LOCUS AF011390 5322 bp mRNA linear HUM 09-JUL-1998
DEFINITION Homo sapiens pancreas sodium bicarbonate cotransporter mRNA,
complete cds.
ACCESSION AF011390
VERSION AF011390.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5322)
AUTHORS Abuladze,N., Lee,I., Newman,D., Hwang,J., Boorer,K., Pushkin,A. and
Kurtz,I.
TITLE Molecular cloning, chromosomal localization, tissue distribution,
and functional expression of the human pancreatic sodium
bicarbonate cotransporter
JOURNAL J. Biol. Chem. 273 (28), 17689-17695 (1998)
PUBMED 9651366
REFERENCE 2 (bases 1 to 5322)
AUTHORS Abuladze,N. and Kurtz,I.
TITLE Direct Submission
JOURNAL Submitted (27-JUN-1997) Medicine, UCLA, 10833 Le Conte Ave, Los
Angeles, CA 90095, USA
FEATURES Location/Qualifiers
source 1..5322
/db_xref="H-InvDB:HIT000062098"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q21"
CDS 118..3357
/codon_start=1
/product="pancreas sodium bicarbonate cotransporter"
/protein_id="AAC39840.1"
/translation="MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRR
HKRKTGHKEKKEKERISENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDS
PAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFE
LRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKK
SNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMK
KLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKA
KSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIE
PPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDI
KRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGT
AVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCL
ILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTL
FSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLV
GNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFC
VIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD
QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLK
METETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGV
ASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVA
AIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSD
NDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC"
BASE COUNT 1507 a 1113 c 1142 g 1560 t
ORIGIN
1 gcggcggcgg ccgcggtggc agcgaaggcg gcggcggcgg cggcagtggc agtggccgct
61 gcagccccac actccgccgc caaactggag gagcgacgga agccagaccc caggaggatg
121 gaggatgaag ctgtcctgga cagaggggct tccttcctca agcatgtgtg tgatgaagaa
181 gaagtagaag gccaccatac catttacatc ggagtccatg tgccgaagag ttacaggaga
241 aggagacgtc acaagagaaa gacagggcac aaagaaaaga aggaaaagga gagaatctct
301 gagaactact ctgacaaatc agatattgaa aatgctgatg aatccagcag cagcatccta
361 aaacctctca tctctcctgc tgcagaacgc atccgattca tcttgggaga ggaggatgac
421 agcccagctc cccctcagct cttcacggaa ctggatgagc tgctggccgt ggatgggcag
481 gagatggagt ggaaggaaac agccaggtgg atcaagtttg aagaaaaagt ggaacagggt
541 ggggaaagat ggagcaagcc ccatgtggcc acattgtccc ttcatagttt atttgagctg
601 aggacatgta tggagaaagg atccatcatg cttgatcggg aggcttcttc tctcccacag
661 ttggtggaga tgattgttga ccatcagatt gagacaggcc tattgaaacc tgaacttaag
721 gataaggtga cctatacttt gctccggaag caccggcatc aaaccaagaa atccaacctt
781 cggtccctgg ctgacattgg gaagacagtc tccagtgcaa gtaggatgtt taccaaccct
841 gataatggta gcccagccat gacccatagg aatctgactt cctccagtct gaatgacatt
901 tctgataaac cggagaagga ccagctgaag aataagttca tgaaaaaatt gccacgtgat
961 gcagaagctt ccaacgtgct tgttggggag gttgactttt tggatactcc tttcattgcc
1021 tttgttaggc tacagcaggc tgtcatgctg ggtgccctga ctgaagttcc tgtgcccaca
1081 aggttcttgt tcattctctt aggtcctaag gggaaagcca agtcctacca cgagattggc
1141 agagccattg ccaccctgat gtctgatgag gtgttccatg acattgctta taaagcaaaa
1201 gacaggcacg acctgattgc tggtattgat gagttcctag atgaagtcat cgtccttcca
1261 cctggggaat gggatccagc aattaggata gagcctccta agagtcttcc atcctctgac
1321 aaaagaaaga atatgtactc aggtggagag aatgttcaga tgaatgggga tacgccccat
1381 gatggaggtc acggaggagg aggacatggg gattgtgaag aattgcagcg aactggacgg
1441 ttctgtggtg gactaattaa agacataaag aggaaagcgc cattttttgc cagtgatttt
1501 tatgatgctt taaatattca agctctttcg gcaattctct tcatttatct ggcaactgta
1561 actaatgcta tcacttttgg aggactgctt ggggatgcca ctgacaacat gcagggcgtg
1621 ttggagagtt tcctgggcac tgctgtctct ggagccatct tttgcctttt tgctggtcaa
1681 ccactcacta ttctgagcag caccggacct gtcctagttt ttgagaggct tctatttaat
