LOCUS AB050468 5287 bp mRNA linear HUM 12-JAN-2006
DEFINITION Homo sapiens lig-1 mRNA for membrane glycoprotein LIG-1, complete
cds.
ACCESSION AB050468
VERSION AB050468.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5287)
AUTHORS Suzuki,Y.
TITLE Direct Submission
JOURNAL Submitted (23-OCT-2000) to the DDBJ/EMBL/GenBank databases.
Contact:Yutaka Suzuki
Tanabe Seiyaku Co., Ltd., Discovery Research Laboratory; Kashima
3-16-89, Yodogawa-ku, Osaka, Osaka 532-8505, Japan
REFERENCE 2
AUTHORS Suzuki,Y., Miura,H., Tanemura,A., Kobayashi,K., Kondoh,G.,
Sano,S., Ozawa,K., Inui,S., Nakata,A., Takagi,T., Tohyama,M.,
Yoshikawa,K. and Itami,S.
TITLE Targeted disruption of LIG-1 gene results in psoriasiform
epidermal hyperplasia
JOURNAL FEBS Lett. 521, 67-71 (2002)
COMMENT
FEATURES Location/Qualifiers
source 1..5287
/db_xref="H-InvDB:HIT000059559"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 520..3804
/codon_start=1
/gene="lig-1"
/product="membrane glycoprotein LIG-1"
/protein_id="BAB40659.1"
/transl_table=1
/translation="MARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAA
CTCAGDSLDCGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNN
ELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFP
HGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDL
NRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNS
GSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLS
VLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGN
KIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKW
LPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLKPQIITQPETTMAMV
GKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQ
VTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTMARLECAATG
HPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGSIS
ANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHH
LTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAAGCRKDGTTVGIFTI
AVVSSIVLTSLVWVCIIYQTRKKSEEYSVTNTDETVVPPDVPSYLSSQGTLSDRQETV
VRTEGAGPQANGHIESNGVCPRDASHFPEPDTHSVACRQPKLCAGSAYHKEPWKAIEK
AEGTPGPHKMEHGGRVVCSDCNTEVDCYSRGQAFHPQPVSRDSAQPSAPNGPEPGGSD
QEHSPHHQCSRTAAGSCPECQGSLYPSNHDRMLTAVKKKPMASLDGKGDSSWTLARLY
HPDSTELQPASSLTSGSPERAEAQYLLVSNGHLPKACDASPESTPLTGQLPGKQRVPL
LLAPKS"
regulatory 5246..5251
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1245 a 1411 c 1469 g 1162 t
ORIGIN
1 ctggccgcgg cgtggggaca gcgaggcgca ctggggcctc ccagcgccgg gccggccgcg
61 ccgtccagcc cgaggtctac ggctttgcgc tccgagccca gaggaagatg cctgccggca
121 ccgagctcgg gctgcggggc tgaacgcctg tcttccaggc gcacggcagc actgccctcg
181 gccggtgtcg gtagcggcac tcggcgtgcc ccgggcggac gaagagcgca ggctgggtac
241 accttgcccg aatcggcgga gttcgcagct agcgagggcg ggccggccgg cccggatggg
301 cgcggggttt gcggcccccg ccgggtgctc cggagcggcc cgggcaccgg gggcacgctg
361 agtgccggag ccgcggccgc agagagaact tggggcgggg gccatgcacc ggtgcggagt
421 ctagagccga gcggagcgcc ccgcgggccc gcccgcgtct gcggccgttc gggtcctcac
