LOCUS AB038951 6470 bp mRNA linear HUM 23-FEB-2001
DEFINITION Homo sapiens ALS2CR3 mRNA for amyotrophic lateral sclerosis 2,
candidate 3, complete cds.
ACCESSION AB038951
VERSION AB038951.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6470)
AUTHORS Hadano,S., Ikeda,J. and Hayden,M.R.
TITLE Direct Submission
JOURNAL Submitted (24-FEB-2000) to the DDBJ/EMBL/GenBank databases.
Contact:Shinji Hadano
Tokai University, The Institute of Medical Sciences; Bohseidai,
Isehara, Kanagawa 259-1193, Japan
REFERENCE 2
AUTHORS Hadano,S., Yanagisawa,Y., Skaug,J., Fichter,K., Nasir,J.,
Martindale,D., Koop,B.F., Scherer,S.W., Nicholson,D.W.,
Rouleau,G.A., Ikeda,J.-E. and Hayden,M.R.
TITLE Cloning and characterization of three novel genes, ALS2CR1,
ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral
sclerosis (ALS2) critical region at chromosome 2q33-q34: Candidate
genes for ALS2.
JOURNAL Genomics 71, 200-213 (2001)
COMMENT
FEATURES Location/Qualifiers
source 1..6470
/chromosome="2"
/db_xref="H-InvDB:HIT000059247"
/db_xref="taxon:9606"
/map="2q33"
/mol_type="mRNA"
/note="UniGene ID: Hs.154248"
/note="clone: 5'RACE clone: 1-1139 nt"
/note="clone: IMAGE:28264: 2142-3854 nt"
/note="clone: IMAGE:40750: 3890-6470 nt"
/note="clone: IMAGE:531437: 838-3720 nt"
/note="clone: RT-PCR product: 3737-4030 nt"
/note="composite sequence: 1-6470 nt"
/organism="Homo sapiens"
CDS 382..3126
/codon_start=1
/gene="ALS2CR3"
/note="candidate 3"
/product="amyotrophic lateral sclerosis 2"
/protein_id="BAB32501.1"
/transl_table=1
/translation="MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELV
SLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRV
EQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHILSEQNESLEEQLGQAFDQ
VNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLK
ELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDE
LIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNM
ECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEES
SLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTE
DKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQ
RKIQVLADQKEGVSGCVTPTESLASLCTTQSEITDLSSASCLRGFMPEKLQIVKPLEG
SQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLPGDAIYHISDLEEDEEEGITFQVQQ
PLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANPGKCLSCTNSTFTFTTCRILHPS
DITQVTPSSGFPSLSCGSSGSSSSNTAVNSPALSYRLSIGESITNRRDSTTTFSSTMS
LAKLLQERGISAKVYHSPISENPLQPLPKSLAIPSTPPNSPSHSPCPSPLPFEPRVHL
SENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKRLGIARVVKNPGAQENG
RCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAPVCTSSPKMGVLKED
"
regulatory 3801..3806
/regulatory_class="polyA_signal_sequence"
regulatory 6435..6440
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1923 a 1309 c 1392 g 1846 t
ORIGIN
1 cgcagaaccg aggtcgccga gtgatgatgt tgtgaagtcg cccgcctgtc cctgccacgc
61 ccgggcggtt gctggcagtg ggagcagcgg cagcagcttc ggctgctgct ttcaggctgc
121 cgctgcatta ggggcttcct gaggaaacgc gggcggacga cagaggatgc cgaaccactc
181 cagtcatgac tgtccaaagt atgataatca catgagagtg ctcgttgcta cggatgtcat
241 ttgactcatc agagaaaatc tgtctaaaag aaaatatcca tgtgaccaaa tccatttcat
301 tattgaatgg cttgatggat ttcctttact ctgattcata ccaaagctgt ccttctcaac
361 caaagcaaga aaggatcctg catgagtcaa tcccagaatg caatttttac atcaccaaca
421 ggtgaagaaa acctcatgaa tagcaatcac agagactcgg agagcatcac tgatgtctgc
481 tccaatgagg atctccctga agttgagctg gtgagtctgc tagaagaaca actaccacag
541 tataggctaa aagtagacac tctctttcta tatgaaaatc aagactggac tcagtctcca
