LOCUS AB033492 5634 bp mRNA linear HUM 21-NOV-2001
DEFINITION Homo sapiens hHDC mRNA for homolog of Drosophila headcase,
complete cds.
ACCESSION AB033492
VERSION AB033492.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5634)
AUTHORS Horii,A.
TITLE Direct Submission
JOURNAL Submitted (12-OCT-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Akira Horii
Tohoku University School of Medicine, Department of Molecular
Pathology; 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575,
Japan
REFERENCE 2
AUTHORS Makino,N., Yamato,T., Inoue,H., Furukawa,T., Abe,T., Yokoyama,T.,
Yatsuoka,T., Fukushige,S., Orikasa,S., Takahashi,T. and Horii,A.
TITLE Isolation and characterization of the human gene homologous to the
Drosophila headcase (hdc) gene in chromosome bands 6q23-q24, a
region of common deletion in human pancreatic cancer
JOURNAL DNA Seq. 11, 547-553 (2001)
COMMENT
FEATURES Location/Qualifiers
source 1..5634
/chromosome="6"
/db_xref="H-InvDB:HIT000059090"
/db_xref="taxon:9606"
/map="6q23-q24"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 286..1917
/codon_start=1
/gene="hHDC"
/product="homolog of Drosophila headcase"
/protein_id="BAA85322.1"
/transl_table=1
/translation="MPNPKNSKGGRKNKRANSSGDEQENGAGALAAAGAAGAAAGGAL
AAAAGCGAAAAGAPGAGGAAGAGGAGTGAANAAAAAGAAAAGDAKNEAPCATPLICSF
GRPVDLEKDDYQKVVCNNEHCPCSTWMHLQCFYEWESSILVQFNCIGRARSWNEKQCR
QNMWTKKGYDLAFRFCSCRCGQGHLKKDTDWYQVKRMQDEKKKKSGSEKNTGRPPGEA
AEEAKKCRPPNKPQKGPSHDLPRRHSMDRQNSQEKAVGAAAYGARSPGGSPGQSPPTG
YSILSPAHFSGPRSSRYLGEFLKNAIHLEPHKKAMAGGHVFRNAHFDYSPAGLAVHRG
GHFDTPVQFLRRLDLSELLTHIPRHKLNTFHVRMEDDAQVGQGEDLRKFILAALSASH
RNVVNCALCHRALPVFEQFPLVDGTLFLSPSRHDEIEYDVPCHLQGRLMHLYAVCVDC
LEGVHKIICIKCKSRWDGSWHQLGTMYTYDILAASPCCQARLNCKHCGKPVIDVRIGM
QYFSEYSNVQQCPHCGNLDYHFVKPFSSFKVLEAY"
repeat_region complement(3385..3685)
/note="Alu repeat"
regulatory 5594..5599
/regulatory_class="polyA_signal_sequence"
polyA_site 5611
/note="23 a nucleotides"
BASE COUNT 1487 a 1175 c 1364 g 1608 t
ORIGIN
1 gccttttccc tccggctcgg gagcgtctcg cttgcgcccc gggcccgcgg cgcccgcgcg
61 gctgcgagcc tcgggtggcc gcgtgccggc tccaggaagc cggagagggc gcggcggcca
121 ggatggcgcg gcacgggccg tgcggctaga cgggagccga gggaaccgcc ggctcgcgcc
181 ctccgttctt tcccggagcc ggcttcacgc agggccggga acggccgtgc ctctgggatc
241 cgccttcgct gacgccgggc acctacctgg acgcgagcga gcgagatgcc caaccccaaa
301 aacagcaaag gcggccgcaa aaacaagcgc gccaacagca gcggcgacga gcaggaaaat
361 ggagccgggg ccctggcagc ggcgggcgcg gcgggagcgg cggccggggg ggccctggcg
421 gcggcggccg gttgcggggc ggcggcggcg ggcgcgccgg gcgccggagg cgcggcgggc
481 gccggaggcg cggggactgg cgccgcgaac gctgcggccg ccgcgggggc tgcggccgcg
541 ggcgatgcca aaaacgaagc cccatgtgcc actcccctga tctgcagctt cggtaggccg
601 gtggacctgg agaaggacga ctaccagaag gtggtgtgca acaacgagca ctgcccctgc
661 agcacctgga tgcacctgca gtgcttctac gagtgggaga gcagcatcct cgtccagttc
721 aactgcatcg gccgcgcgcg cagctggaac gagaagcaat gccgccagaa catgtggaca