481 agtccccgcg cccggagttc gcagcgcgct ccagacaaga tggcgcggcc ggtccgggga
541 gggctcgggg ccccgcgccg ctcgccttgc cttctccttc tctggctgct tttgcttcgg
601 ctggagccgg tgaccgccgc ggccggcccg cgggcgccct gcgcggccgc ctgcacttgc
661 gctggggact cgctggactg cggtgggcgc gggctggctg cgttgcccgg ggacctgccc
721 tcctggacgc ggagcctaaa cctgagttac aacaaactct ctgagattga ccctgctggt
781 tttgaggact tgccgaacct acaggaagtg tacctcaata ataatgagtt gacagcggta
841 ccatccctgg gcgctgcttc atcacatgtc gtctctctct ttctgcagca caacaagatt
901 cgcagcgtgg aggggagcca gctgaaggcc tacctttcct tagaagtgtt agatctgagt
961 ttgaacaaca tcacggaagt gcggaacacc tgctttccac acggaccgcc tataaaggag
1021 ctcaacctgg caggcaatcg gattggcacc ctggagttgg gagcatttga tggtctgtca
1081 cggtcgctgc taactcttcg cctgagcaaa aacaggatca cccagcttcc tgtaagagca
1141 ttcaagctac ccaggctgac acaactggac ctcaatcgga acaggattcg gctgatagag
1201 ggcctcacct tccaggggct caacagcttg gaggtgctga agcttcagcg aaacaacatc
1261 agcaaactga cagatggggc cttctgggga ctgtccaaga tgcatgtgct gcacctggag
1321 tacaacagcc tggtagaagt gaacagcggc tcgctctacg gcctcacggc cctgcatcag
1381 ctccacctca gcaacaattc catcgctcgc attcaccgca agggctggag cttctgccag
1441 aagctgcatg agttggtcct gtccttcaac aacctgacac ggctggacga ggagagcctg
1501 gccgagctga gcagcctgag tgtcctgcgt ctcagccaca attccatcag ccacattgcg
1561 gagggtgcct tcaagggact caggagcctg cgagtcttgg atctggacca taacgagatt
1621 tcgggcacaa tagaggacac gagcggcgcc ttctcagggc tcgacagcct cagcaagctg
1681 actctgtttg gaaacaagat caagtctgtg gctaagagag cattctcggg gctggaaggc
1741 ctggagcacc tgaaccttgg agggaatgcg atcagatctg tccagtttga tgcctttgtg
1801 aagatgaaga atcttaaaga gctccatatc agcagcgaca gcttcctgtg tgactgccag
1861 ctgaagtggc tgcccccgtg gctaattggc aggatgctgc aggcctttgt gacagccacc
1921 tgtgcccacc cagaatcact gaagggtcag agcattttct ctgtgccacc agagagtttc
1981 gtgtgcgatg acttcctgaa gccacagatc atcacccagc cagaaaccac catggctatg
2041 gtgggcaagg acatccggtt tacatgctca gcagccagca gcagcagctc ccccatgacc
2101 tttgcctgga agaaagacaa tgaagtcctg accaatgcag acatggagaa ctttgtccac
2161 gtccacgcgc aggacgggga agtgatggag tacaccacca tcctgcacct ccgtcaggtc
2221 actttcgggc acgagggccg ctaccaatgt gtcatcacca accactttgg ctccacctat
2281 tcacataagg ccaggctcac tgtgaatgtg ttgccatcat tcaccaaaac gccccacgac
2341 ataaccatcc ggaccaccac catggcccgc ctcgaatgtg ctgccacagg tcacccaaac
2401 cctcagattg cctggcagaa ggatggaggc acggatttcc ccgctgcccg tgagcgacgc
2461 atgcatgtca tgccggatga cgacgtgttt ttcatcactg atgtgaaaat agatgacgca
2521 ggggtttaca gctgtactgc tcagaactca gccggttcta tttcagctaa tgccaccctg
2581 actgtcctag agaccccatc cttggtggtc cccttggaag accgtgtggt atctgtggga
2641 gaaacagtgg ccctccaatg caaagccacg gggaaccctc cgccccgcat cacctggttc
2701 aagggggacc gcccgctgag cctcactgag cggcaccacc tgacccctga caaccagctc
2761 ctggtggttc agaacgtggt ggcagaggat gcgggccgat atacctgtga gatgtccaac
2821 accctgggca cggagcgagc tcacagccag ctgagcgtcc tgcccgcagc aggctgcagg
