LOCUS AB008430 3442 bp mRNA linear HUM 13-FEB-1999
DEFINITION Homo sapiens mRNA for CDEP, complete cds.
ACCESSION AB008430
VERSION AB008430.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3442)
AUTHORS Koyano,Y., Kawamoto,T. and Kato,Y.
TITLE Direct Submission
JOURNAL Submitted (22-OCT-1997) to the DDBJ/EMBL/GenBank databases.
Contact:Takeshi Kawamoto
Hiroshima University School of Dentistry, Department of
Biochemistry; 1-2-3 Kasumi Minami-ku, Hiroshima, Hiroshima 734,
Japan
REFERENCE 2
AUTHORS Koyano,Y., Kawamoto,T., Shen,M., Yan,W., Noshiro,M., Fujii,K. and
Kato,Y.
TITLE Molecular cloning and characterization of CDEP, a novel human
protein containing the ezrin-liks domain of the band 4.1
superfamily and the Dbl homology domain of rho guanine nucleotide
exchange factors
JOURNAL Biochem. Biophys. Res. Commun. 241, 369-375 (1997)
COMMENT
FEATURES Location/Qualifiers
source 1..3442
/cell_type="chondrocyte"
/db_xref="H-InvDB:HIT000058154"
/db_xref="taxon:9606"
/dev_stage="embryo"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="cartilage"
CDS 49..3186
/codon_start=1
/function="Rho Guanine Nucleotide Exchange Factor"
/note="Band 4.1 superfamily"
/product="CDEP"
/protein_id="BAA24267.1"
/transl_table=1
/translation="MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKI
QMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIV
KQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLI
SHIVQSEIGDFDEALDREHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEI
ARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRF
LIKLRPDANSAYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRG
SSFRFSGRTQKQVLDYVKEGGHKKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQS
TSLTFGEGAESPGGQSCRRGKEPKVSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEE
EEEVVKDRTQQSKPQPPQPSTGSLTGSPHLSELSVNSQGGVAPANVTLSPNLSPDTKQ
ASPLISPLLNDQACPRTDDEDEGRRKRFPTDKAYFIAKEVSTTERTYLKDLEVITSWF
QSTVSKEDAMPEALKSLIFPNFEPLHKFHTNFLKEIEQRLALWEGRSNAQIRDYQRIG
DVMLKNIQGMKHLAAHLWKHSEALEALENGIKSSRRLENFCRDFELQKVCYLPLNTFL
LRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAALAEITEMVAQLHGTMIKMENFQKL
HELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQ
FKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIVAASSRSEMEKWVEDIQMAID
LAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSASRTSLERQAPHRGNTMVHV
CWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSHQDNHP
LASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYTFERWMEVIRSATSS
ASRPHVLSHKESLVY"
polyA_site 3442
/note="50 a nucleotides"
BASE COUNT 864 a 952 c 927 g 699 t
ORIGIN
1 cgccgcagcc gccggcgctg tggagatatt ctctaagccg ctttcatcat gggagaaata
61 gagcagaggc cgaccccagg atcacgactg ggggccccgg aaaattcggg gatcagtacc
121 ttggaacgtg gacagaagcc gcccccaaca ccttcaggaa aactcgtgtc catcaaaatc
181 cagatgctgg atgacaccca ggaggcattt gaagttccac aaagagctcc tgggaaggtg
241 ctgctggatg cagtttgcaa ccacctcaac ctcgtggaag gtgactattt tggcctcgag
301 tttcctgatc acaaaaagat cacggtgtgg ctggatctcc taaaacccat tgtgaaacag
361 attagaaggc caaagcacgt tgttgttaag tttgtggtga aattctttcc gcctgaccac
