LOCUS AB166745 5988 bp mRNA linear HUM 22-FEB-2005
DEFINITION Homo sapiens TRPM2 mRNA for transient receptor potential cation
channel, subfamily M, member 2, long form, complete cds.
ACCESSION AB166745
VERSION AB166745.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5988)
AUTHORS Shimizu,N., Uemura,T. and Kudoh,J.
TITLE Direct Submission
JOURNAL Submitted (04-MAR-2004) to the DDBJ/EMBL/GenBank databases.
Contact:Nobuyoshi Shimizu
Keio University School of Medicine, Molecular Biology; 35
Shinanomachi, Shinjuku-ku, Tokyo 160-582, Japan
REFERENCE 2
AUTHORS Uemura,T., Kudoh,J., Noda,S., Kanba,S. and Shimizu,N.
TITLE Characterization of human and mouse TRPM2 genes: Identification of
a novel N-terminal truncated protein specifically expressed in
human striatum
JOURNAL Biochem. Biophys. Res. Commun. 328, 1232-1243 (2005)
COMMENT
FEATURES Location/Qualifiers
source 1..5988
/chromosome="21"
/db_xref="H-InvDB:HIT000242479"
/db_xref="taxon:9606"
/map="21q22.3"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="brain"
CDS 214..4725
/codon_start=1
/gene="TRPM2"
/product="transient receptor potential cation channel,
subfamily M, member 2, long form (LF-TRPM2)"
/protein_id="BAD83705.1"
/translation="MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSW
RLQCPFGNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEA
TKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQ
HWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQV
GEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTC
LDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGP
GTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFE
TFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHE
NWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGV
QLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLR
ELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVTFTMDPIRD
LLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEY
EHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLT
KVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVV
FHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGL
MKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILSLDFILFCLRLMHIF
TISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVY
HSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLC
LYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLS
HLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQ
KIEDISNKVDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTARALHWIVRTLRASGFS
SEADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNEKV
PWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQ
AGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVK
LPLSEHWALPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTD
NAWIETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQK
AAAEFGAHY"
BASE COUNT 1191 a 1877 c 1837 g 1083 t
ORIGIN
1 tgcaccgggc acgcggcgca cgctcgggcg agatgtggat ggccccgcgg ggccagggcg
61 gcggtgctgc gcggggacgc gggtgacgcc ggggcgcggg cggctccgag cagcaaccac
121 cccatgtgtc tctagaaccc cagtgtagcg agctggagag aggactgtcc tgagggcagc
181 aggcctggtt gcagctggcg tgggggtctc agaatggagc cctcagccct gaggaaagct
241 ggctcggagc aggaggaggg ctttgagggg ctgcccagaa gggtcactga cctggggatg
301 gtctccaatc tccggcgcag caacagcagc ctcttcaaga gctggaggct acagtgcccc
361 ttcggcaaca atgacaagca agaaagcctc agttcgtgga ttcctgaaaa catcaagaag
