LOCUS AB074006 3836 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens OBPH1 mRNA for oxysterol binding protein homologue 1,
complete cds.
ACCESSION AB074006
VERSION AB074006.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3836)
AUTHORS Higashimoto,K., Soejima,H. and Mukai,T.
TITLE Direct Submission
JOURNAL Submitted (08-NOV-2001) to the DDBJ/EMBL/GenBank databases.
Contact:Ken Higashimoto
Saga Medical School, Department of Biochemistry; 5-1-1, Nabeshima,
Saga 849-8501, Japan
REFERENCE 2
AUTHORS Higashimoto,K., Soejima,H., Yatsuki,H., Joh,K., Uchiyama,M.,
Obata,Y., Ono,R., Wang,Y., Xin,Z., Zhu,X., Masuko,S., Ishino,F.,
Hatada,I., Jinno,Y., Iwasaka,T., Katsuki,T. and Mukai,T.
TITLE Characterization and Imprinting Status of OBPH1/Obph1 Gene:
Implications for an Extended Imprinting Domain in Human and Mouse
JOURNAL Genomics 80, 575-584 (2002)
REFERENCE 3
AUTHORS Nagase,T., Kikuno,R., Ishikawa,K., Hirosawa,M. and Ohara,O.
TITLE Prediction of the coding sequences of unidentified human genes.
XVII. The complete sequences of 100 new cDNA clones from brain
which code for large proteins in vitro
JOURNAL DNA Res. 7, 143-150 (2000)
REFERENCE 4
AUTHORS Engemann,S., Strodicke,M., Paulsen,M., Franck,O., Reinhardt,R.,
Lane,N., Reik,W. and Walter,J.
TITLE Sequence and functional comparison in the Beckwith-Wiedemann
region: implications for a novel imprinting centre and extended
imprinting
JOURNAL Unpublished (2000)
COMMENT
FEATURES Location/Qualifiers
source 1..3836
/chromosome="11"
/clone_lib="rapid-screen cDNA library panels in human
heart (OriGene)"
/db_xref="H-InvDB:HIT000061231"
/db_xref="taxon:9606"
/map="11p15.5"
/mol_type="mRNA"
/organism="Homo sapiens"
exon 1..78
/number=1
exon 79..235
/number=2
variation 87
/replace="a"
CDS 100..2739
/codon_start=1
/gene="OBPH1"
/gene_synonym="KIAA1534"
/inference="non-experimental evidence, no additional
details recorded"
/note="alternative splicing long form"
/product="oxysterol binding protein homologue 1"
/protein_id="BAB85686.1"
/transl_table=1
/translation="MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSGDNELYPLS
PGKDMEPNGPSLPRDEGPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKKETLKAQ
KENYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTP
KVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPS
SYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEPGTSPDASPSSLCGLP
ASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHSRKTESGSDQSETPG
APVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVLPTF
VLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYNP
ILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYG
NSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQA
QLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPS
GEVRRQRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRAR
ERQESLMPWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVAR
QTTFLGSPGPRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFV
PGGESPCPRCRKEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQ
SPRSWFLLCVFLACQLFINHILK"
exon 236..318
/number=3
exon 319..399
/number=4
exon 400..501
/number=5
exon 502..705
/number=6
exon 706..790
/number=7
exon 791..965
/number=8
exon 966..1158
/number=9
exon 1159..1343
/number=10
exon 1344..1425
/number=11
exon 1426..1524
/number=12
exon 1525..1621
/number=13
exon 1622..1720
/number=14
exon 1721..1818
/number=15
exon 1819..1908
/number=16
exon 1909..2045
/number=17
exon 2046..2231
/number=18
exon 2232..2358
/number=19
exon 2359..2497
/number=20
exon 2498..2600
/number=21
exon 2601..3836
/note="alternative splicing"
/number=22b
exon 2601..3567
/note="alternative splicing"
/number=22a
variation 2766
/replace="g"
regulatory 3550..3555
/regulatory_class="polyA_signal_sequence"
regulatory 3814..3819
/note="alternative"
/regulatory_class="polyA_signal_sequence"
polyA_site 3836
BASE COUNT 765 a 1231 c 1206 g 634 t
ORIGIN
1 gcagccaggc ccgcgccgcc agtggagccc ccgcgcgccc ggccggcccg gagcaccgag
61 ctcgcggcac ggtaggagaa gcccccgagc gcccacagca tgaaggagga ggccttcctc
121 cggcgccgct tctccctgtg tccaccttcc tccacccctc agaaagtcga cccccggaag
181 ctcacccgga acttgctcct cagcggagac aatgagctct acccactcag cccagggaag
241 gacatggagc ccaacggccc gtcgctgccc agggatgaag ggcccccgac cccaagctct
