LOCUS AB107015 4741 bp mRNA linear HUM 25-SEP-2004
DEFINITION Homo sapiens ALS2CL mRNA for ALS2 C-terminal like, complete cds.
ACCESSION AB107015
VERSION AB107015.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4741)
AUTHORS Hadano,S. and Ikeda,J.-E.
TITLE Direct Submission
JOURNAL Submitted (27-MAR-2003) to the DDBJ/EMBL/GenBank databases.
Contact:Shinji Hadano
Tokai University, The Institute of Medical Sciences; Bohseidai,
Isehara, Kanagawa 259-1103, Japan
REFERENCE 2
AUTHORS Hadano,S., Otomo,A., Suzuki-Utsunomiya,K., Kunita,R.,
Yanagisawa,Y., Showguchi-Miyata,J., Mizumura,H. and Ikeda,J.-E.
TITLE ALS2CL, the novel protein highly homologous to the
carboxy-terminal half of ALS2, binds to Rab5 and modulates
endosome dynamics.
JOURNAL FEBS Lett. 575, 64-70 (2004)
COMMENT
FEATURES Location/Qualifiers
source 1..4741
/chromosome="3"
/db_xref="H-InvDB:HIT000242301"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="liver"
CDS 85..2946
/codon_start=1
/gene="ALS2CL"
/product="ALS2 C-terminal like"
/protein_id="BAD51817.1"
/transl_table=1
/translation="MCNPEEAALLRLEEVFSATLAHVNSLVLQPLLPAAPDPSDPWGR
ECLRLLQQLHKSSQQLWEVTEESLHSLQERLRYPDSTGLESLLLLRGADRVLQAHIEY
IESYTSCMVVQAFQKAAKRRSEYWRGQRKALRQLLSGVSSEGSVGASLGQALHQPLAH
HVQQYVLLLLSLGDTIGEHHPTRELVVNAVTLFGNLQSFMKQELDQAVATQALWHTLR
GRLRDVLCTPAHRLLQDSQDVPVTVAPLRAERVLLFDDALVLLQGHNVHTFDLKLVWV
DPGQDGCTFHLLTPEEEFSFCAKDSQGQAVWQWKVTWAVHQALHGKKDFPVLGAGLEP
SQPPDCRCAEYTFQAEGRLCQATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHG
FGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESG
PQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQG
TFQADKTVGPGILLSEDDSLYEGTFTRDLTLMGKGKVTFPNGFTLEGSFGSGAGRGLH
TQGVLDTAALPPDPSSTCKRQLGVGAFPVESRWQGVYSPFRDFVCAGCPRDLQEALLG
FDVQSSRELRRSQDYLSCERTHPEDSVGSMEDILEELLQHREPKALQLYLRKALSNSL
HPLGKLLRTLMLTFQATYAGVGANKHLQELAQEEVKQHAQELWAAYRGLLRVALERKG
QALEEDEDTETRDLQVHGLVLPLMLPSFYSELFTLYLLLHEREDSFYSQGIANLSLFP
DTQLLEFLDVQKHLWPLKDLTLTSNQRYSLVRDKCFLSATECLQKIMTTVDPREKLEV
LERTYGEIEGTVSRVLGREYKLPMDDLLPLLIYVVSRARIQHLGAEIHLIRDMMDPNH
TGGLYDFLLTALESCYEHIQKEDMRLHRLPGHWHSRELW"
BASE COUNT 953 a 1373 c 1502 g 913 t
ORIGIN
1 gggggtgcga gcgaggagcc gcacaggcag tcccggcgcg gggcaaccac agcgctcagg
61 aggccctgag tccggcacct ggccatgtgc aaccctgagg aggcagctct gctgcggctg
121 gaggaggtct tctcagccac cctcgcccat gtcaacagcc ttgtcctcca gcccctgctc
181 ccagccgccc cagatccctc ggatccctgg ggcagagagt gcctgcggct cttgcaacag
241 ctgcacaaga gctcccagca actctgggag gtgacggagg aaagcctgca ctcactgcag
301 gagaggctgc gttacccgga ctccaccggt ctggagtccc tgctgctgct gcgaggtgct
361 gaccgtgtac tgcaggccca catagagtac attgagtcct acacaagctg catggtggtg
