LOCUS AB083783 2580 bp mRNA linear HUM 23-DEC-2010
DEFINITION Homo sapiens slac2-c mRNA for Slp homologue lacking C2 domains-c,
complete cds.
ACCESSION AB083783
VERSION AB083783.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2580)
AUTHORS Fukuda,M.
TITLE Direct Submission
JOURNAL Submitted (15-APR-2002) to the DDBJ/EMBL/GenBank databases.
Contact:Mitsunori Fukuda
Tohoku University Graduate School of Life Sciences, Laboratory of
Membrane Trafficking Mechanisms, Department of Developmental
Biology and Neurosciences; Aobayama, Aoba-ku, Sendai, Miyagi
980-8578, Japan
REFERENCE 2
AUTHORS Fukuda,M. and Kuroda,T.S.
TITLE Slac2-c (Synaptotagmin-like Protein Homologue Lacking C2
Domains-c), a Novel Linker Protein that Interacts with Rab27,
Myosin Va/VIIa, and Actin
JOURNAL J. Biol. Chem. 277, 43096-43103 (2002)
COMMENT
FEATURES Location/Qualifiers
source 1..2580
/db_xref="H-InvDB:HIT000061411"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 1..2580
/codon_start=1
/gene="slac2-c"
/note="Slac2-c"
/product="Slp homologue lacking C2 domains-c"
/protein_id="BAC15555.1"
/transl_table=1
/translation="MGRKLDLSGLTDDETEHVLQVVQRDFNLRKKEEERLSELKQKLD
EEGSKCSILSKHQQFVEHCCMRCCSPFTFLVNTKRQCGDCKFNVCKSCCSYQKHEKAW
VCCVCQQARLLRAQSLEWFYNNVKSRFKRFGSAKVLKNLYRKHRLESGACFDILGGSL
FESNLENEGSISGSDSTFYRQSEGHSVMDTLAVALRVAEEAIEEAISKAEAYGDSLDK
QNEASYLRDHKEELTEELATTILQKIIRKQKSKSEQQVEEEPGWPHPQSCSTKVADEG
TSASPGGYRAPAALWRSQSAFSITGEEALKTPPVEAPSRQPRDQGQHPRAESALPSWK
SVDRLDETNLAPVLQSPDGNWVALKDGAPPPTRLLAKPKSGTFQALEVASSVASAYDE
MGSDSEEDFDWSEALSKLCPRSRALPRNPQPQPTQAQSSDQGPIAASPSSALSPNPEA
MCSDSETSSAGSSREVGHQARLSWLQRKAPRNPAAEKMRLHGELDVNFNPQLASRETS
DSSEPEEAPHTTDRRARRWRRARLGSEEPSKEPSSPSAQLRDLDTHQVSDDLSETDIS
NEARDPQTLTDTTEEKRRNRLYELAMKMSEKETSSGEDQESEPKTESENQKESLSSED
NSQSVQEELKKKFSAVSLCNISTEVLKVINATEELIAGSTGPWESPQVPPDRQKGMFP
RGTDQVRLDEQLTSLEENVYLAAGTVYGLETQLTELEDAARCIHSGTDETHLADLEDQ
VATAAAQVHHAELQISDIESRISALTIAGLNIAPCVRFTRRRDQKQRTQVQTIDTSRQ
QRRKLPAPPVKAEKIETSSVTTIKTFNHNFILQGSSTNRTKERKGTTKDLMEPALESA
VMY"
misc_feature 1..435
/function="Rab27A/B binding"
/note="SHD; Slp homology domain"
misc_feature 436..2577
/function="myosin Va binding"
/note="similar to the C terminus of Slac2-a/melanophilin"
BASE COUNT 709 a 689 c 730 g 452 t
ORIGIN
1 atggggagga agctggacct gtctggtttg actgatgatg aaacagagca tgttcttcag
61 gtggttcaaa gagacttcaa tcttcgcaaa aaagaagaag aacgactaag tgagctgaag
121 cagaagctgg atgaggaagg cagcaagtgc agcatcctct cgaagcacca gcagtttgtg
181 gagcactgct gcatgcgctg ctgctcgccc ttcaccttcc tcgtcaacac caagcgccag
241 tgtggagatt gcaaattcaa tgtctgcaag agctgctgct cctaccagaa gcacgaaaag
301 gcctgggtct gctgcgtctg ccagcaagcg aggcttctga gggcccaatc tctggaatgg