601 caccagcggc agcatgcatc tgatgctctc tctccagtcc ttgctgaaga gactttccgt
661 tacatgattc taggcacaga cagggtggag cagatgacca aaacttacaa tgacatcgac
721 atggttacac atctcctggc agagagggat cgtgatctgg aactcgctgc tcgaattgga
781 caagctctct taaagcggaa ccatatctta tctgagcaga acgaatccct ggaggagcaa
841 ttgggacaag cctttgatca agttaatcag ctgcagcatg agctatgcaa gaaagatgag
901 ttacttcgaa tcgtctccat tgcttctgaa gaaagtgaaa ctgattccag ctgttctaca
961 cctcttcggt tcaatgagtc ctttagctta tctcaagggt tgctgcagtt ggaaatgctg
1021 caagaaaagc tcaaggaact ggaagaagag aatatggctc ttcgatccaa ggcttgtcac
1081 ataaagacag aaactgttac ctatgaagaa aaggaacaac agcttgtcag cgactgtgtt
1141 aaagaacttc gtgaaacaaa tgctcagatg tccagaatga ctgaagaatt gtcagggaag
1201 agtgatgagc tgattcgata ccaagaagag ctttcctctc ttttgtcaca gattgtagac
1261 cttcagcata aacttaaaga acatgtgatt gagaaggaag aactaaaact tcacctgcaa
1321 gcttccaaag atgcccaacg gcaactgaca atggagctgc acgagttaca agacaggaat
1381 atggagtgtc taggaatgtt acatgaatcc caagaagaaa taaaggaact tcgtagtaga
1441 tctggcccta ctgctcatct ctacttctcc caatcatatg gagcttttac tggggaatct
1501 ttggcagctg agattgaggg gactatgcgt aaaaagctga gtttggatga ggaatcttct
1561 ctctttaaac aaaaagccca acagaagcgg gtatttgata ccgtcaggat tgccaatgac
1621 acacggggcc gctctatctc attcccagct ctgttaccca ttccaggctc caaccgttca
1681 agtgtcatca tgacagcaaa accttttgag tctggtcttc agcaaacaga ggacaaatca
1741 ctcctgaacc aggggagcag ctcagaggag gttgcaggga gctcccagaa gatgggccaa
1801 ccaggaccct caggagatag tgatttggct acagcactgc atcgccttag cttgcgtcga
1861 caaaactatt taagtgagaa gcagttcttt gctgaagaat ggcagcggaa gatccaggtt
1921 ctggcagacc agaaggaagg agttagtggc tgtgtcaccc cgacagagag ccttgcctct
1981 ctctgcacca cccagtcaga gatcacagac ctcagcagtg ccagttgcct tcgaggtttt
2041 atgccagaaa aattacaaat tgtcaagccc cttgaaggat cacaaactct gtatcactgg
2101 cagcagcttg ctcaaccaaa cttgggaacc atccttgatc cacgaccagg tgtcattact
2161 aaaggcttta cccagttgcc cggggatgct atttatcaca tctcagattt agaagaggat
2221 gaagaggagg gtattacttt tcaggttcag caacctcttg aagtggaaga gaaactttca
2281 acatccaagc cagtaacagg gatcttcctg ccacccatta cttcagcagg tggaccagtt
2341 acagttgcaa ccgccaaccc aggaaagtgc ctgtcgtgca caaactcaac attcactttc
2401 accacctgta gaatattaca tccctctgac atcactcagg ttacccccag ctctgggttc
2461 ccttcattat cctgtggaag tagcggtagc agttcatcca acacggctgt gaattctcct
2521 gccttgtcct atagactcag cattggtgag tccatcacca accgacgaga ttccactaca
2581 accttcagta gcaccatgag cttggccaaa cttctacaag agcgaggcat ctctgccaaa
2641 gtgtaccaca gcccaatttc agagaacccc ctccagcctc tccctaaatc cctggctatc
2701 ccttccacac caccaaattc accatctcac tcaccttgcc cttctccttt accctttgag
2761 cctcgagtgc atctctctga aaattttttg gcctctcgac cagctgagac attcctccag
2821 gagatgtatg gcttgagacc ctcccggaac cctcctgatg ttggccagtt gaagatgaac
2881 ttagtggaca ggctgaagag actggggata gccagagtgg tcaagaaccc tggtgcccaa
2941 gagaatggaa gatgccagga ggcagaaatt ggtcctcaaa aaccagattc tgctgtttat
3001 ttaaattcag gtagcagttt attaggtgga ctaaggagga atcagagtct tccagtcata
3061 atgggtagct ttgctgcccc agtttgcaca tcctcaccca aaatgggtgt cctgaaggag
3121 gactgaggtt cagcagttaa ctgacctttt atacaagtta gcacatgaag gatagatatg
3181 cactgaaaca tgtggtctgg tctgacttga gagaaaagga atgttgcaca agggttgtga
3241 atgtgaaagg gggaatggag gaatggaaat aaaattggga tgagccctaa tggaggaagt
3301 cgggcaaatt gaaagtataa atgaatgggc catgagtgtt cagagggaga aaagaaaggt
3361 ttaatatact ccttcagttg agttttcttg tcttgaacat aaaaagtgaa tacaaataaa
3421 ttcagtaata ctaaaacata cagagatact gaacttgctg gcacatttac ttctggtaag
3481 cataaagcag agagaaccca ggttagaagg atgggaagag aaaaggagca gttttattgc
