LOCUS AF012073 3332 bp mRNA linear HUM 03-FEB-1998
DEFINITION Homo sapiens cAMP-specific phosphodiesterase PDE4D5 (PDE4D) mRNA,
complete cds.
ACCESSION AF012073
VERSION AF012073.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3332)
AUTHORS Bolger,G.B., Erdogan,S., Jones,R.E., Loughney,K., Scotland,G.,
Hoffmann,R., Wilkinson,I., Farrell,C. and Houslay,M.D.
TITLE Characterization of five different proteins produced by
alternatively spliced mRNAs from the human cAMP-specific
phosphodiesterase PDE4D gene
JOURNAL Biochem. J. 328 (Pt 2), 539-548 (1997)
PUBMED 9371713
REFERENCE 2 (bases 1 to 3332)
AUTHORS Bolger,G.B., Erdogan,S., Jones,R.E., Loughney,K., Scotland,G.,
Hoffman,R., Wilkinson,I., Farrell,C. and Houslay,M.D.
TITLE Direct Submission
JOURNAL Submitted (01-JUL-1997) Medicine (Heme/Onc), University of Utah,
Room 4C416, S.O.M., Salt Lake City, UT 84132, USA
FEATURES Location/Qualifiers
source 1..3332
/db_xref="H-InvDB:HIT000062227"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q13"
/clone="S3"
/cell_line="HeLa"
gene 1..3332
/gene="PDE4D"
CDS 118..2355
/gene="PDE4D"
/codon_start=1
/product="cAMP-specific phosphodiesterase PDE4D5"
/protein_id="AAC00069.1"
/translation="MAQQTSPDTLTVPEVDNPHCPNPWLNEDLVKSLRENLLQHEKSK
TARKSVSPKLSPVISPRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPL
DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVT
PFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLE
ELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDK
QHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKEL
EDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYH
ADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFL
INTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLA
TDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL
YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGES
DTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDD
RSPDT"
BASE COUNT 988 a 730 c 710 g 904 t
ORIGIN
1 gaattcggca cgagcagcag caggctcaga cctgcttccc tggacatttc cgggaccgtg
61 agcgagggaa ccacgttgcc ctggattctt gccagctgta caaagttgac caggaaaatg
121 gctcagcaga caagcccgga cactttaaca gtacctgaag tggataatcc gcattgtcca
181 aacccgtggc tgaacgaaga ccttgtgaaa tccttgcgag aaaacctgtt gcagcatgag
241 aagtccaaga cagcgaggaa atcggtttct cccaagctct ctccagtgat ctctccgaga
301 aattccccca ggcttctgcg cagaatgctt ctcagcagca acatccccaa acagcggcgt
361 ttcacggtgg cacatacatg ttttgatgtg gacaatggca catctgcggg acggagtccc
421 ttggatccca tgaccagccc aggatccggg ctaattctcc aagcaaattt tgtccacagt
481 caacgacggg agtccttcct gtatcgatcc gacagcgatt atgacctctc tccaaagtct
541 atgtcccgga actcctccat tgccagtgat atacacggag atgacttgat tgtgactcca
601 tttgctcagg tcttggccag tctgcgaact gtacgaaaca actttgctgc attaactaat
661 ttgcaagatc gagcacctag caaaagatca cccatgtgca accaaccatc catcaacaaa
721 gccaccataa cagaggaggc ctaccagaaa ctggccagcg agaccctgga ggagctggac
781 tggtgtctgg accagctaga gaccctacag accaggcact ccgtcagtga gatggcctcc
