LOCUS AB061683 8618 bp mRNA linear HUM 05-MAR-2002
DEFINITION Homo sapiens PKD1L1 mRNA for polycystin-1L1, complete cds.
ACCESSION AB061683
VERSION AB061683.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8618)
AUTHORS Yuasa,T., Venugopal,B., Weremowicz,S., Guo,L. and Zhou,J.
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) to the DDBJ/EMBL/GenBank databases.
Contact:Takeshi Yuasa
Brigham and Women's Hospital, Department of Medicine, Renal
Division; Harvard Institute of Medicine #520, 77 Avenue Louis
Pasteur, Boston, MA 20115, USA
REFERENCE 2
AUTHORS Yuasa,T., Venugopal,B., Weremowicz,S., Morton,C.C., Guo,L. and
Zhou,J.
TITLE The Sequence, Expression, and Chromosomal Localization of a Novel
Polycystic Kidney Disease 1-Like Gene, PKD1L1, in Human
JOURNAL Genomics 79, 376-386 (2002)
COMMENT
FEATURES Location/Qualifiers
source 1..8618
/db_xref="H-InvDB:HIT000059843"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="testis"
CDS 1..8550
/codon_start=1
/gene="PKD1L1"
/product="polycystin-1L1"
/protein_id="BAB85807.1"
/transl_table=1
/translation="MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSC
SPPGGGLWVEVYANHVLLMSDGKCGCPWCALNGKAEDRESQSPSSSASRQKNIWKTTS
EAALSVVNEKTQAVVNEKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCA
TGTADSTFSALLQLQGTTSAAAPCSLKMEASCCVLRLLCCAEDVATGLLPGTVTMETP
TKVARPTQTSSQRVPLWPISHFPTSPRSSHGLPPGIPRTPSFTASQSGSEILYPPTQH
PPVAILARNSDNFMNPVLNCSLEVEARAPPNLGFRVHMASGEALCLMMDFGDSSGVEM
RLHNMSEAMAVTAYHQYSKGIFFHLLHFQLDMSTYKEAETQNTTLNVYLCQSENSCLE
DSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTEVELGPYYVEIGHEAVSAFMNSSS
VHEDEVLVFADSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMTVWYKMQS
VSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFGEDPPVRTTSRSIKKRLSIPQWYR
VMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPSSALVNASVAFECWINFGTDVAYLW
DFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKNM
GPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLMDSEGLPVSLPAAVDTHRQTL
ILPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRTTSS
PIVLRGTQSFDPDDPGATLRYHWECATAGSPAHPCFDSSTAHQLDAAAPTVSFEAQWL
SDSYDQFLVMLRVSSGGRNSSETRVFLSPYPDSAFRFVHISWVSFKDTFVNWNDELSL
QAMCEDCSEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGLGAISESSQLNLL
PTEPGTADPDATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVYWIPPAGDSAVLGE
APEEGSLDLEPGPQSKGSLMTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGGRQP
AKDTSFPGSGPSLSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSS
SGITEQTVTIKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQVQPHH
GLEAHTVFSVFCMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNYKV
MVSTEITDGKGSKVQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIR
NYITVITRILSRLSKEDKTASCNQWSRIQDALISSVCRLAFVDQEEMIGSVLMLRDLV
SFSNKLGFMSAVLILKYTRALLAQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSK
EEVYRHEEGITVISDLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGD
LAGHSPAGAETQSPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQW
LRKPVMVEFGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIEFSKPVT
RAFPVMLLVRFSEKPTPSDFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYD
RKPPNRYLAKAVNYTVHFQWIRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFA
LLRRKLKASFEVSDISKLQSHPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGY
IFLQEASLPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFER
NSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLS
AGRHDGRVERELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLT
VSFSLLCVYACLTALVAAGGQEQPHLDVSPTLGSFRVGLLCTLLASPGAQLLSLLFRL
SKEAPGSARVEPHSPLRGGAQTEAPHGPNSWGRIPDAQEPRKQPASAILSGSGRAQRK
AASDNGTACPAPKLQVHGADHSRTSLMGKSHCCPPHTQAPSSGLEGLMPQWSRALQPW
WSSAVWAICGTASLACSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCLM
ALGFAWKRRADNHFFTESLCEATRDLDSELAERSWTRLPFSSSCSIPDCAGEVEKVLA
ARQQARHLRWAHPPSKAQLRGTRQRMRRESRTRAALRDISMDILMLLLLLCVIYGRFS
QDEYSLNQAIRKEFTRNARNCLGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQP
GALGGKCYLIGSSVIRQLKVFPRHLCKPPRPFSALIEDSIPTCSPEVGGPENPYLIDP
ENQNVTLNGPGGCGTREDCVLSLGRTRTEAHTALSRLRASMWIDRSTRAVSVHFTLYN
PPTQLFTSVSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHLMLPQLVFLALSLIHL
CVQLYRMMDKGVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGDVTNQFHRGLCR
AFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSSMMRHSLPSIFVAG
LVGALMLAALSHLHRFLLSMWVLPPGTFTDAFPGLLFHFPRRSQKDCLLGLSKSDQRA
MACYFGILLIVSATLCFGMLRGFLMTLPQKRKSFQSKSFVRLKDVTAYMWEKVLTFLR
LETPKLEEAEMVENHNYYLDEFANLLDELLMKINGLSDSLQLPLLEKTSNNTGEARTE
ESPLVDISSYQAAEPADIKDF"
BASE COUNT 2008 a 2319 c 2174 g 2117 t
ORIGIN
1 atggccgagg aggcagccca gaacatttct gatgaccagg aaaggtgtct ccaggctgcc
61 tgctgccttt cctttggtgg tgagctgtct gtgagcactg acaagagctg gggtcttcat
121 ctgtgcagct gtagccctcc tggaggtgga ttgtgggtcg aggtctatgc taatcatgtg
181 cttcttatga gtgatgggaa gtgtggctgt ccttggtgtg ctctgaatgg aaaggcagaa
241 gaccgggaat cacagagccc atcctcatca gcttccaggc agaagaacat ttggaaaaca
301 actagtgaag cagcgttaag tgttgttaat gaaaaaacac aggctgttgt taatgaaaaa
361 acacaggcgc ctctggattg tgataacagt gctgatagaa ttccccacaa acctttcatt
421 ataatcgcaa gggcctggag cagtggtggc cccaggttcc atcacaggcg gctgtgtgct
481 actgggaccg cagacagcac attctctgct cttctccagc tccagggcac cacttctgca
541 gcagctccct gcagcctgaa gatggaggct tcctgctgtg tcctgagact gctgtgctgt
601 gcggaggatg tggccacggg gctgcttcct gggactgtca cgatggagac ccccaccaag
661 gtggccagac ccactcagac cagctcccag cgagtgcccc tgtggccgat ttcacatttt
721 cccacttctc ccagaagctc ccacggcctt ccgcctggca ttcctcgcac ccccagcttc
781 acggcatcgc agtctggttc tgagatcctc tatcccccta ctcagcatcc tcctgtggcc
841 atcctagctc gaaattctga taacttcatg aaccctgttc ttaattgctc cctggaagtg
901 gaagctcggg cacctccaaa tctgggattc cgtgttcata tggcttctgg agaggctctc
961 tgtctgatga tggatttcgg ggacagttct ggggttgaaa tgaggctaca caacatgtct
1021 gaggcaatgg cggtgactgc ctaccaccag tactcaaaag gtattttttt tcatctttta
1081 cattttcagt tggatatgtc cacctacaaa gaagcagaga cacaaaatac aactttaaat
1141 gtttacttgt gccaaagtga aaacagctgc ctggaagact cagaccccag taaccttgga
