LOCUS AB073146 6093 bp mRNA linear HUM 04-OCT-2008
DEFINITION Homo sapiens CLCP1 mRNA for CLCP1, complete cds.
ACCESSION AB073146
VERSION AB073146.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6093)
AUTHORS Koshikawa,K., Konishi,H., Osada,H. and Takahashi,T.
TITLE Direct Submission
JOURNAL Submitted (16-OCT-2001) to the DDBJ/EMBL/GenBank databases.
Contact:Takashi Takahashi
Aichi Cancer Center Research Institute, Division of Molecular
Oncology; Chikusa-ku, Kanokoden 1-1, Nagoya, Aichi 464-8681, Japan
REFERENCE 2
AUTHORS Koshikawa,K., Osada,H., Kozaki,K., Konishi,H., Masuda,A.,
Tatematsu,Y., Mitsudomi,T., Nakao,A. and Takahashi,T.
TITLE Significant up-regulation of a novel gene, CLCP1, in a highly
metastatic lung cancer subline as well as in lung cancers in vivo
JOURNAL Oncogene 21, 2822-2828 (2002)
COMMENT
FEATURES Location/Qualifiers
source 1..6093
/cell_line="normal lung tissue"
/chromosome="3"
/db_xref="H-InvDB:HIT000061214"
/db_xref="taxon:9606"
/map="3q12.1-q12.2"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="lung"
CDS 364..2691
/codon_start=1
/experiment="experimental evidence, no additional details
recorded"
/function="associated with metastatic phenotype"
/gene="CLCP1"
/note="CUB, LCCL, coagulation factor V/VIII-homology
domains protein 1"
/product="CLCP1"
/protein_id="BAB91138.1"
/transl_table=1
/translation="MASRAVVRARRCPQCPQVRAAXAAPAWAALPLSRSLPPCSNSSS
FSMPLFLLLLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWE
IRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIES
KGNEITLLFMSGIHVSGRGFLASYSVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLP
FAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSV
VGHLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLK
KPGPPWAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKW
TVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQKIAMKMELLGCQ
FIPKGRPPKLTQPPPPRNSNDLKNTTAPPKIAKGRAPKFTQPLQPRSSNEFPAQTEQT
TASPDIRNTTVTPNVTKDVALAAVLVPVLVMVLTTLILILVCAWHWRNRKKKTEGTYD
LPYWDRAGWWKGMKQFLPAKAVDHEETPVRYSSSEVNHLSPREVTTVLQADSAEYAQP
LVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPGQEVYHAYAEPLPITGPEYATPII
MDMSGHPTTSVGQPSTSTFKATGNQPPPLVGTYNTLLSRTDSCSSAQAQYDTPKAGKP
GLPAPDELVYQVPQSTQEVSGAGRDGECDVFKEIL"
misc_feature 577..924
/note="CUB domain"
misc_feature 934..1191
/note="LCCL domain"
misc_feature 1234..1710
/note="F5/8 type C domain"
misc_feature 1942..2010
/note="transmembrane domain"
regulatory 4264..4269
/regulatory_class="polyA_signal_sequence"
regulatory 5873..5878
/regulatory_class="polyA_signal_sequence"
regulatory 6052..6057
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1671 a 1258 c 1289 g 1874 t
ORIGIN
1 gcctgccagc tagccggagc cgcgggtgag cgcggcgagc ggcgaccctg gtgaggagcg
61 cggcgcggga ggcacgttcc ttagctccgc cgcggccgtc ctccgcggct cgaggactcc
121 gcttccttcc ctcccctccc ctgcgctccg gcctggggtc tcggcgcggg gagcggaggg
181 aagggacgaa ggaggagtag gtgaaagcgg ggtgaggggc ggaagggtcc cggcgcgggg
241 tgaggcgagg gctgcctctt gttctcccgc cgctgccgcc gtctcctggt cgggtgccgc
301 ggccagaggc gcgcggggct gccgaggcac ccgcactatg caggcagact gccggccgcc
361 gcgatggcga gccgggcggt ggtgagagcc aggcgctgcc cgcagtgtcc ccaagtccgg
421 gccgcgnccg ccgcccccgc ctgggccgcg ctccccctct cccgctccct ccctccctgc
481 tccaactcct cctccttctc catgcctctg ttcctcctgc tcttacttgt cctgctcctg
