LOCUS HUMIMPA6 1694 bp mRNA linear HUM 21-NOV-1997
DEFINITION Homo sapiens importin alpha 6 mRNA, complete cds.
ACCESSION AF005361
VERSION AF005361.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1694)
AUTHORS Kohler,M., Ansieau,S., Prehn,S., Leutz,A., Haller,H. and
Hartmann,E.
TITLE Cloning of two novel human importin-alpha subunits and analysis of
the expression pattern of the importin-alpha protein family
JOURNAL FEBS Lett. 417 (1), 104-108 (1997)
PUBMED 9395085
REFERENCE 2 (bases 1 to 1694)
AUTHORS Kohler,M., Prehn,S. and Hartmann,E.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-1997) Zellbiologie, Max-Delbrueck-Centrum fuer
Molekulare Medizin, Robert-Roessle-Str.10, Berlin 13125, Germany
COMMENT On Aug 27, 1997 this sequence version replaced gi:2226365.
FEATURES Location/Qualifiers
source 1..1694
/db_xref="H-InvDB:HIT000061795"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 6..1616
/function="involved in NLS-dependent protein import into
the nucleus"
/note="importin alpha isoform; belongs to importin alpha
protein family; most closely related to human SRP1"
/codon_start=1
/product="importin alpha 6"
/protein_id="AAC51868.1"
/translation="MASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQL
FKRRNVYLPRNDESMLESPIQDSDISSTVPIPEEGVVTTDMVQMIFSNNADQQLTATQ
KFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHT
KVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELL
TNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWAL
SYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN
CSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEF
RTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILR
LGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEDD
PSIVPQVDENQQQFIFQQQEAPMDGFQL"
BASE COUNT 564 a 287 c 351 g 492 t
ORIGIN
1 atgccatggc tagtccaggg aaagataact atagaatgaa aagttataag aataaagccc
61 taaatcctca agagatgcgt agacgaagag aagaagaagg aatacagctt agaaaacaaa
121 aaagagaaga acagttgttc aaacgcagaa atgtctattt gcccagaaat gatgaatcta
181 tgcttgaaag tcctatacag gattcagata ttagttccac tgtacccatt ccagaggaag
241 gagttgttac tacagatatg gttcaaatga ttttttctaa taatgctgat caacagctaa
301 cagcaacaca gaaatttaga aagctgcttt ctaaagaacc taatccacca atagatcaag
361 ttatacagaa accaggagtt gtacagagat ttgtgaaatt tcttgaaaga aatgaaaatt
421 gcactttaca atttgaagct gcatgggcat taacaaatat agcatctgga acttttctgc
481 ataccaaggt agtgattgaa actggggctg ttccgatttt tatcaaactt cttaattctg
541 aacatgaaga tgttcaggaa caggctgttt gggcacttgg taatattgct ggtgacaatg
601 cagaatgcag agattttgtt ttgaattgtg aaatacttcc acctctttta gagttattaa
661 caaattcaaa cagactcaca acaacaagaa atgccgtgtg ggccctctca aatttatgta
721 gaggcaaaaa ccctcctcca aactttagta aggtttcacc ttgcttaaat gtcctgtcac
781 gactgttgtt tagcagtgac ccagatgtgt tagcagacgt gtgttgggcc ctttcttatc
841 tttccgatgg acccaatgat aaaattcaag cagtcattga ttctggagtc tgtcgaagat
901 tggtggaact tttgatgcac aatgattata aagttgtatc acctgcatta agggcagttg
961 gtaatattgt gactggtgat gatattcaaa cacaggtaat tttgaattgt tctgcattac
1021 cctgtctctt acatttattg agtagcccaa aggagtcaat tagaaaagaa gcctgctgga
1081 ctgtttctaa catcactgct ggaaatagag ctcagattca ggctgttata gatgcaaata
1141 tttttcctgt tttgattgag attcttcaga aagcagagtt tcgtaccaga aaagaagcag
1201 cttgggctat aactaatgca acatcaggag gtactccaga gcaaataagg tatttggtag
1261 ctttaggctg cattaaacca ctttgtgatc ttttgactgt tatggactcc aaaatagtcc
1321 aagtggcttt aaatggactt gaaaatattt tacgtcttgg agaacaagaa tctaagcaga
1381 atggaatagg cattaatcca tactgtgctc tcattgaaga agcatatggt ctggataaaa
1441 ttgagttttt gcaaagccat gaaaatcagg aaatttacca gaaggcattt gatctgattg
1501 aacattactt tggtgtagaa gaagatgacc ccagcattgt acctcaggtg gatgaaaacc
1561 aacaacagtt tatatttcag cagcaggaag caccaatgga tggatttcaa ctttaactta
1621 ctggaggaaa aaaaatttat ggctaaaaag ggtagcttca ggtaactcct ctttgttgcc
1681 aatgtaagga actg
//