841 aacaagttta aaaggatgct taatcgggag ctcacccatc tctctgaaat gagtcggtct
901 ggaaatcaag tgtcagagtt tatatcaaac acattcttag ataagcaaca tgaagtggaa
961 attccttctc caactcagaa ggaaaaggag aaaaagaaaa gaccaatgtc tcagatcagt
1021 ggagtcaaga aattgatgca cagctctagt ctgactaatt caagtatccc aaggtttgga
1081 gttaaaactg aacaagaaga tgtccttgcc aaggaactag aagatgtgaa caaatggggt
1141 cttcatgttt tcagaatagc agagttgtct ggtaaccggc ccttgactgt tatcatgcac
1201 accatttttc aggaacggga tttattaaaa acatttaaaa ttccagtaga tactttaatt
1261 acatatctta tgactctcga agaccattac catgctgatg tggcctatca caacaatatc
1321 catgctgcag atgttgtcca gtctactcat gtgctattat ctacacctgc tttggaggct
1381 gtgtttacag atttggagat tcttgcagca atttttgcca gtgcaataca tgatgtagat
1441 catcctggtg tgtccaatca atttctgatc aatacaaact ctgaacttgc cttgatgtac
1501 aatgattcct cagtcttaga gaaccatcat ttggctgtgg gctttaaatt gcttcaggaa
1561 gaaaactgtg acattttcca gaatttgacc aaaaaacaaa gacaatcttt aaggaaaatg
1621 gtcattgaca tcgtacttgc aacagatatg tcaaaacaca tgaatctact ggctgatttg
1681 aagactatgg ttgaaactaa gaaagtgaca agctctggag ttcttcttct tgataattat
1741 tccgatagga ttcaggttct tcagaatatg gtgcactgtg cagatctgag caacccaaca
1801 aagcctctcc agctgtaccg ccagtggacg gaccggataa tggaggagtt cttccgccaa
1861 ggagaccgag agagggaacg tggcatggag ataagcccca tgtgtgacaa gcacaatgct
1921 tccgtggaaa aatcacaggt gggcttcata gactatattg ttcatcccct ctgggagaca
1981 tgggcagacc tcgtccaccc tgacgcccag gatattttgg acactttgga ggacaatcgt
2041 gaatggtacc agagcacaat ccctcagagc ccctctcctg cacctgatga cccagaggag
2101 ggccggcagg gtcaaactga gaaattccag tttgaactaa ctttagagga agatggtgag
2161 tcagacacgg aaaaggacag tggcagtcaa gtggaagaag acactagctg cagtgactcc
2221 aagactcttt gtactcaaga ctcagagtct actgaaattc cccttgatga acaggttgaa
2281 gaggaggcag taggggaaga agaggaaagc cagcctgaag cctgtgtcat agatgatcgt
2341 tctcctgaca cgtaacagtg caaaaacttt catgcctttt ttttttttaa gtagaaaaat
2401 tgtttccaaa gtgcatgtca catgccacaa ccacggtcac acctcactgt catctgccag
2461 gacgtttgtt gaacaaaact gaccttgact actcagtcca gcgctcagga atatcgtaac
2521 cagttttttc acctccatgt tcatccgagc aaggtggaca tcttcacgaa cagcgttttt
2581 aacaagattt cagcttggta gagctgacaa agcagataaa atctactcca aattattttc
2641 aagagagtgt gactcatcag gcagcccaaa agtttattgg acttggggtt tctattcctt
2701 tttatttgtt tgcaatattt tcagaagaaa ggcattgcac agagtgaact taatggacga
2761 agcaacaaat atgtcaagaa caggacatag cacgaatctg ttaccagtag gaggaggatg
2821 agccacagaa attgcataat tttctaattt caagtcttcc tgatacatga ctgaatagtg
2881 tggttcagtg agctgcactg acctctacat tttgtatgat atgtaaaaca gattttttgt
2941 agagcttact tttattatta aatgtattga ggtattatat ttaaaaaaaa ctatgttcag
3001 aacttcatct gccactggtt atttttttct aaggagtaac ttgcaagttt tcagtacaaa
3061 tctgtgctac actggataaa aatctaattt atgaatttta cttgcacctt atagttcata
3121 gcaattaact gatttgtagt gattcattgt ttgttttata taccaatgac ttccatattt
3181 taaaagagaa aaacaacttt atgttgcagg aaaccctttt tgtaagtctt tattatttac
3241 tttgcatttt gtttcactct ttccagataa gcagagttgc tcttcaccag tgtttttctt
3301 catgtgcaaa gtgactattt gttctataat ac
//