541 ctgctcgagg acgctggagc ccagcaaggt gatggatgtg gacacactgt actaggccct
601 gagagtggaa cccttacatc cataaactac ccacagacct atcccaacag cactgtttgt
661 gaatgggaga tccgtgtaaa gatgggagag agagttcgca tcaaatttgg tgactttgac
721 attgaagatt ctgattcttg tcactttaat tacttgagaa tttataatgg aattggagtc
781 agcagaactg aaataggcaa atactgtggt ctggggttgc aaatgaacca ttcaattgaa
841 tcaaaaggca atgaaatcac attgctgttc atgagtggaa tccatgtttc tggacgcgga
901 tttttggcct catactctgt tatagataaa caagatctaa ttacttgttt ggacactgca
961 tccaattttt tggaacctga gttcagtaag tactgcccag ctggttgtct gcttcctttt
1021 gctgagatat ctggaacaat tcctcatgga tatagagatt cctcgccatt gtgcatggct
1081 ggtgtgcatg caggagtagt gtcaaacacg ttgggcggcc aaatcagtgt tgtaattagt
1141 aaaggtatcc cctattatga aagttctttg gctaacaacg tcacatctgt ggtgggacac
1201 ttatctacaa gtctttttac atttaagaca agtggatgtt atggaacact ggggatggag
1261 tctggtgtga tcgcggatcc tcaaataaca gcatcatctg tgctggagtg gactgaccac
1321 acagggcaag agaacagttg gaaacccaaa aaagccaggc tgaaaaaacc tggaccgcct
1381 tgggctgctt ttgccactga tgaataccag tggttacaaa tagatttgaa taaggaaaag
1441 aaaataacag gcattataac cactggatcc accatggtgg agcacaatta ctatgtgtct
1501 gcctacagaa tcctgtacag tgatgatggg cagaaatgga ctgtgtacag agagcctggt
1561 gtggagcaag ataagatatt tcaaggaaac aaagattatc accaggatgt gcgtaataac
1621 tttttgccac caattattgc acgttttatt agagtgaatc ctacccaatg gcagcagaaa
1681 attgccatga aaatggagct gctcggatgt cagtttattc ctaaaggtcg tcctccaaaa
1741 cttactcaac ctccacctcc tcggaacagc aatgacctca aaaacactac agcccctcca
1801 aaaatagcca aaggtcgtgc cccaaaattt acgcaaccac tacaacctcg cagtagcaat
1861 gaatttcctg cacagacaga acaaacaact gccagtcctg atatcagaaa tactaccgta
1921 actccaaatg taaccaaaga tgtagcgctg gctgcagttc ttgtccctgt gctggtcatg
1981 gtcctcacta ctctcattct catattagtg tgtgcttggc actggagaaa cagaaagaaa
2041 aaaactgaag gcacctatga cttaccttac tgggaccggg caggttggtg gaaaggaatg
2101 aagcagtttc ttcctgcaaa agcagtggac catgaggaaa ccccagttcg ctatagcagc
2161 agcgaagtta atcacctgag tccaagagaa gtcaccacag tgctgcaggc tgactctgca
2221 gagtatgctc agccactggt aggaggaatt gttggtacac ttcatcaaag atctaccttt
2281 aaaccagaag aaggaaaaga agcaggctat gcagacctag atccttacaa ctcaccaggg
2341 caggaagttt atcatgccta tgctgaacca ctcccaatta cggggcctga gtatgcaacc
2401 ccaatcatca tggacatgtc agggcacccc acaacttcag ttggtcagcc ctccacatcc
2461 actttcaagg ctacggggaa ccaacctccc ccactagtgg gaacttacaa tacacttctc
2521 tccaggactg acagctgctc ctcagcccag gcccagtatg ataccccgaa agctgggaag
2581 ccaggtctac ctgccccaga cgaattggtg taccaggtgc cacagagcac acaagaagta
2641 tcaggagcag gaagggatgg ggaatgtgat gtttttaaag aaatcctttg aagatgatgc
2701 tgctttttac aaagcatcgt tttaaagcac atggcctttt ttttttaatt attagtggta
2761 gtaatatata gaatgtatta cataactgtc actgaagtgg ttggggaaaa tgtggtgact
2821 gaggtacagg aaactactaa tcttgccatc ttgctttaag gtgttatggt ggcacagtta
2881 ctgctcgcct gttaaatttc aaatgtcctg tttgatacta ctgtagaaca ctatttttaa
2941 tacagaaaaa gctccctata atgcacttca gagaaattaa aaatcacaga gtatttatta
3001 ccaatgctgc aggtacatta atgaactcga gatggctctg taagcctgac tggcaataac
3061 gcacggtact gttcttgaaa tacctaatgg cttgaaattc tagtctgttt gtgaaagatg
3121 ggtactatca tgatttcctc ttctattcct atattctttt ctggattttt tttaataatt
3181 agtgatataa gcattgtttt tattgcagcc atatccactt atccatctta agatctgtag
3241 ctgggatttt ctgacttgta atgagcaggg ggattgcttt ttcactttgt gacactcttt
3301 agagctttaa tgcttcacag tatatggcct ggtctcatcc ttgcgtgttc cacttgaggc
