LOCUS AF010313 2177 bp mRNA linear HUM 26-NOV-1999
DEFINITION Homo sapiens Pig8 (PIG8) mRNA, complete cds.
ACCESSION AF010313
VERSION AF010313.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2177)
AUTHORS Polyak,K., Xia,Y., Zweier,J.L., Kinzler,K.W. and Vogelstein,B.
TITLE A model for p53-induced apoptosis
JOURNAL Nature 389 (6648), 300-305 (1997)
PUBMED 9305847
REFERENCE 2 (bases 1 to 2177)
AUTHORS Polyak,K., Xia,Y., Zweier,J.L., Kinzler,K.W. and Vogelstein,B.
TITLE Direct Submission
JOURNAL Submitted (27-JUN-1997) Oncology, Johns Hopkins Oncology Center,
424 N. Bond St., Baltimore, MD 21231, USA
REFERENCE 3 (bases 1 to 2177)
AUTHORS Polyak,K.
TITLE Direct Submission
JOURNAL Submitted (26-NOV-1999) Adult Oncology, Dana-Farber Cancer
Institute, 44 Binney St. D740C, Boston, MA 02115, USA
REMARK Sequence update by submitter
COMMENT On Nov 26, 1999 this sequence version replaced AF010313.1.
FEATURES Location/Qualifiers
source 1..2177
/db_xref="H-InvDB:HIT000062083"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="DLD-1; colon cancer cell line"
gene 1..2177
/gene="PIG8"
CDS 73..1152
/gene="PIG8"
/note="p53 induced"
/codon_start=1
/product="Pig8"
/protein_id="AAC39531.2"
/translation="MIWGHFSLLCVVDSLGGEEMADSVKTFLQDLARGIKDSIWGICT
ISKLDARIQQKREEQRRRRASSVLAQRRPQSIERKQESEPRIVSRIFQCCAWNGGVFW
FSLLLFYRVFIPVLQSVTARIIGDPSLHGDVWSWLGFFLTSIFSAVWVLPLFVLSKVV
NAIWFQDIADLAFEVSGRKPHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLV
GQLVSLLHMSLLYSLYCFEYRWFNKGIEMHQRLSNIERNWPYYFGFGLPLAFLTAMQS
SYIISGCLFSILFPLFIISANEAKTPGKAYLFQLRLFSLVVFLSNRLFHKTVYLQSAL
SSSTSAEKFPSPHPSPAKLKATAGH"
BASE COUNT 516 a 487 c 515 g 659 t
ORIGIN
1 cggactggcc cgcggtgggc atggggcagg gccggagccg cggcggcgga gctgtggatc
61 cttcatgatg tgatgatttg gggacacttc tctctcctgt gtgtagttga tagtttgggt
121 ggtgaagaga tggctgacag tgtcaaaacc tttctccagg accttgccag aggaatcaaa
181 gactccatct ggggtatttg taccatctca aagctagatg ctcgaatcca gcaaaagaga
241 gaggagcagc gtcgaagaag ggcaagtagt gtcttggcac agagaagacc ccagagtata
301 gagcggaaac aagagagtga accacgtatt gttagtagaa ttttccagtg ttgtgcttgg
361 aatggtggag tgttctggtt cagtctcctc ttgttttatc gagtatttat tcctgtgctt
421 cagtcggtaa cagcccgaat tatcggtgac ccatcactac atggagatgt ttggtcgtgg
481 ctgggattct tcctcacgtc aattttcagt gctgtttggg tgctcccctt gtttgtgctt
541 agcaaagtgg tgaatgccat ttggtttcag gatatagctg acctggcatt tgaggtatca
601 gggaggaagc ctcacccatt ccctagtgtc agcaaaataa ttgctgacat gctcttcaac
661 cttttgctgc aggctctttt cctcattcag ggaatgtttg tgagtctctt tcccatccat
721 cttgtcggtc agctggttag tctcctgcat atgtcccttc tctactcact gtactgcttt
781 gaatatcgtt ggttcaataa aggaattgaa atgcaccagc ggttgtctaa catagaaagg
841 aattggcctt actactttgg gtttggtttg cccttggctt ttctcacagc aatgcagtcc
901 tcatatatta tcagtggctg cctcttttct atcctctttc ctttattcat tatcagcgcc
961 aatgaagcaa agacccctgg caaagcatat ctcttccagt tgcgcctatt ctccttggtg
1021 gtcttcttaa gcaacagact cttccacaag acagtctacc tgcagtcggc cctgagcagc
1081 tctacttctg cagagaagtt cccttcaccg catccgtcgc ctgccaaact gaaggctact
1141 gcaggtcact gagttgcctg ccatccaaag gggatgggcg ggattggaag aagctgtggc
1201 agctcttttc cctgttcacc tcccgcctgc cagggaaggc aggacccgct ctgccaaggg
1261 cccctctgcg tattcccttc tctctgagga attgaaattt ttgtctctgg tgcacgtaag
1321 gcagaatgtt ccctgacacc agtgtgtgga tttttaacat caccgtgagt ctgaaaggcc
1381 acaggttttt ctgcagctat tttctagcat ttgccagtcc ctgtgcctgg actgattgga
1441 acactttgtt tttctccctg tgccatttac ccttccacct ttccatcctg ccttctacca
1501 cccttggatg aatggatttt gtaattctag ctgttgtatt ttgtgaattt gttaattttg
1561 ttgtttttct gtgaaacaca tacattggat atgggaggta aaggagtgtc ccagttgctc
1621 ctggtcactc cctttatagc cattactgtc ttgtttcttg taactcaggt taggttttgg
1681 tctctcttgc tccactgcaa aaaaaaaaaa aaaaaaaaaa aaaagcctga agagatgaga
1741 taggaggaaa gaccttcaca gcccagatct gctgggtttt gaggagtgat tttctttcct
1801 ttcccttgaa ggggaaaaag ctattttcaa ttggtacatt taaagtcccc caactatggg
1861 gaggtaccaa ttctggacaa agtgccacta caacaacact aaacctgaac tttttcaact
1921 ccgttggtgg tgggaggcca gcgggcagaa atttactgtt ggccactgcc aggtctattt
1981 ccatatttca aaggaatatt gggtgctgca tataggaact gaaggggtca atgtattaaa
2041 cctgtgatta ggttgttttc ctgtcatttt tgagagacta aaattgtggg ggggcagatg
2101 ttcaaaatac ctggtacaag tttttaaaaa atggtcacaa ttaaacatga gctggtttcc
2161 caaataaaaa aaaaaaa
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