcagttg ctataggtcc
1561 agcaactgaa cctgccatta cctgggcaag gaaagatccc tttgctctag gaaagcttgg
1621 cccaaattga ttttcttctt tttccccctg taggactgac tgttggctaa ttttgtcaag
1681 cacagctgtg gtgggaagag ttagggccag tgtcttgaaa atcaatcaag tagtgaatgt
1741 gatctctttg cagagctata gatagaaaca gctggaaaac taaaggaaaa atacaaatgt
1801 tttcggggca tacatttttt ttctgggtgt gcatctgttg aaatgctcaa gacttaatta
1861 tttgcctttt gaaatcactg taaatgcccc catccggttc ctcttcttcc caggtgtgcc
1921 aaggaattaa tcttggtttc actacaatta aaattcactc ctttccaatc atgtcattga
1981 aagtgccttt aacgaaagaa atggtcactg aatgggaatt ctcttaagaa accctgagat
2041 taaaaaaaga ctatttggat aacttatagg aaagcctaga acctcccagt agagtgggga
2101 tttttttctt cttccctttc tcttttggac aatagttaaa ttagcagtat tagttatgag
2161 tttggttgca gtgttcttat cttgtgggct gatttccaaa aaccacatgc tgctgaattt
2221 accagggatc ctcatacctc acaatgcaaa ccacttacta ccaggccttt ttctgtgtcc
2281 actggagagc ttgagctcac actcaaagat cagaggacct acagagaggg ctctttggtt
2341 tgaggaccat ggcttacctt tcctgccttt gacccatcac accccatttc ctcctctttc
2401 cctctccccg ctgccaaaaa aaaaaaaaag gaaacgttta tcatgaatca acagggtttc
2461 agtccttatc aaagagagat gtggaaagag ctaaagaaac caccctttgt tcccaactcc
2521 actttaccca tattttatgc aacacaaaca ctgtcctttt gggtcccttt cttacagatg
2581 gacctcttga gaagaattat cgtattccac gtttttagcc ctcaggttac caagataaat
2641 atatgtatat ataaccttta ttattgctat atctttgtgg ataatacatt caggtggtgc
2701 tgggtgattt attataatct gaacctaggt atatcctttg gtcttccaca gtcatgttga
2761 ggtgggctcc ctggtatggt aaaaagccag gtataatgta acttcacccc agcctttgta
2821 ctaagctctt gatagtggat atactctttt aagtttagcc ccaatatagg gtaatggaaa
2881 tttcctgccc tctgggttcc ccatttttac tattaagaag accagtgata atttaataat
2941 gccaccaact ctggcttagt taagtgagag tgtgaactgt gtggcaagag agcctcacac
3001 ctcactaggt gcagagagcc caggccttat gttaaaatca tgcacttgaa aagcaaacct
3061 taatctgcaa agacagcagc aagcattata cggtcatctt gaatgatccc tttgaaattt
3121 tttttttgtt tgtttgttta aatcaagcct gaggctggtg aacagtagct acacacccat
3181 attgtgtgtt ctgtgaatgc tagctctctt gaatttggat attggttatt ttttatagag
3241 tgtaaaccaa gttttatatt ctgcaatgcg aacaggtacc tatctgtttc taaataaaac
3301 tgtttacatt caaaaa
//