LOCUS AF012890 2238 bp mRNA linear HUM 09-AUG-1997
DEFINITION Homo sapiens IKK-a kinase (IKK-a) mRNA, complete cds.
ACCESSION AF012890
VERSION AF012890.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2238)
AUTHORS Regnier,C.H., Song,H.Y., Gao,X., Goeddel,D.V., Cao,Z. and Rothe,M.
TITLE Identification and characterization of an IkappaB kinase
JOURNAL Cell 90 (2), 373-383 (1997)
PUBMED 9244310
REFERENCE 2 (bases 1 to 2238)
AUTHORS Regnier,C.H., Song,H.Y., Gao,X., Goeddel,D.V., Cao,Z. and Rothe,M.
TITLE Direct Submission
JOURNAL Submitted (07-JUL-1997) Tularik, Inc., Two Corporate Dr., S. San
Francisco, CA 94080, USA
FEATURES Location/Qualifiers
source 1..2238
/db_xref="H-InvDB:HIT000062249"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2238
/gene="IKK-a"
CDS 1..2238
/gene="IKK-a"
/codon_start=1
/product="IKK-a kinase"
/protein_id="AAC51662.1"
/translation="MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIK
SCRLELSTKNRERWCHEIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGD
LRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKII
HKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGY
RPFLHHLQPFTWHEKIKKKDPKCIFACEEMSGEVRFSSHLPQPNSLCSLIVEPMENWL
QLMLNWDPQQRGGPVDLTLKQPRCFVLMDHILNLKIVHILNMTSAKIISFLLPPDESL
HSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKT
VYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRA
AMLSLLRYNANLTKMKNTLISASQQLKAKLEFFHKSIQLDLERYSEQMTYGISSEKML
KAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAEIMELQKSPYGRRQGDLMESLEQRAID
LYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPK
VEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGAVTPQTSAW
LPPTSAEHDHSLSCVVTPQDGETSAQMIEENLNCLGHLSTIIHEANEEQGNSMMNLDW
SWLTE"
BASE COUNT 689 a 408 c 535 g 606 t
ORIGIN
1 atggagcggc ccccggggct gcggccgggc gcgggcgggc cctgggagat gcgggagcgg
61 ctgggcaccg gcggcttcgg gaacgtctgt ctgtaccagc atcgggaact tgatctcaaa
121 atagcaatta agtcttgtcg cctagagcta agtaccaaaa acagagaacg atggtgccat
181 gaaatccaga ttatgaagaa gttgaaccat gccaatgttg taaaggcctg tgatgttcct
241 gaagaattga atattttgat tcatgatgtg cctcttctag caatggaata ctgttctgga
301 ggagatctcc gaaagctgct caacaaacca gaaaattgtt gtggacttaa agaaagccag
361 atactttctt tactaagtga tatagggtct gggattcgat atttgcatga aaacaaaatt
421 atacatcgag atctaaaacc tgaaaacata gttcttcagg atgttggtgg aaagataata
481 cataaaataa ttgatctggg atatgccaaa gatgttgatc aaggaagtct gtgtacatct
541 tttgtgggaa cactgcagta tctggcccca gagctctttg agaataagcc ttacacagcc
601 actgttgatt attggagctt tgggaccatg gtatttgaat gtattgctgg atataggcct
661 tttttgcatc atctgcagcc atttacctgg catgagaaga ttaagaagaa ggatccaaag
721 tgtatatttg catgtgaaga gatgtcagga gaagttcggt ttagtagcca tttacctcaa
781 ccaaatagcc tttgtagttt aatagtagaa cccatggaaa actggctaca gttgatgttg
841 aattgggacc ctcagcagag aggaggacct gttgacctta ctttgaagca gccaagatgt
901 tttgtattaa tggatcacat tttgaatttg aagatagtac acatcctaaa tatgacttct
961 gcaaagataa tttcttttct gttaccacct gatgaaagtc ttcattcact acagtctcgt
1021 attgagcgtg aaactggaat aaatactggt tctcaagaac ttctttcaga gacaggaatt
1081 tctctggatc ctcggaaacc agcctctcaa tgtgttctag atggagttag aggctgtgat
1141 agctatatgg tttatttgtt tgataaaagt aaaactgtat atgaagggcc atttgcttcc
1201 agaagtttat ctgattgtgt aaattatatt gtacaggaca gcaaaataca gcttccaatt
1261 atacagctgc gtaaagtgtg ggctgaagca gtgcactatg tgtctggact aaaagaagac
1321 tatagcaggc tctttcaggg acaaagggca gcaatgttaa gtcttcttag atataatgct
1381 aacttaacaa aaatgaagaa cactttgatc tcagcatcac aacaactgaa agctaaattg
1441 gagttttttc acaaaagcat tcagcttgac ttggagagat acagcgagca gatgacgtat
1501 gggatatctt cagaaaaaat gctaaaagca tggaaagaaa tggaagaaaa ggccatccac
1561 tatgctgagg ttggtgtcat tggatacctg gaggatcaga ttatgtcttt gcatgctgaa
1621 atcatggagc tacagaagag cccctatgga agacgtcagg gagacttgat ggaatctctg
1681 gaacagcgtg ccattgatct atataagcag ttaaaacaca gaccttcaga tcactcctac
1741 agtgacagca cagagatggt gaaaatcatt gtgcacactg tgcagagtca ggaccgtgtg
1801 ctcaaggagc tgtttggtca tttgagcaag ttgttgggct gtaagcagaa gattattgat
1861 ctactcccta aggtggaagt ggccctcagt aatatcaaag aagctgacaa tactgtcatg
1921 ttcatgcagg gaaaaaggca gaaagaaata tggcatctcc ttaaaattgc ctgtacacag
1981 agttctgccc ggtcccttgt aggatccagt ctagaaggtg cagtaacccc tcagacatca
2041 gcatggctgc ccccgacttc agcagaacat gatcattctc tgtcatgtgt ggtaactcct
2101 caagatgggg agacttcagc acaaatgata gaagaaaatt tgaactgcct tggccattta
2161 agcactatta ttcatgaggc aaatgaggaa cagggcaata gtatgatgaa tcttgattgg
2221 agttggttaa cagaatga
//