LOCUS AB033598 3413 bp DNA linear HUM 23-OCT-2004
DEFINITION Homo sapiens gene for melatonin 1b receptor, complete cds.
ACCESSION AB033598 AB033597
VERSION AB033598.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3413)
AUTHORS Ebisawa,T.
TITLE Direct Submission
JOURNAL Submitted (14-OCT-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Takashi Ebisawa
Saitama Medical School, Dept of Psychiatry; 38 Morohongo,
Moroyama-cho, Iruma-gun, Saitama 350-0495, Japan
REFERENCE 2
AUTHORS Ebisawa,T., Uchiyama,M., Kajimura,N., Kamei,Y., Shibui,K., Kim,K.,
Kudo,Y., Iwase,T., Sugishita,M., Jodoi,T., Ikeda,M., Ozeki,Y.,
Watanabe,T., Sekimoto,M., Katoh,M., Yamada,N., Toyoshima,R.,
Okawa,M., Takahashi,K. and Yamauchi,T.
TITLE Genetic polymorphisms of human melatonin 1b receptor gene in
circadian rhythm sleep disorders and controls
JOURNAL Neurosci. Lett. 280, 29-32 (2000)
COMMENT sequence 1..1459
5'-intronic sequence and 3'-UTR sequence were determined using
vectorette libraries. Exon sequence was determined by
PCR-amplification of human hypothalamic cDNA.
sequence 1560..3413
5'-intronic sequence and 3'-UTR sequence were determined using
vectorette libraries. Exon sequence was determined by
PCR-amplification of human hypothalamic cDNA
FEATURES Location/Qualifiers
source 1..3413
/db_xref="H-InvDB:HIT000383137"
/db_xref="taxon:9606"
/mol_type="genomic DNA"
/organism="Homo sapiens"
CDS join(866..1088,1999..2864)
/codon_start=1
/product="melatonin 1b receptor"
/protein_id="BAA92315.1"
/transl_table=1
/translation="MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALS
AVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIF
YDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLH
ICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSF
CYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAI
NPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQ
DASKGSHAEGLQSPAPPIIGVQHQADAL"
exon <866..1088
/number=1
/product="melatonin 1b receptor"
gap 1460..1559
/estimated_length=unknown
exon 1999..>2864
/number=2
BASE COUNT 665 a 995 c 856 g 797 t
ORIGIN
1 gatcacgact caaacatttt taataaaggg cacctgagtt ccttctttat tgtaatcatg
61 cctcaatctt cttcttgtcc taacccctcc aaaaaccaca tcataacccc caatattggc
121 catacatcta tttaagtatt atgtgtaaat atatgttggt aaatatgtta aagtattggc
181 tttataaaga ggacccagta gagacatcat caatgccccc cacaataccc agcgagtgct
241 tggaaaatgg ctaggttcgt atttttctgc agctccctag aatataacag tctaccctac
301 tttgttctgg gctctgtccc cacatcttag gagttgcatt ctctttcggg ctgcacagcc
361 ctatgggacg tcaaaccttg cctttcttga caactgatgg gaggtcccta ccatcagcac
421 cttctccagt ctatcaacct gggttggacg tccctaccta gacacagctt ctcttgggga
481 cgctgtggag gaaatcgggg tctcgggtgt ggctatatac tcagggacag aagctagacg
541 cgctccgcag cctgaggtgg gccaggcatc tgctgggctc ggggtggcag agacagctgt
601 gcggtcccag ctgttcctga gcgcaccgct gagggacgca ctcccttcta caacggctgc
661 accccaagtc ctcctcccat tcctatattt ttctccatcc cctgcccacg cttaattagt
721 tatctcctcc agacccctcc ccactggcct cctcccttgc acacgcgagc tgggcaggga
781 agagagcgcc cggctcagta ctgcgcgcgc cctgcggctg tccggggccg cgcggtggcc
