LOCUS AF009615 3410 bp mRNA linear HUM 27-SEP-1997
DEFINITION Homo sapiens ADAM10 (ADAM10) mRNA, complete cds.
ACCESSION AF009615
VERSION AF009615.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3410)
AUTHORS Rosendahl,M.S., Ko,S.C., Long,D.L., Brewer,M.T., Rosenzweig,B.,
Hedl,E., Anderson,L., Pyle,S.M., Moreland,J., Meyers,M.A.,
Kohno,T., Lyons,D. and Lichenstein,H.S.
TITLE Identification and characterization of a pro-tumor necrosis
factor-alpha-processing enzyme from the ADAM family of zinc
metalloproteases
JOURNAL J. Biol. Chem. 272 (39), 24588-24593 (1997)
PUBMED 9305925
REFERENCE 2 (bases 1 to 3410)
AUTHORS Lichenstein,H.S.
TITLE Direct Submission
JOURNAL Submitted (20-JUN-1997) Inflammation, Amgen, 3200 Walnut St.,
Boulder, CO 80301, USA
FEATURES Location/Qualifiers
source 1..3410
/db_xref="H-InvDB:HIT000062032"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3410
/gene="ADAM10"
CDS 470..2716
/gene="ADAM10"
/codon_start=1
/product="ADAM10"
/protein_id="AAC51766.1"
/translation="MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQ
KHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHI
YTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDD
INYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAE
KNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIR
INTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVG
APSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSP
HDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNN
CFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQG
PCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQ
CAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSGRTI
TLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVL
LMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRES
YQMGHMRR"
BASE COUNT 1006 a 682 c 830 g 892 t
ORIGIN
1 gaattcgagg atccgggtac catgggcggc ggcaggccta gcagcacggg aaccgtcccc
61 cgcgcgcatg cgcgcgcccc tgaagcgcct gggggacggg tatgggcggg aggtaggggc
121 gcggctccgc gtgccagttg ggtgcccgcg cgtcacgtgg tgaggaagga ggcggaggtc
181 tgagtttcga gggagggggg gagagaagag ggaacgagca agggaaggaa agcggggaaa
241 ggaggaagga aacgaacgag ggggagggag gtccctgttt tggaggagct aggagcgttg
301 ccggcccctg aagtggagcg agagggaggt gcttcgccgt ttctcctgcc aggggaggtc
361 ccggcttccc gtggaggctc cggaccaagc cccttcagct tctccctccg gatcgatgtg
421 ctgctgttaa cccgtgagga ggcggcggcg gcggcagcgg cagcggaaga tggtgttgct
481 gagagtgtta attctgctcc tctcctgggc ggcggggatg ggaggtcagt atgggaatcc
541 tttaaataaa tatatcagac attatgaagg attatcttac aatgtggatt cattacacca
601 aaaacaccag cgtgccaaaa gagcagtctc acatgaagac caatttttac gtctagattt
661 ccatgcccat ggaagacatt tcaacctacg aatgaagagg gacacttccc ttttcagtga
721 tgaatttaaa gtagaaacat caaataaagt acttgattat gatacctctc atatttacac
781 tggacatatt tatggtgaag aaggaagttt tagccatggg tctgttattg atggaagatt
841 tgaaggattc atccagactc gtggtggcac attttatgtt gagccagcag agagatatat
901 taaagaccga actctgccat ttcactctgt catttatcat gaagatgata ttaactatcc