1201 tatgagctta tttctgcctt tgtcaccaaa ggagtctata tgctcaaggc tgttatttat
1261 aacgagtttc atggaaccga agtggagctt gggccttatt atgtggagat tggccatgag
1321 gccgtgtctg cgttcatgaa ctccagcagt gtccatgaag atgaagtgct tgtctttgct
1381 gactcccaag tgaatcagaa aagcactgtg gttatacatc actttccatc tattccttca
1441 tataacgtgt cctttatttc tcagactcaa gtgggtgaca gccaggcttg gcacagcatg
1501 actgtctggt ataagatgca atccgtctct gtctacacaa atggaactgt gtttgccaca
1561 gacacagaca ttacatttac agctgttacc aaggaaacaa tacccctgga atttgagtgg
1621 tattttggag aggatccacc agtgaggaca acttcaagaa gcattaaaaa aagactcagc
1681 atcccccaat ggtatcgtgt gatggttaag gcttccaaca ggatgagcag tgtggtctct
1741 gagccccatg tcatcagggt gcagaagaaa attgtggcca atcggctcac gtccccctcc
1801 tcagctctgg taaatgccag tgtggccttt gagtgctgga tcaacttcgg cacagatgtt
1861 gcctacctgt gggactttgg ggatggcacc gtcagcctgg ggagcagctc cagcagccat
1921 gtctacagta gggaaggaga atttacagtg gaggtccttg ccttcaataa tgtcagtgcc
1981 tccactctaa gacagcaact tttcatcgtg tgcgagccct gccagccacc cctggtgaag
2041 aacatggggc ctgggaaagt ccagatatgg aggtctcagc ctgtgaggct gggagtgacg
2101 tttgaagctg cagtcttctg tgatatttcc caaggtcttt cttacacctg gaacttgatg
2161 gactctgaag ggctccctgt ctccctccct gctgctgtgg acactcacag acagaccctc
2221 atcctcccga gccacacctt ggagtatggg aactacactg cccttgccaa ggttcagatt
2281 gaaggcagtg tggtgtacag caactactgt gtgggcctgg aggtgcgagc ccaggcccct
2341 gtcagtgtga tctccgaggg cacacaccta ttcttctcca ggaccacctc atcccccatt
2401 gtcctcagag ggacccagtc cttcgaccct gacgaccctg gggcgactct caggtatcac
2461 tgggaatgcg ccaccgctgg ctccccagca catccctgct tcgactcctc cactgcacac
2521 caactggatg ccgcggctcc cactgtttcc tttgaggcac aatggctcag tgacagctat
2581 gatcagttcc ttgtgatgct gagggtctcc agtggtggcc ggaactcttc tgagacccgg
2641 gtgttcctgt ccccctaccc tgactcggcg ttcagattcg tccacatctc ctgggtcagc
2701 tttaaagaca ccttcgtcaa ctggaatgac gaactctctc ttcaagctat gtgtgaggac
2761 tgcagtgaaa taccgaatct gtcttattcc tgggatctct ttttagtcaa tgcaacagaa
2821 aagaatagga tagaagttcc cttctgcaga gtagtggggc tgcttggctc gctgggactc
2881 ggtgccattt cagagtcatc acagttaaac ctgctgccca ctgagcctgg cactgcagat
2941 cctgatgcaa cgaccacacc attctcacgg gaaccttcac ccgtgaccct tggccaacct
3001 gccacttcag ctccaagggg aacccccaca gagcccatga ctggagtcta ctggattcct
3061 cctgcggggg actctgcagt cctgggggag gctccagagg aaggttcact agacctagag
3121 ccagggccac agagcaaggg atccctgatg actggccgct ctgagagaag tcagcccacc
3181 cacagccctg accctcacct ctctgatttt gaagcctatt acagtgacat tcaagaagca
3241 ataccatcgg gaggaagaca gccagctaag gacaccagct ttccaggatc aggacctagc
3301 ttgagtgccg aggagagccc tggagatggg gataacctgg tggacccctc cctgtctgca
3361 ggcagagccg agcctgtcct catgattgac tggcccaagg ccctgctggg tcgagcagtt
3421 ttccaaggct attcatcctc aggtattaca gaacagacag tgacaatcaa gccatactct
3481 ctgagcagtg gagagacgta cgtcctgcaa gtgtctgtgg cttcgaagca tggcttactg
3541 ggtaaagctc agctgtactt gacagtcaac ccggctcctc gggacatggc ctgtcaggtg
3601 cagccccacc atggtctgga agcacacacc gtcttcagtg tcttctgcat gtctggaaaa
