LOCUS AF003092 1248 bp mRNA linear HUM 18-FEB-2004
DEFINITION Homo sapiens alpha-2,8-sialyltransferase III mRNA, complete cds.
ACCESSION AF003092
VERSION AF003092.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1248)
AUTHORS Angata,K., Suzuki,M., McAuliffe,J., Ding,Y., Hindsgaul,O. and
Fukuda,M.
TITLE Differential biosynthesis of polysialic acid on neural cell
adhesion molecule (NCAM) and oligosaccharide acceptors by three
distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II
(STX), and ST8Sia III
JOURNAL J. Biol. Chem. 275 (24), 18594-18601 (2000)
PUBMED 10766765
REFERENCE 2 (bases 1 to 1248)
AUTHORS Angata,K. and Fukuda,M.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-1997) Glycobiology, The Burnham Institute, 10901
North Torrey Pines Road, La Jolla, CA 92037, USA
REFERENCE 3 (bases 1 to 1248)
AUTHORS Angata,K. and Fukuda,M.
TITLE Direct Submission
JOURNAL Submitted (18-FEB-2004) Glycobiology, The Burnham Institute, 10901
North Torrey Pines Road, La Jolla, CA 92037, USA
REMARK Sequence update by submitter
COMMENT On Feb 18, 2004 this sequence version replaced AF003092.1.
FEATURES Location/Qualifiers
source 1..1248
/db_xref="H-InvDB:HIT000061706"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q21"
/tissue_type="brain"
/dev_stage="fetal"
CDS 73..1215
/note="ST8Sia III"
/codon_start=1
/product="alpha-2,8-sialyltransferase III"
/protein_id="AAC15901.2"
/translation="MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKY
ASPGAPRMYMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQ
EILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYN
ICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKY
YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLA
WPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDL
PYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA"
BASE COUNT 351 a 308 c 264 g 325 t
ORIGIN
1 tacacgccag cgagctgctg gccgctcaat ggaccgattt ccccggtttc catgaaccca
61 gcccagcccg ggatgagaaa ctgcaaaatg gcccgggtcg ccagtgtgct ggggctggtc
121 atgctcagcg tcgccctgct gattttatcg ctcatcagct acgtgtccct gaaaaaggag
181 aacatcttca ccactcccaa gtacgccagc ccgggggcgc cccgaatgta catgttccac
241 gcgggattcc ggtcacaatt tgcgctgaag tttctagacc cgtcattcgt gcccattacg
301 aattctctca cccaggaact ccaagagaaa ccttctaagt ggaaatttaa tcggacagcg
361 tttttacatc aaaggcaaga aattcttcag catgtcgatg taataaaaaa tttttctttg
421 accaagaata gtgttcggat tggacaactg atgcactatg attattccag ccataaatat
481 gttttctcta ttagcaataa cttccggtca cttcttccag atgtgtcacc cattatgaac
541 aagcattata atatttgtgc tgtggttgga aatagtggga tcctgacagg gagccagtgt
601 ggacaagaaa tagataaatc agattttgtt ttccgttgca atttcgcccc tacggaggct
661 ttccaaagag atgttggaag aaaaaccaat cttaccacct tcaaccccag catcctggaa
721 aaatattaca acaatctctt gactattcag gaccgtaaca actttttcct cagtttaaaa
781 aagcttgacg gggccattct ttggatccct gcatttttct tccacacttc agcaactgtg
841 accaggacat tagttgactt ttttgttgaa cacagaggtc agttaaaagt ccaactggct
901 tggccgggaa atataatgca acatgtcaac aggtactgga aaaacaaaca tttgtcacct
961 aaacggctga gcacaggtat tcttatgtac acccttgcat cagcaatatg tgaagagatc
1021 cacttgtatg gattttggcc gtttggattt gaccccaaca caagggaaga tcttccatac
1081 cattactatg acaaaaaagg aaccaaattt accaccaagt ggcaggagtc ccaccagctg
1141 cctgctgagt ttcagctgct gtaccgaatg catggggaag ggctcaccaa gctgactctg
1201 tcacactgtg cctaagaact ccaaacggaa agcgccaaat ggctgttt
//