LOCUS AB775900 1625 bp mRNA linear HUM 12-JAN-2013
DEFINITION Homo sapiens TYR mRNA for tyrosinase, complete cds, cell_line:
HM3KO.
ACCESSION AB775900
VERSION AB775900.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1625)
AUTHORS Sonoki,T. and Mikami,M.
TITLE Direct Submission
JOURNAL Submitted (09-JAN-2013) to the DDBJ/EMBL/GenBank databases.
Contact:Tomonori Sonoki
Hirosaki University, Faculty of Agriculture and Life Science; 3
Bunkyo, Hirosaki, Aomori 036-8561, Japan
REFERENCE 2
AUTHORS Mikami,M., Ito,M., Funasawa,Y., Suzuki,T., Sonoki,T. and
Katagata,Y.
TITLE Glycosylation of tyrosinase is one of the determinants of melanin
production by melanomas
JOURNAL Unpublished (2013)
COMMENT
FEATURES Location/Qualifiers
source 1..1625
/cell_line="HM3KO"
/cell_type="melanoma"
/db_xref="H-InvDB:HIT000660567"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 1..1590
/codon_start=1
/EC_number="1.14.18.1"
/gene="TYR"
/product="tyrosinase"
/protein_id="BAM75357.1"
/transl_table=1
/translation="MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRS
PCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGN
CKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMK
NGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRW
EQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVC
SRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDK
AANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAF
VDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYS
YLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLP
EEKQPLLMEKEDYHSLYQSHL"
BASE COUNT 423 a 393 c 381 g 428 t
ORIGIN
1 atgctcctgg ctgttttgta ctgcctgctg tggagtttcc agacctccgc tggccatttc
61 cctagagcct gtgtctcctc taagaacctg atggagaagg aatgctgtcc accgtggagc
121 ggggacagga gtccctgtgg ccagctttca ggcagaggtt cctgtcagaa tatccttctg
181 tccaatgcac cacttgggcc tcaatttccc ttcacagggg tggatgaccg ggagtcgtgg
241 ccttccgtct tttataatag gacctgccag tgctctggca acttcatggg attcaactgt
301 ggaaactgca agtttggctt ttggggacca aactgcacag agagacgact cttggtgaga
361 agaaacatct tcgatttgag tgccccagag aaggacaaat tttttgccta cctcacttta
421 gcaaagcata ccatcagctc agactatgtc atccccatag ggacctatgg ccaaatgaaa
481 aatggatcaa cacccatgtt taacgacatc aatatttatg acctctttgt ctggatgcat
541 tattatgtgt caatggatgc actgcttggg ggatctgaaa tctggagaga cattgatttt
601 gcccatgaag caccagcttt tctgccttgg catagactct tcttgttgcg gtgggaacaa
661 gaaatccaga agctgacagg agatgaaaac ttcactattc catattggga ctggcgggat
721 gcagaaaagt gtgacatttg cacagatgag tacatgggag gtcagcaccc cacaaatcct
781 aacttactca gcccagcatc attcttctcc tcttggcaga ttgtctgtag ccgattggag
841 gagtacaaca gccatcagtc tttatgcaat ggaacgcccg agggaccttt acggcgtaat
901 cctggaaacc atgacaaatc cagaacccca aggctcccct cttcagctga tgtagaattt
961 tgcctgagtt tgacccaata tgaatctggt tccatggata aagctgccaa tttcagcttt
1021 agaaatacac tggaaggatt tgctagtcca cttactggga tagcggatgc ctctcaaagc
1081 agcatgcaca atgccttgca catctatatg aatggaacaa tgtcccaggt acagggatct
1141 gccaacgatc ctatcttcct tcttcaccat gcatttgttg acagtatttt tgagcagtgg
1201 ctccgaaggc accgtcctct tcaagaagtt tatccagaag ccaatgcacc cattggacat
1261 aaccgggaat cctacatggt tccttttata ccactgtaca gaaatggtga tttctttatt
1321 tcatccaaag atctgggcta tgactatagc tatctacaag attcagaccc agactctttt
1381 caagactaca ttaagtccta tttggaacaa gcgagtcgga tctggtcatg gctccttggg
1441 gcggcgatgg taggggccgt cctcactgcc ctgctggcag ggcttgtgag cttgctgtgt
1501 cgtcacaaga gaaagcagct tcctgaagaa aagcagccac tcctcatgga gaaagaggat
1561 taccacagct tgtatcagag ccatttataa aaggcttagg caatagagta gggccaaaaa
1621 gcctg
//