1741 ttcagcaagg acaataattt tgactatttg gagtttcgcc tttggattgg cctgtggtcc
1801 gccttcctat gtctcatttt ggtagccact gatgccagct tcttggttca atacttcaca
1861 cgtttcacgg aggagggctt ttcctctctg attagcttca tctttatcta tgatgctttc
1921 aagaagatga tcaagcttgc agattactac cccatcaact ccaacttcaa agtgggctac
1981 aacactctct tttcctgtac ctgtgtgcca cctgacccag ctaatatctc aatatctaat
2041 gacaccacac tggccccaga gtatttgcca actatgtctt ctactgacat gtaccataat
2101 actacctttg actgggcatt tttgtcgaag aaggagtgtt caaaatacgg aggaaacctc
2161 gtcgggaaca actgtaattt tgttcctgat atcacactca tgtcttttat cctcttcttg
2221 ggaacctaca cctcttccat ggctctgaaa aaattcaaaa ctagtcctta ttttccaacc
2281 acagcaagaa aactgatcag tgattttgcc attatcttgt ccattctcat cttttgtgta
2341 atagatgccc tagtaggcgt ggacacccca aaactaattg tgccaagtga gttcaagcca
2401 acaagtccaa accgaggttg gttcgttcca ccgtttggag aaaacccctg gtgggtgtgc
2461 cttgctgctg ctatcccggc tttgttggtc actatactga ttttcatgga ccaacaaatt
2521 acagctgtga ttgtaaacag gaaagaacat aaactcaaga aaggagcagg gtatcacttg
2581 gatctctttt gggtggccat cctcatggtt atatgctccc tcatggctct tccgtggtat
2641 gtagctgcta cggtcatctc cattgctcac atcgacagtt tgaagatgga gacagagact
2701 tctgcacctg gagaacaacc aaagtttcta ggagtgaggg agcaaagagt cactggaacc
2761 cttgtgttta ttctgactgg tctgtcagtc tttatggctc ccatcttgaa gtttataccc
2821 atgcctgtac tctatggtgt gttcctgtat atgggagtag catcccttaa tggtgtgcag
2881 ttcatggatc gtctgaagct gcttctgatg cctctgaagc atcagcctga cttcatctac
2941 ctgcgtcatg ttcctctgcg cagagtccac ctgttcactt tcctgcaggt gttgtgtctg
3001 gccctgcttt ggatcctcaa gtcaacggtg gctgctatca tttttccagt aatgatcttg
3061 gcacttgtag ctgtcagaaa aggcatggac tacctcttct cccagcatga cctcagcttc
3121 ctggatgatg tcattccaga aaaggacaag aaaaagaagg aggatgagaa gaaaaagaaa
3181 aagaagaagg gaagtctgga cagtgacaat gatgattctg actgcccata ctcagaaaaa
3241 gttccaagta ttaaaattcc aatggacatc atggaacagc aacctttcct aagcgatagc
3301 aaaccttctg acagagaaag atcaccaaca ttccttgaac gccacacatc atgctgataa
3361 aattcctttc cttcagtcac tcggtatgcc aagtcctcct agaactccag taaaagttgt
3421 gcctcaaatt agaatagaac ttgaacctga agacaatgat tatttctgga ggagcaaggg
3481 aacagaaact acattgtaac ctgtttgtct ttcttaaaac tgacatttgt tttaatgtca
3541 tttgtttttg tttggctgtt tgtttatttt ttaactttta tttcgtctca gtttttggtc
3601 acaggccaaa taatacagcg ctctctctgc ttctctcttg catagataca atcaagacaa
3661 tagtgcaccg ttccttaaaa acagcatctg aggaatcccc cttttgttct taaactttca
3721 gatgtgtcct ttgataacca aattctgtca ctcaagacac agacacccac agaccctgtc
3781 ctttgcctct attaagcaga ggatggaagt attaaggatt ttgtaacacc ttttatgaaa
3841 atgttgaagg aacttaaaac tttagctttg gagctgtgct tactggcttg tctttgtctg
3901 gtagaacaaa ccttgacctc cagacagagt cccttctcac ttatagagct ctccaggact
3961 ggaaaaagtg ctgctatttt aacttgctct tgcttgtaaa tcctaatctt agagttatca
4021 aaagaagaaa aaactgaagg tactttactc cctatagaga aaccattgcc atcattgtag
4081 caagtgctgg aatgtccctt ttttcctatg caactttttt taacccttta atgaacttat
4141 ctgttgagta cattgaagaa tatttttctt cctagatttt gttgtttaaa ttatggggcc
4201 taacctgcca cttatttttt gtcaattttt aaaacttttt tttaattact gtaaagaaaa
4261 tgaatttttt cctgcagcag gaaacatagt tttgagtagt tctacctctt atttgtagct
4321 gccaggcttt ctgtaaaaat tgtattgtat ataatgtgat ttttacacat acatacacac
4381 acaaatacac aatctctagg gtaagccaga aggcaagatc agattaaaaa caccatgttt
4441 ctaagcatcc atttttccct ttctttaaaa gaaacttaac tgttctatga aggagattga
4501 gggagaagag acaaactcct atgtcatgag aataaccgat gttctgataa tagtagcatc
4561 taggtacaga tgctggttgt attaccacgt caatgtccta tgcagtattg ttagacattt
4621 tctcattttg aaatatttgt gtgtttgtgt atgtgctctg tgccatggct ggtgtatata
4681 tgtgcaatgt tagaaggcaa aagagtgatg gtaggcagag ggcaaagtca ttgaatctct
4741 tatgccagtt ttcataaaac ccaaaccaca tatgaaaaaa tccattaagg gtccaagaag
4801 tctgtccata tgaaaatgag ggtaaatata gtttatttcc caggtatcag tcattataat
4861 tgatataata gctctaacat gcaatataaa attcatagga gtattaatag cccatttaca
4921 catctataaa atgtaatggg attgcagagc tgcagagtac agtgtaacag tactctcatg
4981 caattttttt caggatgcaa aggcaattat tctttgtaag cgggacattt agaatatatt
5041 tgtgtacata ttatatgtat gtatatttca aagtaccaca ctgaaaatta gacatttatt
5101 aaccaaattt aacgtggtat ttaaaggtaa tatttttaat atgatacatt acatattgtg
5161 aatgtatact aaaaaaacat tttaaatgtt aaaattataa tttcagattc atataaccac
5221 aactgtgata tatcctaact ataaccagtt gttgaggggt atactagaag cagaatgaaa
5281 ccacattttt tggtttgata atatgcactt attgactccc ac
//