LOCUS AB040463 1709 bp mRNA linear HUM 10-OCT-2001
DEFINITION Homo sapiens RTN-x mRNA for RTN-xS, complete cds.
ACCESSION AB040463
VERSION AB040463.1
KEYWORDS reticulon.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1709)
AUTHORS Eguchi,Y., Tagami,S. and Tsujimoto,Y.
TITLE Direct Submission
JOURNAL Submitted (22-MAR-2000) to the DDBJ/EMBL/GenBank databases.
Contact:Yutaka Eguchi
Osaka University Graduate School of Medicine, Biomedical Research
Center, Department of Medical Genetics; Yamadaoka 2-2, Suita,
Osaka 567-0871, Japan
REFERENCE 2
AUTHORS Tagami,S., Eguchi,Y., Kinoshita,M., Takeda,M. and Tsujimoto,Y.
TITLE A novel protein, RTN-xS, interacts with both Bcl-xL and Bcl-2 on
endoplasmic reticulum and reduces their anti-apoptotic activity
JOURNAL Oncogene 19, 5736-5746 (2000)
COMMENT
FEATURES Location/Qualifiers
source 1..1709
/db_xref="H-InvDB:HIT000059282"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_lib="human fetal brain"
/tissue_type="brain"
CDS 245..1366
/codon_start=1
/gene="RTN-x"
/note="reticulon family"
/product="RTN-xS"
/protein_id="BAB18928.1"
/transl_table=1
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIV
SVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSA
LGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPV
IYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE"
BASE COUNT 355 a 491 c 471 g 392 t
ORIGIN
1 gctggcctca ctcctagctc atctgggcgg cggcggcaag tggggacagg gcgggtggcg
61 catcaccggc gcggaggcag gaggagcagt ctcattgttc cgggagccgt caccacagta
121 ggtccctcgg ctcagtcggc ccagcccctc tcagtcctcc ccaaccccca caaccgcccg
181 cggctctgag acgcggcccc ggcggcggcg gcagcagctg cagcatcatc tccaccctcc
241 agccatggaa gacctggacc agtctcctct ggtctcgtcc tcggacagcc caccccggcc
301 gcagcccgcg ttcaagtacc agttcgtgag ggagcccgag gacgaggagg aagaagagga
361 ggaggaagag gaggacgagg acgaagacct ggaggagctg gaggtgctgg agaggaagcc
421 cgccgccggg ctgtccgcgg ccccagtgcc caccgcccct gccgccggcg cgcccctgat
481 ggacttcgga aatgacttcg tgccgccggc gccccgggga cccctgccgg ccgctccccc
541 cgtcgccccg gagcggcagc cgtcttggga cccgagcccg gtgtcgtcga ccgtgcccgc
601 gccatccccg ctgtctgctg ccgcagtctc gccctccaag ctccctgagg acgacgagcc
661 tccggcccgg cctccccctc ctcccccggc cagcgtgagc ccccaggcag agcccgtgtg
721 gaccccgcca gccccggctc ccgccgcgcc cccctccacc ccggccgcgc ccaagcgcag
781 gggctcctcg ggctcagtgg ttgttgacct cctgtactgg agagacatta agaagactgg
841 agtggtgttt ggtgccagcc tattcctgct gctttcattg acagtattca gcattgtgag
901 cgtaacagcc tacattgcct tggccctgct ctctgtgacc atcagcttta ggatatacaa
961 gggtgtgatc caagctatcc agaaatcaga tgaaggccac ccattcaggg catatctgga
1021 atctgaagtt gctatatctg aggagttggt tcagaagtac agtaattctg ctcttggtca
1081 tgtgaactgc acgataaagg aactcaggcg cctcttctta gttgatgatt tagttgattc
1141 tctgaagttt gcagtgttga tgtgggtatt tacctatgtt ggtgccttgt ttaatggtct
1201 gacactactg attttggctc tcatttcact cttcagtgtt cctgttattt atgaacggca
1261 tcaggcacag atagatcatt atctaggact tgcaaataag aatgttaaag atgctatggc
1321 taaaatccaa gcaaaaatcc ctggattgaa gcgcaaagct gaatgaaaac gcccaaaata
1381 attagtagga gttcatcttt aaaggggata ttcatttgat tatacggggg agggtcaggg
1441 aagaacgaac cttgacgttg cagtgcagtt tcacagatcg ttgttagatc tttattttta
1501 gccatgcact gttgtgagga aaaattacct gtcttgactg ccatgtgttc atcatcttaa
1561 gtattgtaag ctgctatgta tggatttaaa ccgtaatcat atctttttcc tatctaatct
1621 atctgaggca ctggtggaat aaaaaacctg tatattttac tttgttgcag atagtcttgc
1681 cgcatcttgg caagttgcag agatggtgg
//