LOCUS AB024327 1864 bp mRNA linear HUM 20-DEC-2000
DEFINITION Homo sapiens pt-wd mRNA for WD-40 repeat protein, complete cds.
ACCESSION AB024327
VERSION AB024327.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1864)
AUTHORS Matsuda,S. and Okuda,T.
TITLE Direct Submission
JOURNAL Submitted (25-FEB-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Satoru Matsuda
Nagoya University School of Medicine, Molecular Pathogenesis; 65
Tsurumai-cho Showa-ku, Nagoya 466-8550, Japan
REFERENCE 2
AUTHORS Matsuda,S., Katsumata,R., Okuda,T., Yamamoto,T., Miyazaki,K.,
Senga,T., Machida,K., Thant,A.A., Nakatsugawa,S. and Hamaguchi,M.
TITLE Molecular Cloning and Characterization of Human MAWD, a Novel
Protein Containing WD-40 Repeats Frequently Overexpressed in
Breast Cancer
JOURNAL Cancer Res. 60, 13-17 (2000)
COMMENT
FEATURES Location/Qualifiers
source 1..1864
/cell_line="HepG2"
/db_xref="H-InvDB:HIT000058778"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="liver"
CDS 301..1353
/codon_start=1
/function="putative TGF-beta receptor association"
/gene="pt-wd"
/note="homologous to TGF beta-receptor interacting
protein-1 (TRIP-1)"
/product="WD-40 repeat protein"
/protein_id="BAA75544.1"
/translation="MAMRQTPLTCSGHTRPVVDLAFSDITPYGYFLISACKDGKPMLR
QGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHI
VKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS
ADDKTVRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIK
SFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPD
GELYASGSEDGTLRLWQTVVGKTYGLWKCVLPEEDSGELAKPKIGFPETTEEELEEIA
SENSDCIFPSAPDVKA"
BASE COUNT 528 a 388 c 424 g 524 t
ORIGIN
1 cggtgtggac gcatgtgaat cgtggctggc ccggttctcc gcttctcccc atcccctact
61 ttcctccctc cctccctttc cctccctcgt cgactgttgc ttgctggtcg cagactccct
121 gacccctccc tcacccctcc ctaacctcgg tgccaccgga ttgcccttct tttcctgttg
181 cccagcccag ccctagtgtc agggcggggg cctggagcag cccgaggcac tgcagcagaa
241 gagagaaaag acaacgacga ccctcagctc gccagtgcgg tcgctggctt cgccgccgcc
301 atggcaatga gacagacgcc gctcacctgc tctggccaca cgcgacccgt ggttgatttg
361 gccttcagtg acatcacgcc ttatgggtat ttcttaatca gcgcttgcaa agatggtaaa
421 cctatgctac gccagggaga tacaggagac tggattggaa catttttggg tcataaaggt
481 gctgtttggg gtgcaacact gaataaggat gccaccaaag cagctacagc agctgcagat
541 ttcacagcca aagtgtggga tgctgtctca ggagatgaat tgatgaccct ggctcataaa
601 cacattgtca agactgtgga tttcacgcag gatagtaatt atttgttaac cgggggacag
661 gataaactgt tacgcatata tgacttgaac aaacctgaag cagaacctaa ggaaattagt
721 ggtcatactt ctggtataaa aaaagctctg tggtgcagtg aggataaaca gattctttct
781 gctgatgaca aaactgttcg actttgggat catgctacta tgacagaagt gaaatctcta
841 aattttaata tgtctgttag tagtatggaa tatattcctg agggagagat tttggttata
901 acttatggac gatctattgc ttttcatagt gcagtaagtt tggacccaat taaatccttt
961 gaagctcctg caaccatcaa ttctgcatct cttcatcctg agaaagaatt tcttgttgca
1021 ggcggtgaag attttaaact ttataagtat gattataata gtggagaaga attagaatcc
1081 tacaagggac actttggtcc tattcactgt gtgagattta gtcctgatgg agaactctat
1141 gccagtggtt cagaagatgg aacattgaga ctatggcaaa ctgtggtagg aaaaacgtat
1201 ggcctttgga aatgtgtgct tcctgaagaa gatagtggtg agctggcaaa gccaaagatt
1261 ggttttccag agacaacaga agaggagcta gaagaaattg cttcagagaa ttcagattgc
1321 atctttcctt cagctcctga tgttaaggcc tgagcgtcaa tcatatgttg cagttagtat
1381 acaactgact aaaacaagca agcagagaaa agcatcagcc ttccagagtt actgtctgct
1441 taaggcagaa acagcagtaa ataatgagga aaatgaatta gctccagtgc tggaacaact
1501 aactaacttg gtgttacctg taagtgaaaa ctcaagtgtc agatgaaggg aggtggagtt
1561 atcctcttat agtacagtgg cctgttatct ttttaatgaa tatatacaag ccaacatcca
1621 atttctatta ttacaattag ggttcttgta gctgtttatg ttaatatgga gaagaaaact
1681 atattggctg attttttctg atcttaaagc agaatgcctt ttcttttttt gcttcagttg
1741 taaagaagag ggaatacatg ataaagtaac tggtttgatt tctcgttcat tgtacactgc
1801 ctctgaacat ctaattgttt ttagttgtct aaataaaatg cctctaaaac aaaaaaaaaa
1861 aaaa
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