LOCUS AB028019 3412 bp mRNA linear HUM 19-NOV-2004
DEFINITION Homo sapiens HsLATS2 mRNA for large tumor suppressor 2, partial
cds.
ACCESSION AB028019
VERSION AB028019.1
KEYWORDS HsLats2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3412)
AUTHORS Nojima,H. and Nishiguchi,H.
TITLE Direct Submission
JOURNAL Submitted (27-MAY-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Hiroshi Nojima
Research Institute for Microbial Diseases, Osaka University,
Department of Molecular Genetics; Yamadaoka 3-1, Suita, Osaka
565-0871, Japan
REFERENCE 2
AUTHORS Yabuta,N., Fujii,T., Copeland,N.G., Gilbert,D.J., Jenkins,N.A.,
Nishiguchi,H., Endo,Y., Toji,S., Tanaka,H., Nishimune,Y. and
Nojima,H.
TITLE Structure, expression, and chromosome mapping of LATS2, a
mammalian homologue of the drosophila tumor suppressor gene
lats/warts
JOURNAL Genomics 63, 263-270 (2000)
COMMENT
FEATURES Location/Qualifiers
source 1..3412
/db_xref="H-InvDB:HIT000058917"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS <1..3143
/codon_start=3
/gene="HsLATS2"
/product="large tumor suppressor 2"
/protein_id="BAA92381.1"
/transl_table=1
/translation="NSDTSLDAKVLGSKDATSSKQQMRATPKFGPYQKALREIRYSLL
PFANESGTSAAAEVNRQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLD
PRNEQIVRVIKQTSPGKGLMPTPVTRRPSFEGTGDSFASYHQLSGTPYEGPSFGADGP
TALEEMPRPYVDYLFPGVGPHGPGHQHQHPPKGYGASVEAAGAHFPLQGAHYGRPHLL
VPGEPLGYGVQRSPSFQSKTPPETGGYASLPTKGQGGPPGAGLAFPPPAAGLYVPHPH
HKQAGPVAHQLHVLGSRSQVFASDSPPQSLLTPSRNSLNVDLYELSSTSVQQWPAATL
ARRDSLQKPGLEAPPRAHVAFRPDCPVPSRTNSFNSHQPRPGPPGKAEPSLPAPNTVT
AVSAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAPAPAPAPAPAPAAEGLDAKEEHA
LALGGAGAFPLDVEYGGPDRSARLRPTRSTCCCAKSEQYDLDSLCAGMEQSLRAGPNE
PEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRKNSRDEEKRESRIKSYSPYAFKFFMEQ
HVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKS
MFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEAD
NEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESV
HKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSD
LWDDVSNCRCGDRLKTLEQRARKQHQRSLAHSLVGTPNYIAPEVLLRKGYTQLCDWWS
VGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSAD
HRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDA
SEGSTKAWDTLTSPNNKHPEHAFYEFTFRRFFDDNGYPFRCPKPSGAEASQAESSDLE
SSDLVDQTEGCQPVYV"
regulatory 3364..3369
/regulatory_class="polyA_signal_sequence"
BASE COUNT 801 a 1066 c 975 g 570 t
ORIGIN
1 caaacagtga cacttccctg gatgccaaag tcctggggag caaagatgcc accagcagca
61 agcagcagat gagagccacc ccaaagttcg gaccttatca gaaagccttg agggaaatca
121 gatattcctt gttgcctttt gctaatgaat cgggcacctc tgcagctgca gaagtgaacc
181 ggcaaatgct gcaggaactg gtgaacgcag gatgcgacca ggagatggct ggccgagctc
241 tcaagcagac tggcagcagg agcatcgagg ccgccctgga gtacatcagc aagatgggct
301 acctggaccc gaggaatgag cagattgtgc gggtcattaa gcagacctcc ccaggaaagg
361 ggctcatgcc aaccccagtg acgcggaggc ccagcttcga aggaaccggc gattcgtttg
421 cgtcctacca ccagctgagc ggtaccccct acgagggccc aagcttcggc gctgacggcc
481 ccacggcgct ggaggagatg ccgcggccgt acgtggacta ccttttcccc ggagtcggcc
541 cccacgggcc cggccaccag caccagcacc cacccaaggg ctacggtgcc agcgtagagg
601 cagcaggggc acacttcccg ctgcagggcg cgcactacgg gcggccgcac ctgctggtgc
661 ctggggaacc cctgggctac ggagtgcagc gcagcccctc cttccagagc aagacgccgc