2881 aaggatggga ccacggtagg catcttcacc attgctgtcg tgagcagcat cgtcctgacg
2941 tcactggtct gggtgtgcat catctaccag accaggaaga agagtgaaga gtacagtgtc
3001 accaacacag atgaaaccgt cgtgccacca gatgttccaa gctacctctc ttctcagggg
3061 accctttctg accgacaaga aaccgtggtc aggaccgagg gtgcgggccc tcaggccaat
3121 gggcacattg agagcaatgg tgtgtgtcca agagatgcaa gccactttcc agagcccgac
3181 actcacagcg ttgcctgcag gcagccaaag ctctgtgctg ggtctgcgta tcacaaagag
3241 ccgtggaaag cgattgagaa agctgaaggg acacctgggc cacataagat ggaacacggt
3301 ggccgggtcg tatgcagtga ctgcaacacc gaagtggact gttactccag gggacaagcc
3361 ttccaccccc agcctgtgtc cagagacagc gcacagccaa gtgcgccaaa tggcccggag
3421 ccgggtggga gtgaccaaga gcattctcca catcaccagt gcagcaggac tgccgctggg
3481 tcctgccccg agtgccaagg gtcgctctac cccagtaacc acgatagaat gctgacggct
3541 gtgaagaaaa agccaatggc atctctagat gggaaagggg attcttcctg gactttagca
3601 aggttgtatc acccggactc tacagagcta cagcctgcat cttcattaac ttcaggcagt
3661 ccagagcgcg cggaagccca gtacttgctt gtttccaatg gccacctccc caaagcatgt
3721 gacgccagtc ccgagtccac gccactgaca ggacagctcc ccgggaaaca gagggtgcca
3781 ctgctgttgg caccaaaaag ctaggttttg tctacctcag ttcttgtcat accaatctct
3841 acgggaaaga gaggtaggag aggctgcgag gaagcttggg ttcaagcgtc actcatctgt
3901 acatagttgt aactcccatg tggagtatca gtcgctcaca ggacttggat ctgaagcaca
3961 gtaaacgcaa gaggggattt gtgtacaaaa ggcaaaaaaa gtatttgata tcattgtaca
4021 taagagtttt cagagatttc atatatatct tttacagagg ctattttaat ctttagtgca
4081 tggttaacag aaaaaaatta tacaattttg acaatattat ttttcgtatc aggttgctgt
4141 ttaattttgg agggggtggg gaaatagttc tggtgcctta acgcatggct ggaatttata
4201 gaggctacaa ccacatttgt tcacaggagt ttttggtgcg ggtggggaag gatggaaggc
4261 cttggattta tattgcactt catagacccc taggctgctg tgcggtggga ctccacatgc
4321 gccggaagga gcttcaggtg agcactgctc atgtgtggat gcccctgcaa caggcttccc
4381 tgtctgtaga gccaggggtg caagtgccat ccacacttgc agtgaatggc ttttcctttt
4441 aggtttaagt cctgtctgtc tgtaaggcgt agaatctgtc cgtctgtaag gcgtagaatg
4501 agggttgtta atccatcaca agcaaaaggt cagaacagtt aaacactgcc tttcctcctc
4561 ctcttatttt atgataaaag caaatgtggc cttctcagta tcattcgatt gctatttgag
4621 acttttaaat taaggtaaag gctgctggtg ttggtacctg tggatttttc tatactgatg
4681 ttttcgtttt gccaatataa tgagtattac attggccttg ggggacagaa aggaggaagt
4741 tctgactttt cagggctacc ttatttctac taaggaccca gagcaggcct gtccatgcca
4801 ttccttcgca cagatgaaac tgagctggga ctggaaagga cagcccttga cctgggttct
4861 gggtataatt tgcacttttg agactggtag ctaaccatct tatgagtgcc aatgtgtcat
4921 ttagtaaaac ttaaatagaa acaaggtcct tcaaatgttc ctttggccaa aagctgaagg
4981 gagttactga gaaaatagtt aacaattact gtcaggtgtc atcactgttc aaaaggtaag
5041 cacatttaga attttgttct tgacagttaa ctgactaatc ttacttccac aaaatatgtg
5101 aatttgctgc ttctgagagg caatgtgaaa gagggagtat tacttttatg tacaaagtta
5161 tttatttata gaaattttgg tacagtgtac attgaaaacc atgtaaaata ttgaagtgtc
5221 taacaaatgg cattgaagtg tctttaataa aggttcattt ataaatgtca aaaaaaaaaa
5281 aaaaaaa
//