LOCUS AB024057 4404 bp mRNA linear HUM 29-JUN-1999
DEFINITION Homo sapiens VRP mRNA for vascular Rab-GAP/TBC-containing protein,
complete cds.
ACCESSION AB024057
VERSION AB024057.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4404)
AUTHORS Yonekura,H. and Yamamoto,H.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-1999) to the DDBJ/EMBL/GenBank databases.
Contact:Hideto Yonekura
Kanazawa University, Department of Biochemistry, School of
Medicine; Takara-machi 13-1, Kanazawa, Ishikawa 920-8640, Japan
REFERENCE 2
AUTHORS Yonekura,H., Migita,H., Sakurai,S., Wang,H., Harada,S.,
Abedin,M.J., Yamagishi,S. and Yamamoto,H.
TITLE Antisense display-a method for functional gene screening:
evaluation in a cell-free system and isolation of
angiogenesis-related genes
JOURNAL Nucleic Acids Res. 27, 2591-2600 (1999)
COMMENT
FEATURES Location/Qualifiers
source 1..4404
/cell_type="Microvascular endothelial"
/db_xref="H-InvDB:HIT000058774"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 1118..3811
/codon_start=1
/gene="VRP"
/note="full length AD3"
/product="vascular Rab-GAP/TBC-containing protein"
/protein_id="BAA75489.1"
/transl_table=1
/translation="MEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFF
RAFFRLPRKEKLHAVVDCSLWTPFSRCHTAGRMFASDSYICFASREDGCCKIILPLRE
VVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYD
TSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSG
SQSPDSRMSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFS
DAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVL
TAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVD
QSVFEELIKGHLPELAEHMNDLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGI
KAIFQLGLAVLEANAEDLCSSKDDGQALMILSRFLDHIKNEDSPGPPVGSHHAFFSDD
QEPYPVTDISDLIRDSYEKFGDQSVEQIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPE
VSILPEDLEELYDLFKREHMMSCYWEQPRPMASRHDPSRPYAEQYRIDARQFAHLFQL
VSPWTCGAHTEILAERTFRLLDDNMDQLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHI
PPALTENDRDSQSPLRNPLLSTSRPLVFGKPNGDAVDYQKQLKQMIKDLAKEKDKTEK
ELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSCS
QECGEELRASAPSPEDSVFADTGKTPQDSQALPEAAERDWTVSLEHILASLLTEQSLV
NFFEKPLDMKSKLENAKINQYNLKTFEMSHQSQSELKLSNL"
regulatory 4383..4388
/regulatory_class="polyA_signal_sequence"
polyA_site 4404
BASE COUNT 1074 a 1149 c 1166 g 1015 t
ORIGIN
1 actcggccgg cagcggaccg cagccaccag ccgcccgcgc cctccagccc cgtccgggag
61 tccccggccc gctgcggtgc cgtgagtacc tccaaccccc tgcgccccgg aggaggccga
121 ggggcttagc caccagggct cggaagtggg ggccgaatcc ggtgcgagac ccaaggagag
181 gggagcagag ccggagttgg ggagactgtg gctgaaaact gtgtcttcct ggagactagg
241 ctggcatttt gactttgggg ttgctgaaaa gccaggagtc aaaatgactg agcgctttga
301 ctgccaccat tgcaacgaat ctctctttgg caagaggtac atcctgcggg aggagagccc
361 ctactgcgtg gtgtgctttg agaccctgtt cgccaacacc tgcgaggagt gtgggaagcc
421 catcggctgt gactgcaagg tgcaacatta gaggaaatca atcagcactg ggactggctg
481 gaacaaaatc tcctccacac cttgtctgtc tttgataata aagatgacat tgccagtttt
541 gtcaaaggga aggtaaagcc gtgtgtctgg gtggctgacg gatgacacag ctgagccatt
601 ctcctcatca ggtgtgactg tcgttgaagc agcgcacact tctcgggggc ctgtgcacct
661 cagtccctcc tgcttcctgt cccttgcacc ccctgccttc ccattgctgg ctcactgagc
721 agggactgtc atctctgtgt gtcaggctct gatagccgag gagaccagca gcaggctcgc
781 cgagcaggag gaggaacccg agaaattccg agaagccctg gtgaagttcg aggccaggtt
841 caacttcccc gaggcggaga agctggtcac ctactactcc tgctgctgtt ggaagggcag
901 ggtgccccgc cagggctggc tgtacctcag catcaaccac ctctgcttct actccttctt
961 cctgggcaag gaacttaaac ttgtggttcc gtgggttgat atccagaaat tagaaagaac
1021 gtccaatgtc tttctgacgg ataccatccg aatcaccacg cagaataagg agcgtgactt
1081 ctccatgttc ctgaacctgg atgaggtgtt taaggtcatg gagcagctgg ccgacgtgac
1141 gctgcgaagg ctgctggata atgaggtctt tgacctcgac cccgatctgc aggagccgag
1201 ccagatcacc aagagggacc tggaagccag agcacagaat gagttcttcc gggctttctt
