LOCUS AB015718 4221 bp mRNA linear HUM 07-JAN-1999
DEFINITION Homo sapiens lok mRNA for protein kinase, complete cds.
ACCESSION AB015718
VERSION AB015718.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4221)
AUTHORS Kuramochi,S. and Karasuyama,H.
TITLE Direct Submission
JOURNAL Submitted (22-JUN-1998) to the DDBJ/EMBL/GenBank databases.
Contact:Satomi Kuramochi
The Tokyo Metropolitan Institute of Medical Science, Department of
Immunology; 18-22, Honkomagome 3-chome, Bunkyo-ku, Tokyo 113-8613,
Japan
REFERENCE 2
AUTHORS Kuramochi,S., Matsuda,Y., Okamoto,M., Kitamura,F., Yonekawa,H. and
Karasuyama,H.
TITLE Molecular cloning of the human gene STK10 encoding
lymphocyte-oriented kinase and comparative chromosomal mapping of
the huma, mouse, and rat homologues
JOURNAL Immunogenetics (1999) In press
COMMENT
FEATURES Location/Qualifiers
source 1..4221
/cell_line="NALM6"
/cell_type="preB cell"
/chromosome="5"
/db_xref="H-InvDB:HIT000058448"
/db_xref="taxon:9606"
/map="5q35.1"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 51..2957
/codon_start=1
/gene="lok"
/note="STE20-like Ser/The kinase"
/product="protein kinase"
/protein_id="BAA35073.1"
/transl_table=1
/translation="MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGD
GAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYH
DGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKA
GNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKA
DIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALD
KNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEEIEDGRDEGEEEDAVDAA
STLENHTQNSSEVSPPSLNADKPLEESPSTPLAPSQSQDSVNEPCSQPSGDRSLQTTS
PPVVAPGNENGLAVPVPLRKSRPVSMDARIQVAQEKQVAEQGGDLSPAANRSQKASQS
RPNSSALETLGGEKLANGSLEPPAQAAPGPSKRDSDCSSLCTSESMDYGTNLSTDLSL
NKEMGSLSIKDPKLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQEL
RELRLLQKEEHRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQV
EKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQ
KMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDRE
AALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVR
QQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKSERL
QQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLVEHETQKLKALDESHNQNLKEWR
DKLRPRKKALEEDLNQKKREQEMFFKLSEEAECPNPSTPSKAAKFFPYSSADAS"
regulatory 4197..4202
/regulatory_class="polyA_signal_sequence"
polyA_site 4221
/note="22 A nucleotides"
BASE COUNT 1027 a 1188 c 1252 g 754 t
ORIGIN
1 cagcccgagc ccgagcccga gcccgagccg gcgccaccgc gcccccggcc atggcttttg
61 ccaatttccg ccgcatcctg cgcctgtcta ccttcgagaa gagaaagtcc cgcgaatatg
121 agcacgtccg ccgcgacctg gaccccaacg aggtgtggga gatcgtgggc gagctgggcg
181 acggcgcctt cggcaaggtt tacaaggcca agaataagga gacgggtgct ttggctgcgg
241 ccaaagtcat tgaaaccaag agtgaggagg agctggagga ctacatcgtg gagattgaga
301 tcctggccac ctgcgaccac ccctacattg tgaagctcct gggagcctac tatcacgacg
361 ggaagctgtg gatcatgatt gagttctgtc cagggggagc cgtggacgcc atcatgctgg
421 agctggacag aggcctcacg gagccccaga tacaggtggt ttgccgccag atgctagaag
481 ccctcaactt cctgcacagc aagaggatca tccaccgaga tctgaaagct ggcaacgtgc
541 tgatgaccct cgagggagac atcaggctgg ctgactttgg tgtgtctgcc aagaatctga
601 agactctaca gaaacgagat tccttcatcg gcacgcctta ctggatggcc cccgaggtgg
661 tcatgtgtga gaccatgaaa gacacgccct acgactacaa agccgacatc tggtccctgg
721 gcatcacgct gattgagatg gcccagatcg agccgccaca ccacgagctc aaccccatgc
781 gggtcctgct aaagatcgcc aagtcagacc ctcccacgct gctcacgccc tccaagtggt
841 ctgtagagtt ccgtgacttc ctgaagatag ccctggataa gaacccagaa acccgaccca
901 gtgccgcgca gctgctggag catcccttcg tcagcagcat caccagtaac aaggctctgc
961 gggagctggt ggctgaggcc aaggccgagg tgatggaaga gatcgaagac ggccgggatg
1021 agggggaaga ggaggacgcc gtggatgccg cctccaccct ggagaaccat actcagaact
1081 cctctgaggt gagtccgcca agcctcaatg ctgacaagcc tctcgaggag tcaccttcca