781 aagaagggct acgacctggc cttccgcttc tgctcttgcc gctgtggcca gggccacttg
841 aagaaggaca cagactggta tcaggtgaag cggatgcagg acgagaaaaa gaagaagtct
901 ggctccgaga agaacacagg gaggcctcct ggtgaggcgg cggaggaggc aaaaaagtgc
961 aggcccccaa ataagcccca gaaaggccca agccacgacc tcccccgccg gcattccatg
1021 gaccggcaga actcccagga gaaggcagtg ggtgccgcag cctacggtgc ccgttccccc
1081 ggtggctccc cgggccagtc cccacccacg ggctactcca tcctctctcc tgcccacttc
1141 agcggccccc gctcctccag atacctcggg gagttcttaa agaacgccat ccatctggag
1201 cctcacaaga aggccatggc tgggggccat gtgttcagaa atgcccactt tgattacagc
1261 cctgcggggt tggcagttca caggggggga cacttcgaca cccccgtgca gttccttcgg
1321 cggctggacc tctccgaact cctcactcac atccccaggc ataagctgaa cactttccac
1381 gtgcgcatgg aagacgatgc ccaagtgggc cagggggaag acttgcggaa gttcattctg
1441 gccgcgctca gtgccagcca cagaaacgtg gtaaactgtg ccctgtgcca ccgggcgctc
1501 ccggtgttcg aacagttccc actggtggat ggaactttgt tcctaagccc gtcgagacat
1561 gatgagatcg aatatgatgt tccttgtcac cttcaaggga gactcatgca tctgtatgcc
1621 gtgtgcgtgg actgcctgga aggggttcac aagatcatct gcatcaagtg taagtcacgg
1681 tgggatggca gctggcacca gctgggcact atgtacacct acgacatcct ggctgcctct
1741 ccatgttgtc aggcccgcct gaactgtaag cactgtggga agccggtgat cgacgtgagg
1801 atcgggatgc agtacttctc cgaatatagc aacgtccagc agtgtccaca ctgtgggaac
1861 ctggactacc acttcgtgaa gccattttcc tccttcaaag ttctcgaagc ttattgatga
1921 aagctttgct ttagtaatag ctattttatt gatattatta ctttattaca tatcttttat
1981 agggaaacat tctgtgacat taatttcctt tctaatttaa aggagagtta ctttgttgta
2041 tgtgtgccac taaaataggg gctgcccttg ccctgtcttg attcccgagt gttaatctgt
2101 ggttttgacc agagcccaga tgggtaatcc tgtgcatttg ggttggggtt cactcttacc
2161 aagaatcttt gatgcagctt taagatggtg gggaggatgg ggtgaattta ggaaaggaat
2221 ttgtggttat aaactaagag cttgatagga gttggaagga aactcttact aaaatgttaa
2281 ctttctaaaa accttctttt agatcttcct tgggcctttg gaaaaatatg tgacaagtga
2341 atgtaagtct gtgcctggag agctaatagt gcattagtct atctcagcct agtgttctgc
2401 agcacacatg ggcaggcagt ttactcacac tgacaggtga cctgaaagtg gcacaagtgc
2461 tgtttctatc actattgtaa tttgccagtt catttttcat gctgaaagta atatccaaat
2521 tgtaagacat atgaaagata ttagtgttgc aaatatgttt aggtaaactg acctataaca
2581 gaatatgtga aatgaatttg gaaataatgc aagaaggcag aactcaatca tttaaattgt
2641 gtctttgaag ttggtaatat agcttttaag gagaacccat gaataacctg atttgggcag
2701 tgatgattta ttacaggttg cactgttgaa gtgtcatttg gtgtcaggtt cttctcacag
2761 gtaaatcttt cagccacaga atctaactgg tgagcttcag aaccaataat tgccacattt
2821 attgtcctca aaattgctta tggccatgtt taaccaatta attctgagtt tccaaaatca
2881 aagatttgac cttaagaggg aagggaaaaa agtgtgaaag gatgatgaag aaaataattt
2941 tactatttct tttaaaagta tgttttggaa aatcaatgat tttaatgcat agcagtatgt
3001 ttgaaaaata gaccattcta aaaagcccat gataccttac tgttgatgaa aaaggatgat
3061 catatatata gaacttgatt agtcagagca ttgggcattc caaaatacag cctttggttc
3121 agtagatttt aatgctttaa atagactgac gtcgcatacc cttatagaat tggaatatga
3181 tttctcaaaa attaatttga taatttcatg tatgatgtgc atatatgcta aaagaatgca