3541 ttatagaaag ccgttctgag gggttggtgg ggtaagctca gtctattact gagacaatag
3601 tgagatggct tatatgtttc ccctgttaat atctggttaa attatgtatc catcaaatgg
3661 tatgctcgca gcattagcaa aattaggagt ttcatctttt tcattgaatc acaggtggag
3721 actcctattt tcctttctgt tttcaggcct ttgagcccct gggagcccaa ataccactca
3781 attattttgt atttatgatt aataaaagtt cattttttaa atttgtattt ttatacaacc
3841 tccaaaaaaa aaaacaactg ggtagagggt gggagggatt tacttttaag aggcaaaatg
3901 tgagtaaatt gaaaccaaga aaacttgttt ttagaatatt tcgtctgaat aagtacagta
3961 gccaaggaat acaaacctaa ttgcatgttt ttaaaaattc cttggaggct ggaaggggtt
4021 aagccagaag tgcaatcaat aggaattagg gaatgttgta tatttatata tgtaaacttt
4081 ttttgtaaga aaagttggtg acaactaaac caactttttc caaagtgcgc tatgcatatt
4141 tttaatgaaa gatgacatgt atttgcacaa aaattctcag gcacattaaa ttattgtaaa
4201 ctgaagtaaa acccgggtgc ttgctttgag attgtggttt tttcttccta atgtaaaata
4261 aaataaaaca catctgcctt cttgatattt atagaattag agaataaact ttttaatggg
4321 ggagtcaaag ctttttcttt ttctctaagg ttcttttttt tattcaaact gtatgaaatg
4381 gcaaagtgag gctctggggt tagatttcag cattcagcag ttgacacagg ctaagaaatg
4441 gaaagaagta gatctgtttt ttctcaatgt tgctgagcaa agtctgcttc tcatcagatg
4501 acgtggcttt gtctagacag cacgcagttc agaaagaaat gtctttatac aaaagacatg
4561 atagagaaaa gatgagagag gggactaatt attttgttta tgaaaatggc aagtaaatta
4621 cttgatcttt ttggtgctta atttgcaaat gttttgttcc tttgtcctga cttaaaggca
4681 gttttctgaa gaactcttga ctcttgctcc tatggttccc ataggcacac ctattcccag
4741 gccaaggaga gtccttcctc tccccttttg aggcatcccc gccatccccc cacttagagc
4801 tatgtgctca aaaagccaac atgaatgcag tggtaaaaat ttgttagttt cttatacttt
4861 ttagaatctc tcaataaaat ttttctaaat aaattccaca aaaacaaagg gtgaagatgg
4921 tctctccctt tcgttcccct tcactcagtt gtgctgaggt caatagagtg tagagtttca
4981 gaaaggattc cagcaggttt atatgtgaat ataagtgtcc ctgaatgggg caggcattaa
5041 atagaagaat ccctgctgtt taaatttccc gcatattcca attcactttt aaaaaatacc
5101 atttgaattt gtatttcata aagtgactct ggggtgctta ctttagtcaa ttcttaaaat
5161 tttttatttg ttccctaaga aagtaattac tgtttctgtt gcctggacag ttacagtttc
5221 caggaaacat caggaagtag gaaactgtag ggccagagag tagtacaacg ttaaattgtc
5281 cgatttatgt gtattactta aagctataaa ttgaactaga tcttgccgtg ctctgtattg
5341 agtataattt gtatactttt ttataattaa tgactaaatg atcactttgg aggcagggtg
5401 gtgggggtgt attagcagcc aaataagcat atctgatcaa aaagaaccag gcttagattt
5461 tttttaagta cattgatgtt gatgttccac cagaaacacc ttaagtgtat actgttgtgt
5521 aatgtctcta gaaaggaatc ctgtcttaaa actgggtttt gctgtttttt gaagtttcta
5581 cctaaaatca tttttggtat atcctgataa tctctataat actagaattg tctgcaaaat
5641 atagtaagaa gaattggagc ctaatagctg attcctccca atttatctgt tatgttttgt
5701 cactattcac attttagtct tttctacgat aaaaattgta tgtgtacttt catgccagta
5761 taggaaacct caatcttttt tttttttcgc ctttaagaag gttttcagtg attatacctc
5821 aggtatttct gagtgtccta ttgtctaata ggagaaatat cttcccgagc tcagaattaa
5881 aagttctcct aaattatgaa gatcccaaat cttatgtaaa taaccttagg catgagtcct
5941 tagggagaag ttaatgacca ttgttaaagt gcttttttag aaaatgttgt gctgtatgtt
6001 cttgatttga cataaatgaa tagactttgg caagggagga aataagttaa aaggcagctt
6061 acaagagcct attccctata aagggtataa ttttacacag tactcaaagc ttgttatctt
6121 ttctgaccat tttagtacag aattagtact tggtggttac taacatcaac ttgtgacatc
6181 tagaactagg gctcttagtg tttagtgggc cacttctctg atgtcagatg catgcagacc
6241 tgtactccac atgcaaccca acagcagtgc agtgtgataa ctgagcggtc gcatggcaga
6301 ggacatcccc ctcagagtgg gcacaagtgc cctctagggc agccagggga atactattgt
6361 tcgatacctg ggatttgact ttgtcaaaca gctctttgtg cccctatctt tgttttgtca
6421 aatgtagatc agttaataaa catgagtagc ttgaattttc aaaaaaaaaa
//