LOCUS AB036532 6213 bp DNA linear HUM 22-OCT-2004
DEFINITION Homo sapiens p53R2 gene for ribonucleotide reductase, complete cds.
ACCESSION AB036532 AB036524-AB036531
VERSION AB036532.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6213)
AUTHORS Tanaka,H., Arakawa,H. and Nakamura,Y.
TITLE Direct Submission
JOURNAL Submitted (05-JAN-2000) to the DDBJ/EMBL/GenBank databases.
Contact:Yusuke Nakamura
University of Tokyo, Institute of Medical Science, Human Genome
Center, Laboratory of Molecular Medicine; 4-6-1 Shirokanedai,
Minato-ku, Tokyo 108-8639, Japan
REFERENCE 2
AUTHORS Tanaka,H., Arakawa,H., Yamaguchi,T., Shiraishi,K., Fukuda,S.,
Matsui,K., Takei,Y. and Nakamura,Y.
TITLE A ribonucleotide reductase gene involved in a p53-dependent
cell-cycle checkpoint for DNA damage
JOURNAL Nature 404, 42-49 (2000)
COMMENT
FEATURES Location/Qualifiers
source 1..6213
/chromosome="8"
/db_xref="taxon:9606"
/mol_type="genomic DNA"
/organism="Homo sapiens"
exon 1..292
/gene="p53R2"
/number=1
/product="ribonucleotide reductase"
CDS join(245..292,453..608,769..885,1046..1179,1340..1434,
1595..1728,1889..1993,2154..2267,2428..2580)
/codon_start=1
/gene="p53R2"
/product="ribonucleotide reductase"
/protein_id="BAA92493.1"
/transl_table=1
/translation="MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVI
FPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGI
VNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIE
TMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLT
FSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIG
MNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRF
AVMAETTDNVFTLDADF"
intron 293..>322
/gene="p53R2"
/number=1
gap 323..422
/estimated_length=unknown
intron <423..452
/gene="p53R2"
/number=1
exon 453..608
/gene="p53R2"
/number=2
/product="ribonucleotide reductase"
intron 609..>638
/gene="p53R2"
/number=2
gap 639..738
/estimated_length=unknown
intron <739..768
/gene="p53R2"
/number=2
exon 769..885
/gene="p53R2"
/number=3
/product="ribonucleotide reductase"
intron 886..>915
/gene="p53R2"
/number=3
gap 916..1015
/estimated_length=unknown
intron <1016..1045
/gene="p53R2"
/number=3
exon 1046..1179
/gene="p53R2"
/number=4
/product="ribonucleotide reductase"
intron 1180..>1209
/gene="p53R2"
/number=4
gap 1210..1309
/estimated_length=unknown
intron <1310..1339
/gene="p53R2"
/number=4
exon 1340..1434
/gene="p53R2"
/number=5
/product="ribonucleotide reductase"
intron 1435..>1464
/gene="p53R2"
/number=5
gap 1465..1564
/estimated_length=unknown
intron <1565..1594
/gene="p53R2"
/number=5
exon 1595..1728
/gene="p53R2"
/number=6
/product="ribonucleotide reductase"
intron 1729..>1758
/gene="p53R2"
/number=6
gap 1759..1858
/estimated_length=unknown
intron <1859..1888
/gene="p53R2"
/number=6
exon 1889..1993
/gene="p53R2"
/number=7
/product="ribonucleotide reductase"
intron 1994..>2023
/gene="p53R2"
/number=7
gap 2024..2123
/estimated_length=unknown
intron <2124..2153
/gene="p53R2"
/number=7
exon 2154..2267
/gene="p53R2"
/number=8
/product="ribonucleotide reductase"
intron 2268..>2297
/gene="p53R2"
/number=8
gap 2298..2397
/estimated_length=unknown
intron <2398..2427
/gene="p53R2"
/number=8
exon 2428..6213
/gene="p53R2"
/number=9
/product="ribonucleotide reductase"
BASE COUNT 1624 a 872 c 1077 g 1840 t
ORIGIN
1 ggctggccga agttaggcgg agccccgagg cgggggaggc ggggccgggc cggcgcaggg
61 agagtcactc aatggacagg cgagaaagca ggaccggcgc ggcggggcgg ggccggccga