721 cggagaccgg gggttacgcc agcctgccca cgaagggcca gggaggaccg ccaggcgccg
781 gcctcgcttt cccaccccct gccgccgggc tctacgtgcc gcacccacac cacaagcagg
841 ccggtcccgt ggcccaccag ctgcatgtgc tgggctcccg cagccaggtg ttcgccagcg
901 acagcccccc gcagagcctg ctcactccct cgcggaacag cctcaacgtg gacctgtatg
961 aattgagcag cacctccgtc cagcagtggc cggctgccac cctggcccgc cgggactccc
1021 tgcagaagcc gggcctggag gcgccgccgc gcgcgcacgt ggccttccgg cctgactgcc
1081 cagtgcccag caggaccaac tccttcaaca gccaccagcc gcggcccggt ccgcctggca
1141 aggccgagcc ctccctgccc gcccccaaca ccgtgacggc tgtcagcgcc gcgcacatct
1201 tgcacccggt gaagagcgtg cgtgtgctga ggccggagcc gcagacggct gtggggccct
1261 cgcaccccgc ctgggtgccc gcgcctgccc cggcccccgc ccccgccccc gccccggctg
1321 cggagggctt ggacgccaag gaggagcatg ccctggcgct gggcggcgca ggcgccttcc
1381 cgctggacgt ggagtacgga ggcccagacc ggagtgcccg cctccgccct acccgaagca
1441 cctgctgctg cgcaaagtcg gagcagtacg acctggacag cctgtgcgca ggcatggagc
1501 agagcctccg tgcgggcccc aacgagcccg agggcggcga caagagccgc aaaagcgcca
1561 agggggacaa aggcggaaag gataaaaagc agattcagac ctctcccgtt cccgtccgca
1621 aaaacagcag agacgaagag aagagagagt cacgcatcaa gagctactcg ccatacgcct
1681 ttaagttctt catggagcag cacgtggaga atgtcatcaa aacctaccag cagaaggtta
1741 accggaggct gcagctggag caagaaatgg ccaaagctgg actctgtgaa gctgagcagg
1801 agcagatgcg gaagatcctc taccagaaag agtctaatta caacaggtta aagagggcca
1861 agatggacaa gtctatgttt gtcaagatca aaaccctggg gatcggtgcc tttggagaag
1921 tgtgccttgc ttgtaaggtg gacactcacg ccctgtacgc catgaagacc ctaaggaaaa
1981 aggatgtcct gaaccggaat caggtggccc acgtcaaggc cgagagggac atcctggccg
2041 aggcagacaa tgagtgggtg gtcaaactct actactcctt ccaagacaaa gacagcctgt
2101 actttgtgat ggactacatc cctggtgggg acatgatgag cctgctgatc cggatggagg
2161 tcttccctga gcacctggcc cggttctaca tcgcagagct gactttggcc attgagagtg
2221 tccacaagat gggcttcatc caccgagaca tcaagcctga taacattttg atagatctgg
2281 atggtcacat taaactcaca gatttcggcc tctgcactgg gttcaggtgg actcacaatt
2341 ccaaatatta ccagaaaggg agccatgtca gacaggacag catggagccc agcgacctct
2401 gggatgatgt gtctaactgt cggtgtgggg acaggctgaa gaccctagag cagagggcgc
2461 ggaagcagca ccagaggtcg ctggcacatt cactggtggg gactccaaac tacatcgcac
2521 ccgaggtgct cctccgcaaa gggtacactc aactctgtga ctggtggagt gttggagtga
2581 ttctcttcga gatgctggtg gggcagccgc cctttttggc acctactccc acagaaaccc
2641 agctgaaggt gatcaactgg gagaacacgc tccacattcc agcccaggtg aagctgagcc
2701 ctgaggccag ggacctcatc accaagctgt gctgctccgc agaccaccgc ctggggcgga
2761 atggggccga tgacctgaag gcccacccct tcttcagcgc cattgacttc tccagtgaca
2821 tccggaagca gccagccccc tacgttccca ccatcagcca ccccatggac acctcgaatt
2881 tcgaccccgt agatgaagaa agcccttgga acgatgccag cgaaggtagc accaaggcct
2941 gggacacact cacctcgccc aataacaagc atcctgagca cgcattttac gaattcacct
3001 tccgaaggtt ctttgatgac aatggctacc cctttcgatg cccaaagcct tcaggagcag
3061 aagcttcaca ggctgagagc tcagatttag aaagctctga tctggtggat cagactgaag
3121 gctgccagcc tgtgtacgtg tagatggggg ccaggcaccc ccaccactcg ctgcctccca
3181 ggtcagggtc ccggagccgg tgccctcaca ggccaatagg gaagccgagg gctgttttgt
3241 tttaaattag tccgtcgatt acttcacttg aaattctgct cttcaccaag aaaacccaaa
3301 caggacactt ttgaaaacag gactcagcat cgctttcaat aggcttttca ggaccttcac
3361 tgcattaaaa caatattttt gaaaaattta aaaaaaaaaa aaaaaaaaaa aa
//