LOCUS AF004021 3095 bp mRNA linear HUM 16-JUL-1997
DEFINITION Homo sapiens prostaglandin F2 alpha receptor mRNA, complete cds.
ACCESSION AF004021
VERSION AF004021.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3095)
AUTHORS Kunapuli,P., Lawson,J.A., Hwang,S.W., Adiyaman,M., Khanapure,S.P.,
Rokach,J. and FitzGerald,G.A.
TITLE Functional Characterization of the Ocular PGF2 alpha Receptor.
Activation by the Isoprostane, 12-iso-PGF2 alpha
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3095)
AUTHORS Kunapuli,P. and FitzGerald,G.A.
TITLE Direct Submission
JOURNAL Submitted (13-MAY-1997) Center for Experimental Therapeutics,
University of Pennsylvania, 905 Stellar Chance Labs, 422 Curie
Blvd., Philadelphia, PA 19104, USA
FEATURES Location/Qualifiers
source 1..3095
/db_xref="H-InvDB:HIT000061728"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="ocular ciliary body"
CDS 152..1231
/note="G protein-coupled receptor; PGF2 alpha receptor"
/codon_start=1
/product="prostaglandin F2 alpha receptor"
/protein_id="AAB63152.1"
/translation="MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSN
SLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFD
QSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVC
LFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLL
CNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGING
NHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWE
LSSIKNSLKVAAISESPVAEKSAST"
BASE COUNT 906 a 584 c 625 g 980 t
ORIGIN
1 ggcgcggggc gccatggcac accgagcggc tccgtcttct gctcctcaga gagcccggct
61 ggcggcctgg gatgacaaga tgtctggact gcaatcctgc acagttttga gagggagatg
121 acttgagtgg ttggctttta tctccacaac aatgtccatg aacaattcca aacagctagt
181 gtctcctgca gctgcgcttc tttcaaacac aacctgccag acggaaaacc ggctttccgt
241 atttttttca gtaatcttca tgacagtggg aatcttgtca aacagccttg ccatcgccat
301 tctcatgaag gcatatcaga gatttagaca gaagtccaag gcatcgtttc tgcttttggc
361 cagcggcctg gtaatcactg atttctttgg ccatctcatc aatggagcca tagcagtatt
421 tgtatatgct tctgataaag aatggatccg ctttgaccaa tcaaatgtcc tttgcagtat
481 ttttggtatc tgcatggtgt tttctggtct gtgcccactt cttctaggca gtgtgatggc
541 cattgagcgg tgtattggag tcacaaaacc aatatttcat tctacgaaaa ttacatccaa
601 acatgtgaaa atgatgttaa gtggtgtgtg cttgtttgct gttttcatag ctttgctgcc
661 catccttgga catcgagact ataaaattca ggcgtcgagg acctggtgtt tctacaacac
721 agaagacatc aaagactggg aagatagatt ttatcttcta cttttttctt ttctggggct
781 cttagccctt ggtgtttcat tgttgtgcaa tgcaatcaca ggaattacac ttttaagagt
841 taaatttaaa agtcagcagc acagacaagg cagatctcat catttggaaa tggtaatcca
901 gctcctggcg ataatgtgtg tctcctgtat ttgttggagc ccatttctgg ttacaatggc
961 caacattgga ataaatggaa atcattctct ggaaacctgt gaaacaacac tttttgctct
1021 ccgaatggca acatggaatc aaatcttaga tccttgggta tatattcttc tacgaaaggc
1081 tgtccttaag aatctctata agcttgccag tcaatgctgt ggagtgcatg tcatcagctt
1141 acatatttgg gagcttagtt ccattaaaaa ttccttaaag gttgctgcta tttctgagtc
1201 accagttgca gagaaatcag caagcaccta gcttaatagg acagtaaatc tgtgtggggc
1261 tagaacaaaa attaagacat gtttggcaat atttcagtta gttaaatacc tgtagcctaa
1321 ctggaaaatt caggcttcat catgtagttt gaagatacta ttgtcagatt caggttttga
1381 aatttgtcaa ataaacagga taactgtaca ttttcaactt gtttttgcca atgggaggta
1441 gacacaataa aataatgcca tgggagtcac actgaaagca attttgagct tatctgtctt
1501 atttatgctt tgagtgaatc atctgttgag gtctaatgcc tctacttggc ctatttgcca
1561 gagaacatct taatgcagcc tgcatagtga aatggttatt ttgagatcac cgctctgtag
1621 ctaaccctta taaactaggc tcagtaaaat aaagcactct tattttttga tctggcctat
1681 tttgcccctc attgtgtagc ctcaattaac acatgcatgg tcatgacacc cagaattcat
1741 gatggtttgt tataacaacc tctgcatatt ccaggtctgg cagacaggtt gcctgaccct
1801 gcaatcctat ctagaatggg cccattcttg tcacatttga caaataggac tgcctacatt
1861 tattattatg aaggtcgatt gttgttggaa gtgttttttc atgtcataga ttagcaattt
1921 tcaaataatt attttttctc tgaaaatttt gtgtgtgatt gcacaataaa taatttttag
1981 agaaacaaag gctctttctc agcacattga tgggcaacta gaattacagc agtttcaaac
2041 tctaccatgg ataatgcaaa caaaccgaag ctacatgcca atgataggtg caaagaatat
2101 tggcaaaagg tgctttacct tgagccatta tttgtgtcag agaacaaaag aaacagaatc
2161 aatatataaa ttcaaagact atctgcagct agtgtgtttc ttctttacac acatatacac
2221 acagacatca gaaaattctg ttgagagcag gttcattaaa tttgtaagat ggcatattct
2281 aaagcctgtg ctaccagtac taagagggga agactggcaa tttgccaagc acttggggat
2341 tattataaca attaactagg agatcaagag ataataatct ctccccaaat tttccaataa
2401 taattgagac tttttctttg cttgtttgtg taattcaacc aaaagaattt caatacccat
2461 tcaaattgtc ctaggtctat cagaaattag ggaaggtagt cctgctttat aataggaaaa
2521 tgtatttctg tataagattt ctttgctttc attaaaaatg ggattcattt aaaaattaat
2581 ctttccctgt taggctgatt tcagattctc taggaaatct ggtgaagtaa ccagaagact
2641 ttcagatggt ttatttgctt tcagcagaga atttatttca tacagttact taagagtgtt
2701 gatgtcttgt gaacagagat ataaggaacc attctccatc cttccttatc atgctgggta
2761 caatgcttct atgaatattt ccatgtattt tgactgggga gaggcatgga gaagaaactc
2821 tcattcaggg gctccaggat ccttctcctt gaggcttcta aataaatggc agaattcttg
2881 ctgtattgcc atgatgtcac cctggccatg tgtactgact tgaggagatc ttgcaacatg
2941 gccatgtgca aggctttaag gagtgagaga gatgtgtaca tatcttagga gggttatcta
3001 tgttatctga gtatatgttt gggtaaccaa attggtctta aaaatgatgt taacccaaga
3061 agtagacatc aaaaattaaa aaaaaaaaaa aaaaa
//