301 gccacgaagg tgccaccggc agagtacagg ctgtgcaacg ggtcagacaa ggaatgtgtg
361 tcccccaccg ccagggtcac caagaaggag actctcaagg cgcagaagga gaactaccgg
421 caggagaaga agcgcgccac acggcagctg ctcagcgctc tgacagaccc cagcgtggtc
481 atcatggctg acagcctgaa gatccgcggc accctgaaga gctggaccaa gctgtggtgc
541 gtgctgaagc cgggggtgct gctcatctac aagacgccca aggtgggcca gtgggtgggc
601 acggtgctgc tgcactgctg cgagctcatc gagcggccct ccaagaagga cggcttctgc
661 ttcaagctct tccacccgct ggatcagtcc gtctgggccg tgaagggccc caaaggtgag
721 agcgtgggct ccatcacaca gcccctgccc agcagctacc tgatcttcag ggccgcctcc
781 gagtcagatg gtcgctgctg gctggacgcc ctggagctgg ccctgcgctg ctctagccta
841 ctgagactgg gcacctgcaa gccgggccga gacggggagc cagggacctc gccagacgca
901 tcaccctcat cgctctgtgg gctgccagcc tcagccaccg tccacccaga ccaagacctg
961 ttcccactga acgggtcttc cctggagaac gatgcattct cagacaagtc ggagagagag
1021 aaccctgagg agtcagatac cgagacccag gaccatagcc ggaagacgga gagtggcagc
1081 gaccagtcag agacccctgg ggccccggtg cggagaggga ccacctatgt ggagcaggtc
1141 caggaggagc tgggggagct gggcgaggcg tcccaggtgg agacagtgtc agaggagaac
1201 aagagtctga tgtggaccct gctgaagcag ctacggccag gcatggacct gtcccgcgtg
1261 gtgctaccca cgttcgtact ggagccgcgc tccttcctga acaagctctc cgactactac
1321 taccacgcag acctgctctc cagggctgcg gtggaggagg atgcctacag ccgcatgaag
1381 ctggtgctgc ggtggtacct gtctggcttc tacaagaagc ccaagggaat caagaagccg
1441 tacaacccca tcctggggga gaccttccgc tgctgctggt tccacccgca gactgacagc
1501 cgcacattct acatagcaga gcaggtgtcc caccacccgc ccgtgtctgc cttccacgtc
1561 agcaaccgga aggacggctt ctgcatcagt ggcagcatca cagccaagtc caggttttat
1621 gggaactcgc tgtcggcgct gctggacggc aaagccacgc tcaccttcct gaaccgagcc
1681 gaggattaca cccttaccat gccctacgcc cactgcaaag gaatcctgta tggcacgatg
1741 accctggagc tgggtgggaa ggtcaccatc gagtgtgcga agaacaactt ccaggcccag
1801 ctggaattca aactcaagcc cttcttcggg ggtagcacca gcatcaacca gatctcggga
1861 aagatcacgt cgggagagga agtcctggcg agcctcagtg gccactggga cagggacgtg
1921 tttatcaagg aggaagggag cggaagcagt gcgcttttct ggaccccgag cggggaggtc
1981 cgcagacaga ggctgaggca gcacacggtg ccgctggagg agcagacgga gctggagtcc
2041 gagaggctct ggcagcacgt caccagggcc atcagcaagg gcgaccagca cagggccaca
2101 caggagaagt ttgcactgga ggaggcacag cggcagcggg cccgtgagcg gcaggagagc
2161 ctcatgccct ggaagccgca gctgttccac ctggacccca tcacccagga gtggcactac
2221 cgatacgagg accacagccc ctgggacccc ctgaaggaca tcgcccagtt tgagcaagac
2281 gggatcctgc ggaccttgca gcaggaggcc gtggcccgcc agaccacctt cctgggcagc
2341 ccagggccca ggcacgagag gtctggccca gaccagcggc ttcgcaaggc cagcgaccag
2401 ccttccggcc acagccaggc cacggagagc agcggatcca cgcctgagtc ctgcccagag
2461 ctctcagacg aggagcagga tggtgacttt gtccctggcg gtgagagccc atgccctcgg
2521 tgcaggaagg aggcgcggcg gctgcaggcc ctgcacgagg ccatcctctc catccgagag
2581 gcccagcagg agctgcacag gcacctctcg gccatgctga gctccacggc acgggcagca
2641 caggcaccga ccccaggcct cctgcagagc ccccgatcct ggttcctgct ctgcgtgttc
2701 ctggcgtgtc agctgttcat taaccacatc ctcaaatagg agccctgggg gcagagctcc
2761 tggccagtcc cgagccctcc ctcccaggca cccagcactt taagcctgct ccatggaggc
2821 agagaggccc ggcaagcaca gccactgtga cggggagtcc aggcgcagga gggacccggg
2881 gccacaaggg cgctgcgggc ccaggtgtgc tgggcccctc tcaggggcac tggcctctct
2941 gcagggcctt ccgcccagcg ctggccttaa tgctaaagcc aaatgcagct tctgctgtgc
3001 gacgcactcc tggccatctt gccgtgtcac cccctgtccg gcctccactt gccatggggg
3061 atggatggat ttagggtggg agggcctgtg ggggccctgg acagtcacac cccagcagca
3121 gtgagtgggc aggtttggag gagcagccag ggagccccga gtggcccagg agtcccccca
3181 cacacagatg cataggcctg ccttccggag accctgtcca cattgccggg accaccctgg
3241 tggggccact ggtgggtgcc agggacaggt tagggccact ctggggaagg cattttggtt
3301 ttttattcca cgctgtgctg tttggatggg agccccacag aggcaggtcc tggaaccacc
3361 ccacccccac acctggacgc tcgctctggt gggggcacac gcaggtggag gtggttgtgg
3421 gtgcaggtgt gtgcaggggt gtggggggcg caggggtgtg gcttagctgg ccccgcaccc
3481 aggccgggga ggctcaagtt cgccacttta ctcagaccga tgcacagtct tcccatttta
3541 cactttttta ataaacataa ttgcaatatt ttaggtgggc tgcgagctgc agtcagcctt
3601 cacgtctggc ctcagtcccc gtgtcagtgc cgctctgcgt gtgcgtgtgc gcgtgtgtga
3661 gcctctacac atatatatac gtacagagcc ttaaaccaca tcgtggcggt gccgtctgag
3721 ctgtagcggg tggctttgtt tccagttttt gtacccgtgt ccttgtctcc cctcctcccc
3781 catctgggga tgtgtctgtg ttccacacct tgaaataaac agacacatac gtgttc
//