961 ccataaatac ggtcctcagg ggggctgtgc agatcattca gtatttgaaa gaatgaggaa
1021 ataccagatg actggtgtag aggaagtaac acagatacct caagaagaac atgctgctaa
1081 tggtccagaa cttctgagga aaaaacgtac aacttcagct gaaaaaaata cttgtcagct
1141 ttatattcag actgatcatt tgttctttaa atattacgga acacgagaag ctgtgattgc
1201 ccagatatcc agtcatgtta aagcgattga tacaatttac cagaccacag acttctccgg
1261 aatccgtaac atcagtttca tggtgaaacg cataagaatc aatacaactg ctgatgagaa
1321 ggaccctaca aatcctttcc gtttcccaaa tattggtgtg gagaagtttc tggaattgaa
1381 ttctgagcag aatcatgatg actactgttt ggcctatgtc ttcacagacc gagattttga
1441 tgatggcgta cttggtctgg cttgggttgg agcaccttca ggaagctctg gaggaatatg
1501 tgaaaaaagt aaactctatt cagatggtaa gaagaagtcc ttaaacactg gaattattac
1561 tgttcagaac tatgggtctc atgtacctcc caaagtctct cacattactt ttgctcacga
1621 agttggacat aactttggat ccccacatga ttctggaaca gagtgcacac caggagaatc
1681 taagaatttg ggtcaaaaag aaaatggcaa ttacatcatg tatgcaagag caacatctgg
1741 ggacaaactt aacaacaata aattctcact ctgtagtatt agaaatataa gccaagttct
1801 tgagaagaag agaaacaact gttttgttga atctggccaa cctatttgtg gaaatggaat
1861 ggtagaacaa ggtgaagaat gtgattgtgg ctatagtgac cagtgtaaag atgaatgctg
1921 cttcgatgca aatcaaccag agggaagaaa atgcaaactg aaacctggga aacagtgcag
1981 tccaagtcaa ggtccttgtt gtacagcaca gtgtgcattc aagtcaaagt ctgagaagtg
2041 tcgggatgat tcagactgtg caagggaagg aatatgtaat ggcttcacag ctctctgccc
2101 agcatctgac cctaaaccaa acttcacaga ctgtaatagg catacacaag tgtgcattaa
2161 tgggcaatgt gcaggttcta tctgtgagaa atatggctta gaggagtgta cgtgtgccag
2221 ttctgatggc aaagatgata aagaattatg ccatgtatgc tgtatgaaga aaatggaccc
2281 atcaacttgt gccagtacag ggtctgtgca gtggagtagg cacttcagtg gtcgaaccat
2341 caccctgcaa cctggatccc cttgcaacga ttttagaggt tactgtgatg ttttcatgcg
2401 gtgcagatta gtagatgctg atggtcctct agctaggctt aaaaaagcaa tttttagtcc
2461 agagctctat gaaaacattg ctgaatggat tgtggctcat tggtgggcag tattacttat
2521 gggaattgct ctgatcatgc taatggctgg atttattaag atatgcagtg ttcatactcc
2581 aagtagtaat ccaaagttgc ctcctcctaa accacttcca ggcactttaa agaggaggag
2641 acctccacag cccattcagc aaccccagcg tcagcggccc cgagagagtt atcaaatggg
2701 acacatgaga cgctaactgc agcttttgcc ttggttcttc ctagtgccta caatgggaaa
2761 acttcactcc aaagagaaac ctattaagtc atcatctcca aactaaaccc tcacaagtaa
2821 cagttgaaga aaaaatggca agagatcata tcctcagacc aggtggaatt acttaaattt
2881 taaagcctga aaattccaat ttgggggtgg gaggtggaaa aggaacccaa ttttcttatg
2941 aacagatatt tttaacttaa tggcacaaag tcttagaata ttattatgtg ccccgtgttc
3001 cctgttcttc gttgctgcat tttcttcact tgcaggcaaa cttggctctc aataaacttt
3061 taccacaaat tgaaataaat atattttttt caactgccaa tcaaggctag gaggctcgac
3121 cacctcaaca ttggagacat cacttgccaa tgtacatacc ttgttatatg cagacatgta
3181 tttcttacgt acactgtact tctgtgtgca attgtaaaca gaaattgcaa tatggatgtt
3241 tctttgtatt ataaaatttt tccgctctta attaaaaatt actgtttaat tgacatactc
3301 aggataacag agaatggtgg tattcagtgg tccaggattc tgtaatgctt tacacaggca
3361 gttttgaaat gaaaatcaat ttaccccatg gtacccggat cctcgaattc
//