3361 cctttggtgt cttgccccat tcttgtgttt ataaaatgtt tgagtatttc tgatgagtga
3421 tgcttgcctt agtctcatga attcagatcc cttcatgtcc tttaagtatg ctcctcaatg
3481 tgtaaacagg aacaacttta tgatttgaaa gctttaaagg agattcttct cccaccccca
3541 actttatttg caatgggatt tttcctagga gagttatgaa aagttgaagg cttctaaggg
3601 aatactgtaa acatgaccca cttatattta tcacagtgaa aggcaaaatt attcactcag
3661 aagtaatata aattacctct ttaaaaagta accagaattt gtcctttttg gttttataca
3721 ttcacaaaca tatacatttt tcttgagtct caaggtattt tatattttta gtcagaaaaa
3781 ataatttttc atttcagttt tccataaact gttacacaaa atataaacct aacgtgtatt
3841 tttcaggact gcgtgatcgt gcactttgtg tggtaagagg tttgagtagt cctatatgtc
3901 acctagggaa cagacattat agcttactag caaatgaata ttcatgcctt gtttttgata
3961 cctcctggca gcttccatgt caccacttgt tcatacctgc ccagagctag ttttagacat
4021 ggcaaaatag aaatcatctg taatttatta gctaacaatg taaaaccatc ttttaaagcc
4081 ttcagactgt caagacgaca tgagcagctc accatatgat aaaaatacat aaatttgaca
4141 ttccctcttc cataaacctt tgtttgtaga tttaatgttg aacagtactt ttccataaag
4201 ttctagtcac ttctgttggc ctgagccacc agattatgat gttgccagaa ttcactcaat
4261 ttgaataaag atgaacagta tttgttttct tgtttccatg aattatatca gtattctaaa
4321 acatcgcttc agaaagagaa ctgtttattt ctgcaggctt cctgtccttt tgtggtatgg
4381 ttttttggcc ttattttcac tggcttttcc ttctccaaac tttgaggcgt gatttcattc
4441 attgaagaat caatacatat tttgtttcaa aatgtttgaa acaaaagaca tagatggtag
4501 acttttatta aaacatatat ggatgtggaa agcacatata ttaatgcagt catccctttt
4561 caggtgggaa gagagcaaac cagttgattt tttaattcat ccttagtaca cagagaatat
4621 acttttcctc aagtaatata cctgtttgaa gctttaagag agatgttttt ggtaactatt
4681 tcattttccc aaagaagttt gctattcttg tgttaattgt gtatacctga ttgttttttc
4741 ctggaggttt ttgttgttgt tgtttagttt tgggtttttt tttttttaag aggggcaagt
4801 gttttctgaa atgatgcata ttttaagact cgattcatat tgccactgtg ctatccttga
4861 actaccaata atttttataa aatatctagt ttttactact tttatataaa ctttactttc
4921 cagatgaaga gctgagcctg attcaaatgg tttttctgct ttatacttct ttttagttca
4981 ttggttttta tagtagaggt tttctatttt tttttttttt ttttttacta catttatatg
5041 tctgatacat atacggcttt ggagacaatc aagtaacaac tgaaaatgtg aaagtaacca
5101 tatctgacaa aattcccttg aatttttatc ctttgcttgc aacatttaag actcaaagtc
5161 actggtatat tggattaagt tttttcctgt taatgcaatt atagaaatac atcggagaca
5221 caacaaatgt ggccattaca ggtttcataa aattacactg acttggctgt tacttgatct
5281 taggaaacag cacagtttaa gatattgtga attctgactt atactttatt aaatgctgta
5341 aatctaaata gatcctgttg gatgtgatgg gtctagtcca gtttatttaa gttcatgttt
5401 cactgtttgc actttgcatt gaacaatggg tttattcgct gatgtaaacg gttcgagtga
5461 agaattaatg cagtaagtat gacaacacat acacacttgc ctctccccat ctccagaaga
5521 ggggagcaga gtccgagctt atctaaatat gaatgtggcc acaaagctgt ggaaggtgac
5581 aaagcttaaa cacctttgcc ctggctctgc attgtcacct agagagcaag aggtctatag
5641 aaacatcatg tcacatgaaa cgattctctg ctttttggtt ctgaacttga agtccctaaa
5701 ctgcaaaatc taagagttgg gtggttatta aaatgctttt aaagtcaact gtggcaccaa
5761 ttctaatgta atccaacttg tgactgtttt tttttgtttt gttttgtttt tgtgtgtgtg
5821 tgtgtggcac tgggaaaagt ggaaacaaac atgtattgaa atacatattg gaaataaaaa
5881 tggtttgagc gtcagtgata ttctcccaga atgtacttat cttacctcgg catgtactgt
5941 agtcactcag tatttgtata tgttgctaga atttagattg taaaatagtg aaattttaat
6001 gtgttcattt gtttttaatg tatatatgtc ttgctcagat tatttggttt aaataaaaca
6061 accttgaggt ttgtagcttt tccttatact ata
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