LOCUS AF009425 8440 bp mRNA linear HUM 17-FEB-1998
DEFINITION Homo sapiens clone 22 mRNA, alternative splicing variant alpha-2,
complete cds.
ACCESSION AF009425
VERSION AF009425.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8440)
AUTHORS Yoshikawa,T., Sanders,A.R., Esterling,L.E., Overhauser,J.,
Garnes,J.A., Lennon,G., Grewal,R. and Detera-Wadleigh,S.D.
TITLE Isolation of chromosome 18-specific brain transcripts as positional
candidates for bipolar disorder
JOURNAL Am. J. Med. Genet. 74 (2), 140-149 (1997)
PUBMED 9129712
REFERENCE 2 (bases 1 to 8440)
AUTHORS Yoshikawa,T., Sanders,A.R., Esterling,L.E. and Detera-Wadleigh,S.D.
TITLE Multiple transcriptional variants and RNA editing in C18orf1, a
novel gene with LDLRA and transmembrane domains on 18p11.2
JOURNAL Genomics 47 (2), 246-257 (1998)
PUBMED 9479497
REFERENCE 3 (bases 1 to 8440)
AUTHORS Yoshikawa,T. and Detera-Wadleigh,S.D.
TITLE Direct Submission
JOURNAL Submitted (20-JUN-1997) Clinical Neurogenetics Branch, National
Institute of Mental Health, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..8440
/db_xref="H-InvDB:HIT000062028"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18p11.2"
CDS 470..1336
/note="alternatively spliced; alpha-2 form; possible
membrane-spanning protein"
/codon_start=1
/product="clone 22"
/protein_id="AAC52024.1"
/translation="MPEAGFQATNAFTECKFTCTSGKCLYLGSLVCNQQNDCGDNSDE
ENCLLVTEHPPPGIFNSELEFAQIIIIVVVVTVMVVVIVCLLNHYKVSTRSFINRPNQ
SRRREDGLPQIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPTISLSDGE
EPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSNSG
ISASTCSSNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTIVP
IKGKDRKPGNLV"
BASE COUNT 2278 a 1882 c 1885 g 2393 t
ORIGIN
1 agcggttcaa gctctacgtt cgtgacatca aacctcctgt tgggccattt ccgagaactc
61 ccatcagttt ctgtatagtg taaaagtttc agaggcggac acgagagagc tgcggctggg
121 acaaggagca cccgcgtgca ggtgcgaccc tgcaggatgc tggcagcggc gtggccaggg
181 gcgcccgtgt tctgagggcc tgagggccag cccctccacc cgcgccatgg cctccgcgcc
241 ctggctggac ggctgacggg agcagggacc gccgccgccc aggtgccaca cccaggtacc
301 gcccgcccgc tgcgagagcc gggcaggtgg gccgcggatg ctcccagagg ccggcccagc
361 agagcgatgg acttggacag gctaagatgg aagtgacctg agcctcgccc ggcggcttcc
421 tcgacgggac agcgcaagag ttggagcaca ggcttgtccg gggagcagta tgccggaagc
481 tggttttcag gccacaaatg ctttcacaga gtgcaaattc acctgcacca gtggtaaatg
541 cttgtatctt ggttcgctgg tctgtaacca acagaacgac tgtggggaca acagtgacga
601 agagaactgt ctcctggtga ccgagcaccc gcctccgggc atcttcaact cggagctgga
661 gttcgcccaa atcatcatca tcgtcgtggt ggtcacggtg atggtggtgg tcatcgtctg
721 cctgctgaac cactacaaag tctccacgcg gtccttcatc aaccgcccga accagagccg
781 gaggcgggag gacgggctgc cgcagatcat gcatgccccg cggtccaggg acaggttcac
841 agcgccgtcc ttcatccaga gggatcgctt cagccgcttc cagcccacct acccctatgt
901 gcagcacgag attgatcttc ctcccaccat ctccctgtcc gacggtgaag agccacctcc
961 ttaccagggg ccctgcaccc tgcagctccg ggaccctgaa cagcagatgg aactcaaccg