361 ttctacaata atgtgaagag ccgcttcaag cgctttggca gtgccaaggt tctgaagaac
421 ctgtacagga agcaccggct ggagagtggc gcgtgcttcg acattctagg aggaagcctt
481 tttgagtcaa acctggagaa tgaaggaagc atttctggca gtgattcaac attttatagg
541 cagtcagaag gacatagtgt gatggacacc ttggctgtgg ccctacgggt ggctgaagag
601 gccattgagg aagcaatttc caaagcagag gcatatgggg acagcctgga caagcaaaat
661 gaggccagtt acctgcggga ccacaaggag gagctaactg aggaactggc cacgacaatc
721 ctgcagaaga ttatacgaaa acagaagagc aaaagtgagc agcaagtgga agaagagcca
781 ggatggccac atccccagag ttgcagcaca aaggtggcag atgaggggac ctcagcatcc
841 cctggaggct accgtgctcc cgctgccctc tggaggtccc agtctgcctt ctcaatcact
901 ggagaagaag ccctgaagac ccctccagtg gaggctccat cgaggcagcc aagggaccaa
961 ggccaacacc cgagagcaga gtctgctctg cccagctgga agagtgtgga caggctggat
1021 gaaacaaacc tggccccagt tttgcagagc cccgacggga actgggtggc cctgaaggat
1081 ggcgctccac cccccacccg actactggcc aaacctaaga gcgggacgtt tcaggccctg
1141 gaggtggcct ccagtgtggc atctgcctac gatgagatgg gctccgatag cgaggaagac
1201 tttgactgga gtgaggcctt gagcaagctg tgtcccaggt cccgggccct gcccaggaac
1261 ccccagcctc agcccacaca ggcccagagc tctgaccaag gccccatagc tgcctcccca
1321 tcctctgcac tctcccccaa ccctgaggcc atgtgctctg actcggagac ctcctccgca
1381 ggctcttccc gagaagttgg gcaccaggcc agactgtcct ggttgcagag gaaggccccc
1441 aggaaccctg cagctgagaa gatgcgcttg catggagagc tggacgtgaa cttcaacccc
1501 cagttggcca gcagggagac ctcggacagc agcgagccgg aggaggcccc ccacaccaca
1561 gaccggcggg ccaggaggtg gagaagagcc cgactgggct cagaagagcc aagcaaagaa
1621 ccatcttccc ccagcgccca gctccgggat ctagacacac atcaggtgtc ggatgattta
1681 tcagagacag acatcagcaa tgaggctcgg gatccccaga ctctcacaga caccacagag
1741 gagaaacgga gaaacaggct gtacgagtta gcaatgaaaa tgagtgaaaa ggagacttct
1801 tcaggggagg atcaggagtc tgagcccaag acagaatctg agaaccagaa ggaaagtctg
1861 tcctctgaag acaacagcca gagtgtccag gaagagctga agaagaagtt ttctgctgtt
1921 tctctctgca acatctccac agaagtcctg aaagtcatca atgccacaga ggagttgata
1981 gcaggatcta cagggccctg ggagtcccca caagtccctc ctgacagaca gaaggggatg
2041 tttcctcgtg ggacagacca agtgagactg gatgagcagc tgacttccct ggaagaaaat
2101 gtatacctgg cagcaggcac tgtgtatgga ctggagaccc agctgactga gctagaagat
2161 gccgcccgct gcatccacag cggcactgat gagacccatc tggcggatct ggaggaccag
2221 gtggccacgg ctgcagccca agtccaccat gctgaactcc agatttcaga tattgagagc
2281 cggatttcag ccctgaccat tgcaggatta aacatagcac catgtgtgcg cttcacaaga
2341 agacgggatc agaagcaaag gacccaggta caaaccatag atacatcaag gcagcaaagg
2401 aggaaactgc ctgctccacc ggtgaaagct gaaaaaattg agacatcttc agtgactacc
2461 attaaaacat ttaaccacaa cttcattctc caaggctcct caacaaacag gactaaggaa
2521 aggaaaggca ccaccaagga tttgatggag cctgctctgg agtcagctgt gatgtactga
//