LOCUS AB055982 6786 bp mRNA linear HUM 18-AUG-2001
DEFINITION Homo sapiens ABCA1 mRNA for ABCA1, complete cds.
ACCESSION AB055982
VERSION AB055982.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6786)
AUTHORS Ueda,K., Kioka,N. and Tanaka,A.R.
TITLE Direct Submission
JOURNAL Submitted (20-FEB-2001) to the DDBJ/EMBL/GenBank databases.
Contact:Kazumitsu Ueda
Kyoto University Graduate School, Applied Life Sciences;
Kitashirakawa, Kyoto Sakyo-ku, Kyoto 606-8502, Japan
REFERENCE 2
AUTHORS Tanaka,A.R., Abe-Dohmae,S., Arakawa,R., Sadanami,K., Kidera,A.,
Kioka,N., Amachi,T., Yokoyama,S. and Ueda,K.
TITLE A new topological model of functional human ABCA1-Signal peptide
cleavage and glycosylation of a large extracellular domain
JOURNAL Unpublished (2001)
COMMENT
FEATURES Location/Qualifiers
source 1..6786
/db_xref="H-InvDB:HIT000059758"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 1..6786
/codon_start=1
/gene="ABCA1"
/product="ABCA1"
/protein_id="BAB63210.1"
/transl_table=1
/translation="MACWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRL
SYPPYEQHECHFPNKAMPSAGTLPWVQGIICNANNPCFRYPTPGEAPGVVGNFNKSIV
ARLFSDARRLLLYSQKDTSMKDMRKVLRTLQQIKKSSSNLKLQDFLVDNETFSGFLYH
NLSLPKSTVDKMLRADVILHKVFLQGYQLHLTSLCNGSKSEEMIQLGDQEVSELCGLP
REKLAAAERVLRSNMDILKPILRTLNSTSPFPSKELAEATKTLLHSLGTLAQELFSMR
SWSDMRQEVMFLTNVNSSSSSTQIYQAVSRIVCGHPEGGGLKIKSLNWYEDNNYKALF
GGNGTEEDAETFYDNSTTPYCNDLMKNLESSPLSRIIWKALKPLLVGKILYTPDTPAT
RQVMAEVNKTFQELAVFHDLEGMWEELSPKIWTFMENSQEMDLVRMLLDSRDNDHFWE
QQLDGLDWTAQDIVAFLAKHPEDVQSSNGSVYTWREAFNETNQAIRTISRFMECVNLN
KLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERT
NKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPY
PCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILW
FSWFISSLIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLF
SRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGFGCEYFALFE
EQGIGVQWDNLFESPVEEDGFNLTTSVSMMLFDTFLYGVMTWYIEAVFPGQYGIPRPW
YFPCTKSYWFGEESDEKSHPGSNQKRISEICMEEEPTHLKLGVSIQNLVKVYRDGMKV
AVDGLALNFYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIR
QNLGVCPQHNVLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKT
SQLSGGMQRKLSVALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKYRQGRTIILST
HHMDEADVLGDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSS
STVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHEL
TYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEESGVDAETS
DGTLPARRNRRAFGDKQSCLRPFTEDDAADPNDSDIDPESRETDLLSGMDGKGSYQVK
GWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLE
LQPWMYNEQYTFVSNDAPEDTGTLELLNALTKDPGFGTRCMEGNPIPDTPCQAGEEEW
TTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLPPPQRKQNTA
DILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNTQALPPSQEVN
DAIKQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNVKVWFNNKGWHAISSFLNVIN
NAILRANLQKGENPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFV
PASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQ
KSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVA
TFVLELFTDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVS
PLSWDLVGRNLFAMAVEGVVFFLITVLIQYRFFIRPRPVNAKLSPLNDEDEDVRRERQ
RILDGGGQNDILEIKELTKIYRRKRKPAVDRICVGIPPGECFGLLGVNGAGKSSTFKM
LTGDTTVTRGDAFLNKNSILSNIHEVHQNMGYCPQFDAITELLTGREHVEFFALLRGV
PEKEVGKVGEWAIRKLGLVKYGEKYAGNYSGGNKRKLSTAMALIGGPPVVFLDEPTTG
MDPKARRFLWNCALSVVKEGRSVVLTSHSMEECEALCTRMAIMVNGRFRCLGSVQHLK
NRFGDGYTIVVRIAGSNPDLKPVQDFFGLAFPGSVLKEKHRNMLQYQLPSSLSSLARI
FSILSQSKKRLHIEDYSVSQTTLDQVFVNFAKDQSDDDHLKDLSLHKNQTVVDVAVLT
SFLQDEKVKESYV"
BASE COUNT 1724 a 1643 c 1759 g 1660 t
ORIGIN
1 atggcttgtt ggcctcagct gaggttgctg ctgtggaaga acctcacttt cagaagaaga
61 caaacatgtc agctgctgct ggaagtggcc tggcctctat ttatcttcct gatcctgatc
121 tctgttcggc tgagctaccc accctatgaa caacatgaat gccattttcc aaataaagcc
181 atgccctctg caggaacact tccttgggtt caggggatta tctgtaatgc caacaacccc
241 tgtttccgtt acccgactcc tggggaggct cccggagttg ttggaaactt taacaaatcc
301 attgtggctc gcctgttctc agatgctcgg aggcttcttt tatacagcca gaaagacacc
361 agcatgaagg acatgcgcaa agttctgaga acattacagc agatcaagaa atccagctca
421 aacttgaagc ttcaagattt cctggtggac aatgaaacct tctctgggtt cctgtatcac
481 aacctctctc tcccaaagtc tactgtggac aagatgctga gggctgatgt cattctccac
541 aaggtatttt tgcaaggcta ccagttacat ttgacaagtc tgtgcaatgg atcaaaatca
601 gaagagatga ttcaacttgg tgaccaagaa gtttctgagc tttgtggcct accaagggag
661 aaactggctg cagcagagcg agtacttcgt tccaacatgg acatcctgaa gccaatcctg
721 agaacactaa actctacatc tcccttcccg agcaaggagc tggctgaagc cacaaaaaca
781 ttgctgcata gtcttgggac tctggcccag gagctgttca gcatgagaag ctggagtgac
841 atgcgacagg aggtgatgtt tctgaccaat gtgaacagct ccagctcctc cacccaaatc
901 taccaggctg tgtctcgtat tgtctgcggg catcccgagg gaggggggct gaagatcaag
961 tctctcaact ggtatgagga caacaactac aaagccctct ttggaggcaa tggcactgag
1021 gaagatgctg aaaccttcta tgacaactct acaactcctt actgcaatga tttgatgaag
1081 aatttggagt ctagtcctct ttcccgcatt atctggaaag ctctgaagcc gctgctcgtt
1141 gggaagatcc tgtatacacc tgacactcca gccacaaggc aggtcatggc tgaggtgaac
1201 aagaccttcc aggaactggc tgtgttccat gatctggaag gcatgtggga ggaactcagc
1261 cccaagatct ggaccttcat ggagaacagc caagaaatgg accttgtccg gatgctgttg
1321 gacagcaggg acaatgacca cttttgggaa cagcagttgg atggcttaga ttggacagcc
1381 caagacatcg tggcgttttt ggccaagcac ccagaggatg tccagtccag taatggttct
1441 gtgtacacct ggagagaagc tttcaacgag actaaccagg caatccggac catatctcgc
1501 ttcatggagt gtgtcaacct gaacaagcta gaacccatag caacagaagt ctggctcatc
1561 aacaagtcca tggagctgct ggatgagagg aagttctggg ctggtattgt gttcactgga
1621 attactccag gcagcattga gctgccccat catgtcaagt acaagatccg aatggacatt
1681 gacaatgtgg agaggacaaa taaaatcaag gatgggtact gggaccctgg tcctcgagct
1741 gacccctttg aggacatgcg gtacgtctgg gggggcttcg cctacttgca ggatgtggtg
1801 gagcaggcaa tcatcagggt gctgacgggc accgagaaga aaactggtgt ctatatgcaa
1861 cagatgccct atccctgtta cgttgatgac atctttctgc gggtgatgag ccggtcaatg