1141 ccccgctggc acccagccag tctcaggaca gtgtgaatga gccctgcagc cagccctctg
1201 gggacagatc cctccaaacc accagtcccc cagtcgtggc ccctggaaat gagaacggcc
1261 tggcagtgcc tgtgcccctg cggaagtccc gacccgtgtc aatggatgcc agaattcagg
1321 tagcccagga gaagcaagtt gctgagcagg gtggggacct cagcccagca gccaacagat
1381 ctcaaaaggc cagccagagc cggcccaaca gcagcgccct ggagaccttg ggtggggaga
1441 agctggccaa tggcagcctg gagccacctg cccaggcagc tccagggcct tccaagaggg
1501 actcggactg cagcagcctc tgcacctctg agagcatgga ctatggtacc aatctctcca
1561 ctgacctgtc gctgaacaaa gagatgggct ctctgtccat caaggacccg aaactgtaca
1621 aaaaaaccct caagcggaca cgcaaatttg tggtggatgg tgtggaggtg agcatcacca
1681 cctccaagat catcagcgaa gatgagaaga aggatgagga gatgagattt ctcaggcgcc
1741 aggaactccg agagcttcgg ctgctccaga aagaagagca tcggaaccag acccagctga
1801 gtaacaagca tgagctgcag ctggagcaaa tgcataaacg ttttgaacag gaaatcaacg
1861 ccaagaagaa gttctttgac acggaattag agaacctgga gcgtcagcaa aagcagcaag
1921 tggagaagat ggagcaagac catgccgtgc gccgccggga ggaggccagg cggatccgcc
1981 tggagcagga tcgggactac accaggttcc aagagcagct caaactgatg aagaaagagg
2041 tgaagaacga ggtggagaag ctcccccgac agcagcggaa ggaaagcatg aagcagaaga
2101 tggaggagca cacgcagaaa aagcagcttc ttgaccggga ctttgtagcc aagcagaagg
2161 aggacctgga gctggccatg aagaggctca ccaccgacaa caggcgggag atctgtgaca
2221 aggagcgcga gtgcctcatg aagaagcagg agctccttcg agaccgggaa gcagccctgt
2281 gggagatgga agagcaccag ctgcaggaga ggcaccagct ggtgaagcag cagctcaaag
2341 accagtactt cctccagcgg cacgagctgc tgcgcaagca tgagaaggag cgggagcaga
2401 tgcagcgcta caaccagcgc atgatagagc agctgaaggt gcggcagcaa caggaaaagg
2461 cgcggctgcc caagatccag aggagtgagg gcaagacgcg catggccatg tacaagaaga
2521 gcctccacat caacggcggg ggcagcgcag ctgagcagcg tgagaagatc aagcagttct
2581 cccagcagga ggagaagagg cagaagtcgg agcggctgca gcaacagcag aaacacgaga
2641 accagatgcg ggacatgctg gcgcagtgtg agagcaacat gagcgagctg cagcagctgc
2701 agaatgaaaa gtgccacctc ctggtagagc acgaaaccca gaaactgaag gccctggatg
2761 agagccataa ccagaacctg aaggaatggc gggacaagct tcggccgcgc aagaaggctc
2821 tggaagagga tctgaaccag aagaagcggg agcaggagat gttcttcaag ctgagcgagg
2881 aggcggagtg cccaaacccc tccaccccaa gcaaggccgc caagttcttc ccctacagtt
2941 ctgcggatgc ttcttaacaa ccgcccgggg ctgtggctgg cagcttggtg ggccccaggg
3001 ccttctcctt cattctctgt gaacatgtaa ctcaggaccc cttttccctc ttgcgtctgt
3061 gccagctcaa atccagcccc tcgccctgtg ccaccccaac tgtgcctgat agacctgccc
3121 cagcgttcct gacttcttgc tggcctgtgg agggtgaggt gtaattattt gtcacctgaa
3181 cctaatgtat attctccttg agccccagat cccttcaagc tggaagggat ggggctgttg
3241 gtggggtcag ggtccaagag gaatgggtgt tctgtggcct cgagtcctct cctgtttgcg
3301 aaaataccag ttttgctctc tgtgggacaa agcactgctg atgaagtccc cgtgggctca
3361 tccgggctgg aattcttggt ttttcagcca ttccctgcag agtcactcaa tcatcaagtc
3421 cctcacagcc atttctgttc ccagaggagc caggcctgca gctggctgct caggagatgg
3481 cctcattcct cctgttctcc cagtttgctt tccacttaag acaaagcctt gtctatgtgg
3541 ggggcgggga ccggggaaag agggaggctg aaatgtttat tctgcttctc ccgtgtttca
3601 tgccatctcg cgtccccctt cctgcacatg ggtgtgaatg cacacacata cgcgtacaca
3661 caggacttgg tctgctggcc tggcctcttc tgcccaggtg ggttggaaca cgtttgctgc
3721 ctgagcctgt gccactgagc atgttaggtg gagcagttgg tgtggcacgt gcggggtgtt
3781 ggcaccggag gcatggaaaa gcacaggctg tactgccagg ctgcgatgcg tgctggcccc
3841 cgcacaggct cctgtgtgca gggactgatt cctcagcaca cgaggcttcc acaacccagt
3901 ctgctccata gcactctggc ccaccctgtc tgcaggtgaa acaggagggc tgtttgcctc
3961 tgccccatcc ccccgactgt gttcaggagt cccaccttgc atttcagacc tgggctggca
4021 gtctgttgga cttctcttca ggaagaaaaa gcatcagggg gaaatggaat gcccctgccc
4081 caggaacatg gcagaagcac aggttctgta cctcagatgg actcctgctg ggccttcggg
4141 gtctcagttg gcttccccca gattctgatt ctacagctgc agaatgtata taacacaata
4201 aaagcaaatg tttgaaccag t
//