LOCUS AB049127 3609 bp mRNA linear HUM 10-APR-2001
DEFINITION Homo sapiens MARKL1 mRNA for MAP/microtubule affinity-regulating
kinase like 1, complete cds.
ACCESSION AB049127
VERSION AB049127.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3609)
AUTHORS Nakamura,Y., Furukawa,Y. and Kato,T.
TITLE Direct Submission
JOURNAL Submitted (20-SEP-2000) to the DDBJ/EMBL/GenBank databases.
Contact:Yoichi Furukawa
The University of Tokyo, Institute of Medical Science, Human
Genome Center; 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639,
Japan
REFERENCE 2
AUTHORS Kato,T., Satoh,S., Okabe,H., Kitahara,O., Ono,K., Kihara,C.,
Tanaka,T., Tsunoda,T., Yamaoka,Y., Nakamura,Y. and Furukawa,Y.
TITLE Isolation of a novel human gene, MARKL1, homologous to MARK3 and
its involvement in hepatocellular carcinogenesis
JOURNAL Neoplasia 3, 4-9 (2001)
COMMENT
FEATURES Location/Qualifiers
source 1..3609
/chromosome="19"
/db_xref="H-InvDB:HIT000059505"
/db_xref="taxon:9606"
/map="19q13.2"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="brain"
CDS 298..2364
/codon_start=1
/gene="MARKL1"
/product="MAP/microtubule affinity-regulating kinase like
1"
/protein_id="BAB39380.1"
/transl_table=1
/translation="MSSRTVLAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRN
SIASCPEEQPHVGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQK
LFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARA
KFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGS
PPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVP
FYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKR
IEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGDRGAPGLALARVRAPSD
TTNGTSSSKGTSHSKGQRSSSSTYHRQRRHSDFCGPSPAPLHPKRSPTSTGEAELKEE
RLPGRKASCSTAGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPPSMMTR
RNTYVCTERPGAERPSLLPNGKENSSGTPRVPPASPSSHSLAPPSGERSRLARGSTIR
STFHGGQVRDRRAGGGGGGGVQNGPPASPTLAHEAAPLPAGRPRPTTNLFTKLTSKLT
RRVTLDPSKRQNSNRCVSGASLPQGSKIRSQTNLRESGDLRSQVAIYLGIKRKPPPGC
SDSPGV"
BASE COUNT 726 a 1217 c 1046 g 619 t
ORIGIN
1 cgcctccctc cgccgccgct tgggccggct ccgcgccccc tccgcggccc ccgcccgccc
61 gcctgcccgc cgcccccatg gcgcccgggg tccccgctgc acggggccac taggaccctc
121 ggcgtccctt cccctccccc gccctgcccc ctctcccgcc gcgcggaccc gggcgttctc
181 ggcgcccagc ttttgagctc gcgtccccag gccggcgggg ggggagggga agagagggga
241 ccctgggacc cccgcccccc ccacccggcc gcccctgccc cccgggaccc ggagaagatg
301 tcttcgcgga cggtgctggc cccgggcaac gatcggaact cggacacgca tggcaccttg
361 ggcagtggcc gctcctcgga caaaggcccg tcctggtcca gccgctcact gggtgcccgt
421 tgccggaact ccatcgcctc ctgtcccgag gagcagcccc acgtgggcaa ctaccgcctg
481 ctgaggacca ttgggaaggg caactctgcc aaagtcaagc tggctcggca catcctcact
541 ggtcgggagg ttgccatcaa gattatcgac aaaacccagc tgaatcccag cagcctgcag
601 aagctgttcc gagaagtccg catcatgaag ggcctaaacc accccaacat cgtgaagctc
661 tttgaggtga ttgagactga gaagacgctg tacctggtga tggagtacgc aagtgctgga
721 gaagtgtttg actacctcgt gtcgcatggc cgcatgaagg agaaggaagc tcgagccaag
781 ttccgacaga ttgtttcggc tgtgcactat tgtcaccaga aaaatattgt acacagggac
841 ctgaaggctg agaacctctt gctggatgcc gaggccaaca tcaagattgc tgactttggc
901 ttcagcaacg agttcacgct gggatcgaag ctggacacgt tctgcgggag ccccccatat
