LOCUS AB500182 2506 bp mRNA linear HUM 10-NOV-2009
DEFINITION Homo sapiens HIF1A mRNA for hypoxia-inducible factor 1, alpha
subunit, variant K12NR, complete cds.
ACCESSION AB500182
VERSION AB500182.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2506)
AUTHORS Tanahashi,H.
TITLE Direct Submission
JOURNAL Submitted (08-MAY-2009) to the DDBJ/EMBL/GenBank databases.
Contact:Hiroshi Tanahashi
Shinshu University Graduate School of Medicine, Department of
Neuroplasticity; 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
E-mail :tanahasi@shinshu-u.ac.jp
Phone :81-263-37-2727
Fax :81-263-37-2725
REFERENCE 2
AUTHORS Tanahashi,H.
TITLE A novel HIF1A transcript (K12NR) produced by the use of an
alternative-splicing acceptor site in intron 1.
JOURNAL Unpublished (2009)
COMMENT
FEATURES Location/Qualifiers
source 1..2506
/chromosome="14"
/db_xref="H-InvDB:HIT000563756"
/db_xref="taxon:9606"
/map="14q21-q24"
/mol_type="mRNA"
/note="This transcript has c957T>C polymorphism."
/organism="Homo sapiens"
/tissue_type="kidney"
CDS 26..2506
/codon_start=1
/gene="HIF1A"
/gene_synonym="HIF1"
/product="hypoxia-inducible factor 1, alpha subunit,
variant K12NR"
/protein_id="BAI49183.1"
/transl_table=1
/translation="MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQL
PLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMV
LTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKE
QNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMT
CLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIY
EYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQC
IVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKK
EPDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSPNEKLQNINLAM
SPLPTAETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQTPSPSDGSTRQ
SSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYI
PMDDDFQLRSFDQLSPLESSSASPESASPQSTVTVFQQTQIQEPTANATTTTATTDEL
KTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYRDTQSRTASPNRAGKGVIEQTEK
SHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKRKMEHDGSLFQAVGIGTLLQQ
PDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSY
DCEVNAPIQGSRNLLQGEELLRALDQVN"
BASE COUNT 836 a 521 c 507 g 642 t
ORIGIN
1 aagacatcgc ggggaccgat tcaccatgga gggcgccggc ggcgcgaacg acaagaaaaa
61 gataagttct gaacgtcgaa aagaaaagtc tcgagatgca gccagatctc ggcgaagtaa
121 agaatctgaa gttttttatg agcttgctca tcagttgcca cttccacata atgtgagttc
181 gcatcttgat aaggcctctg tgatgaggct taccatcagc tatttgcgtg tgaggaaact
241 tctggatgct ggtgatttgg atattgaaga tgacatgaaa gcacagatga attgctttta
301 tttgaaagcc ttggatggtt ttgttatggt tctcacagat gatggtgaca tgatttacat
361 ttctgataat gtgaacaaat acatgggatt aactcagttt gaactaactg gacacagtgt
421 gtttgatttt actcatccat gtgaccatga ggaaatgaga gaaatgctta cacacagaaa
481 tggccttgtg aaaaagggta aagaacaaaa cacacagcga agcttttttc tcagaatgaa
541 gtgtacccta actagccgag gaagaactat gaacataaag tctgcaacat ggaaggtatt
601 gcactgcaca ggccacattc acgtatatga taccaacagt aaccaacctc agtgtgggta
661 taagaaacca cctatgacct gcttggtgct gatttgtgaa cccattcctc acccatcaaa
721 tattgaaatt cctttagata gcaagacttt cctcagtcga cacagcctgg atatgaaatt
781 ttcttattgt gatgaaagaa ttaccgaatt gatgggatat gagccagaag aacttttagg
841 ccgctcaatt tatgaatatt atcatgcttt ggactctgat catctgacca aaactcatca
901 tgatatgttt actaaaggac aagtcaccac aggacagtac aggatgcttg ccaaaagagg
961 tggatatgtc tgggttgaaa cccaagcaac tgtcatatat aacaccaaga attctcaacc
1021 acagtgcatt gtatgtgtga attacgttgt gagtggtatt attcagcacg acttgatttt
1081 ctcccttcaa caaacagaat gtgtccttaa accggttgaa tcttcagata tgaaaatgac
1141 tcagctattc accaaagttg aatcagaaga tacaagtagc ctctttgaca aacttaagaa
1201 ggaacctgat gctttaactt tgctggcccc agccgctgga gacacaatca tatctttaga
1261 ttttggcagc aacgacacag aaactgatga ccagcaactt gaggaagtac cattatataa
1321 tgatgtaatg ctcccctcac ccaacgaaaa attacagaat ataaatttgg caatgtctcc
1381 attacccacc gctgaaacgc caaagccact tcgaagtagt gctgaccctg cactcaatca
1441 agaagttgca ttaaaattag aaccaaatcc agagtcactg gaactttctt ttaccatgcc
1501 ccagattcag gatcagacac ctagtccttc cgatggaagc actagacaaa gttcacctga
1561 gcctaatagt cccagtgaat attgttttta tgtggatagt gatatggtca atgaattcaa
1621 gttggaattg gtagaaaaac tttttgctga agacacagaa gcaaagaacc cattttctac
1681 tcaggacaca gatttagact tggagatgtt agctccctat atcccaatgg atgatgactt
1741 ccagttacgt tccttcgatc agttgtcacc attagaaagc agttccgcaa gccctgaaag
1801 cgcaagtcct caaagcacag ttacagtatt ccagcagact caaatacaag aacctactgc
1861 taatgccacc actaccactg ccaccactga tgaattaaaa acagtgacaa aagaccgtat
1921 ggaagacatt aaaatattga ttgcatctcc atctcctacc cacatacata aagaaactac
1981 tagtgccaca tcatcaccat atagagatac tcaaagtcgg acagcctcac caaacagagc
2041 aggaaaagga gtcatagaac agacagaaaa atctcatcca agaagcccta acgtgttatc
2101 tgtcgctttg agtcaaagaa ctacagttcc tgaggaagaa ctaaatccaa agatactagc
2161 tttgcagaat gctcagagaa agcgaaaaat ggaacatgat ggttcacttt ttcaagcagt
2221 aggaattgga acattattac agcagccaga cgatcatgca gctactacat cactttcttg
2281 gaaacgtgta aaaggatgca aatctagtga acagaatgga atggagcaaa agacaattat
2341 tttaataccc tctgatttag catgtagact gctggggcaa tcaatggatg aaagtggatt
2401 accacagctg accagttatg attgtgaagt taatgctcct atacaaggca gcagaaacct
2461 actgcagggt gaagaattac tcagagcttt ggatcaagtt aactga
//