LOCUS AF007790 2167 bp mRNA linear HUM 02-AUG-1999
DEFINITION Homo sapiens ICERE-1 mRNA, complete cds.
ACCESSION AF007790
VERSION AF007790.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2167)
AUTHORS Thompson,D.A. and Weigel,R.J.
TITLE Characterization of a gene that is inversely correlated with
estrogen receptor expression (ICERE-1) in breast carcinomas
JOURNAL Eur. J. Biochem. 252 (1), 169-177 (1998)
PUBMED 9523727
REFERENCE 2 (bases 1 to 2167)
AUTHORS Thompson,D.A.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-1997) Surgery, Stanford, 1201 Welch Road, MSLS
Building, Room P228, Stanford, CA 94305, USA
REFERENCE 3 (bases 1 to 2167)
AUTHORS Thompson,D.A.
TITLE Direct Submission
JOURNAL Submitted (02-AUG-1999) Surgery, Stanford, 1201 Welch Road, MSLS
Building, Room P228, Stanford, CA 94305, USA
REMARK Sequence update by submitter
COMMENT On Aug 2, 1999 this sequence version replaced AF007790.1.
FEATURES Location/Qualifiers
source 1..2167
/db_xref="H-InvDB:HIT000061912"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MDA-MB-231"
/cell_type="adenocarcinoma"
/tissue_type="breast"
gene 1..2167
/gene="ICERE-1"
CDS 481..1479
/gene="ICERE-1"
/note="expression inversely correlated with estrogen
receptor expression in breast cancer"
/codon_start=1
/protein_id="AAC39635.2"
/translation="MQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVV
LEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFI
DMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELL
MVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQL
FMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLK
DTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS"
BASE COUNT 573 a 476 c 555 g 563 t
ORIGIN
1 gcaaccagga attttcttag agaagttgat gctgatggtg acctgattgc agtatcaaat
61 ctgaatgact ctgataagtt acagcttcta agtctggtga caaaaaagaa gagattctgg
121 tgctggcaga gacccaagta ccagttttta tccctcaccc ttggcgatgt actcatagaa
181 gaccaatttc cgagtccagt ggtcgtggag tcggactttg tgaaatacga gggcaagttt
241 gcaaaccacg tgagtggaac cctggagact gcactgggga aggtcaagct gaacctgggg
301 ggcagcagcc gcgtagagag ccagtcttca tttggaaccc tgaggaagca ggaggtggat
361 ttgcagcagc tcatcagaga ctctgccgag agaacaataa atctgagaaa ccctgtgctc
421 cagcaggtgc tggagggaag gaatgaggtc ctgtgcgttt tgacacagaa gatcacgacg
481 atgcagaagt gtgtgatctc tgagcacatg caggtcgagg agaagtgtgg tggcatcgtg
541 ggcatccaga ccaagacggt gcaggtgtca gcgacggagg atgggaatgt caccaaggac
601 tccaacgtgg tgctggagat cccagctgcc accaccattg cctacggtgt cattgagtta
661 tacgtgaaac tggacggcca gttcgagttc tgccttctcc gagggaagca aggtggcttc
721 gagaacaaga agagaattga ctctgtctac ctggaccccc tggtctttcg agagtttgca
781 ttcatagaca tgccagatgc tgcgcatggg atatcttccc aggatggacc attaagtgtt
841 ttaaagcaag cgaccctgct cctggagagg aatttccatc catttgcgga gctgcctgag
901 ccacaacaga cagctttgag tgacatcttc caggcggtcc tatttgatga tgaactactc
961 atggtcctgg aaccagtgtg cgatgacctg gtcagcggcc tctcgcccac agtggcggtg
1021 ctgggggagc tgaagccccg gcagcagcag gaccttgtgg ccttcctgca gctggtgggg
1081 tgcagcttac agggtgggtg tccgggcccc gaggatgcag gcagcaagca gctgtttatg
1141 acagcctact tcttggtcag tgccctcgca gaaatgccag atagcgcggc agctctgctg
1201 ggcacttgct gcaaactcca gatcattccc acactgtgcc acttgcttcg tgctctgtct
1261 gatgatggag tatctgatct tgaagaccca accttgactc ccctgaaaga tacagaaagg
1321 tttgggattg tgcagcgctt gtttgcctca gctgacatta gtctggagag actgaagtca
1381 tctgtgaaag ctgtcattct gaaggactct aaagtcttcc cactgcttct ttgtataacc
1441 ctgaatggac tctgtgcttt aggcagagaa cattcatgat gtcatatgtg aactagaagt
1501 acgtgttact ggccaaggct atttttcaga actgttaaag gtcatatgca cgttaaaagt
1561 tgaccaatga aatgatttac agaacagttt aagaagtggt gacattttgc atgatgaatg
1621 acctgacttt tagccaccag gtactcttta aacagttttc cttatcagag gccctcctgt
1681 gctggtgacc cagcatctga gttaggttcc agcatgtaaa gagctgggag ggcggagaat
1741 tcttagcata cattcagacg ttttttctgc acaataataa gtccatctgt cacttgcatt
1801 ccactttttg ttacatagaa agagtctgac cctttaatcc aaaaggtctt tttacattgt
1861 gaatgctgtg ggaaggcaat ttctctgcac acaagaggct acgttttgga agtgatgtat
1921 gttatttgat gactgaaaat gaactgtaaa tgctcctaga gtatattcct ctgctgaaca
1981 aaattaaact tcaaaaaaat ctaacagtaa cacacccctg cttgggaccc tagctatatg
2041 cattttatgt gaccttgcca tgcttcagtg aacatactaa ttctatgtct agcacatgtt
2101 gatttcctat gtattctggg tattctatta aaggaaactt tgaactaaaa aaaaaaaaaa
2161 aaaaaaa
//