LOCUS AF003595 1368 bp mRNA linear HUM 09-AUG-2004
DEFINITION Homo sapiens 8-oxoguanine DNA glycosylase 1 (OGG1) mRNA, complete
cds.
ACCESSION AF003595
VERSION AF003595.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1368)
AUTHORS Lu,R., Nash,H.M. and Verdine,G.L.
TITLE A mammalian DNA repair enzyme that excises oxidatively damaged
guanines maps to a locus frequently lost in lung cancer
JOURNAL Curr. Biol. 7 (6), 397-407 (1997)
PUBMED 9197244
REFERENCE 2 (bases 1 to 1368)
AUTHORS Lu,R., Nash,H.M. and Verdine,G.L.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-1997) Chemistry and Chemical Biology, Harvard
University, 12 Oxford St., Cambridge, MA 02138, USA
FEATURES Location/Qualifiers
source 1..1368
/db_xref="H-InvDB:HIT000061719"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p25-p26"
gene 1..1368
/gene="OGG1"
CDS 57..1094
/gene="OGG1"
/function="glycosylase/lyase specific for excision of
7,8-dihydro-8-oxoguanine from DNA"
/note="hOgg1"
/codon_start=1
/product="8-oxoguanine DNA glycosylase 1"
/protein_id="AAB61340.1"
/translation="MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQS
FRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQL
DVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVE
RLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEE
QGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQ
RDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLRQSRHAQEPPA
KRRKGSKGPEG"
BASE COUNT 304 a 411 c 383 g 270 t
ORIGIN
1 cgacgaggcc tggttctggg taggcggggc tactacgggg cggtgctgct gtggaaatgc
61 ctgcccgcgc gcttctgccc aggcgcatgg ggcatcgtac tctagcctcc actcctgccc
121 tgtgggcctc catcccgtgc cctcgctctg agctgcgcct ggacctggtt ctgccttctg
181 gacaatcttt ccggtggagg gagcaaagtc ctgcacactg gagtggtgta ctagcggatc
241 aagtatggac actgactcag actgaggagc agctccactg cactgtgtac cgaggagaca
301 agagccaggc tagcaggccc acaccagacg agctggaggc cgtgcgcaag tacttccagc
361 tagatgttac cctggctcaa ctgtatcacc actggggttc cgtggactcc cacttccaag
421 aggtggctca gaaattccaa ggtgtgcgac tgctgcgaca agaccccatc gaatgccttt
481 tctcttttat ctgttcctcc aacaacaaca tcgcccgcat cactggcatg gtggagcggc
541 tgtgccaggc ttttggacct cggctcatcc agcttgatga tgtcacctac catggcttcc
601 ccagcctgca ggccctggct gggccagagg tggaggctca tctcaggaag ctgggcctgg
661 gctatcgtgc ccgttacgtg agtgccagtg cccgagccat cctggaagaa cagggcgggc
721 tagcctggct gcagcagcta cgagagtcct catatgagga ggcccacaag gccctctgca
781 tcctgcctgg agtgggcacc aaggtggctg actgcatctg cctgatggcc ctagacaagc
841 cccaggctgt gcccgtggat gtccatatgt ggcacattgc ccaacgtgac tacagctggc
901 accctaccac gtcccaggcg aagggaccga gcccccagac caacaaggaa ctgggaaact
961 ttttccggag cctgtgggga ccttatgctg gctgggccca agcggtgctg ttcagtgccg
1021 acctgcgcca atcccgccat gctcaggagc caccagcaaa gcgcagaaag ggttccaaag
1081 ggccggaagg ctagatgggg caccctggac aaagaaattc cccaagcacc ttcccctcca
1141 ttccccactt ctctctcccc atccccaccc agtctcatgt tggggagggg cctccctgtg
1201 actacctcaa aggccaggca cccccaaatc aagcagtcag tttgcacaac aagatggggt
1261 gggggatatt gagggagaca gcgctaagga tggttttatc ttccctttat tacaagaagg
1321 aacaataaaa tagaaacatt tgtatggaaa aaaaaaaaaa aaaaaaaa
//