121 gtccctagag ctgggggcgg ggcggaccca gcggaccagc ggaccacctg ggtgctgtcg
181 tagttggagg tggcctgagg agctcagttc cctcagcgcc cgtagcttcg gcggagtctg
241 cgcgatgggc gacccggaaa ggccggaagc ggccgggctg gatcaggatg aggtaaatgt
301 tgctgttgcg tcttccccct cannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
421 nnaaaggcgt gtttgtactt tatttttcaa agagatcatc ttcagacacc aacgaaagtg
481 aaataaagtc aaatgaagag ccactcctaa gaaagagttc tcgccggttt gtcatctttc
541 caatccagta ccctgatatt tggaaaatgt ataaacaggc acaggcttcc ttctggacag
601 cagaagaggt acgtggcatt gcctccaaga gcattcacnn nnnnnnnnnn nnnnnnnnnn
661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
721 nnnnnnnnnn nnnnnnnntt aaaatttttg aaaatctttt tattccaggt cgacttatca
781 aaggatctcc ctcactggaa caagcttaaa gcagatgaga agtacttcat ctctcacatc
841 ttagcctttt ttgcagccag tgatggaatt gtaaatgaaa atttggtaag atttttgctt
901 gatttaactt ttgttnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnntggat
1021 atatctattt tccttatctt cttaggtgga gcgctttagt caggaggtgc aggttccaga
1081 ggctcgctgt ttctatggct ttcaaattct catcgagaat gttcactcag agatgtacag
1141 tttgctgata gacacttaca tcagagatcc caagaaaagg tattgttggg attttattta
1201 caaaatattn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna ctttgctgtt
1321 cattcttttg tttttacagg gaatttttat ttaatgcaat tgaaaccatg ccctatgtta
1381 agaaaaaagc agattgggcc ttgcgatgga tagcagatag aaaatctact tttggtatgt
1441 ggctctaatt tatgtatgat cagannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1561 nnnncaaaaa ttgaaacgat tttatgtctc ccaggggaaa gagtggtggc ctttgctgct
1621 gtagaaggag ttttcttctc aggatctttt gctgctatat tctggctaaa gaagagaggt
1681 cttatgccag gactcacttt ttccaatgaa ctcatcagca gagatgaagt aaggaatgga
1741 atgtttttct agttatatnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntt
1861 tgacaatgac atttttcttc ccttttaggg acttcactgt gactttgctt gcctgatgtt
1921 ccaatactta gtaaataagc cttcagaaga aagggtcagg gagatcattg ttgatgctgt
1981 caaaattgag caggtaaacc gggaagtttg tgtaattagc acannnnnnn nnnnnnnnnn
2041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2101 nnnnnnnnnn nnnnnnnnnn nnntacttta ttctgttttt gttttcatcc caggagtttt
2161 taacagaagc cttgccagtt ggcctcattg gaatgaattg cattttgatg aaacagtaca
2221 ttgagtttgt agctgacaga ttacttgtgg aacttggatt ctcaaaggta atgtgtttaa
2281 aaatgtgtta ctactagnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnaat
2401 gtctaataat atttctttcc tttttaggtt tttcaggcag aaaatccttt tgattttatg
2461 gaaaacattt ctttagaagg aaaaacaaat ttctttgaga aacgagtttc agagtatcag
2521 cgttttgcag ttatggcaga aaccacagat aacgtcttca ccttggatgc agatttttaa
2581 aaaacctctc gttttaaaac tctataaact tgtcattggt aaatagtagt ctattttcct
2641 ctgcttaaaa aaaattttaa gtatatcctt taaaggactg ggggtttgct caaaaggaaa
2701 tccaaaacct attctaaaca atttgcattt atataatttt cctgtttaac aacaagagtg
2761 tgacctaaat gcttttgtct tgtcactgaa ataaaagatg gcattatgtg gttaagagca
2821 tggggcgagg ggtcagacat gagtctaagg ttctgccctt actccagtgt gtgacccttg
2881 gcaagtcagt taatcttggt aaacctcggt gtacttatct ttaaaatggg agtaatagta
2941 ggtcctaaat tcatagagtg gatattagga ttaggatgca aaaataaatg cttaaccaac
3001 actactactg ttagcaccac tactaattat cattcattga taatattaat tgcaatgatg
3061 ttgtaataaa atactctcat ttccttaaaa taattgtgat tctaggtcct aggatctaga
3121 attagatctt tgtattttta atgcttaggg gaagaatata agtatctcct taaaaagaac
3181 ataattctca ttcacgcaag aataagttct ttgaattcct tagtatgtag tgaagaaaat
3241 ttagttgtta gttgctttgg gaagcctact tatggagtgg aaaccaggag gttatcatgg
3301 tagttgacct tgtaagaaaa atgattcttc ttcagaaatt aaaaacataa ctattgccag