1021 agagtccgtg agggccccac ccaaccgaac catatttgac agtgatttaa tagacattgc
1081 tatgtatagc gggggtccat gcccacccag cagcaactcg ggcatcagtg caagcacctg
1141 cagcagtaac gggaggatgg aggggccacc ccccacatac agcgaggtga tgggccacca
1201 cccaggcgcc tctttcctcc atcaccagcg cagcaacgca cacaggggca gcagactgca
1261 gtttcagcag aacaatgcag agagcacaat agtacccatc aaaggcaaag ataggaagcc
1321 tgggaacctg gtctgattcc ttccaacgtg cacttcagct ggagaaagaa accaagaagg
1381 gaagcggccg ctgggcccct cctgcgcaca gtgttgttca gtttcacatg gtacaaataa
1441 gtaaaaccaa atgagcaaac acggtctttg tttctgattc cttttagggg aattgcatgc
1501 aaactagact gaaatgatac aaacttccat ctggtctgac cgcaaacagt gtttatttgg
1561 ggacaggggt tgggatgggg gtgtgggcag gggaaaacag agaacgggat gctttgaaga
1621 taccatgaaa taaaacccac agaggtattt gatgtattta attgtgaaag gagactttgc
1681 agataaatga ggccagaatg gcatgtttta taattaactg aataaagaag gaagcattat
1741 tatatattat tgtggggaag aaccagccag ttcgcttttt ctcctaaggt gtggactttt
1801 attttgtttt aaaaatatga atcaaaattc ctgtgttgtg tgccaaggta taaagtggag
1861 aagttagatg agtgcaagga gctcctttgt gttgtgatga tgtgttttaa aagttgcact
1921 atcttaatgt tgaaaatatt tacaagggaa ctgttttacg tgaagttctg tatgttgtct
1981 tttcacctgt ggattgtaat caggcccaag gaatatcctg gagtggtccc cagaagcatc
2041 caagaaaaga tatttgggga cgtagcctaa cattttacca acttacgtaa atcaaaaaag
2101 tcattattgt tgcaggagtt tgcatcaaat agcagtgcat cgctgaagct tttggagact
2161 tttggatgga agataagata gggaagatta agttccagca tttctgactt gttattttga
2221 gttactctgc tactcttagg ctgcatagtt tatgagaaaa tgaacacatg catttatgga
2281 tccagtatca tgcagtgctg ccctcatcct ccagcagtgc aatttcttca gtaatttaga
2341 tttttttcac tatagcatga aatatattca aatacatacc ttattttatg caataaattg
2401 tttaaaatgc aaggtggtta ttctgcatac tgttgaaata tgtgactcct cagtatattc
2461 ccattgcctc tccccctttc ctcgacagct tagttcagtt ctgcagggct gctcagttca
2521 caggaggctc ccagcagcca ccccacatcc agcctacaca gaactttcgt gtgggagtgg
2581 tgtgggtggt ggttttctta tgctttggaa gcccctagaa ataatgacgg aagaatgcca
2641 tgttgctgat cgtggtaata agccattgtg ggttattgta tgtcactagt attagcatag
2701 cattcttaaa ggaatgcagt gttcaaaacc tacccaaatt ccccgcagga ttttaccaaa
2761 cccttcccca ggccagtttt gtactgaagg caagaactgg acagtcagag aacagtggag
2821 ggggcaagtg actgaagagc accgggtaaa aagcacaaca tgcagttaaa atgcaaacta
2881 gaaaactaat tttaaatatt gttagtttta atatttcctg atatttacaa atattcattc
2941 ttatatacaa tgaaaaaaat aactttcttc tgcagatgta agcactggct tttataagag
3001 cagcagccaa cacgtttagc agacactgcg cgtggagaag ggcttatctg cagtacactc
3061 tgccatgtgg agggtgggcc tctgtggcct cttcacataa caagatgagc tggaatgatg
3121 attccatgac tcccacctat gcagccttaa agccaaatcc gcgtgtgtgt gtttgtgtct
3181 gtctgtgggt ctcgaaggtg atccgtcggt gcggtggctc tgtgctgtaa ctggagagac
3241 tgttccaaac cccaagagtt gtctgatcct agtctgttcc cttctgcttc ttacctctgt
3301 agataggtca ctggtttttg tttgtttgtt ttgaggattg gaatttccat tacattcatc
3361 ctttgcacac agtaacatcc acagaactag tccaactctt aaaaggagag aggaaaaaca
3421 caggcaccag ttgtcagctc atgcttacaa cctgtgtgga agtatataca gttgagagtc
