LOCUS AB020522 5615 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens DLEC1 mRNA, complete cds.
ACCESSION AB020522
VERSION AB020522.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5615)
AUTHORS Nakamura,Y.
TITLE Direct Submission
JOURNAL Submitted (27-NOV-1998) to the DDBJ/EMBL/GenBank databases.
Contact:Yusuke Nakamura
Institute of Medical Science, The University of Tokyo, Laboratory
of Molecular Medicine, Human Genome Center; 4-6-1 Shirokanedai,
Minato-ku, Tokyo 108-8639, Japan
REFERENCE 2
AUTHORS Daigo,Y., Nishiwaki,T., Kawasoe,T., Tamari,M., Tsuchiya,E. and
Nakamura,Y.
TITLE Molecular cloning of a candidate tumor suppressor gene, DLC1, from
chromosome 3p21.3.
JOURNAL Cancer Res. 59, 1966-1972 (1999)
COMMENT
FEATURES Location/Qualifiers
source 1..5615
/chromosome="3"
/db_xref="H-InvDB:HIT000058632"
/db_xref="taxon:9606"
/map="3p21.3"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 22..5289
/codon_start=1
/gene="DLEC1"
/gene_synonym="DLC1"
/note="candidate tumor suppressor gene"
/protein_id="BAA77247.1"
/standard_name="deleted in lung and esophageal cancer 1"
/transl_table=1
/translation="METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSS
LYSSLAYSEAFHYSFAARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRN
LYSAEVIGDEVSASLIKARGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQ
ARAIAENERVMSQAGVQDLESLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVP
FHSAPKGISLPGCSKLTFSCEKRSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTW
NLTPKAKERTREPLKKASQPRNKNWMNHLRVPQRELDRLLLARMESRNHFLKNPRFFP
PNTRYGGKSLVFPPKKPAPIGEFQSTEPEQSCADTPVFLAKPPIGFFTDYEIGPVYEM
VIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVAPGMTCQYIVQFFPDCLGDF
DDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGVKMTRFICKNVGFSVG
RFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFELAPGHAILVEVLFSPKSLGKA
EQTFIIMCDNCQIKELVTIGIGQLIALDLIYISGEKSQPDPGELTDLTAQHFIRFEPE
NLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMPGETFSMDSIKCYPDKETAFSIM
PRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDV
IVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISD
CHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKG
PALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDI
EPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVYLQS
SQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSE
ECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCST
EQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLSKKT
SLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQLCID
ITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPAMR
FGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQA
GNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHE
GVPSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKV
EREIPRKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCS
GVLSELVTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEET
ASADKQLVLQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQ
NLLLEYTNQTTQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSY
WTMLMGQQEPAKAAVAFRVSPNSGLLEARSANAPPTSIALQVFFTARSSELYESTMVV
EGVLGEKSCTLRLRGQGSYDERYMLPHQP"
BASE COUNT 1317 a 1606 c 1519 g 1173 t
ORIGIN
1 gttagcggcg tctcggttgc catggagacc aggagctcca aaacgcggag gtctttagcg
61 tcccggacca acgagtgcca ggggacaatg tgggcgccaa cttcgccacc agccgggtcc
