LOCUS AF009353 3039 bp mRNA linear HUM 22-JUL-1997
DEFINITION Homo sapiens transcription intermediary factor 1 (TIF1) mRNA,
complete cds.
ACCESSION AF009353
VERSION AF009353.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3039)
AUTHORS Thenot,S., Henriquet,C., Rochefort,H. and Cavailles,V.
TITLE Differential interaction of nuclear receptors with the putative
human transcriptional coactivator hTIF1
JOURNAL J. Biol. Chem. 272 (18), 12062-12068 (1997)
PUBMED 9115274
REFERENCE 2 (bases 1 to 3039)
AUTHORS Thenot,S., Henriquet,C., Rochefort,H. and Cavailles,V.
TITLE Direct Submission
JOURNAL Submitted (19-JUN-1997) INSERM U148, 60 rue de Navacelles,
Montpellier 34090, France
FEATURES Location/Qualifiers
source 1..3039
/db_xref="H-InvDB:HIT000062025"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="ZR75-1"
/cell_type="estrogen receptor positive breast cancer cell"
gene 1..3039
/gene="TIF1"
CDS 1..3039
/gene="TIF1"
/note="interacts with nuclear receptors which contain
hormone-dependent activating function (AF2); involved in
transcriptional regulation"
/codon_start=1
/product="transcription intermediary factor 1"
/protein_id="AAB63585.1"
/translation="MEVAVEKAVAAAARLGCAPGGPRGGGENEAESRQGPDSERGGEA
ARLNLLDTCAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPV
PAPARRSASSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCT
SCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVF
CPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEK
TKYIKFTGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDH
RMKLMQQQQEVTGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDA
SPVTNNTIQFHCDPSFWAQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSN
QLSKFPTQISLAQLRLQHMQQQQPPPRLINFQNHSPKPNGPVLPPHPQQLRYPPNQNI
PRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYNGKAF
GSPIIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPN
SSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPI
RIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVL
RSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGG
ELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKT
EGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRL
QEDYSMYSKPEDFVRDFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRF
PKPEFRNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK"
BASE COUNT 941 a 738 c 664 g 696 t
ORIGIN
1 atggaggtgg cggtggagaa ggcggtggcg gcggcggcac ggctcggctg cgctccgggg
61 ggccctcggg gcggcgggga gaacgaggcc gagagtcggc agggcccgga ctcggagcgc
121 ggcggcgagg cggcccggct caacctgttg gacacttgcg ccgtgtgcca ccagaacatc
181 cagagccggg cgcccaagct gctgccctgc ctgcactctt tctgccagcg ctgcctgccc
241 gcgccccagc gctacctcat gctgcccgcg cccatgctgg gctcggccga gaccccgcca
301 cccgtccctg ccccggctcg ccggtcagcc tcgtcgccgt tcgccaccca agttggagtc
361 attcgttgcc cagtttgcag ccaagaatgt gcagagagac acatcataga taactttttt
421 gtgaaggaca ctactgaggt tcccagcagt acagtagaaa agtcaaatca ggtatgtaca
481 agctgtgagg acaacgcaga agccaatggg ttttgtgtag agtgtgttga atggctctgc