3481 acagtggagg ttctgagact ggattcagtc ttgttccagt gacagttgga aggcctctgc
3541 tggagagaca ccagctctca gggcagagat tggcttgggg ccagaaggac cctccccaac
3601 cctggagaca ccctgaaggt tcactggctc tccagattag cctctcttcc tctgtcaggc
3661 aaagatgagg agcccgtgtt cccatcgggc cctgctggca gggacttgca gtggattctt
3721 ggtcaggtgt gcccacagat gcggaggcga ggtgagtgat tccatcattt cagttctcac
3781 ctgcagtttt ggtgaagcag gagatgcacc ccacagctct agctctcaaa tggcttcaca
3841 gtccttactt ctctacctgc ctcaagaagg ggctcagagc agagacttgt gaattcctta
3901 gtaactgtga gtatatgaat gtgttgcaca tgtccacagt attggcgaga taattacata
3961 attcagatac ctttaatcat ctttcaagaa agaggctcct cccattcaac caccctagag
4021 aactgccttt gttaaatagt tatttaaaga ctcatacata tcaaaccatg actttgaaag
4081 gtcttcgagg ctggggctct gtaatgaatt agtttaaaag ccaaggtcat aacatgaatt
4141 gatggtcaat ttcccttcag cagaaggaaa aggtgattta gatcagtagc tcttttgaag
4201 gttgtggctg acctgttcat accgtgtcgc ctcatggcta gtgtggcgtt gaaagagtag
4261 cgactgggaa gatacaactt acacagtggg gcctattgtt ctttcaagaa cccttttttt
4321 agcttataga acccatgggt ccagtttagt aacgagtgat ttaggcaatc aatgataggt
4381 ttataatctt agattattcc agcaaagtgt ggattgcatt gttaggaaga acatttggtg
4441 ggaatgaaca ctcctgggca taccgctgac ttttgtccct tgttcccggt gtaggagacc
4501 caaggcatct tgaatcccat ctataagaac acaatcttcc agcatacgtt tgctttttca
4561 gaaactctag cattctcttt aaatactgac gcaatcctta atggaaaaga gatttcatga
4621 agcaaattat gtatttcaat agttcttcta tttttagtgt ccaaaattta ctaatacaga
4681 agcttgacaa gcatgtcctc accctcccca ccacataaac acatggacac acacccaagc
4741 cacaagaaat cccaagagag cagaagcgaa tttttaaaag atttatcgtg aggactgcat
4801 ttccattcac taattttggc tcaaacttat gaggcaggaa ataggggcca acagtaaatg
4861 ggggaggcct cctgacacca gcagaggaat tttgtaccca ggcgaggact tcttgaactt
4921 ctgcgtatct ccgtttgatc tctttcacct ttatttcatc ttcataagaa tgagaaaggc
4981 tcaaaaggaa gcacttttag aaatcttctc tgacctagaa gaatccatcc aaatccctgc
5041 cttcctctct gaaccaacag ttcccttctc tgacaggggg ccatcctcta tcttccatcc
5101 agcggctctt ccttttagga aggctctggt gcagagcact tcaaatatgt cctcaggcca
5161 gatactgatt gctagtagag agacacccgg cacccagtcc gaagccctcc ctcaaaggac
5221 cggcttatgg cgttggtcac tggcaggctc agagacattc tactgtgggc gcagggagcc
5281 cggcccccca tgcagccatg actggatgcg cccccatctc gggggcttgc tgcactgctt
5341 gtttattgaa ttttgctact tagaatggca acattaactt tgtgtaccat tcatttttta
5401 aaaattttcc aaagctcggc agtgtatgaa agaaaaaact gggaaagata cttggtttct
5461 gttaactttt gtgttgcttg cttaagtgat taaagccagt gcttggagcc aagccttcat
5521 gccacgaaca tgctccacag cctgcccttt gctctcctgc tcacactgac caagaatgcc
5581 gcgtgcttgg cctactgagg tgaaaggaca attgaatgac aggtgggcaa agggagaact
5641 tccccttctt ggtgcgagga aagtcacaaa tttaaaaatg ttgcttccag cccagatcct
5701 aaatgctagt tctcagcagc tgcgtggctt accgttcgcc atttccacca ccgccagctg
5761 ccagcaccgc tacagatcac agagatgtga acagacaatg gaaagcactc ttagccttgc
5821 agtggtctac attttttagg aaccaatatt tcagcattct ttattacccg gcacgctgtg
5881 tcctttgcag agttcaagtt tatgttactg ccagggtcag acagtcattt gctgctgctg
5941 ctgctgctgc tgctgcttct cgaactggat gcattaggaa gctgctgtct gagtgtagga
