LOCUS AB257295 2423 bp mRNA linear HUM 31-MAY-2006
DEFINITION Homo sapiens RECS1 mRNA for responsive to centrifugal force and
shear stress gene 1, complete cds.
ACCESSION AB257295
VERSION AB257295.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2423)
AUTHORS Nojima,H. and Zhao,H.
TITLE Direct Submission
JOURNAL Submitted (14-APR-2006) to the DDBJ/EMBL/GenBank databases.
Contact:Hiroshi Nojima
Research Institute for Microbial Diseases, Osaka University,
Department of Molecular Genetics; 3-1 Yamadaoka, Suita City, Osaka
565-0871, Japan
REFERENCE 2
AUTHORS Zhao,H., Ito,A., Kimura,S., Yabuta,N., Sakai,N., Ikawa,M.,
Okabe,M., Matsuzawa,Y., Yamashita,Y. and Nojima,H.
TITLE RECS1 deficiency in mice induces susceptibility to cystic medial
degeneration.
JOURNAL Genes Genet. Syst. 81, 41-50 (2006)
REFERENCE 3
AUTHORS Zhao,H., Ito,A., Sakai,N., Matsuzawa,Y., Yamashita,Y. and Nojima,H.
TITLE RECS1 is a negative regulator of MMP-9 production and aged RECS1
knockout mice are prone to aortic dilation.
JOURNAL Circ. J. 70, 615-624 (2006)
REFERENCE 4
AUTHORS Yoshisue,H., Suzuki,K., Kawabata,A., Ohya,T., Zhao,H.,
Sakurada,K., Taba,Y., Sasaguri,T., Sakai,N., Yamashita,S.,
Matsuzawa,Y. and Nojima,H.
TITLE Large scale isolation of non-uniform shear stress-responsive genes
from cultured human endothelial cells through the preparation of a
subtracted cDNA library.
JOURNAL Atherosclerosis 162, 323-334 (2002)
REFERENCE 5
AUTHORS Hwang,K.C., Cui,X.S., Park,S.P., Shin,M.R., Park,S.Y., Kim,E.Y.
and Kim,N.H.
TITLE Identification of differentially regulated genes in bovine
blastocysts using an annealing control primer system
JOURNAL Mol. Reprod. Dev. 69, 43-51 (2004)
COMMENT
FEATURES Location/Qualifiers
source 1..2423
/chromosome="2"
/country="Japan"
/db_xref="H-InvDB:HIT000330053"
/db_xref="taxon:9606"
/isolation_source="cultured human umbilical vein
endothelial cells"
/map="2p24.3-p24.1"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 214..1149
/codon_start=1
/function="mechanical stress responsive"
/gene="RECS1"
/note="RECS1 (responsive to centrifugal force and shear
stress gene 1)"
/product="responsive to centrifugal force and shear
stress gene 1"
/protein_id="BAE93467.1"
/transl_table=1
/translation="MSNPSAPPPYEDRNPLYPGPLPPGGYGQPSVLPGGYPAYPGYPQ
PGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKV
YSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRR
FPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTS
CTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNR
KHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN"
BASE COUNT 515 a 663 c 633 g 612 t
ORIGIN
1 atgccagccc caaacctcat ccctagtgga ggccttgctg atgtggaagt ggccagggcc
61 ctcatggtag gctgggcaga agcccaagaa caggctctaa agctgctaaa cccggcagtc
121 ctggtccccg gaggctcttg ccagtctgac agtgttcttg gcactgctca aaggtcccag
181 cagctggggt tccccgtcag cccgtgagcg gccatgtcca accccagcgc cccaccacca
241 tatgaagacc gcaaccccct gtacccaggc cctctgcccc ctgggggcta tgggcagcca
301 tctgtcctgc caggagggta tcctgcctac cctggctacc cgcagcctgg ctacggtcac
361 cctgctggct acccacagcc catgcccccc acccacccga tgcccatgaa ctacggccca
421 ggccatggct atgatgggga ggagagagcg gtgagtgata gcttcgggcc tggagagtgg
481 gatgaccgga aagtgcgaca cacttttatc cgaaaggttt actccatcat ctccgtgcag
541 ctgctcatca ctgtggccat cattgctatc ttcacctttg tggaacctgt cagcgccttt
601 gtgaggagaa atgtggctgt ctactacgtg tcctatgctg tcttcgttgt cacctacctg
661 atccttgcct gctgccaggg acccagacgc cgtttcccat ggaacatcat tctgctgacc
721 ctttttactt ttgccatggg cttcatgacg ggcaccattt ccagtatgta ccaaaccaaa
781 gccgtcatca ttgcaatgat catcactgcg gtggtatcca tttcagtcac catcttctgc
841 tttcagacca aggtggactt cacctcgtgc acaggcctct tctgtgtcct gggaattgtg
901 ctcctggtga ctgggattgt cactagcatt gtgctctact tccaatacgt ttactggctc
961 cacatgctct atgctgctct gggggccatt tgtttcaccc tgttcctggc ttacgacaca
1021 cagctggtcc tggggaaccg gaagcacacc atcagccccg aggactacat cactggcgcc
1081 ctgcagattt acacagacat catctacatc ttcacctttg tgctgcagct gatgggggat
1141 cgcaattaag gagcaagccc ccattttcac ccgatcctgg gctctccctt ccaagctaga
1201 gggctgggcc ctatgactgt ggtctgggct ttaggcccct ttccttcccc ttgagtaaca
1261 tgcccagttt cctttctgtc ctggagacag gtggcctctc tggctatgga tgtgtgggta
1321 cttggtgggg acggaggagc tagggactaa ctgttgctct tggtgggctt ggcagggact
1381 aggctgaaga tgtgtcttct ccccgccacc tactgtatga caccacattc ttcctaacag
1441 ctggggttgt gaggaatatg aaaagagcct attcgatagc tagaagggaa tatgaaaggt
1501 agaagtgact tcaaggtcac gaggttcccc tcccacctct gtcacaggct tcttgactac
1561 gtagttggag ctatttcttc ccccagcaaa gccagagagc tttgtccccg gcctcctgga
1621 cacataggcc attatcctgt attcctttgg cttggcatct tttagctcag gaaggtagaa
1681 gagatctgtg cccatgggtc tccttgcttc aatcccttct tgtttcagtg acatatgtat
1741 tgtttatctg ggttagggat gggggacaga taatagaacg agcaaagtaa cctatacagg
1801 ccagcatgga acagcatctc ccctgggctt gctcctggct tgtgacgcta taagacagag
1861 caggccacat gtggccatct gctccccatt cttgaaagct gctggggcct ccttgcaggc
1921 ttctggatct ctggtcagag tgaactcttg cttcctgtat tcaggcagct cagagcagaa
1981 agtaaggggc agagtcatac gtgtggccag gaagtagcca gggtgaagag agactcggtg
2041 cgggcaggga gaatgcctgg gggtccctca cctggctagg gagataccga agcctactgt
2101 ggtactgaag acttctgggt tctttccttc tgctaaccca gggagggtcc taagaggaag
2161 gtgacttctc tctgtttgtc ttaagttgca ctgggggatt tctgacttga ggcccatctc
2221 tccagccagc cactgccttc tttgtaatat taagtgcctt gagctggaat ggggaagggg
2281 gacaagggtc agtctgtcgg gtgggggcag aaatcaaatc agcccaagga tatagttagg
2341 attaattact taatagagaa atcctaacta tatcacacaa agggatacaa ctataaatgt
2401 aataaaattt atgtctagaa gtt
//