3241 gaaaatcatt ttatgaatag ccaaatttgg ggttgatgtg aacattttat gttactcatt
3301 tggtttatac tttttttttt ttttttttaa ctgtgtggtt tttcttttca gaagtattta
3361 ggcaatattg cacgtgagtt tcagttcttt ttttcttttt tttgagatgg agtctcactc
3421 ttgtcaccca ggctggagtg cagtagtgcg atctcagctc actgcaacct ctgcctcctg
3481 gattcaagcg attctcctgt cccagcctcc caggtagctg ggactatagg cacgtgccac
3541 cacacccggc taattttttg tatttttagt agagacagcg tttcaccatg ttagctagga
3601 tggtctagat ctcctgacct tgtgatctgc ctgcctcggc ctcccaaagt gctgggatta
3661 caggcgtgag tcactgcgcc tggccaagtt tcagttctat atgaagtatt tgatgttttg
3721 tttgaaacaa tacagcatta aagaaccaat gttattcact aatatcattc atctttcagt
3781 ttggatgatt tggtttgctg catctaggtc ggtgtttgat catctgaaaa aacatttcag
3841 tgggaagaaa tgcataaaat gcctataaga agtagaaagt cattgaactg acagtgtttg
3901 atgcaactaa aagaggattg taagcatagc tttctgcaaa cttgtcttta atgcacaaag
3961 ctgtagtggt gaattaacta tctccttatt gattctctcc tgtacccaga tgcaaaaagt
4021 gctaagtttc tcttgtcctc gtaataccat ttggatttta tttctgaatt taaatagtaa
4081 aatatttatg atgctgatct ttaacccacc taaaatttta tagtgaaacc tgctttatat
4141 tgttgttctg aagcttacaa ttgacctata cattgcattc agcaagctcc tgaatttaga
4201 actgccgtca gtgtagtgta tgctgtgttc catgttgcct ttttagatgg ctttctaccc
4261 cctgaacaat aaataggatg aggttttact gtaattgggt aaagtttact cttggacatt
4321 atttcgatgc taaagtaagg attctgtgga tgttacttaa agagaaaagc ataagagcat
4381 gaagcatatc tgggaatatc ttttgccttt aagacgattc attcttgtct agagggaaaa
4441 tctggctgat ttgggaataa aatataatcg aatattcaac accatgaaga taaatcttat
4501 tttggaaatc tactgacctt aataccccaa gcttgccctg aatactttga ttggaattgg
4561 aatatatcaa aaaaggttag tatttttgtt gtagttagga tactaaaagg atattagtta
4621 cccaagagat ccaatttgtt tttctgatga atagtgttca gtaaaatgaa gcagtcttaa
4681 gagtgactaa taatttcaaa gtgatttttc gtctattctt aatatttttt aattatttat
4741 ttttaagagt tttatacctt gagcagatac aatgatctgc tttagtgaga ggacaatttc
4801 tgattgattg ttttctcttc aggccatctc acctcttcat tctcttgtta catttgaagc
4861 agttgatata atgggtttat actttaaaag atagacatgg tgccatgaag ttggggagtt
4921 gggtgaatta tcccattcta gttacagagg agctttcctt aaatgccctt taacttctag
4981 gttttgttca agaagttcat tttctgagta aaagttattt tcatatatgt tgggggaaaa
5041 ttaactcatc taaaaagaat cttattaggt atttgaactc taaaactaac agataagaca
5101 gatatgtacc ttattagagc accagaacta atttgctaag tcttttgttt agtcctgcaa
5161 gactgatgct taatacacag tctgttctcc tgtgtctagg tcaggaactc cagtttgctt
5221 ttctgttttg tgtcctggta gcagctgttg agtaactttc attggaggtt gggaaggaag
5281 tgaggagaaa gtgttcttgt ttagtgtttt atttcctata ataggatgct gcctaaccca
5341 gttcatctct atgtcctgtt cactgaatat tccgggtaat tgaaagaaaa tataatggat
5401 gggctccatt aaaaccagct caaaaataaa ttcttgtcag taaagatttc ttgtcaagat
5461 gtcttggatt gcacttttgt tgaggaaaga cagtgtaaat agttaaagaa tgttgataaa
5521 attgaaacat ttggttgtgg aattgtgtgt ggttttagag ggtttctgtt tgtgaaatgt
5581 atgtattaaa aataataaaa ttccagaaac taaaaaaaaa aaaaaaaaaa aaaa
//