LOCUS AB053309 3438 bp mRNA linear HUM 05-OCT-2001
DEFINITION Homo sapiens ALS2CR8 mRNA, complete cds, long form.
ACCESSION AB053309
VERSION AB053309.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3438)
AUTHORS Hadano,S. and Ikeda,J.
TITLE Direct Submission
JOURNAL Submitted (08-JAN-2001) to the DDBJ/EMBL/GenBank databases.
Contact:Shinji Hadano
Tokai University, The Institute of Medical Sciences; Bohseidai,
Isehara, Kanagawa 259-1193, Japan
REFERENCE 2
AUTHORS Hadano,S., Hand,C.K., Osuga,H., Yanagisawa,Y., Otomo,A.,
Devon,R.S., Miyamoto,N., Showguchi-Miyata,J., Okada,Y.,
Singaraja,R., Figlewicz,D.A., Kwiatkowski,T., Hosler,B.A.,
Sagie,T., Skaug,J., Nasir,J., Brown,R.H.,Jr., Scherer,S.W.,
Rouleau,G.A., Hayden,M.R. and Ikeda,J.-E.
TITLE A gene encoding a novel GTPase regulator is mutated in familial
amyotrophic lateral sclerosis 2
JOURNAL Nat. Genet. 29, 166-173 (2001)
COMMENT
FEATURES Location/Qualifiers
source 1..3438
/chromosome="2"
/clone="CALS139L"
/db_xref="H-InvDB:HIT000059679"
/db_xref="taxon:9606"
/map="2q33"
/mol_type="mRNA"
/note="alternative splicing variant, long form, see also
AB053310"
/note="clone:IMAGE:1376470:369-3438nt"
/note="clone:IMAGE:3078066:1-1073nt"
/note="composite sequence:1-3438nt"
/organism="Homo sapiens"
CDS 698..2854
/codon_start=1
/gene="ALS2CR8"
/note="long form"
/protein_id="BAB69018.1"
/transl_table=1
/translation="MEQSNDSLRVNHNDGEESKTSAQVFEHLICMDSRDSSFGQNDSP
TVLPITTREANNSLISQNIPGPLTQTQTLSAEQFHLVDQNGQAIQYELQSLGESNAQM
MIVASPTENGQVLRVIPPTQTGMAQVIIPQGQLVDVNSPRDVPEEKPSNRNLPTVRVD
TLADNTSNYILHPQTSFPLPKKSVTGMLEEPLLGPLQPLSSNTPIWACRLRSCEKIGD
SYRGYCVSETELESVLTFHKQQTQSVWGTRQSPSPAKPATRLMWKSQYVPYDGIPFVN
AGSRAVVMECQYGPRRKGFQLKKVSEQESRSCQLYKATCPARIYIKKVQKFPEYRVPT
DPKIDKKIIRMEQEKAFNMLKKNLVDAGGVLRWYVQLPTQQAHQYHELETPCLTLSPS
PFPVSSLEEEETAVRDENCALPSRLHPQVAHKIQELVSQGIEQVYAVRKQLRKFVERE
LFKPDEVPERHNLSFFPTVNDIKNHIHEVQKSLRNGDTVYNSEIIPATLQWTTDSGNI
LKETMTVTFAEGNSPGESITTKVETNQTRGSLSPEPTHLLSSLSSFQPKIFTQLQGLQ
LQPRYTSPDESPAVVSVNNQPSSSPSGLLDTIGSAVMNNNSLLLGQSHSLQRDTCLTQ
NNSTASTMGNLPEPDQNLVAMDELVEVGDVEDTGNLEGTVHRILLGDVQTIPIQIIDN
HSALIEENPESTISVSQVKQEPKEPALSMEAKNCGL"
BASE COUNT 1090 a 688 c 691 g 969 t
ORIGIN
1 gccgcggaga aggagccgga ccccttgggc ggagcgccca atgtgtggtc cctcacgccg
61 tcccgcacct tgctttttag ggttcttttt ccgctttctg agccctttta taccttacgt
121 ttagaagggg aaaatcatcc tcccacacct tctccccgac tttttgcctt ttttgtcttg
181 aagttaccca aaggcctgtg tattgttctc aatggtccca agaattactc taatatagtt
241 gtttttctga gggaggatgg atggagataa ctatcctgat cccaatgtca ctttttaagg
301 cattcgcttc aagagacaag cagtttagaa tcaggcagaa ctggattgca aaatttatgg
361 gcagaccgag aaaatgctgc tgtgaagacc caattaaagc tttcacataa atgaagctac
421 agctatcatg atttagtgcc cccaaaagga agaacttcag tggacaagaa aggacatttc
481 tgggggtagt agaatgcttg aggcctggaa tttaaacctg agccactatc tgaaggttta
541 atatatcttt gccaagtcca agggtacaaa gattttctcc tgtgttttct tctagaagtt
601 ttatcatttg atagtctgtg atccatttca agttgatttg ctatctggtg tgagctatta
661 aataatagaa gaaaatggaa ttgaatatga tgtcagcatg gaacaatcta atgattcatt
721 aagagtcaac cataatgacg gtgaagagtc aaaaaccagt gctcaagtat ttgagcatct
781 aatctgtatg gactccaggg attcttcctt tggacaaaat gattctccta cagttttgcc
