LOCUS AF011904 1288 bp mRNA linear HUM 11-APR-2000
DEFINITION Homo sapiens inwardly rectifying potassium channel Kir 2.1 (IRK1)
mRNA, complete cds.
ACCESSION AF011904
VERSION AF011904.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1288)
AUTHORS Tare,M., Prestwich,S.A., Gordienko,D.V., Parveen,S., Carver,J.E.,
Robinson,C. and Bolton,T.B.
TITLE Inwardly rectifying whole cell potassium current in human blood
eosinophils
JOURNAL J. Physiol. (Lond.) 506 (Pt 2), 303-318 (1998)
PUBMED 9490857
REFERENCE 2 (bases 1 to 1288)
AUTHORS Prestwich,S.A. and Bolton,T.B.
TITLE Direct Submission
JOURNAL Submitted (30-JUN-1997) Pharmacology and Clinical Pharmacology, St.
George's Hospital Medical School, Cranmer Terrace, London SW17 ORE,
UK
FEATURES Location/Qualifiers
source 1..1288
/db_xref="H-InvDB:HIT000062222"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="eosinophil"
/tissue_type="blood"
gene 1..1288
/gene="IRK1"
CDS 1..1284
/gene="IRK1"
/function="ion channel"
/note="HEos-IRK"
/codon_start=1
/product="inwardly rectifying potassium channel Kir 2.1"
/protein_id="AAC39555.1"
/translation="MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCR
SRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCV
FWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM
VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLR
KSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDED
SPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVFFEEK
HYYKVEYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSEN
GVPESTSTDTPPDIDLHNQASVPLEPRPLRRESEI"
BASE COUNT 347 a 293 c 330 g 318 t
ORIGIN
1 atgggcagtg tgcgaaccaa ccgctacagc atcgtctctt cagaagaaga cggtatgaag
61 ttggccacca tggcagttgc aaatggcttt gggaacggga agagtaaagt ccacacccga
121 caacagtgca ggagccgctt tgtgaagaaa gatggccact gtaatgttca gttcatcaat
181 gtgggtgaga aggggcaacg gtacctcgca gacatcttca ccacgtgtgt ggacattcgc
241 tggcggtgga tgctggttat cttctgcctg gctttcgtcc tgtcatggct gttttttggc
301 tgtgtgtttt ggttgatagc tctgctccat ggggacctgg atgcatccaa agagggcaaa
361 gcttgtgtgt ccgaggtcaa cagcttcacg gctgccttcc tcttctccat tgagacccag
421 acaaccatag gctatggttt cagatgtgtc acggatgaat gcccaattgc tgttttcatg
481 gtggtgttcc agtcaatcgt gggctgcatc atcgatgctt tcatcattgg cgcagtcatg
541 gccaagatgg caaagccaaa gaagagaaac gagactcttg tcttcagtca caatgccgtg
601 attgccatga gagacggcaa gctgtgtttg atgtggcgag tgggcaatct tcggaaaagc
661 cacttggtgg aagctcatgt tcgagcacag ctcctcaaat ccagaattac ttctgaaggg
721 gagtatatcc ctctggatca aatagacatc aatgttgggt ttgacagtgg aatcgatcgt
781 atatttctgg tgtccccaat cactatagtc catgaaatag atgaagacag tcctttatat
841 gatttgagta aacaggacat tgacaacgca gactttgaaa tcgtggtcat actggaaggc
901 atggtggaag ccactgccat gacgacacag tgccgtagct cttatctagc aaatgaaatc
961 ctgtggggcc accgctatga gcctgtgttc tttgaagaga agcactacta caaagtggag
1021 tattccaggt tccacaaaac ttacgaagtc cccaacactc ccctttgtag tgccagagac
1081 ttagcagaaa agaaatatat cctctcaaat gcaaattcat tttgctatga aaatgaagtt
1141 gccctcacaa gcaaagagga agacgacagt gaaaatggag ttccagaaag cactagtacg
1201 gacacgcccc ctgacataga ccttcacaac caggcaagtg tacctctaga gcccaggccc
1261 ttacggcgag agtcggagat atgactga
//