3661 ccggacttcc attatgaatt tagttaccag ataggaaaca cctccaaaca cactttgtac
3721 catgggagag acacccagta ttattttgtg ttgccagctg gtgagcactt ggacaattac
3781 aaagtcatgg tttccactga aatcacagat ggcaaaggct ccaaggtcca gccgtgcact
3841 gtggtggtga ctgtgctgcc ccgctaccat ggaaatgact gtctgggcga ggacctgtat
3901 aattccagcc tgaaaaacct ttctaccctc cagctgatgg ggagttacac agaaatcagg
3961 aactacatca ctgtgatcac cagaatcctg agtcgtttgt ctaaggagga caaaactgcc
4021 tcctgcaacc aatggtcacg aatacaggat gcattaattt cttcagtatg cagattggct
4081 tttgtagatc aggaagaaat gattggttct gttcttatgt tgagggacct cgtgagcttc
4141 tctaataagc taggctttat gagtgcggtt ctcatcctca agtacacccg ggcactcctt
4201 gctcaaggcc agttctcggg gccatttgtg attgacaaag gagtgaggct tgagctcatc
4261 ggtctcatat ccagagtctg ggaagtctct gagcaagaaa actcgaagga ggaagtctat
4321 cgacatgaag aaggaattac agtcatctca gatttattgt tgggttgtct ctctttgaac
4381 catgttagca ctgggcagat ggagttccgg acccttcttc attacaacct tcagagctct
4441 gtccagagcc tgggatctgt ccaggtgcat ttacctggtg accttgctgg gcacagtcct
4501 gctggggcgg agacacagag cccatgctac attagccagc tcatactctt caagaagaac
4561 ccatatccag ggagccaagc tcctgggcag attggtggag ttgtgggcct caacctctat
4621 acctgctcca gcagaagacc catcaacagg caatggctaa ggaaacccgt gatggtcgag
4681 tttggggagg aggatggcct ggataatagg agaaataaaa cgacatttgt attacttcgg
4741 gataaagtga atctccatca gttcactgag ctttccgaaa acccccagga atctctacag
4801 atagaaattg aattttccaa acctgttaca agggcatttc ccgtcatgtt gctagtaaga
4861 ttctctgaga aacctactcc ctctgatttt cttgtgaagc agatctactt ctgggatgag
4921 tcaattgtgc agatttatat acctgctgct tctcagaaag atgccagtgt aggctattta
4981 tccttattgg atgctgacta tgacagaaaa cctccaaaca gatatttagc taaggcagtg
5041 aactatacag tacatttcca gtggatccga tgcctgtttt gggacaagag agagtggaaa
5101 tctgaacgtt tctctccaca accagggact tctcctgaaa aagtgaactg cagctaccat
5161 cgcctcgcgg cattcgctct cctaaggaga aagctgaagg ccagttttga agtgagtgac
5221 atttccaagc tacagagcca cccagaaaac ttgcttccca gtatttttat tatgggttct
5281 gtgattcttt atggattttt ggtcgctaaa agtagacaag tagatcatca tgaaaaaaag
5341 aaagctggtt acatctttct gcaagaagct tccctgccgg gccatcagct atatgcggtc
5401 gtcattgaca ctggcttccg agctccggcc aggttgacct caaaggtgta cattgtttta
5461 tgtggcgaca atggactgtc agaaaccaag gagctctcct gtccagagaa gcccctgttt
5521 gaaaggaatt ccagacacac ctttatcctg agcgctcctg cccaactggg cctgctgagg
5581 aagatccgcc tctggcacga cagccgtggg ccttccccag gctggttcat cagccacgtg
5641 atggtgaagg agctgcacac gggacagggc tggttcttcc ctgcccagtg ctggctgtct
5701 gccggcaggc atgatggtcg cgtggagcgg gagctcacct gtctgcaagg gggactcggc
5761 ttccggaagc ttttctattg caagttcaca gagtacctgg aggatttcca tgtctggctg
5821 tcggtgtaca gcaggccctc ctccagccgc tacctgcaca cgccgcgcct caccgtgtcc
5881 ttctccctgc tgtgcgtcta cgcgtgtctc actgccctgg ttgctgctgg agggcaagag
5941 cagccccact tggacgtcag ccccaccctt ggatccttca gggtgggtct cctgtgtacc
6001 ctcctggctt ctccaggggc ccagctcttg tccctgctct tcaggctcag caaggaagcc
6061 ccggggtctg cccgagtgga gccacacagc ccacttagag gaggagcaca gaccgaggca