841 catcactact cgtgaagcaa ataattcact catatcacag aatataccag ggcccctgac
901 tcagacacag actctttctg cagagcaatt ccatctagtg gaccaaaatg ggcaggctat
961 tcaatatgaa cttcagtcat tgggggaatc caatgcacaa atgatgatcg ttgccagccc
1021 aacagaaaat ggacaggtac ttcgtgtaat tccacctacc cagacaggaa tggcacaagt
1081 gattatacct caggggcaac ttgtggatgt gaatagtcct cgggatgtcc ctgaagagaa
1141 acccagtaac agaaacttac caactgtaag agtggatact ctagcagaca ataccagcaa
1201 ttacattctt catcctcaaa catccttccc attgcccaaa aagtcagtga ccggaatgct
1261 ggaagaaccc cttctggggc ctcttcagcc actttcttct aatacaccta tatgggcctg
1321 ccgtcttagg agctgtgaga aaattggaga ttcataccgt ggctactgtg taagtgagac
1381 tgaattagaa agtgtcctaa catttcacaa gcagcaaaca cagagtgttt gggggacccg
1441 tcagtctcca agcccagcca agcctgctac acgcttgatg tggaaatccc agtatgttcc
1501 atatgatgga atcccatttg ttaatgcagg gagtagagct gtggtaatgg agtgtcagta
1561 tgggccaaga agaaaaggtt tccagttaaa aaaagtcagt gagcaggaaa gcaggtcttg
1621 tcagctctac aaagccactt gtccagctcg gatttacatt aaaaaggtac agaagtttcc
1681 tgaatataga gttcctacag accccaaaat tgacaagaaa attatcagaa tggagcagga
1741 gaaagctttt aacatgctaa agaagaactt ggtagatgct ggtggtgttc ttaggtggta
1801 tgtacagtta cctacacagc aagctcatca gtatcatgaa ttagagactc cctgcctcac
1861 tttgtcacct tctccttttc ctgtgtcttc tcttgaagaa gaggaaactg cagttagaga
1921 tgagaattgt gcattaccct cacgtttaca tcctcaagta gcacataaga ttcaagaatt
1981 agtatcacag ggaatagaac aagtgtatgc agtaaggaaa cagctaagaa aatttgtgga
2041 aagggaactg ttcaaacccg atgaggtacc tgaaagacat aatttatctt tttttccaac
2101 tgtaaatgat ataaaaaatc acatccatga ggtacagaaa tccttgagaa atggagatac
2161 ggtatataac tcagagatta ttccagcaac gcttcaatgg actacagaca gtgggaatat
2221 tctcaaagag accatgacag ttacatttgc agaaggaaat tcaccaggag aatcaattac
2281 caccaaagtg gaaacaaatc agaccagggg ttctttgtct cctgagccaa cccacttgct
2341 ctcctcactc tcctcatttc agcccaaaat atttacacaa ctacagggtt tgcagttaca
2401 accaaggtac acctctcctg atgaatcacc agctgtggta tcagtaaata accagccgtc
2461 ctctagtcct tcaggacttc tggatacaat aggaagtgct gtaatgaata ataattctct
2521 actgcttggt caaagtcata gccttcaaag agatacatgc ttaacccaaa acaatagtac
2581 tgcctccacc atgggtaacc ttccagaacc agatcaaaat ctagttgcaa tggacgagct
2641 ggtagaagtt ggagatgttg aggatacagg gaatctggaa ggaactgttc atcggattct
2701 gttgggagat gtgcagacta ttccaataca gattatagac aaccactcag ctcttattga
2761 agaaaatcca gaaagtacca tttctgtgag ccaagttaaa caagaaccca aagaaccagc
2821 attgtctatg gaagcaaaaa actgtggact ataagaaatt atctgctaca taaattattg
2881 aagcttttca gaatttacaa ctctggtgac ttctgatgtc ttagaaagga aggtgaatat
2941 agtcaaagcg tggcattgag ataattggac tgaagaccag tttgatgaga agcttttatt
3001 taaaactgat atatttgttg ccagttccat atttttacct tccttaagag atgttttact
3061 cttcttattt tgtataattt ttatgctctt tgattatcta ataaggccag tatttcaaaa
3121 gctgttctga atttatccac agtaatatag tctgaacaca aatagtttac ttaacttatc
3181 cttggaaata ttcaattttg gttattacaa aacagaaaag aacaacagca acaaaaacat
3241 tgtgtgaata tatgtttgta tgtgtgtatg tatatcatga attttttttt taagttctga
3301 aaaagaactt gttctctcct taaagttgtg aagaaattgt taattgccag acaggtaaga
3361 aaatgtttat aatctatctc attaagaaag atgaagtatt agattttaca tcataacaca
3421 aagtccagca gctacatc
//