LOCUS AB445638 2520 bp mRNA linear HUM 05-DEC-2008
DEFINITION Homo sapiens TLR4 mRNA for toll-like receptor 4, complete cds.
ACCESSION AB445638
VERSION AB445638.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2520)
AUTHORS Nakajima,T., Ohtani,H., Satta,Y., Uno,Y., Akari,H., Ishida,T. and
Kimura,A.
TITLE Direct Submission
JOURNAL Submitted (09-JUL-2008) to the DDBJ/EMBL/GenBank databases.
Contact:Toshiaki Nakajima
Tokyo Medical and Dental University, Medical Research Institute;
2-3-10 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan
REFERENCE 2
AUTHORS Nakajima,T., Ohtani,H., Satta,Y., Uno,Y., Akari,H., Ishida,T. and
Kimura,A.
TITLE Natural selection in the TLR-related genes in the course of
primate evolution
JOURNAL Immunogenetics 60, 727-735 (2008)
COMMENT
FEATURES Location/Qualifiers
source 1..2520
/db_xref="H-InvDB:HIT000487374"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 1..2520
/codon_start=1
/gene="TLR4"
/product="toll-like receptor 4"
/protein_id="BAG55035.1"
/transl_table=1
/translation="MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELN
FYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLS
HLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHN
LIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFI
QPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSA
LEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQH
LELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCS
QSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLI
YLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQL
EQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQH
FPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLN
ITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSS
QDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQH
FIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWE
DSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI"
BASE COUNT 692 a 551 c 529 g 748 t
ORIGIN
1 atgatgtctg cctcgcgcct ggctgggact ctgatcccag ccatggcctt cctctcctgc
61 gtgagaccag aaagctggga gccctgcgtg gaggtggttc ctaatattac ttatcaatgc
121 atggagctga atttctacaa aatccccgac aacctcccct tctcaaccaa gaacctggac
181 ctgagcttta atcccctgag gcatttaggc agctatagct tcttcagttt cccagaactg
241 caggtgctgg atttatccag gtgtgaaatc cagacaattg aagatggggc atatcagagc
301 ctaagccacc tctctacctt aatattgaca ggaaacccca tccagagttt agccctggga
361 gccttttctg gactatcaag tttacagaag ctggtggctg tggagacaaa tctagcatct
421 ctagagaact tccccattgg acatctcaaa actttgaaag aacttaatgt ggctcacaat
481 cttatccaat ctttcaaatt acctgagtat ttttctaatc tgaccaatct agagcacttg
541 gacctttcca gcaacaagat tcaaagtatt tattgcacag acttgcgggt tctacatcaa
601 atgcccctac tcaatctctc tttagacctg tccctgaacc ctatgaactt tatccaacca
661 ggtgcattta aagaaattag gcttcataag ctgactttaa gaaataattt tgatagttta
721 aatgtaatga aaacttgtat tcaaggtctg gctggtttag aagtccatcg tttggttctg
781 ggagaattta gaaatgaagg aaacttggaa aagtttgaca aatctgctct agagggcctg
841 tgcaatttga ccattgaaga attccgatta gcatacttag actactacct cgatgatatt
901 attgacttat ttaattgttt gacaaatgtt tcttcatttt ccctggtgag tgtgactatt
961 gaaagggtaa aagacttttc ttataatttc ggatggcaac atttagaatt agttaactgt
1021 aaatttggac agtttcccac attgaaactc aaatctctca aaaggcttac tttcacttcc
1081 aacaaaggtg ggaatgcttt ttcagaagtt gatctaccaa gccttgagtt tctagatctc
1141 agtagaaatg gcttgagttt caaaggttgc tgttctcaaa gtgattttgg gacaaccagc
1201 ctaaagtatt tagatctgag cttcaatggt gttattacca tgagttcaaa cttcttgggc
1261 ttagaacaac tagaacatct ggatttccag cattccaatt tgaaacaaat gagtgagttt
1321 tcagtattcc tatcactcag aaacctcatt taccttgaca tttctcatac tcacaccaga
1381 gttgctttca atggcatctt caatggcttg tccagtctcg aagtcttgaa aatggctggc
1441 aattctttcc aggaaaactt ccttccagat atcttcacag agctgagaaa cttgaccttc
1501 ctggacctct ctcagtgtca actggagcag ttgtctccaa cagcatttaa ctcactctcc
1561 agtcttcagg tactaaatat gagccacaac aacttctttt cattggatac gtttccttat
1621 aagtgtctga actccctcca ggttcttgat tacagtctca atcacataat gacttccaaa
1681 aaacaggaac tacagcattt tccaagtagt ctagctttct taaatcttac tcagaatgac
1741 tttgcttgta cttgtgaaca ccagagtttc ctgcaatgga tcaaggacca gaggcagctc
1801 ttggtggaag ttgaacgaat ggaatgtgca acaccttcag ataagcaggg catgcctgtg
1861 ctgagtttga atatcacctg tcagatgaat aagaccatca ttggtgtgtc ggtcctcagt
1921 gtgcttgtag tatctgttgt agcagttctg gtctataagt tctattttca cctgatgctt
1981 cttgctggct gcataaagta tggtagaggt gaaaacatct atgatgcctt tgttatctac
2041 tcaagccagg atgaggactg ggtaaggaat gagctagtaa agaatttaga agaaggggtg
2101 cctccatttc agctctgcct tcactacaga gactttattc ccggtgtggc cattgctgcc
2161 aacatcatcc atgaaggttt ccataaaagc cgaaaggtga ttgttgtggt gtcccagcac
2221 ttcatccaga gccgctggtg tatctttgaa tatgagattg ctcagacctg gcagtttctg
2281 agcagtcgtg ctggtatcat cttcattgtc ctgcagaagg tggagaagac cctgctcagg
2341 cagcaggtgg agctgtaccg ccttctcagc aggaacactt acctggagtg ggaggacagt
2401 gtcctggggc ggcacatctt ctggagacga ctcagaaaag ccctgctgga tggtaaatca
2461 tggaatccag aaggaacagt gggtacagga tgcaattggc aggaagcaac atctatctga
//