LOCUS AF002697 1535 bp mRNA linear HUM 20-MAY-1998
DEFINITION Homo sapiens E1B 19K/Bcl-2-binding protein Nip3 mRNA, nuclear gene
encoding mitochondrial protein, complete cds.
ACCESSION AF002697
VERSION AF002697.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1535)
AUTHORS Chen,G., Ray,R., Dubik,D., Shi,L., Cizeau,J., Bleackley,R.C.,
Saxena,S., Gietz,R.D. and Greenberg,A.H.
TITLE The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial
protein that activates apoptosis
JOURNAL J. Exp. Med. 186 (12), 1975-1983 (1997)
PUBMED 9396766
REFERENCE 2 (bases 1 to 1535)
AUTHORS Chen,G., Shi,L., Ray,R., Dubik,D., Bleackley,C., Gietz,R.D. and
Greenberg,A.H.
TITLE Direct Submission
JOURNAL Submitted (06-MAY-1997) Cell Biology, University of Manitoba, 100
Olivia St., Winnipeg, MB R3E 0V9, Canada
FEATURES Location/Qualifiers
source 1..1535
/db_xref="H-InvDB:HIT000061689"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="B cell"
CDS 127..711
/note="pro-apoptotic mitochondrial protein"
/codon_start=1
/product="E1B 19K/Bcl-2-binding protein Nip3"
/protein_id="AAC16738.1"
/translation="MSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPASVSIYNGDME
KILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIER
RKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSAE
FLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF"
misc_feature 616..678
/note="encodes transmembrane domain"
BASE COUNT 454 a 324 c 323 g 434 t
ORIGIN
1 cctccgctca gtccgggagc gcacgtgggc cgcggcgctc cgacctccgc tttcccaccg
61 cccgcagctg aagcacatcc cgcagcccgg cgcggactcc gatcgccgca gttgccctct
121 ggcgccatgt cgcagaacgg agcgcccggg atgcaggagg agagcctgca gggctcctgg
181 gtagaactgc acttcagcaa taatgggaac gggggcagcg ttccagcctc ggtttctatt
241 tataatggag acatggaaaa aatactgctg gacgcacagc atgagtctgg acggagtagc
301 tccaagagct ctcactgtga cagcccacct cgctcgcaga caccacaaga taccaacagg
361 gcttctgaaa cagataccca tagcattgga gagaaaaaca gctcacagtc tgaggaagat
421 gatattgaaa gaaggaaaga agttgaaagc atcttgaaga aaaactcaga ttggatatgg
481 gattggtcaa gtcggccgga aaatattccc cccaaggagt tcctctttaa acacccgaag
541 cgcacggcca ccctcagcat gaggaacacg agcgtcatga agaaaggggg catattctct
601 gcagaatttc tgaaagtttt ccttccatct ctgctgctct ctcatttgct ggccatcgga
661 ttggggatct atattggaag gcgtctgaca acctccacca gcaccttttg atgaagaact
721 ggagtctgac ttggttcgtt agtggattac ttctgagctt gcaacatagc tcactgaaga
781 gctgttagat cctggggtgg ccacgtcact tgtgtttatt tgttctgtaa atgctgcgtt
841 cctaatttag taaaataaaa gaatagacac taaaatcatg ttgatctata attacaccta
901 tgggatcaat aagcatgtca gactgattaa tgtctactgt gaaaatttgg tagtaaattt
961 tcatttgata ttagatataa atatctgaat ataaataatt ttaatatact agtcatgatg
1021 tgtgttgtat tttaaaaatt atctgcaacc ttaattcagc tgaagtactt tatatttcaa
1081 aagaatgaat aacattgata ataaaatcgc tactttaagg ggtttgtcca aaataaatat
1141 tgtggcctta tatatcacac tattgtagaa agtattattt aatttaaatg gatgcaggtt
1201 gtctactaaa gaaagattat atataactat gctaattgtt cataatcaac agaaaccaag
1261 atagagctac aaactcagct gtacagttcg tacactaaac tcttcttgct tttgcattat
1321 aaggaattaa gtctccgatt attaggtgat caccctggat gatcagtttt ctgctgaagg
1381 cacctactca gtatcttttc ctctttatca ctctgcattg gtgaatttaa tcctctcctt
1441 tgtgttcaac ttttgtgtgc ttttaaaatc agctttattc taagcaaatc tgtgtctact
1501 ttaaaaaact ggaaatggaa aaaaaaataa atctt
//