3361 atttagctct ggaatgttta gaatcaggct agaatagcat tttccaaaga atattctaag
3421 agctattagc tcctctagat attttgttgg gggaaaaagg ggattctgtg gtcagatgag
3481 tttgggaaat gctgaacact tcattcttct ttagcaagta cagtcagtac atcaaagact
3541 gagcagttca gtggtacata aatttatctc gccctgcata ttcccaacat acttaacaca
3601 gatgtttttt acctgttaac atctcaccca gctagtgttc ctcagaacaa agattggaaa
3661 aagctggccg agaaccattt atacatagag gaagggctta cggactgaga aagggagaac
3721 atggtaggga ttattgaatc atttcaaatt tataccaagc ctgaatagtg taccagcaat
3781 tgacttaggc tgtgtttctt tatggtttta aaactcttga gctgttataa gagatagttc
3841 ttttaatgtg actatgcaac atgatagcca atggtgaggg aaaaggaggt ttctctagaa
3901 gagtctgatg aaaggccggg aaccaaggtt tttgagaagt ctgcccctat ttatttttag
3961 taagtatcaa gaggtagcct gagcctagtt agagttagac ctgtctttgg atgaagaagt
4021 cttaatactg aaatactgaa tttttaatac attattattt ggtattctgt ataccccttc
4081 aagcagttgt ttcccattcc caacaaactg tactttatac aattctggat gctaaaactt
4141 agagattttc tctttgcata aattttggct ccattctttc cataacaatc taatcaaaac
4201 tgggagttct caagtgaatg caaaaggagc aggccataac tttatttgtt agagacactg
4261 tcagaaactt gagatctttt ggcctatgat aataccatta atttttgcat tgcttcagtt
4321 tgccaagtgt ttttacatca tctcatttga tctcaaaaca gcttgacaga gcaactgtta
4381 ttgaaatatt acagatggaa agaatgaggc tcagggaagt taaatgactt ggccaagatc
4441 tgctcatcgt cactgtctgt acagtatttt tttttagagg ttgtaatgtc tcagatttag
4501 tcctttacca tctatgttga tttgcttttg tctatttcct cattaattga atatacttta
4561 aatatatata ttaaagtatc aaaatataga gagacatttg aactgtattc aggtaatatg
4621 tttaaagata tttatatatt gccatacaaa aacttaacat ttaaaactga taatatctgt
4681 aatgacatca gaatgaaaga aaaaaaattg tacagtgtat attcctttgt tttgaatcca
4741 aatctttttc ataggtaatg acagatgcct taatgtgaag cttatttata atagcaataa
4801 acctaactgg atttggatga agaagtctta atactgacat actggatttt taatgcactg
4861 gtttgttatt tggtattcta tctctttttc caggcctcca ggttgcacat ttatttatta
4921 tgttcaatac tttggttctt agttcttaaa gaatcaagaa gttgtgtaat cttttaaaaa
4981 tattatcttg cagataaaga aaaaaattaa gagtgtgttt acaactgttt tctctttttt
5041 acagtacatg tatttaaatc attgctataa taaagttaag ttcattagga atataaaaac
5101 ttgcagttct atgatagatt gcatttatta aaaatgtttc attgtatcac atagaaatat
5161 ggccaggaag gacttgagaa gacagtttga tccattgctt ttagacagga ctgggttttg
5221 ctgtccaatt atatacaata atagtttttc ttacaactaa gctggcccca gccttgtctt
5281 gatattaata catgaaattt ttataattgt ctcattgtct catttagaaa catccatatt
5341 tttctgcttt ttctattgcc attttttatt tgtgcatgaa ttgattattg agaaaatgta
5401 gcagtttgca tatttaaaaa ttaatcattt tgcattttac atttaaatat gctaacatcg
5461 ctgtcataga attcccaaat ttcatttgta gatactgaac taagggctaa tgtcaggagc
5521 tgatttttaa tgataaagct gcagatgggc taaataaaag ccaaattaat cctacaatca
5581 ggtattatgt ttttaaacca agttgagtga attggtagtg gacttgggaa atcttcccca
5641 gcagaatctg gatgaatggc acagaattga aatctctttg tttcccacca tttcccttta
5701 agtgctctgc tcctttgtaa aaagttaaag atttgaaaga gaatctcata ttcccgaggc
5761 attaggaaga aaggatttaa tcccttcaat ttggggctta atcttgttta aaaaaatgta
5821 agtgaagatg gaaggctgga gagaatgatt gctttttgta cagttaaata aggtcacaat
5881 attcttacat actttgtttt acaactgtgt tttcattttt tcaaatgtct ggccatttag
5941 caaagttatt tactatttac tgtgtacata gaaaggttta ttatgtgtgg tgtatctaaa
6001 tttttttttg ctgaaataca ttatggtcaa tcaagccaag cctgcatgta cagaatttgt
6061 ttttttttca aataaattag ttgttttctt atttttttgg cttagtatgt tgaaataaac
6121 tatggtatct tcatcatttt gtacatttcc tttttgagga aggtttcttt ataagtgcaa
6181 gggctaccct aataaaggaa tgtatatact tac
//