421 aaagaatgcg tgtattttgt ggaaagttcc aaactgtctg atgctgggaa ggtggtgtgt
481 cagtgtggct acacgcatga gcagcacttg gaggaggcta ccaagcccca caccttccag
541 ggcacacagt gggacccaaa gaaacatgtc caggagatgc caaccgatgc ctttggcgac
601 atcgtcttca cgggcctgag ccagaaggtg aaaaagtacg tccgagtctc ccaggacacg
661 ccctccagcg tgatctacca cctcatgacc cagcactggg ggctggacgt ccccaatctc
721 ttgatctcgg tgaccggggg ggccaagaac ttcaacatga agccgcggct gaagagcatt
781 ttccgcagag gcctggtcaa ggtggctcag accacagggg cctggatcat cacagggggg
841 tcccacaccg gcgtcatgaa gcaggtaggc gaggcggtgc gggacttcag cctgagcagc
901 agctacaagg aaggcgagct catcaccatc ggagtcgcca cctggggcac tgtccaccgc
961 cgcgagggcc tgatccatcc cacgggcagc ttccccgccg agtacatact ggatgaggat
1021 ggccaaggga acctgacctg cctagacagc aaccactctc acttcatcct cgtggacgac
1081 gggacccacg gccagtacgg ggtggagatt cctctgagga ccaggctgga gaagttcata
1141 tcggagcaga ccaaggaaag aggaggtgtg gccatcaaga tccccatcgt gtgcgtggtg
1201 ctggagggcg gcccgggcac gttgcacacc atcgacaacg ccaccaccaa cggcaccccc
1261 tgtgtggttg tggagggctc gggccgcgtg gccgacgtca ttgcccaggt ggccaacctg
1321 cctgtctcgg acatcactat ctccctgatc cagcagaaac tgagcgtgtt cttccaggag
1381 atgtttgaga ccttcacgga aagcaggatt gtcgagtgga ccaaaaagat ccaagatatt
1441 gtccggaggc ggcagctgct gactgtcttc cgggaaggca aggatggtca gcaggacgtg
1501 gatgtggcca tcttgcaggc cttgctgaaa gcctcacgga gccaagacca ctttggccac
1561 gagaactggg accaccagct gaaactggca gtggcatgga atcgcgtgga cattgcccgc
1621 agtgagatct tcatggatga gtggcagtgg aagccttcag atctgcaccc cacgatgaca
1681 gctgcactca tctccaacaa gcctgagttt gtgaagctct tcctggaaaa cggggtgcag
1741 ctgaaggagt ttgtcacctg ggacaccttg ctctacctgt acgagaacct ggacccctcc
1801 tgcctgttcc acagcaagct gcaaaaggtg ctggtggagg atcccgagcg cccggcttgc
1861 gcgcccgcgg cgccccgcct gcagatgcac cacgtggccc aggtgctgcg ggagctgctg
1921 ggggacttca cgcagccgct ttatccccgg ccccggcaca acgaccggct gcggctcctg
1981 ctgcccgttc cccacgtcaa gctcaacgtg cagggagtga gcctccggtc cctctacaag
2041 cgttcctcag gccatgtgac cttcaccatg gaccccatcc gtgaccttct catttgggcc
2101 attgtccaga accgtcggga gctggcagga atcatctggg ctcagagcca ggactgcatc
2161 gcagcggcct tggcctgcag caagatcctg aaggaactgt ccaaggagga ggaggacacg
2221 gacagctcgg aggagatgct ggcgctggcg gaggagtatg agcacagagc catcggggtc
2281 ttcaccgagt gctaccggaa ggacgaagag agagcccaga aactgctcac ccgcgtgtcc
2341 gaggcctggg ggaagaccac ctgcctgcag ctcgccctgg aggccaagga catgaagttt
2401 gtgtctcacg ggggcatcca ggccttcctg accaaggtgt ggtggggcca gctctccgtg
2461 gacaatgggc tgtggcgtgt gaccctgtgc atgctggcct tcccgctgct cctcaccggc
2521 ctcatctcct tcagggagaa gaggctgcag gatgtgggca cccccgcggc ccgcgcccgt
2581 gccttcttca ccgcacccgt ggtggtcttc cacctgaaca tcctctccta cttcgccttc
2641 ctctgcctgt tcgcctacgt gctcatggtg gacttccagc ctgtgccctc ctggtgcgag
2701 tgtgccatct acctctggct cttctccttg gtgtgcgagg agatgcggca gctcttctat
2761 gaccctgacg agtgcgggct gatgaagaag gcagccttgt acttcagtga cttctggaat
2821 aagctggacg tcggcgcaat cttgctcttc gtggcagggc tgacctgcag gctcatcccg
2881 gcgacgctgt accccgggcg cgtcatcctc tctctggact tcatcctgtt ctgcctccgg
2941 ctcatgcaca tttttaccat cagtaagacg ctggggccca agatcatcat tgtgaagcgg
3001 atgatgaagg acgtcttctt cttcctcttc ctgctggctg tgtgggtggt gtccttcggg
3061 gtggccaagc aggccatcct catccacaac gagcgccggg tggactggct gttccgaggg
3121 gccgtctacc actcctacct caccatcttc gggcagatcc cgggctacat cgacggtgtg