121 agcagcccca gccagcccac ctggaagtcc tccttgtatt cctccctcgc ctactctgag
181 gccttccact acagcttcgc agcccggccc cgccgcctca cgcagcttgc gctggcgcag
241 cgtcccgagc ctcagctgct tcgtctgcgc ccctcctcgc tgcgcaccca agatatctcg
301 cacttgctca ccggcgtctt ccgcaacttg tactcagccg aggtcatcgg cgacgaagtg
361 agcgcaagct tgatcaaggc ccgcggcagc gagaatgagc gccacgagga gttcgtggac
421 cagctgcagc agattcggga gctctataag cagcggctgg atgagtttga aatgttggag
481 agacatatca ctcaggccca agcacgggct attgcggaaa atgagcgggt catgagccag
541 gctggagtac aggacctcga gagccttgtc aggttgcctc cagtgaagag tgtctccaga
601 tggtgtatag acagcgagtt gctacggaaa catcatttga tctccccaga agattactac
661 accgatacag tgccgtttca ctctgcacct aaaggcatct ccctacctgg atgttcaaaa
721 ctgacattta gctgtgagaa gcgttccgtc cagaagaaag agctgaacaa gaagcttgaa
781 gattcatgca ggaagaagct tgctgagttc gaagatgagt tagaccacac tgtggacagc
841 ctgacatgga atttaactcc taaggccaaa gaaaggacca gagaacctct caagaaagca
901 agtcaaccaa ggaataaaaa ctggatgaac cacttacgtg tgccacagag agagctagac
961 agacttctgc ttgccagaat ggagagtcgg aaccacttcc taaaaaatcc ccgttttttt
1021 cctcctaaca ctcgatatgg aggcaagtct cttgtttttc ctccaaagaa gccagcaccg
1081 ataggagaat tccagagtac agagccagaa cagagttgtg ctgatactcc agtgtttcta
1141 gctaagccac caattgggtt tttcacagat tatgaaattg gtccagttta tgagatggta
1201 attgcgctgc agaacaccac cacgaccagc cgctacctgc gagtcctccc gccttccacg
1261 ccatacttcg ctctgggact ggggatgttc ccaggaaaag gtggaatggt ggctcctgga
1321 atgacctgcc agtacattgt ccagtttttt cccgactgcc ttggggattt tgatgatttt
1381 attttagtgg agacccagtc agcccacaca cttctgatcc ccctgcaggc ccggaggccg
1441 ccccccgtgc tgacattgtc accggtgttg gactgtggtt actgcctcat tgggggagtc
1501 aagatgacca gattcatctg caaaaatgtg ggtttcagtg ttggcaggtt ctgcattatg
1561 cccaaaacaa gctggccacc actaagtttc aaggccattg caaccgtcgg ctttgttgaa
1621 caacctcctt ttggaatcct gccttcggtg tttgagctgg ccccgggaca tgctatatta
1681 gtggaggtct tgttttcccc aaagagccta ggaaaggcag agcagacctt catcatcatg
1741 tgcgacaact gccagataaa ggagctggtg accataggaa ttgggcagct gattgctttg
1801 gatctgatct atatttctgg tgaaaaaagc cagccagacc ctggagagct cacagactta
1861 acagcccagc acttcatacg atttgagcct gaaaaccttc ggtccacggc taggaagcag
1921 ctgattatta gaaatgctac gcacgtggag ctggccttct actggcagat catgaagccc
1981 aacctgcagc ccctcatgcc tggagaaacc ttcagcatgg acagcatcaa gtgctacccc
2041 gacaaggaga ctgccttctc catcatgccc agaaaggggg ttctaagccc ccacacagac
2101 cacgagttca tcctgagctt ttctcctcat gagctgaggg attttcacag tgtgctccag
2161 atggtgctag aggaagtccc agagcctgta agttcagaag cggagagcct ggggcactcc
2221 tcctactctg tggatgatgt gattgtcctg gaaatcgagg tgaaaggctc agtagaacct
2281 ttccaggttc tcttagagcc atatgccctc atcatcccag gggagaacta cattgggata
2341 aatgtgaaga aggcttttaa gatgtggaac aacagcaagt cacccatcag atacctgtgg
2401 gggaagatca gcgactgcca catcattgaa gtggagcccg gcacaggggt catagagccc
2461 agtgaggtcg gggattttga gttgaacttt actgggggtg tccctggccc cacaagccag
2521 gacctgctgt gtgaaatcga agactcgccc tcgccagtgg tgttacacat tgaggctgtc
2581 tttaaggggc ctgccctcat catcaacgtc tcagcccttc agtttggtct gctccgcctg
2641 gggcagaaag ccacaaactc catccagatc cggaacgtca gccagctccc agccacatgg
2701 cgcatgaagg agagcccagt ctccctccag gaaaggcctg aggatgtgtc tcccttcgac
2761 attgagcctt cgagtggcca gcttcactct ctgggggagt gcagggtgga catcaccttg
2821 gaggccctgc actgccagca tctggagacc gtcctggagc tggaggtgga aaatggtgcc