541 aagacgtgta tcagagctca tcagagggta aagttcacaa aagaccacac tgtcagacag
601 aaagaggaag tatctccaga ggcagttggt gtcaccagcc agcgaccagt gttttgtcct
661 tttcataaaa aggagcagct gaagctgtac tgtgagacat gtgacaaact gacatgtcga
721 gactgtcagt tgttagaaca taaagagcat agataccaat ttatagaaga agcttttcag
781 aatcagaaag tgatcataga tacactaatc accaaactga tggaaaaaac aaaatacata
841 aaattcacag gaaatcagat ccaaaacaga attattgaag taaatcaaaa tcaaaagcag
901 gtggaacagg atattaaagt tgctatattt acactgatgg tagaaataaa taaaaaagga
961 aaagctctac tgcatcagtt agagagcctt gcaaaggacc atcgcatgaa acttatgcaa
1021 caacaacagg aagtgactgg actctctaaa caattggagc atgtcatgca tttttctaaa
1081 tgggcagttt ccagtggcag cagtacagca ttactttata gcaaacgact gattacatac
1141 cggttacggc acctccttcg tgcaaggtgt gatgcatccc cagtgaccaa caacaccatc
1201 caatttcact gtgatcctag tttctgggct caaaatatca tcaacttagg ttctttagta
1261 atcgaggata aagagagcca gccacaaatg cctaagcaga atcctgtcgt ggaacagaat
1321 tcacagccac caagtggttt atcatcaaac cagttatcca agttcccaac acagatcagc
1381 ctagctcaat tacggctcca gcatatgcag caacagcaac cgcctccacg tttgataaac
1441 tttcagaatc acagccccaa acccaatgga ccagttcttc ctcctcatcc tcaacaactg
1501 agatatccac caaaccagaa cataccacga caagcaataa agccaaaccc cctacagatg
1561 gctttcttgg ctcaacaagc cataaaacag tggcagatca gcagtggaca gggaacccca
1621 tcaactacca acagcacatc ctctactcct tccagcccca cgattactag tgcagcagga
1681 tataatggaa aggcttttgg ttcacctata atcgatttga gctcaccagt gggagggtct
1741 tataatcttc cctctcttcc ggatattgac tgttcaagta ctattatgct ggacaatatt
1801 gtgaggaaag atactaatat agatcatggc cagccaagac caccctcaaa cagaacggtc
1861 cagtcaccaa attcatcagt gccatctcca ggccttgcag gacctgttac tatgactagt
1921 gtacaccccc caatacgttc acctagtgcc tccagcgttg gaagccgagg aagctctggc
1981 tcttccagca aaccagcagg agctgactct acacacaaag tcccagtggt catgctggag
2041 ccaattcgaa taaaacaaga aaacagtgga ccaccggaaa attatgattt cccagttgtt
2101 atagtgaagc aagaatcaga tgaagaatct aggcctcaaa atgccaatta tccaagaagc
2161 atactcacct ccctgctctt aaatagcagt cagagctcta cttctgagga gactgtgcta
2221 agatcagatg cccctgatag tacaggagat caacctggac ttcaccagga caattcctca
2281 aatggaaagt ctgaatggtt ggatccttcc cagaagtcac ctcttcatgt tggagagaca
2341 aggaaagagg atgaccccaa tgaggactgg tgtgcagttt gtcaaaacgg aggggaactc
2401 ctctgctgtg aaaagtgccc caaagtattc catctttctt gtcatgtgcc cacattgaca
2461 aattttccaa gtggagagtg gatttgcact ttctgccgag acttatctaa accagaagtt
2521 gaatatgatt gtgatgctcc cagtcacaac tcagaaaaaa agaaaactga aggccttgtt
2581 aagttaacac ctatagataa aaggaagtgt gagcgcctac ttttatttct ttactgccat
2641 gaaatgagcc tggcttttca agaccctgtt cctctaactg tgcctgatta ttacaaaata
2701 attaaaaatc caatggattt gtcaaccatc aagaaaagac tacaagaaga ttattccatg
2761 tactcaaaac ctgaagattt tgtacgtgat tttagattga tctttcaaaa ctgtgctgaa
2821 ttcaatgagc ctgattcaga agtagccaat gctggtataa aacttgaaaa ttattttgaa
2881 gaacttctaa agaacctcta tccagaaaaa aggtttccca aaccagaatt caggaatgaa
2941 tcagaagata ataaatttag tgatgattca gatgatgact ttgtacagcc ccggaagaaa
3001 cgcctcaaaa gcattgaaga acgccagttg cttaaataa
//