1921 cccctcttca tgacgctggc ctggatttac tcagtggctg tgatcatcaa gggcatcgtg
1981 tatgagaagg aggcacggct gaaagagacc atgcggatca tgggcctgga caacagcatc
2041 ctctggttta gctggttcat tagtagcctc attcctcttc ttgtgagcgc tggcctgcta
2101 gtggtcatcc tgaagttagg aaacctgctg ccctacagtg atcccagcgt ggtgtttgtc
2161 ttcctgtccg tgtttgctgt ggtgacaatc ctgcagtgct tcctgattag cacactcttc
2221 tccagagcca acctggcagc agcctgtggg ggcatcatct acttcacgct gtacctgccc
2281 tacgtcctgt gtgtggcatg gcaggactac gtgggcttca cactcaagat cttcgctagc
2341 ctgctgtctc ctgtggcttt tgggtttggc tgtgagtact ttgccctttt tgaggagcag
2401 ggcattggag tgcagtggga caacctgttt gagagtcctg tggaggaaga tggcttcaat
2461 ctcaccactt cggtctccat gatgctgttt gacaccttcc tctatggggt gatgacctgg
2521 tacattgagg ctgtctttcc aggccagtac ggaattccca ggccctggta ttttccttgc
2581 accaagtcct actggtttgg cgaggaaagt gatgagaaga gccaccctgg ttccaaccag
2641 aagagaatat cagaaatctg catggaggag gaacccaccc acttgaagct gggcgtgtcc
2701 attcagaacc tggtaaaagt ctaccgagat gggatgaagg tggctgtcga tggcctggca
2761 ctgaattttt atgagggcca gatcacctcc ttcctgggcc acaatggagc ggggaagacg
2821 accaccatgt caatcctgac cgggttgttc cccccgacct cgggcaccgc ctacatcctg
2881 ggaaaagaca ttcgctctga gatgagcacc atccggcaga acctgggggt ctgtccccag
2941 cataacgtgc tgtttgacat gctgactgtc gaagaacaca tctggttcta tgcccgcttg
3001 aaagggctct ctgagaagca cgtgaaggcg gagatggagc agatggccct ggatgttggt
3061 ttgccatcaa gcaagctgaa aagcaaaaca agccagctgt caggtggaat gcagagaaag
3121 ctatctgtgg ccttggcctt tgtcggggga tctaaggttg tcattctgga tgaacccaca
3181 gctggtgtgg acccttactc ccgcagggga atatgggagc tgctgctgaa ataccgacaa
3241 ggccgcacca ttattctctc tacacaccac atggatgaag cggacgtcct gggggacagg
3301 attgccatca tctcccatgg gaagctgtgc tgtgtgggct cctccctgtt tctgaagaac
3361 cagctgggaa caggctacta cctgaccttg gtcaagaaag atgtggaatc ctccctcagt
3421 tcctgcagaa acagtagtag cactgtgtca tacctgaaaa aggaggacag tgtttctcag
3481 agcagttctg atgctggcct gggcagcgac catgagagtg acacgctgac catcgatgtc
3541 tctgctatct ccaacctcat caggaagcat gtgtctgaag cccggctggt ggaagacata
3601 gggcatgagc tgacctatgt gctgccatat gaagctgcta aggagggagc ctttgtggaa
3661 ctctttcatg agattgatga ccggctctca gacctgggca tttctagtta tggcatctca
3721 gagacgaccc tggaagaaat attcctcaag gtggccgaag agagtggggt ggatgctgag
3781 acctcagatg gtaccttgcc agcaagacga aacaggcggg ccttcgggga caagcagagc
3841 tgtcttcgcc cgttcactga agatgatgct gctgatccaa atgattctga catagaccca
3901 gaatccagag agacagactt gctcagtggg atggatggca aagggtccta ccaggtgaaa
3961 ggctggaaac ttacacagca acagtttgtg gcccttttgt ggaagagact gctaattgcc
4021 agacggagtc ggaaaggatt ttttgctcag attgtcttgc cagctgtgtt tgtctgcatt
4081 gcccttgtgt tcagcctgat cgtgccaccc tttggcaagt accccagcct ggaacttcag
4141 ccctggatgt acaacgaaca gtacacattt gtcagcaatg atgctcctga ggacacggga
4201 accctggaac tcttaaacgc cctcaccaaa gaccctggct tcgggacccg ctgtatggaa
4261 ggaaacccaa tcccagacac gccctgccag gcaggggagg aagagtggac cactgcccca
4321 gttccccaga ccatcatgga cctcttccag aatgggaact ggacaatgca gaacccttca