2881 tggagctacc ttcctgtgta tgctgaggta cagaagcccc atgtgtacct acagagcagc
2941 caggtggagg ttagaaatct ctacctgggt gtgcccacga agacaaccat cacacttatc
3001 aatggcacgc tcctgcctac ccagttccac tggggcaagc tcctcggaca ccaagcagaa
3061 ttctgcatgg tgacagtctc ccccaaacat ggcctgctgg gcccaagtga ggagtgccag
3121 ctcaagttgg agttgactgc tcatacccag gaagagctga cccatctggc cctcccttgt
3181 cacgtgtcag gcatgaagaa gccactggtt ctaggcattt ctgggaagcc ccagggactg
3241 caagtggcca ttaccatctc taaggagagc tctgattgca gcacagagca gtggccaggc
3301 cacccaaagg agctccgcct ggactttggc tcagcggtgc cactgaggac ccgtgtgact
3361 cgccagctca ttctcaccaa tcgctcccca atacggaccc gtttctccct caagtttgag
3421 tatttcggga gcccccaaaa cagcctgagc aaaaagacca gccttcccaa catgcctcct
3481 gccctgctaa agacagtgcg gatgcaagag cacctggcca agcgagagca gctggatttt
3541 atggagagca tgctatccca cgggaaagga gctgctttct tccctcactt ttcccagggc
3601 atgctggggc cctaccagca gctgtgcatt gacatcacag gctgtgccaa catgtggggc
3661 gagtactggg acaacctcat ctgcacggtg ggagacctgc tgccggaagt catcccagtg
3721 cacatggcag cggtgggctg ccccatcagc tccctgagga ccacctccta cactattgac
3781 caggcccaga aggaaccagc catgaggttc ggcacccagg tctccggagg agacacagtt
3841 acccgaaccc ttcgcctgaa taactccagc ccctgtgaca tccgcctgga ttgggagacc
3901 tatgttccag aagacaagga agaccggctg gtggagctgc tggtgtttta tgggccacct
3961 ttcccgctgc gggaccaagc cgggaatgag cttgtgtgcc ctgatacccc tgagggtggc
4021 tgcctcctct ggtccccagg cccctccagt tcatcggaat tcagccatga aactgactca
4081 tcagttgagg gcagctccag tgccagcaat agggtggcac agaagctcat ctcagtcatc
4141 ctgcaggcac atgagggggt gccctccggc cacctgtact gtatcagccc caagcaggtg
4201 gtggtccctg ctgggggcag cagtaccatc tacatctcct tcacccctat ggtgctcagc
4261 cctgagatcc tgcacaaggt ggagtgtact ggctacgccc tgggtttcat gagcttggac
4321 agcaaggtgg aaagggagat tccacggaag aggcatcgcc tgcaggactt tgcggtggga
4381 cccctgaaac tggacctgca tagctacgtg aggcctgcac agctaagtgt ggagctggac
4441 tacggcggca gtatggaatt ccagtgccag gccagtgacc tcattcccga gcagccctgc
4501 tctggggtgc tgagtgagct ggtgaccacc caccacctga agctgaccaa cactacagag
4561 atcccacact acttccggct tatggtctcc aggcccttct ccgtttctca agatggggcg
4621 agccaggacc acagagctcc tggccctggc cagaagcagg agtgtgagga ggagacagcc
4681 tcagcggaca agcagctggt gctccaagca caggagaaca tgctggtgaa cgtgtccttc
4741 tcactctccc tggagctgct ctcctatcag aagctcccag ctgaccagac actgcctggg
4801 gtggacattc agcagagtgc gagtggagag agagagatgg tgtttactca gaacctgctc
4861 ctggagtaca ccaaccagac cactcaggtg gtgcccctgc gggctgtggt ggccgtgcct
4921 gagctgcagc tctccaccag ctgggtggac tttgggacct gctttgtgag ccagcagcga
4981 gtccgggagg tctacctgat gaacctgagc gggtgccgaa gctactggac tatgctgatg
5041 ggccagcagg agccagccaa ggccgctgtg gccttcaggg tctccccaaa cagtgggctg
5101 ctagaagcac gatccgccaa tgcaccccca acctccatcg cgttgcaggt tttcttcact
5161 gccaggagta gtgagctgta cgagtccacg atggtggtgg aaggtgtgct cggtgagaag
5221 tcctgcaccc tgcggctccg gggccaaggc tcctatgatg agagatacat gttgcctcac
5281 cagccctgag gctccgcccc agccctcagc cccaggcccc agctggagaa aaaacattgc
5341 ccagggatta ggagcagctc ttcagcacaa agacacagac ttggggacct ggggacctct
5401 gggcagctcc tggaatggaa gaaccccctt ccacaatggt ctcagcctag gccctcatga
5461 tttgtcctca gagctaacat aaaggacagg ccacaccaca gcagagacca ccacattgag
5521 atcactactc agtgcatagc gaagaccagt atggcaaaat tagtcttgga aaaaaaccac
5581 agccactaag ataaattcat gcacttttac tatgc
//