3181 aacttcaacc cggagcactg cagccccaat ggcaccgacc cctacaagcc taagtgcccc
3241 gagagcgacg cgacgcagca gaggccggcc ttccctgagt ggctgacggt cctcctactc
3301 tgcctctacc tgctcttcac caacatcctg ctgctcaacc tcctcatcgc catgttcaac
3361 tacaccttcc agcaggtgca ggagcacacg gaccagattt ggaagttcca gcgccatgac
3421 ctgatcgagg agtaccacgg ccgccccgcc gcgccgcccc ccttcatcct cctcagccac
3481 ctgcagctct tcatcaagag ggtggtcctg aagactccgg ccaagaggca caagcagctc
3541 aagaacaagc tggagaagaa cgaggaggcg gccctgctat cctgggagat ctacctgaag
3601 gagaactacc tccagaaccg acagttccag caaaagcagc ggcccgagca gaagatcgag
3661 gacatcagca ataaggttga cgccatggtg gacctgctgg acctggaccc actgaagagg
3721 tcgggctcca tggagcagag gttggcctcc ctggaggagc aggtggccca gacagcccga
3781 gccctgcact ggatcgtgag gacgctgcgg gccagcggct tcagctcgga ggcggacgtc
3841 cccactctgg cctcccagaa ggccgcggag gagccggatg ctgagccggg aggcaggaag
3901 aagacggagg agccgggcga cagctaccac gtgaatgccc ggcacctcct ctaccccaac
3961 tgccctgtca cgcgcttccc cgtgcccaac gagaaggtgc cctgggagac ggagttcctg
4021 atctatgacc caccctttta cacggcagag aggaaggacg cggccgccat ggaccccatg
4081 ggagacaccc tggagccact gtccacgatc cagtacaacg tggtggatgg cctgagggac
4141 cgccggagct tccacgggcc gtacacagtg caggccgggt tgcccctgaa ccccatgggc
4201 cgcacaggac tgcgtgggcg cgggagcctc agctgcttcg gacccaacca cacgctgtac
4261 cccatggtca cgcggtggag gcggaacgag gatggagcca tctgcaggaa gagcataaag
4321 aagatgctgg aagtgctggt ggtgaagctc cctctctccg agcactgggc cctgcctggg
4381 ggctcccggg agccagggga gatgctacct cggaagctga agcggatcct ccggcaggag
4441 cactggccgt cttttgaaaa cttgctgaag tgcggcatgg aggtgtacaa aggctacatg
4501 gatgacccga ggaacacgga caatgcctgg atcgagacgg tggccgtcag cgtccacttc
4561 caggaccaga atgacgtgga gctgaacagg ctgaactcta acctgcacgc ctgcgactcg
4621 ggggcctcca tccgatggca ggtggtggac aggcgcatcc cactctatgc gaaccacaag
4681 accctcctcc agaaggcagc cgctgagttc ggggctcact actgactgtg ccctcaggct
4741 gggcggctcc agtccataga cgttcccccc agaaaccagg gcttctctct cctgagcctg
4801 gccaggactc aggctgttcc tgggccctgc acatgatggg gtttggtgga cccagtgccc
4861 ctcacggctg ccgcaagtct gctgcagatg acctcatgaa ctggaagggg tcaaggtgac
4921 ccgggaggag agctcaagac agggcacagg ctactcagag ctgaggggcc cctgggaccc
4981 ttggccatca ggcgaggggc tgggcctgtg cagctgggcc cttggccaga gtccactccc
5041 ttcctggctg tgtcaccccg agcagctcat ccaccatgga ggtcattggc ctgaggcaag
5101 ttccccggag agtcggggtc ccctgtggcc ccctcaggcc tatgtctgtg aggaaggggc
5161 cctgccactc tccccaagag ggcctccatg tttcgaggtg cctcaacatg gagccttgcc
5221 tggcctgggc taggggcact gtctgaactc ctgactgtca ggataaactc cgtgggggta
5281 caggagccca gacaaagccc aggcctgtca agagacgcag agggcccctg ccagggttgg
5341 ccccagggac cctgggacga ggctgcagaa gctctccctc cctactccct gggagccacg
5401 tgctggccat gtggccaggg acggcatgag caggaggcgg ggacgtgggg gccttctggt
5461 ttggtgtcaa cagctcacag gagcgtgaac catgagggcc ctcaggaggg gaacgtggta
5521 aaacccaaga cattaaatct gccatctcag gcctggctgg ctcttctgtg ctttccacaa
5581 ataaagttcc tgacacgtcc agggccaggg gctgtgtgac ggctgcctga agttctcctc
5641 gatcccccgg tgagcttcct gcagcctgtg gatgtcctgc agcccctcag ccctaccccc
5701 aagtttctcc tctgacccat cagctccctg tcttcatttt cctaaacctg ggctccagca
5761 tcgtccccaa gcccaccagg ccaggatgca ggcatccaca tgccctcctc cttggcttcc
5821 cctgcgtggt ggtgccaatg tgccctggca cccctgcaga ggctccggat ggagcctggg
5881 gctgcctggc cactgagcac tggccgaggt gatgcccacc cttccctgga caggcctctg
5941 tcttccacct gacccaaagc tctctagcca cccccttgtc cccagtat
//