6121 ccccatggtc ctaattcctg gggaaggata ccagacgcac aggagccacg caagcaacct
6181 gcatcagcca ttctctctgg gagtggcagg gcccaaagga aggcggcaag tgacaatggc
6241 acagcttgtc cagcccctaa gctgcaggtt catggggctg accacagcag gacttctctg
6301 atggggaaaa gccactgctg ccctccccac actcaagcac ccagcagtgg tttggaggga
6361 ctaatgcccc agtggtcaag ggcccttcag ccttggtgga gctctgcagt gtgggccatt
6421 tgtgggaccg cttctttggc ctgcagtttg gggacaggat ttctagccta caggtttggc
6481 caggagcaat gtgtgcagtg gctgcacctg ctgtccctct ccgtggtctg ctgtattttc
6541 atcacccagc cacttatggt atgcctcatg gccttgggtt ttgcttggaa aagaagagct
6601 gacaaccact tttttactga gtctttatgt gaggctacca gggatctgga ctctgaattg
6661 gcagaacgtt cctggactcg cctccccttc tcttcaagct gcagtattcc tgactgtgca
6721 ggcgaggttg aaaaagtctt ggctgcccga caacaagctc gccacctgcg ctgggcgcat
6781 ccaccatcca aggcccagct gaggggcacc agacagagga tgaggagaga gagtcgcaca
6841 cgggctgccc tgagagacat ttccatggac atcctcatgc tgcttctgct tttgtgtgta
6901 atatatggga gattttccca agatgaatac tccctcaatc aagctatccg gaaagaattt
6961 acaagaaatg ccagaaactg cttgggtggc ctgagaaaca tcgctgactg gtgggactgg
7021 agtctgacca cacttctgga tggcctgtac ccgggaggca ccccgtcagc ccgtgtgccg
7081 ggggctcagc ctggagctct tggaggaaaa tgctacctaa taggcagttc cgtaattagg
7141 cagctaaaag tttttcctag gcatttatgc aagcctccca ggccattttc agcactcatc
7201 gaagactcta ttcctacatg tagtcccgaa gttggaggcc ctgagaaccc ctacctgata
7261 gacccagaga accaaaacgt gaccctgaat ggtcctgggg gctgtgggac aagggaggac
7321 tgtgtgctca gcctgggcag aacaaggact gaagcccaca cagccctgtc ccgactcagg
7381 gccagcatgt ggattgaccg cagcaccagg gctgtgtctg tgcacttcac tctctataac
7441 cctccaaccc aactcttcac cagcgtgtcc ctgagagtgg agatcctccc tacggggagt
7501 ctcgtcccct catccctggt ggagtcattc agcatcttcc gcagcgactc agccctgcag
7561 taccacctca tgcttcccca gctggtcttc ctggcactca gcctgatcca cctctgtgtt
7621 caactctacc gtatgatgga caagggcgtc ctcagctact ggcgaaagcc aaggaactgg
7681 ctggagctct ccgtggttgg agtgagcctc acctactatg cagtttccgg ccaccttgtt
7741 actcttgctg gagatgtcac taaccagttt cacagaggac tttgccgagc atttatggac
7801 ctcaccctta tggcatcatg gaatcagagg gctcgatggc tccggggaat cctcttattc
7861 ctcttcacat taaaatgcgt ctatcttcct ggcattcaaa acacaatggc atcctgctcc
7921 tccatgatgc gccactcact ccccagcatc tttgtagcag ggctggtggg ggcactgatg
7981 ctggccgccc tctcccacct gcaccgattt ctgctctcta tgtgggttct accacctggc
8041 accttcacag acgccttccc cgggctgctg tttcattttc ccagaagaag ccaaaaagac
8101 tgcctccttg gcctttccaa gtctgaccag cgggccatgg cttgttactt tgggatcctt
8161 ttaatagtct ctgccacact gtgttttgga atgctgagag gttttctcat gactttaccc
8221 caaaaaagaa aatcttttca aagtaaatct tttgtgagac ttaaagatgt cactgcttat
8281 atgtgggaaa aggtcctcac ctttctgaga ctggaaacac caaagttgga agaggctgag
8341 atggttgaga atcacaatta ctacttggat gaatttgcaa atctgttaga cgaacttctg
8401 atgaagatta atggtttgtc cgacagccta caactccccc ttctggaaaa aacatccaac
8461 aacacagggg aggcaaggac agaagagagt cccttagtgg acatttctag ttaccaagct
8521 gctgagccag cagacatcaa ggacttctga ggagcctggt accttgcata ggcactatgg
8581 accctgtttt gcttaaccca cccaacagcc aattttag
//