1261 caggttgccg aggaaggaga agctgcacgc ggttgtggac tgttcgctct ggacgccgtt
1321 cagtcgctgt cacaccgcgg ggcggatgtt cgcctctgac agctacatct gctttgccag
1381 cagagaagat ggctgctgta agatcatcct gccactcaga gaggtggtga gcatcgagaa
1441 gatggaggac acgagcctgc tgccgcatcc catcattgtc agtatcagaa gcaaggtggc
1501 cttccagttc attgagctcc gggaccgaga cagcctggtg gaggcgctgc ttgcgaggtt
1561 gaagcaggtc cacgccaacc accccgtgca ctacgacacc tctgcggatg atgacatggc
1621 ttcactcgtg tttcattcaa caagcatgtg cagtgaccac agatttgggg atcttgaaat
1681 gatgtcttct caaaatagcg aggagagtga gaaagagaag agcccgctga tgcaccccga
1741 tgccctggtc accgccttcc agcagtcagg cagccagagc cctgactccc gaatgtccag
1801 agaacagata aaaataagcc tgtggaatga ccactttgtg gaatacggca gaaccgtgtg
1861 tatgtttcgc acagagaaga ttcggaagct cgtagccatg ggcatccctg aatctttgcg
1921 agggagactc tggcttctct tctcagatgc ggtgacggat cttgcctcac accctggtta
1981 ctacgggaat ctggtggagg agtccctggg gaaatgctgc ctggtaaccg aggagataga
2041 acgagacctg caccgctccc tgccagagca ccccgccttc cagaacgaaa cgggaattgc
2101 tgctttgagg agagtcttga cggcctatgc ccaccggaac cccaagattg gatactgcca
2161 gtccatgaac atcctgacct ccgtgctgct gctgtacacc aaggaggagg aagccttctg
2221 gctgttggtt gctgtgtgtg agcggatgct gcccgattac ttcaaccacc gagtgatcgg
2281 ggcacaagtt gaccagtctg tcttcgagga gctcatcaag ggtcatctcc cagagctggc
2341 agagcacatg aacgacctct cagccctggc gtctgtctct ctctcgtggt tcctgaccct
2401 gttcctcagc atcatgcctc tagagagtgc ggtgaatgtg gtagactgct tcttctatga
2461 tggcatcaaa gccatcttcc agctgggact ggctgtgctt gaggccaatg ctgaggacct
2521 gtgcagcagc aaggatgatg gccaggcctt gatgatcctc agcaggtttc tagatcacat
2581 taagaatgag gacagcccag ggcccccagt tggcagccac catgcctttt tctccgacga
2641 ccaggagccc taccctgtga ctgatatttc ggacctgatc cgggattcct atgagaaatt
2701 tggagaccag tctgtggagc agatcgagca cctacgttac aagcacagga tcagggtcct
2761 ccaaggccac gaggacacca caaagcagaa cgtgcttcga gtcgttatcc cggaagtctc
2821 aattcttcct gaagacctag aggagctcta cgacttattc aagagagaac atatgatgag
2881 ctgttactgg gagcagccca ggcccatggc ctcacgccac gaccccagcc ggccctatgc
2941 tgagcagtac cgcatagacg cccggcagtt tgcacacctg tttcagctag tctcgccctg
3001 gacctgcggg gcccacacgg agatcctcgc cgaaaggacg ttcaggctct tggatgacaa
3061 catggaccag ctcatcgagt tcaaagcgtt tgtgagctgc ctcgatatta tgtataatgg
3121 agaaatgaat gagaagatta aactattata caggcttcat atccctccag cactcactga
3181 aaatgaccga gacagccagt cgccgttgag gaatcctctg ttgtcaacat cgagacccct
3241 ggttttcggg aaacccaatg gtgatgcagt tgattatcag aaacagctga agcagatgat
3301 taaggattta gccaaagaaa aagataaaac tgagaaagaa ttgcccaaaa tgagccagag
3361 agaatttatc cagttctgta aaactctgta cagtatgttc catgaagatc cagaagaaaa
3421 tgatttgtat caagccatcg ccacagtcac cacactgctg ctgcagatcg gggaggtggg
3481 gcagcgaggc agcagctctg gaagctgctc ccaggagtgt ggggaggagc tgcgggcttc
3541 agctccttct cctgaggact cggtttttgc agacactggg aagacgcccc aggactccca
3601 ggcacttcca gaggcggcag aaagggactg gactgtctcc cttgaacata ttttagcttc
3661 acttctgact gaacagtcat tagtcaactt ttttgaaaag ccactggaca tgaaatccaa
3721 acttgaaaat gccaagatca atcagtacaa tctcaaaact tttgaaatga gccaccaatc
3781 acaatctgaa cttaagctga gtaacttgta gcaagacagc agctgctatg cacactggag
3841 tccaccatac caaagcacga accagactgt ttcttggggt cagccctaaa ccgagatttc
3901 agtctacctt accaatgggg catctggcta aacaacctga caaactgtgg ccaggggaac
3961 cgacacaacc ctcaagcatt tctatgtatt gagaattgtc agtgccctaa ggtatccatt
4021 ggttcccttg atgccaactt acaattttta ccggatttgc tgaaatgggc acttctgctg
4081 tgatgctagt gttgattttg ctctcagatg aacacaatgt ctcatactaa ccaagaagca
4141 agaaaagccc catgctttca tttttcactt ggagtgacaa tgggagaggt caggaatcaa
4201 gttcactttc aagatctaag ggagtccact atctgtgcaa ttgtatttgg cttttttttg
4261 cactgtttca atgctggtaa ttgaaaccat tttaatatat ttggttgtat tcactttata
4321 tgtccttcca aaaatgttgt tgtgtacata ccatgctttc aatgttggct tccaagtttt
4381 ttaataagaa actttttgtt tttt
//