6001 atgtcttgct aagaaagcaa tgtcttcctt catccttttc tttcttccct ctgcgtgtcc
6061 ttgtttttgt gtaatgcggg agagggttag agctatagag attatatata cactatccgt
6121 gcacattata tatatgtaga tataccccta tcatgtcaga gatctgcatg tcagtttttc
6181 agcaactaag gtgcctcatg ttctgagttc agcagatata ggaaccaagc cgccccctcc
6241 tgcacttgat gctcccacct ttgttgtgcc tcacttaaaa tggtgctttt ttcagttgtc
6301 tgtcttttct tatgttttta tttgtaaggt gctgtatata agttgaatat attatgcaca
6361 tatcctaccc aatgggtaga acaaaaagtt gttaatactg taatataatg tatagatgat
6421 accaatttta acagaaatgg catagaattt gtgaatgcct atgtgctttg tcctcttttg
6481 taaggaaatt tgcaaatgga tgcatacaga ttaaagtcta tgtagtttat tttcctatta
6541 aatatcaata ttataacaca agagaaagaa gtgtgaacaa acaagcaaca gtttatgacc
6601 agcgtatata tagcaatgga aagttgcatc tttgctgtga aaacacttta aagaaaatac
6661 tttttaaaaa atcccacagc tttttggttg ccactagacg cttcttattt taatcatttt
6721 agtaatgctc agctggacca gtgttagtta tatttgagtc agaaaaatgt tgtttttcaa
6781 cttgctttat aatctcctgc atctatctcc tgctgtagca tcaygaaggt gtcaggcaac
6841 agtgaaaagt gcacattttt gttgttgcag aaactgtgtc agaggaataa gtaaatcagc
6901 ctgcagcaga agactttgtt cagctccaga ggcatctgtg accgtctgtg tccaagtctc
6961 tctgtgcctt tttcttttac aaactgaagc tgtggagcca atgaagtaac agtagagatt
7021 gtagggaaag aatacctcag gaaaaacaaa tacacttaca agaagaccct gttcttagaa
7081 aatgtgttta gttatgggtt agcactagaa gagacttggc tgtcagccag ccaagtgaag
7141 gacctctcat ccattcccat tcatgtccca tcataatacg gacmcaaaaa gcaaactcgg
7201 ttttgccatc agttagaaat tacgttttgg attgtatatt gttacatctc tcttccagct
7261 tagtttttag tgtctgattg tgacctctgc atttatcttc aaatacccta attttaaaac
7321 aaaagaacaa gaaaagttta taacaccatg ttcactaaaa ccacggttga atcttgggtg
7381 tgggcatcct ttcgagtgtt gtccataaga gcagttcgtg gaattttgcc catctgaccc
7441 atattatcag cttattctgc caccagagta gagtctaata aattccaaag tttttatttg
7501 ctccatggtg tatgttctga ctttgaaaat gtcagattct ataatcatac ccctaacatc
7561 caggagacaa atgacagatt atctttaaac tgaaattgac tctacaatgc aacccttaat
7621 gctgaatgga ttaaaaaagt cagccctttt agtatctgtt tgaaagggcc gtaaaaagtt
7681 gacacttttg ttgttgtgga tcctgcgtgt ctagacccac gtgttgtttc catcgtatac
7741 tgtagggtgc accccttggg attcatcatt aagaactgag gctcactgtt gtcagaaaca
7801 aagctcccac cccccaggtt caaccttgtg ggagaactgt tgagcatgag aatgttctag
7861 actcagaggt actaaaattt gttaccacat cattgcttcc tttctacagg acgaattgag
7921 gcttaaactt tactgttaat gatactggtt cattttaatg tgcttgttgg tatgttgcta
7981 tttttcattt catagctttc aaaaatcatg ctaattgtat acttgtctag tttaaggcta
8041 ttttaaaata tgtacaatac tattcacagc atttagttcg tttaattttt attataaagc
8101 aatctactaa aaaagtacaa ctgtatttga acttttcaat agttgtttgt gagctatgat
8161 aatcaaaagt cattaaagtc ttttttaaca aacattcgtg cttacttttc aacataattc
8221 ccagttatat acagaaaaag atttccacct gtcacgtatc tgcctctttt acctgagcaa
8281 tggtgtagtt cttagaccta aggtctgtaa ttgcaatact tttaaagaaa gatgttgctc
8341 taagtgctgt ttgttagtta tgaaatcaga tttttctgct tgttcttaat gctgtggtca
8401 aaccatagca caaaatcatt aaaaataatc agcggcatac
//