4381 cctgcatgcc agtgtagcag cgacaaaatc aagaagatgc tgcctgtgtg tcccccaggg
4441 gcaggggggc tgcctcctcc acaaagaaaa caaaacactg cagatatcct tcaggacctg
4501 acaggaagaa acatttcgga ttatctggtg aagacgtatg tgcagatcat agccaaaagc
4561 ttaaagaaca agatctgggt gaatgagttt aggtatggcg gcttttccct gggtgtcagt
4621 aatactcaag cacttcctcc gagtcaagaa gttaatgatg ccatcaaaca aatgaagaaa
4681 cacctaaagc tggccaagga cagttctgca gatcgatttc tcaacagctt gggaagattt
4741 atgacaggac tggacaccaa aaataatgtc aaggtgtggt tcaataacaa gggctggcat
4801 gcaatcagct ctttcctgaa tgtcatcaac aatgccattc tccgggccaa cctgcaaaag
4861 ggagagaacc ctagccatta tggaattact gctttcaatc atcccctgaa tctcaccaag
4921 cagcagctct cagaggtggc tctgatgacc acatcagtgg atgtccttgt gtccatctgt
4981 gtcatctttg caatgtcctt cgtcccagcc agctttgtcg tattcctgat ccaggagcgg
5041 gtcagcaaag caaaacacct gcagttcatc agtggagtga agcctgtcat ctactggctc
5101 tctaattttg tctgggatat gtgcaattac gttgtccctg ccacactggt cattatcatc
5161 ttcatctgct tccagcagaa gtcctatgtg tcctccacca atctgcctgt gctagccctt
5221 ctacttttgc tgtatgggtg gtcaatcaca cctctcatgt acccagcctc ctttgtgttc
5281 aagatcccca gcacagccta tgtggtgctc accagcgtga acctcttcat tggcattaat
5341 ggcagcgtgg ccacctttgt gctggagctg ttcaccgaca ataagctgaa taatatcaat
5401 gatatcctga agtccgtgtt cttgatcttc ccacattttt gcctgggacg agggctcatc
5461 gacatggtga aaaaccaggc aatggctgat gccctggaaa ggtttgggga gaatcgcttt
5521 gtgtcaccat tatcttggga cttggtggga cgaaacctct tcgccatggc cgtggaaggg
5581 gtggtgttct tcctcattac tgttctgatc cagtacagat tcttcatcag gcccagacct
5641 gtaaatgcaa agctatctcc tctgaatgat gaagatgaag atgtgaggcg ggaaagacag
5701 agaattcttg atggtggagg ccagaatgac atcttagaaa tcaaggagtt gacgaagata
5761 tatagaagga agcggaagcc tgctgttgac aggatttgcg tgggcattcc tcctggtgag
5821 tgctttgggc tcctgggagt taatggggct ggaaaatcat caactttcaa gatgttaaca
5881 ggagatacca ctgttaccag aggagatgct ttccttaaca aaaatagtat cttatcaaac
5941 atccatgaag tacatcagaa catgggctac tgccctcagt ttgatgccat cacagagctg
6001 ttgactggga gagaacacgt ggagttcttt gcccttttga gaggagtccc agagaaagaa
6061 gttggcaagg ttggtgagtg ggcgattcgg aaactgggcc tcgtgaagta tggagaaaaa
6121 tatgctggta actatagtgg aggcaacaaa cgcaagctct ctacagccat ggctttgatc
6181 ggcgggcctc ctgtggtgtt tctggatgaa cccaccacag gcatggatcc caaagcccgg
6241 cggttcttgt ggaattgtgc cctaagtgtt gtcaaggagg ggagatcagt agtgcttaca
6301 tctcatagta tggaagagtg tgaagctctt tgcactagga tggcaatcat ggtcaatgga
6361 aggttcaggt gccttggcag tgtccagcat ctaaaaaata ggtttggaga tggttataca
6421 atagttgtac gaatagcagg gtccaacccg gacctgaagc ctgtccagga tttctttgga
6481 cttgcatttc ctggaagtgt tctaaaagag aaacaccgga acatgctaca ataccagctt
6541 ccatcttcat tatcttctct ggccaggata ttcagcatcc tctcccagag caaaaagcga
6601 ctccacatag aagactactc tgtttctcag acaacacttg accaagtatt tgtgaacttt
6661 gccaaggacc aaagtgatga tgaccactta aaagacctct cattacacaa aaaccagaca
6721 gtagtggacg ttgcagttct cacatctttt ctacaggatg agaaagtgaa agaaagctat
6781 gtatga
//