421 caggccttcc agaaggcagc aaagaggaga agcgagtact ggcggggcca gcggaaggcg
481 ctgcggcagc tgctttcagg tgtgagctca gagggctcgg tgggcgcatc gctgggccag
541 gccctccacc agccactcgc ccatcacgtg caacagtacg tgctcctcct gctgagcctc
601 ggggacacca ttggggagca tcacccaacc cgggagctgg tggtgaacgc agtcaccctc
661 tttgggaacc tgcagtcctt catgaagcag gagttggacc aggctgtggc cacacaggct
721 ctctggcaca ccctgagagg ccggctgagg gatgtgctct gcacccctgc tcacagactc
781 cttcaggaca gccaggacgt acccgtgacg gtcgcaccgt tgcgggctga gcgtgtgctg
841 ctctttgatg atgccctcgt cctgctgcag ggccacaatg tccacacctt tgatctgaag
901 ctggtgtggg tggatcctgg gcaggacggg tgcacgtttc acctcctcac gcccgaagaa
961 gagttctcct tttgtgccaa ggactcccag ggccaggcag tctggcagtg gaaggtgacc
1021 tgggctgttc accaggccct gcatgggaag aaggacttcc ccgtgctggg ggctggcctg
1081 gagccctccc agcctcccga ctgccgctgc gcagaatata ccttccaggc agagggccgg
1141 ctctgccagg ccacctacga gggcgagtgg tgcaggggcc ggccccacgg caagggaacc
1201 ctgaaatggc cggatgggcg gaatcatgtg gggaatttct gccagggcct ggagcatggc
1261 ttcggcatcc gcctgctgcc ccaggcctct gaggacaagt tcgactgtta caagtgtcac
1321 tggcgagaag gcagcatgtg tggctacggc atctgtgagt acagcaccga cgaggtgtac
1381 aagggctact tccaggaggg cctgcggcac ggatttgggg tccttgagag tggtccgcag
1441 gccccccagc ccttcaggta cacgggccac tgggagaggg gccagaggag cggctatggc
1501 attgaggagg atggtgacag aggtgagcgc tacattggca tgtggcaggc tggtcagcgc
1561 cacggcccag gggtcatggt cacccaggca ggtgtctgct accagggcac cttccaggcg
1621 gacaagacgg tgggcccggg catcctcctc tctgaagacg actccctgta tgagggcacc
1681 ttcaccaggg acctgaccct catggggaag ggcaaggtca ccttccccaa tggcttcacc
1741 ctggagggct cgttcggcag tggggcaggg agaggactgc acacacaggg tgtgctggac
1801 acggctgccc tcccaccaga cccgagcagt acctgcaaga ggcagctggg cgtgggtgcc
1861 ttccccgtgg aaagccgctg gcagggagtc tacagcccct tccgggactt tgtgtgtgct
1921 ggctgcccca gggacctgca ggaggccctg ctgggcttcg acgtgcagag ctccagggag
1981 ctgcgtaggt ctcaggatta cctgtcctgc gagaggaccc accctgagga cagtgtgggc
2041 agtatggaag acatcctgga ggagctgctg cagcaccggg agcccaaggc cctgcagctg
2101 tacctcagga aggctctgag caactcactg caccccctgg gaaagctgct ccggacactg
2161 atgctgacct tccaggctac ctacgcaggt gtcggggcca acaagcacct gcaggagctg
2221 gcccaggagg aggtgaagca gcatgcccag gaactctggg ctgcctacag gggtctgctg
2281 cgagttgcct tagagcgcaa gggccaggcc ctggaggagg atgaagacac agagacaagg
2341 gacctccagg tgcatggatt ggtgctgccc ctcatgctgc ccagcttcta ctcagagctc
2401 ttcacgctct acctgctgct tcatgagcgg gaggacagct tctacagcca gggcattgcc
2461 aacttgagcc tctttcctga tacccaactg ctcgagttcc tggatgtgca gaagcacttg
2521 tggcccctca aggacctcac gctgacgagc aatcagaggt actccctggt cagggacaag
