LOCUS AB178028 1660 bp mRNA linear HUM 12-JAN-2005
DEFINITION Homo sapiens MTU1 mRNA for mitochondrial tRNA-specific
2-thiouridylase 1, complete cds.
ACCESSION AB178028
VERSION AB178028.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1660)
AUTHORS Umeda,N., Suzuki,T., Yukawa,M., Ohya,Y., Shindo,H., Watanabe,K.
and Suzuki,T.
TITLE Direct Submission
JOURNAL Submitted (23-APR-2004) to the DDBJ/EMBL/GenBank databases.
Contact:Noriko Umeda
University of Tokyo, Department of Integrated Bioscience; Bidg.
VP-302, 5-4-19 Kashiwanoha, Kashiwa, Chiba 277-0882, Japan
REFERENCE 2
AUTHORS Umeda,N., Suzuki,T., Yukawa,M., Ohya,Y., Shindo,H., Watanabe,K.
and Suzuki,T.
TITLE Mitochondria-specific RNA-modifying Enzymes Responsible for the
Biosynthesis of the Wobble Base in Mitochondrial tRNAs:
IMPLICATIONS FOR THE MOLECULAR PATHOGENESIS OF HUMAN MITOCHONDRIAL
DISEASES
JOURNAL J. Biol. Chem. 280, 1613-1624 (2005)
COMMENT
FEATURES Location/Qualifiers
source 1..1660
/chromosome="22q13"
/db_xref="H-InvDB:HIT000242510"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 52..1317
/codon_start=1
/gene="MTU1"
/product="mitochondrial tRNA-specific 2-thiouridylase 1"
/protein_id="BAD66875.1"
/transl_table=1
/translation="MQALRHVVCALSGGVDSAVAALLLRRRGYQVTGVFMKNWDSLDE
HGVCTADKDCEDAYRVCQILDIPFHQVSYVKEYWNDVFSDFLNEYEKGRTPNPDIVCN
KHIKFSCFFHYAVDNLGADAIATGHYARTSLEDEEVFEQKHVKKPEGLFRNRFEVRNA
VKLLQAADSFKDQTFFLSQVSQDALRRTIFPLGGLTKEFVKKIAAENRLHHVLQKKES
MGMCFIGKRNFEHFLLQYLQPRPGHFISIEDNKVLGTHKGWFLYTLGQRANIGGLREP
WYVVEKDSVKGDVFVAPRTDHPALYRDLLRTSRVHWIAEEPPAALVRDKMMECHFRFR
HQMALVPCVLTLNQDGTVWVTAVQAVRALATGQFAVFYKGDECLGSGKILRLGPSAYT
LQKGQRRAGMATESPSDSPEDGPGLSPLL"
BASE COUNT 388 a 408 c 517 g 347 t
ORIGIN
1 aaggcgcgga agcggcggta gctgcagctg gcgaagttgg gcgactggcg gatgcaggcc
61 ttgcggcacg tcgtgtgcgc cctgtccggc ggcgtggaca gcgccgtggc cgcgctgctg
121 ctgaggcgga gaggttacca ggtgacaggg gtgtttatga agaactggga ctcactggat
181 gaacatgggg tctgtactgc cgacaaagac tgtgaagatg cttacagagt ttgccagatc
241 ttagacatcc ctttccatca agtgtcctac gtaaaggagt attggaatga tgtgttcagt
301 gactttttga atgagtatga aaaaggaagg actcccaatc ctgacatagt ttgcaacaag
361 cacatcaaat ttagttgctt ttttcattat gctgtggata atcttggggc agatgccatt
421 gccacaggtc actatgcaag aacttccctg gaagatgaag aagtctttga gcagaagcac
481 gttaagaagc ccgaagggct tttcagaaat cggtttgaag ttagaaatgc ggtaaaactc
541 ctccaggcag ctgacagctt taaagaccag accttctttc tcagccaggt ttcccaggat
601 gccctgagga gaaccatctt ccctctgggg ggattaacga aagagtttgt aaagaaaatc
661 gctgctgaga atagacttca tcatgtgctt cagaagaaag agagcatggg catgtgtttc
721 atcgggaaga ggaattttga acatttcctt cttcagtatc tgcagcctcg acctggtcac
781 tttatttcca tagaagacaa taaggttctg ggaacacata aaggttggtt cctgtatacc
841 ttgggccaga gagcaaacat aggtggcctg agagagccct ggtacgtggt ggagaaggac
901 agcgtcaagg gtgacgtgtt tgtggccccc cggacagacc acccagccct gtacagggac
961 ctgctgagga ccagccgcgt gcactggatt gcggaggagc ctcccgcagc actggtccgg
1021 gacaagatga tggagtgcca cttccgattc cgccaccaga tggcactagt gccctgtgtg
1081 ctgaccctca atcaagatgg caccgtgtgg gtgacagctg tgcaggctgt gcgtgccctt
1141 gccacaggac agtttgctgt gttctacaag ggggacgagt gcctgggcag cgggaagatc
1201 ctgcggctgg ggccgtctgc ctacacgctc cagaagggcc agcgcagagc tgggatggcc
1261 actgagagcc ccagtgacag cccagaagat ggtccaggcc tgagtccctt gctctgacag
1321 agatggatct gctagaagga acctggagag caggacccat ggctgggcgg ctggtgagca
1381 gtccaggtgc ccaagggcca gcttgctgct gcccaaagca gaggaagccg ggctggctga
1441 gggtccgaaa agcctgcagg ggcccggcga gccccaggaa gagcctcagc tccaggctgg
1501 ggctctggct gctggagcat ctgctggctg gtggggtggc ccgagttccc ttaccgccca
1561 gggagggttc ccactcaaag ttcccccggc acgcaagggg ctgtcggaca cttgaataac
1621 cttttcagga caaaaaaagg cggcgggtaa agttcccagg
//