LOCUS AB026543 1509 bp mRNA linear HUM 03-JUL-1999
DEFINITION Homo sapiens WAVE3 mRNA for WASP-family protein, complete cds.
ACCESSION AB026543
VERSION AB026543.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1509)
AUTHORS Suetsugu,S., Miki,H. and Takenawa,T.
TITLE Direct Submission
JOURNAL Submitted (22-APR-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Shiro Suetsugu
Institute of Medical Science, Unversity of Tokyo, Department of
Biochemistry; 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan
REFERENCE 2
AUTHORS Suetsugu,S., Miki,H. and Takenawa,T.
TITLE Identification of two human WAVE/SCAR homologues as general actin
regulatory molecules which associate with the Arp2/3 complex
JOURNAL Biochem. Biophys. Res. Commun. 260, 296-302 (1999)
COMMENT
FEATURES Location/Qualifiers
source 1..1509
/chromosome="13"
/db_xref="H-InvDB:HIT000058860"
/db_xref="taxon:9606"
/map="13q12"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="brain"
CDS 1..1509
/codon_start=1
/function="associates with Arp2/3 complex and regulates
actin cytoskeleton"
/gene="WAVE3"
/product="WASP-family protein"
/protein_id="BAA81796.1"
/transl_table=1
/translation="MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSL
SKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFK
SSTVQDQQVVSKNSIPNPVADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDL
WKEKMLQDTEDKRKEKRRQKEQKRIDGTTREVKKVRKARNRRQEWNMMAYDKELRPDN
RLSQSVYHGASSEGSLSPDTRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHG
PASQAAEHEYRPPSASARHMALNRPQQPPPRRPPQAPEGSQASAPMAPADYGMLPAQI
IEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLV
TAPPPPGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRM
GIQLKKVQEQREQEAKREPVGNDVATILSRRIAVEYSDSDDDSEFDENDWSD"
BASE COUNT 388 a 469 c 365 g 287 t
ORIGIN
1 atgcctttag tgaagaggaa cattgagccc cggcacttgt gccggggagc tctgcctgaa
61 gggattacca gcgaacttga atgtgtaacc aatagtactc ttgccgctat catacgccag
121 ctgagcagtc tgagcaaaca tgctgaagac atatttggtg agttgtttaa tgaggctaac
181 aacttctaca tcagagcaaa ttctcttcaa gacagaattg atcgccttgc tgtcaaagtc
241 acccagctgg attcaacagt ggaagaggtc tcactacagg atatcaacat gaaaaaagct
301 ttcaaaagtt ccacagtcca agaccagcaa gtggtttcaa agaacagcat tcctaatcct
361 gttgctgata tttacaacca gagtgataag ccaccgcctc tgaacatcct gacaccatac
421 agagatgaca agaaggatgg gctgaagttc tatactgatc cttcctattt ctttgacctc
481 tggaaagaaa aaatgctaca ggacacagaa gacaaaagga aagagaaaag gcgtcaaaag
541 gagcaaaagc gtatagatgg caccacccgt gaggtgaaaa aggttagaaa agccagaaac
601 aggcgccagg agtggaatat gatggcatat gacaaagagc ttagacccga caacaggttg
661 tctcagagtg tgtaccatgg agcgtcttcc gagggatccc tgtccccaga tactaggtca
721 catgcatcgg acgttacgga ttactcttac ccggctactc ccaaccattc tctgcacccc
781 cagcctgtga ccccttccta tgcagctggt gacgtgccac cacacgggcc tgcaagccag
841 gctgcggagc atgagtaccg gcccccatct gcctcggcga ggcacatggc cctcaacaga
901 cctcagcagc cgcccccccg gcgtccccct caggccccag aggggtccca ggcctctgca
961 ccgatggctc cagcagacta cgggatgctc ccagcgcaga taattgagta ttacaaccca
1021 tccggaccac ctcctccgcc acctcctcct gtgattccct cagcacaaac tgccttcgtc
1081 agccctctcc agatgcccat gcagcccccg ttccctgcat cagccagctc cacgcacgca
1141 gctcctcctc acccaccctc caccgggctc ctggtcacag ccccgccacc cccgggccca
1201 ccacctcccc cgccaggccc tcctggtccc gggtcttctc tttcgtcctc cccaatgcat
1261 ggccccccag tagctgaggc gaagcggcaa gagcctgcac agccaccaat cagtgatgct
1321 cgaagcgacc tcctcgctgc tattcgaatg ggaattcaac tgaaaaaggt gcaggagcag
1381 cgggagcagg aggccaagcg ggagccagtg gggaatgacg tggccacgat cctgtcccgg
1441 cgcattgccg tggagtacag cgactctgac gacgactcag agttcgacga gaacgactgg
1501 tccgactga
//