961 gccgccccgg agctgtttca gggcaagaag tacgacgggc cggaggtgga catctggagc
1021 ctgggagtca tcctgtacac cctcgtcagc ggctccctgc ccttcgacgg gcacaacctc
1081 aaggagctgc gggagcgagt actcagaggg aagtaccggg tccctttcta catgtcaaca
1141 gactgtgaga gcatcctgcg gagatttttg gtgctgaacc cagctaaacg ctgtactctc
1201 gagcaaatca tgaaagacaa atggatcaac atcggctatg agggtgagga gttgaagcca
1261 tacacagagc ccgaggagga cttcggggac accaagagaa ttgaggtgat ggtgggtatg
1321 ggctacacac gggaagaaat caaagagtcc ttgaccagcc agaagtacaa cgaagtgacc
1381 gccacctacc tcctgctggg caggaagact gaggagggtg gggaccgggg cgccccaggg
1441 ctggccctgg cacgggtgcg ggcgcccagc gacaccacca acggaacaag ttccagcaaa
1501 ggcaccagcc acagcaaagg gcagcggagt tcctcttcca cctaccaccg ccagcgcagg
1561 catagcgatt tctgtggccc atcccctgca cccctgcacc ccaaacgcag cccgacgagc
1621 acgggggagg cggagctgaa ggaggagcgg ctgccaggcc ggaaggcgag ctgcagcacc
1681 gcggggagtg ggagtcgagg gctgcccccc tccagcccca tggtcagcag cgcccacaac
1741 cccaacaagg cagagatccc agagcggcgg aaggacagca cgagcacccc caacaacctc
1801 cctcctagca tgatgacccg cagaaacacc tacgtttgca cagaacgccc gggggctgag
1861 cgcccgtcac tgttgccaaa tgggaaagaa aacagctcag gcaccccacg ggtgccccct
1921 gcctccccct ccagtcacag cctggcaccc ccatcagggg agcggagccg cctggcacgc
1981 ggttccacca tccgcagcac cttccatggt ggccaggtcc gggaccggcg ggcagggggt
2041 gggggtggtg ggggtgtgca gaatgggccc cctgcctctc ccacactggc ccatgaggct
2101 gcacccctgc ccgccgggcg gccccgcccc accaccaacc tcttcaccaa gctgacctcc
2161 aaactgaccc gaagggttac cctcgatccc tctaaacggc agaactctaa ccgctgtgtt
2221 tcgggcgcct ctctgcccca gggatccaag atcaggtcgc agacgaacct gagagaatcg
2281 ggggacctga ggtcacaagt tgccatctac cttgggatca aacggaaacc gccccccggc
2341 tgctccgatt cccctggagt gtgaagctga ccagctcgcg ccctcctgag gccctgatgg
2401 cagctctgcg ccaggccaca gcagccgccc gctgccgctg ccgccagcca cagccgttcc
2461 tgctggcctg cctgcacggg ggtgcgggcg ggcccgagcc cctgtcccac ttcgaagtgg
2521 aggtctgcca gctgccccgg ccaggcttgc ggggagttct cttccgccgt gtggcgggca
2581 ccgccctggc cttccgcacc ctcgtcaccc gcatctccaa cgacctcgag ctctgagcca
2641 ccacggtccc agggccctta ctcttcctct cccttgtcgc cttcacttct acaggagggg
2701 aaggggccag ggaggggatt ctccctttat catcacctca gtttccctga attatatttg
2761 ggggcaaaga ttgtcccctc tgctgttctc tggggccgct cagcacagaa gaaggatgag
2821 ggggctcagc ggggggagct ggcaccttcc tggagcctcc agccagtcct gtcctccctc
2881 gccctaccaa gagggcacct gaggagactt tggggacagg gcaggggcag ggagggaaac
2941 tgaggaaatc ttccattcct cccaacagct caaaattagg ccttgggcag gggcagggag
3001 agctgctgag cctaaagact ggagaatctg ggggactggg agtgggggtc agagaggcag
3061 attccttccc ctcccgtccc ctcacgctca aacccccact tcctgcccca ggctggcgcg
3121 gggcactttg tacaaatcct tgtaaatacc ccacaccctc ccctctgcaa aggtctcttg
3181 aggagctgcc gctgtcacct acggttttta agttattaca ccccgaccct cctcctgtca
3241 gccccctcac ctgcagcctg ttgcccaata aatttaagag agtccccccc tccccaatgc
3301 tgaccctagg attttccttc cctgccctca cctgcaaatg agttaaagaa gaggcgtggg
3361 aatccaggca gtggtttttc ctttcggagc ctcggttttc tcatctgcag aatgggagcg
3421 gtgggggtgg gaaggtaagg atggtcgtgg aagaaggcag gatggaactc ggcctcatcc
3481 ccgaggcccc agttcctata tcgggccccc cattcatcca ctcacactcc cagccaccat
3541 gttacactgg actctaagcc acttcttact ccagtagtaa atttattgca ataaacaatc
3601 attganccc
//