841 aaagcacagc gcgggagagt ctgcgatgtc agagaacggc tccttcgcca actgctgcga
901 ggcgggcggg tgggcagtgc gcccgggctg gtcgggggct ggcagcgcgc ggccctccag
961 gacccctcga cctccctggg tggctccagc gctgtccgcg gtgctcatcg tcaccaccgc
1021 cgtggacgtc gtgggcaacc tcctggtgat cctctccgtg ctcaggaacc gcaagctccg
1081 gaacgcaggt gagcaccatt cctgatgctg ggtgctggca tcgggccctt ccttgtcttc
1141 tgatcttgtc cctgaccccg ggatatgcgc tgccttttcc ctcctcagcc cgggctcccc
1201 tttcccttca ctctaaccta ttccttaagt ttgactctgc actcaaaagt tagggtgagt
1261 tttgcccctc cgaagtgcgg ctgcccagga cgcgcttggc acagagggaa ttgcggaaag
1321 ttttactggc gcgctttttg gccgggcgcc ggcgctgtgg gaacccacgc tgctggatgc
1381 catcgctacc ccgtcgcgct ccaatgcgtg tctttccaga ggtgcccaca tcaggccaca
1441 gaaatctcac cacctgtacn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna
1561 atgtgaggga gcgatgatag tgatgagaaa tccacactcc tgactttcag actctcctcc
1621 tccgaaatct ttgctggagc ttaaatggtg caaagcccgt gagcatctgt gcctatcatg
1681 gaaacagtta gcatgtgtca gcacctgtta aatccctgag cactttgtat cattaattct
1741 tacagctata ctatgaggta ggtatcactg cccctagttc acaaatgagg aaaatggggc
1801 tctgagagcc taaacagctt gcctcagtca tatagctagt gagtggcaga aatgcaatct
1861 gagtcttcag ttctgtgcct ctaagagcca cttggtttcc actcacattg ccaaaagtaa
1921 cttcgtggag ggtaggatgt tctacagaat ctaagtcgtg gggtctcgtg ctgactgttg
1981 ctctgtttgc tgcttcaggt aatttgttct tggtgagtct ggcattggct gacctggtgg
2041 tggccttcta cccctacccg ctaatcctcg tggccatctt ctatgacggc tgggccctgg
2101 gggaggagca ctgcaaggcc agcgcctttg tgatgggcct gagcgtcatc ggctctgtct
2161 tcaatatcac tgccatcgcc attaaccgct actgctacat ctgccacagc atggcctacc
2221 accgaatcta ccggcgctgg cacacccctc tgcacatctg cctcatctgg ctcctcaccg
2281 tggtggcctt gctgcccaac ttctttgtgg ggtccctgga gtacgaccca cgcatctatt
2341 cctgcacctt catccagacc gccagcaccc agtacacggc ggcagtggtg gtcatccact
2401 tcctcctccc tatcgctgtc gtgtccttct gctacctgcg catctgggtg ctggtgcttc
2461 aggcccgcag gaaagccaag ccagagagca ggctgtgcct gaagcccagc gacttgcgga
2521 gctttctaac catgtttgtg gtgtttgtga tctttgccat ctgctgggct ccacttaact
2581 gcatcggcct cgctgtggcc atcaaccccc aagaaatggc tccccagatc cctgaggggc
2641 tatttgtcac tagctactta ctggcttatt tcaacagctg cctgaatgcc attgtctatg
2701 ggctcttgaa ccaaaacttc cgcagggaat acaagaggat cctcttggcc ctttggaacc
2761 cacggcactg cattcaagat gcttccaagg gcagccacgc ggaggggctg cagagcccag
2821 ctccacccat cattggtgtg cagcaccagg cagatgctct ctagcctgga tctgaggcac
2881 accagcagca tgacaaactc atgaaatggt gggagagagt ctgctgcaag ggtgagacca
2941 ggcagcctgc tgggccacac tgtcctgttg gcatcacagc cccaaggctg ggggaacttc
3001 atgctgggac aagcagccca tcaacgccat gggttcaggc tgatccagga gatgctcaca
3061 ggccacagga cctggaaaac actcttggtg gtgtcttggg gatttggtgc acacaagacc
3121 aaggaaagga cagaatgagg aaaggcctgg ggcagaagag cccaactcct tctcatagct
3181 gaccctcatc ctcctgcctt ggcctcctgg ctgctttctc cccttccccc cagcatggca
3241 ggatctcttc ctgttagcaa ggatgaaaga gagaggtcag taggactgga acttggtaac
3301 tacaagggcc tcaggtgggg caggtgcaga gggctctccc ttctctcgtc cgttccttac
3361 cttcgacaga cagcgtcctc tccttgcgat cgggggcggg actctagcct cga
//