LOCUS AF006823 2590 bp mRNA linear HUM 06-OCT-1997
DEFINITION Homo sapiens TWIK-related acid-sensitive K+ channel (TASK) mRNA,
complete cds.
ACCESSION AF006823
VERSION AF006823.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2590)
AUTHORS Duprat,F., Lesage,F., Fink,M., Reyes,R., Heurteaux,C. and
Lazdunski,M.
TITLE TASK, a human background K+ channel to sense external pH variations
near physiological pH
JOURNAL EMBO J. 16 (17), 5464-5471 (1997)
PUBMED 9312005
REFERENCE 2 (bases 1 to 2590)
AUTHORS Duprat,F., Lesage,F., Fink,M., Reyes,R., Heurteaux,C. and
Lazdunski,M.
TITLE Direct Submission
JOURNAL Submitted (05-JUN-1997) IMPC, CNRS, 660 Route des Lucioles,
Sophia-Antipolis, Valbonne 06560, France
FEATURES Location/Qualifiers
source 1..2590
/db_xref="H-InvDB:HIT000061858"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2590
/gene="TASK"
CDS 126..1310
/gene="TASK"
/note="pore-forming K+ channel subunit"
/codon_start=1
/product="TWIK-related acid-sensitive K+ channel"
/protein_id="AAC51777.1"
/translation="MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELR
QQELRARYNLSQGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPS
TDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMV
LIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQP
QYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGG
GSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLS
TSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLHSLSTFRGLMKRRS
SV"
BASE COUNT 502 a 829 c 789 g 470 t
ORIGIN
1 tgccctgcgc ggagagcggc gagcgcagcc atgccccagg ccgcctccgg ggcagcagca
61 gcggcggccg gggccgatgc gcgggccggg ggcgccgggg ggccggcggc ggcccgggcg
121 ggacgatgaa gcggcagaac gtgcgcacgc tggcgctcat cgtgtgcacc ttcacctacc
181 tgctggtggg cgccgcggtc ttcgacgcgc tggagtcgga gcccgagctg atcgagcggc
241 agcggctgga gctgcggcag caggagctgc gggcgcgcta caacctcagc cagggcggct
301 acgaggagct ggagcgcgtc gtgctgcgcc tcaagccgca caaggccggc gtgcagtggc
361 gcttcgccgg ctccttctac ttcgccatca ccgtcatcac caccatcggc tacgggcacg
421 cggcacccag cacggatggc ggcaaggtgt tctgcatgtt ctacgcgctg ctgggcatcc
481 cgctcacgct cgtcatgttc cagagcctgg gcgagcgcat caacaccttg gtgaggtacc
541 tgctgcaccg cgccaagaag gggctgggca tgcggcgcgc cgacgtgtcc atggccaaca
601 tggtgctcat cggcttcttc tcgtgcatca gcacgctgtg catcggcgcc gccgccttct
661 cccactacga gcactggacc ttcttccagg cctactacta ctgcttcatc accctcacca
721 ccatcggctt cggcgactac gtggcgctgc agaaggacca ggccctgcag acgcagccgc
781 agtacgtggc cttcagcttc gtctacatcc ttacgggcct cacggtcatc ggcgccttcc
841 tcaacctcgt ggtgctgcgc ttcatgacca tgaacgccga ggacgagaag cgcgacgccg
901 agcaccgcgc gctgctcacg cgcaacgggc aggcgggcgg cggcggaggg ggtggcagcg
961 cgcacactac ggacaccgcc tcatccacgg cggcagcggg cggcggcggc ttccgcaacg
1021 tctacgcgga ggtgctgcac ttccagtcca tgtgctcgtg cctgtggtac aagagccgcg
1081 agaagctgca gtactccatc cccatgatca tcccgcggga cctctccacg tccgacacgt
1141 gcgtggagca gagccactcg tcgccgggag ggggcggccg ctacagcgac acgccctcgc
1201 gacgctgcct gtgcagcggg gcgccacgct ccgccatcag ctcggtgtcc acgggtctgc
1261 acagcctgtc caccttccgc ggcctcatga agcgcaggag ctccgtgtga ctgccccgag
1321 ggacctggag cacctggggg cgcgggcggg ggacccctgc tgggaggcca ggagactgcc
1381 cctgctgcct tctgcccagt gggaccccgc acaacatccc tcaccactct cccccagcac
1441 ccccatctcc gactgtgcct gcttgcacca gccggcagga ggccgggctc tgaggacccc
1501 tggggccccc atcggagccc tgcaaattcc gagaaatgtg aaacttggtg gggtcaggga
1561 ggaaaggcag aagctgggag cctcccttcc ctttgaaaat ctaagaagct cccagtcctc
1621 agagaccctg ctggtaccac accccacctt cggaggggac ttcatgttcc gtgtacgttt
1681 gcatctctat ttatacctct gtcctgctag gtctcccacc ttcccttggt tccaaaagcc
1741 agggtgtcta tgtccaagtc acccctactc agccccactc cccttcctca tccccagctg
1801 tgtctcccaa cctcccttcg tgttgttttg catggctttg cagttatgga gaaagtggaa
1861 acccagcagt ccctaaagct ggtccccaga aagcaggaca gaaagaagga gggacaggca
1921 ggcagcagga ggggcgagct gggaggcagg aggcagcggc ctgtcagtct gcagaatggt
1981 cgcactggag gttcaagcta actggcctcc agccacattc tcatagcagg taggacttca
2041 gccttccaga cactgccctt agaatctgga acagaagact tcagactcac cataattgct
2101 gataattacc cactcttaaa tttgtcgagt gatttttagc ctctgaaaac tctatgctgg
2161 ccactgattc ctttgagtct cacaaaaccc tacttaggtc atcagggcag gagttctcac
2221 tcccatttta cagatgagaa tactgaggcc tggacaggtg aagtgaccag agagcaaaag
2281 gcaaaggggt gggggctggg tgcagtggct cacacctgta ttcccaacac ttttggaggc
2341 tgaggttgga ggattgcttg agcccaggaa ttcgagacca gcctaggtga catagtgaga
2401 ccccatctct acaaaaaata aaaaattaac caggtgtggt ggcacgtgcc tgggagtccc
2461 agcgacttgg gaggctgagg tgggaggatt gtttgagcct gggaggtcga ggctgtagtg
2521 agccctgatt gcaccactgt actccagcct gggtgacagg gcaagaccct gtctcaaaaa
2581 aaaaaaaaaa
//