LOCUS AF000574 1966 bp mRNA linear HUM 04-DEC-1997
DEFINITION Homo sapiens clone 1 immunoglobulin-like transcript 4 mRNA,
complete cds.
ACCESSION AF000574
VERSION AF000574.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1966)
AUTHORS Samaridis,J. and Colonna,M.
TITLE Cloning of novel immunoglobulin superfamily receptors expressed on
human myeloid and lymphoid cells: structural evidence for new
stimulatory and inhibitory pathways
JOURNAL Eur. J. Immunol. 27 (3), 660-665 (1997)
PUBMED 9079806
REFERENCE 2 (bases 1 to 1966)
AUTHORS Cella,M., Dohring,C., Samaridis,J., Dessing,M., Brockhaus,M.,
Lanzavecchia,A. and Colonna,M.
TITLE A novel inhibitory receptor (ILT3) expressed on monocytes,
macrophages, and dendritic cells involved in antigen processing
JOURNAL J. Exp. Med. 185 (10), 1743-1751 (1997)
PUBMED 9151699
REFERENCE 3 (bases 1 to 1966)
AUTHORS Colonna,M.
TITLE Direct Submission
JOURNAL Submitted (21-APR-1997) Basel Institute for Immunology, 487
Grenzacherstrasse, Basel CH-4005, Switzerland
FEATURES Location/Qualifiers
source 1..1966
/db_xref="H-InvDB:HIT000061587"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.4"
/clone="1"
/cell_type="myeloid antigen presenting cells"
CDS 1..1797
/note="immunoglobulin superfamily; inhibitory receptor
expressed by myeloid antigen presenting cells; ILT4"
/codon_start=1
/product="immunoglobulin-like transcript 4"
/protein_id="AAB88119.1"
/translation="MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSP
VTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYS
RARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGE
DEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLV
PGVSKKPSLSVQPGPVMAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGL
SQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPT
VASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAG
TYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSD
PQSGLGRHLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAV
GPEPTDRGLQWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLH
SLTLRRKATEPPPSQEREPPAEPSIYATLAIH"
BASE COUNT 415 a 659 c 523 g 369 t
ORIGIN
1 atgaccccca tcgtcacagt cctgatctgt ctcgggctga gtctgggccc caggacccac
61 gtgcagacag ggaccatccc caagcccacc ctgtgggctg agccagactc tgtgatcacc
121 caggggagtc ccgtcaccct cagttgtcag gggagccttg aagcccagga gtaccgtcta
181 tatagggaga aaaaatcagc atcttggatt acacggatac gaccagagct tgtgaagaac
241 ggccagttcc acatcccatc catcacctgg gaacacacag ggcgatatgg ctgtcagtat
301 tacagccgcg ctcggtggtc tgagctcagt gaccccctgg tgctggtgat gacaggagcc
361 tacccaaaac ccaccctctc agcccagccc agccctgtgg tgacctcagg aggaagggtg
421 accctccagt gtgagtcaca ggtggcattt ggcggcttca ttctgtgtaa ggaaggagaa
481 gatgaacacc cacaatgcct gaactcccag ccccatgccc gtgggtcgtc ccgcgccatc
541 ttctccgtgg gccccgtgag cccgaatcgc aggtggtcgc acaggtgcta tggttatgac
601 ttgaactctc cctatgtgtg gtcttcaccc agtgatctcc tggagctcct ggtcccaggt
661 gtttctaaga agccatcact ctcagtgcag ccgggtcctg tcatggcccc tggggaaagc
721 ctgaccctcc agtgtgtctc tgatgtcggc tatgacagat ttgttctgta caaggagggg
781 gaacgtgacc ttcgccagct ccctggccgg cagccccagg ctgggctctc ccaggccaac
841 ttcaccctgg gccctgtgag ccgctcctac gggggccagt acagatgcta cggtgcacac
901 aacctctcct ctgagtgctc ggcccccagc gaccccctgg acatcctgat cacaggacag
961 atccgtggca cacccttcat ctcagtgcag ccaggcccca cagtggcctc aggagagaac
1021 gtgaccctgc tgtgtcagtc atggcggcag ttccacactt tccttctgac caaggcggga
1081 gcagctgatg ccccactccg tctaagatca atacacgaat atcctaagta ccaggctgaa
1141 ttccccatga gtcctgtgac ctcagcccac gcggggacct acaggtgcta cggctcactc
1201 aactccgacc cctacctgct gtctcacccc agtgagcccc tggagctcgt ggtctcagga
1261 ccctccatgg gttccagccc cccacccacc ggtcccatct ccacacctgc aggccctgag
1321 gaccagcccc tcacccccac tgggtcggat ccccaaagtg gtctgggaag gcacctgggg
1381 gttgtgatcg gcatcttggt ggccgtcgtc ctactgctcc tcctcctcct cctcctcttc
1441 ctcatcctcc gacatcgacg tcagggcaaa cactggacat cgacccagag aaaggctgat
1501 ttccaacatc ctgcaggggc tgtggggcca gagcccacag acagaggcct gcagtggagg
1561 tccagcccag ctgccgacgc ccaggaagaa aacctctatg ctgccgtgaa ggacacacag
1621 cctgaagatg gggtggagat ggacactcgg gctgctgcat ctgaagcccc ccaggatgtg
1681 acctacgccc agctgcacag cttgaccctc agacggaagg caactgagcc tcctccatcc
1741 caggaaaggg aacctccagc tgagcccagc atctacgcca ccctggccat ccactagccc
1801 ggagggtacg cagactccac actcagtaga aggagactca ggactgctga aggcacggga
1861 gctgccccca gtggacacca atgaacccca gtcagcctgg acccctaaca aagaccatga
1921 ggagatgctg ggaactttgg gactcacttg attctgcagt cgaaat
//