2581 tgtttcctgt cagccaccga gtgcctgcag aagatcatga ccacggtgga cccacgggag
2641 aagctggagg tgctggagag gacatacggg gaaattgagg gcacggtgtc gagggtattg
2701 ggccgggagt acaagctgcc catggacgac ctgctgccac ttctcatcta cgtggtgtcg
2761 cgcgcccgaa ttcagcacct gggagccgag atccacctga tccgtgacat gatggacccc
2821 aaccacacag gaggcctgta tgacttcctg ctcacagccc tggagtcctg ttacgagcac
2881 atccagaaag aagacatgag gctgcaccgc ttacctggcc actggcactc cagggagctc
2941 tggtagcctg gcctttcctg gacagactga agagctgagc agggcactgc cagcctgtcc
3001 ctcattaccc aaggcaaggg gcaggacagg ccctcagaag cagctcttgg aggagatgag
3061 cattttgttt tgcacaggaa gatgctgctg ctgccctgac tgggatgagg gtgaggggtg
3121 acgggtgtgg ccctggatgt ggtggttttc ccttggccac tagcccatct tcaatgaccc
3181 cttaatctgc agcagctcac aggctggggg tgaggagtcc ctggcttctc ttagcctgag
3241 cctttctccc aagttccaga gcctctccgg gcctcagtgc tgccatctgt acaatggtgg
3301 agtgagtacg ctgtaaagga ccttccattc attttgctga attccagagt ccttttggaa
3361 aactgacttt agtctgctgg gctgtattga cctctggcag gctcgaagcc tcactgggta
3421 tgcagtcaac aggatgggcc tggagatccg tgaactgcag gccacgtacc catgacgtaa
3481 acggcggcac tggagcaagc tggggcgggg ggtgggtaaa ccctcactgc cagcaggccc
3541 caagtggctt gtaaatcatt ctcctgtgac gtctgtgggc ctgcgtgggg acaacagggg
3601 cacatgacat ctgcctgggc cctgaccaat aaaccctcag acccaggacc caggaccctg
3661 ctgtagttgg ggagcaggag tacctttggg aggggaggac tttatttaaa cagtggttct
3721 agtgtgggac caagagaggc aggagctggg tcttggggca gctttattcc tgttgggcct
3781 cagtttctct tccccacaca gtttatcttc cgtcacattg tgccgggtga cgtgcacggt
3841 ctccctctgc cctagcagga gatgcatgat gacaggcagt gtgatgtgtt ctgaaagtgt
3901 ccagggcaaa gcatagggag agggtggatt tgtgcagggt gcagctctgg agaagaagct
3961 ggatcactct tggtcccatt ccctaggccc tgagcaagtc aggctcctgg ctctgggtgt
4021 ggctccccca aacgaagtac tgacttcagc ctgtgagggg agggttgagg gaggctctgg
4081 aaagcccagc cacacctgag tccctggcag tagccttggg gcagagggca cccgcagagt
4141 cccagagatg atgtgggcag tgggcagaga gagccttggc gcctctgttt gccaccactt
4201 ccccaggaag gagggacagc atttctctgg ctggttccac taaatgtgcc agcccaaatg
4261 cagggcatgg gctctggttc tgccaggagc ctgtgacacc cccaggaagg gggtggaact
4321 gaggaagagc gaggatatgc aggcactcat gcttaccggg actggggcag ctcactagga
4381 ttctatcctt tccaatcggc atcagccagc tcttgtcccc tgataagtga ggacagcctg
4441 accctggcct caaatgcagc catccctgag ttcatgcgat gctgacggga ccccagcaca
4501 cttccctgcc tcctttgaga tctgcgagcc cttgctgcag ttcagattca acaaggccct
4561 ctgcccaccc tctcactagg cctcacccaa caccagtgga actggagcct ctggctgggc
4621 acagtggctc actttgggag gctgaggcag gaaggctgct ggaaactgag agttcaagac
4681 cagcctgggc aacatagtga gaccctgtct ctacaaatat aaaataaaat aattagctgg
4741 g
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