LOCUS AF012074 2984 bp mRNA linear HUM 03-FEB-1998
DEFINITION Homo sapiens cAMP-specific phosphodiesterase PDE4D2 (PDE4D) mRNA,
complete cds.
ACCESSION AF012074
VERSION AF012074.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2984)
AUTHORS Bolger,G.B., Erdogan,S., Jones,R.E., Loughney,K., Scotland,G.,
Hoffmann,R., Wilkinson,I., Farrell,C. and Houslay,M.D.
TITLE Characterization of five different proteins produced by
alternatively spliced mRNAs from the human cAMP-specific
phosphodiesterase PDE4D gene
JOURNAL Biochem. J. 328 (Pt 2), 539-548 (1997)
PUBMED 9371713
REFERENCE 2 (bases 1 to 2984)
AUTHORS Bolger,G.B., Erdogan,S., Jones,R.E., Loughney,K., Scotland,G.,
Hoffman,R., Wilkinson,I., Farrell,C. and Houslay,M.D.
TITLE Direct Submission
JOURNAL Submitted (01-JUL-1997) Medicine (Heme/Onc), University of Utah,
Room 4C416, S.O.M., Salt Lake City, UT 84132, USA
FEATURES Location/Qualifiers
source 1..2984
/db_xref="H-InvDB:HIT000062228"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q13"
/clone="S3"
/cell_line="HeLa"
gene 1..2984
/gene="PDE4D"
CDS 568..2091
/gene="PDE4D"
/codon_start=1
/product="cAMP-specific phosphodiesterase PDE4D2"
/protein_id="AAC00070.1"
/translation="MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEI
PSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKW
GLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYH
NNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSE
LALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKH
MNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTD
RIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDA
QDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDS
GSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT"
BASE COUNT 840 a 668 c 697 g 779 t
ORIGIN
1 gaattcggca cgaggtggtg gccgcgcacc cggccgcggc tgattcattc acttcaagtg
61 ccgtgcagaa ggctcggcag gcggggcggg cgtggggccg cggctccggg ttggggaccg
121 aggagatccg gctgtggacc agacgctcct ctgcggggcg ggcacccaag cgcgctcgcc
181 accccctcgc catccgctag agccgggctc ctggactggg actcgggccc gccgcacagt
241 tgaaaagtcg catagtggtt tttccgctcg cgtcgctgtg tgaaagttgg ctcgccgctc
301 tttgcacgcc ctccctggag gccgacccga gacgccaagc tggagagacc gtgcctcccc
361 gaggccggcc gccccgcgag cacagcctcc gcccccgttg cactgccggg ctgggcaata
421 tgaaggagca gccctcatgt gccggcaccg ggcatccgag catggcggga ggaggcctac
481 cagaaactgg ccagcgagac cctggaggag ctggactggt gtctggacca gctagagacc
541 ctacagacca ggcactccgt cagtgagatg gcctccaaca agtttaaaag gatgcttaat
601 cgggagctca cccatctctc tgaaatgagt cggtctggaa atcaagtgtc agagtttata
661 tcaaacacat tcttagataa gcaacatgaa gtggaaattc cttctccaac tcagaaggaa
721 aaggagaaaa agaaaagacc aatgtctcag atcagtggag tcaagaaatt gatgcacagc
781 tctagtctga ctaattcaag tatcccaagg tttggagtta aaactgaaca agaagatgtc
841 cttgccaagg aactagaaga tgtgaacaaa tggggtcttc atgttttcag aatagcagag
901 ttgtctggta accggccctt gactgttatc atgcacacca tttttcagga acgggattta
961 ttaaaaacat ttaaaattcc agtagatact ttaattacat atcttatgac tctcgaagac
1021 cattaccatg ctgatgtggc ctatcacaac aatatccatg ctgcagatgt tgtccagtct
1081 actcatgtgc tattatctac acctgctttg gaggctgtgt ttacagattt ggagattctt
1141 gcagcaattt ttgccagtgc aatacatgat gtagatcatc ctggtgtgtc caatcaattt
1201 ctgatcaata caaactctga acttgccttg atgtacaatg attcctcagt cttagagaac
1261 catcatttgg ctgtgggctt taaattgctt caggaagaaa actgtgacat tttccagaat
1321 ttgaccaaaa aacaaagaca atctttaagg aaaatggtca ttgacatcgt acttgcaaca
1381 gatatgtcaa aacacatgaa tctactggct gatttgaaga ctatggttga aactaagaaa
1441 gtgacaagct ctggagttct tcttcttgat aattattccg ataggattca ggttcttcag
1501 aatatggtgc actgtgcaga tctgagcaac ccaacaaagc ctctccagct gtaccgccag
1561 tggacggacc ggataatgga ggagttcttc cgccaaggag accgagagag ggaacgtggc
1621 atggagataa gccccatgtg tgacaagcac aatgcttccg tggaaaaatc acaggtgggc
1681 ttcatagact atattgttca tcccctctgg gagacatggg cagacctcgt ccaccctgac
1741 gcccaggata ttttggacac tttggaggac aatcgtgaat ggtaccagag cacaatccct
1801 cagagcccct ctcctgcacc tgatgaccca gaggagggcc ggcagggtca aactgagaaa
1861 ttccagtttg aactaacttt agaggaagat ggtgagtcag acacggaaaa ggacagtggc
1921 agtcaagtgg aagaagacac tagctgcagt gactccaaga ctctttgtac tcaagactca
1981 gagtctactg aaattcccct tgatgaacag gttgaagagg aggcagtagg ggaagaagag
2041 gaaagccagc ctgaagcctg tgtcatagat gatcgttctc ctgacacgta acagtgcaaa
2101 aactttcatg cctttttttt ttttaagtag aaaaattgtt tccaaagtgc atgtcacatg
2161 ccacaaccac ggtcacacct cactgtcatc tgccaggacg tttgttgaac aaaactgacc
2221 ttgactactc agtccagcgc tcaggaatat cgtaaccagt tttttcacct ccatgttcat
2281 ccgagcaagg tggacatctt cacgaacagc gtttttaaca agatttcagc ttggtagagc
2341 tgacaaagca gataaaatct actccaaatt attttcaaga gagtgtgact catcaggcag
2401 cccaaaagtt tattggactt ggggtttcta ttccttttta tttgtttgca atattttcag
2461 aagaaaggca ttgcacagag tgaacttaat ggacgaagca acaaatatgt caagaacagg
2521 acatagcacg aatctgttac cagtaggagg aggatgagcc acagaaattg cataattttc
2581 taatttcaag tcttcctgat acatgactga atagtgtggt tcagtgagct gcactgacct
2641 ctacattttg tatgatatgt aaaacagatt ttttgtagag cttactttta ttattaaatg
2701 tattgaggta ttatatttaa aaaaaactat gttcagaact tcatctgcca ctggttattt
2761 ttttctaagg agtaacttgc aagttttcag tacaaatctg tgctacactg gataaaaatc
2821 taatttatga attttacttg caccttatag ttcatagcaa ttaactgatt tgtagtgatt
2881 cattgtttgt tttatatacc aatgacttcc atattttaaa agagaaaaac aactttatgt
2941 tgcaggaaac cctttttgta agtctttatt atttactttg catt
//