421 acacaactcc aagaagaact cacaaggtac ctgttcgcgc tgcaggtgaa gcaggacttg
481 gctcaaggca ggttgacgtg taatgacacc agcgcagctc tcttgatttc acacattgtg
541 caatctgaga ttggggattt tgatgaagcc ttggacagag agcacttagc aaaaaataaa
601 tacatacctc agcaagacgc actagaggac aaaatcgtgg aatttcacca taaccacatt
661 ggacaaacac cagcagaatc agatttccag ctcctagaga ttgcccgtcg gctagagatg
721 tatggaatcc ggttgcaccc ggccaaggac agggaaggca cgaagatcaa tctggccgtt
781 gccaacacgg gaattctagt gtttcagggt ttcactaaga tcaatgcctt caactgggcc
841 aaggtgcgga agctgagctt caagaggaag cgctttctca tcaagctccg gccagatgcc
901 aatagtgcgt accaggatac cttggaattc ctgatggcca gtcgggattt ctgcaagtcc
961 ttctggaaaa tctgtgttga acatcatgcc ttctttagac tttttgaaga gcccaaacca
1021 aagcccaagc ccgtcctctt tagccggggg tcatcatttc ggttcagtgg tcggactcag
1081 aagcaggttc tcgactatgt taaagaagga ggacataaga aggtgcagtt tgaaaggaag
1141 cacagcaaga ttcattctat ccggagcctt gcttcacagc ctacagaact gaattcggaa
1201 gtgctggagc agtctcagca gagcaccagc cttacatttg gagaaggtgc cgaatctcca
1261 gggggccaga gctgccggcg aggaaaggaa ccgaaggttt ccgccgggga gccggggtcg
1321 cacccgagcc ctgcgccgag gagaagcccc gcgggtaaca agcaggcgga cggagccgcc
1381 tcggcgccca cggaggaaga ggaggaggtc gttaaggata ggacccagca gagtaaacct
1441 cagcccccgc agccaagcac aggctccctg actggcagtc ctcacctttc cgagctgtct
1501 gtgaactcgc aggggggagt ggcccctgcc aacgtgacct tgtctcccaa cctgagcccc
1561 gacaccaagc aggcctctcc cttgatcagc ccgctgctga atgaccaggc ctgcccccgg
1621 acggacgatg aggatgaggg ccggaggaag agattcccaa ctgataaagc gtacttcata
1681 gctaaggaag tgtctaccac cgagcgaaca tatctgaagg atctcgaagt tatcacttcg
1741 tggtttcaga gcacagtgag caaagaggac gccatgccgg aagcactgaa aagtctcata
1801 ttcccgaatt ttgaaccttt gcacaaattt catactaatt ttctcaagga aattgagcaa
1861 cgacttgccc tgtgggaagg ccgctcaaat gcccaaatca gagattacca aagaatcggc
1921 gatgtcatgc tgaagaacat tcagggcatg aagcacctgg cggctcacct gtggaagcac
1981 agcgaggcct tggaggccct ggagaatgga atcaagagct cccggcggct ggagaacttc
2041 tgcagagact ttgagctgca gaaggtgtgt tacctaccgc tcaacacctt cctcctgcgg
2101 ccactgcacc ggctcatgca ctacaagcag gtcctggagc ggctgtgcaa acaccacccg
2161 ccgagccacg ccgacttcag ggactgccga gccgctttgg cagagatcac ggagatggtg
2221 gcacagctcc acggtacgat gatcaagatg gagaatttcc agaagctgca cgaactcaag
2281 aaagatttga ttggcattga caatcttgtg gttccgggaa gggagttcat ccgtctgggc
2341 agcctcagca agctctcggg gaaggggctc cagcagcgca tgttcttcct gttcaacgac
2401 gtcctgctat acacgagccg ggggctgacg gcctccaatc agtttaaagt ccacgggcag
2461 ctcccgctct atggcatgac gattgaggag agcgaagacg agtggggggt gccccactgc
2521 ctgaccctcc ggggccagcg gcagtccatc atcgtggccg ccagttctcg gtccgagatg
2581 gagaagtggg ttgaggacat ccagatggcc attgacctgg cggagaagag cagcagcccc
2641 gcccctgagt tcctggccag cagcccccct gacaacaagt cccctgatga agccaccgcg
2701 gctgaccagg agtcagagga tgacctgagc gcctcgcgca catcgctgga gcgccaggcc
2761 ccgcaccgcg gcaacacaat ggtgcacgtg tgctggcacc gcaacaccag cgtctccatg
2821 gtggacttca gcatcgcagt ggagaatcag ttgtctggaa acctgctgag gaaattcaaa
2881 aacagcaacg ggtggcagaa gctgtgggtg gtgttcacaa acttctgcct gttcttctac
2941 aaatcacacc aggacaatca tccccttgcc agcctgcctc tgctcggcta ctcgctcacc
3001 atcccctctg agtccgagaa catccagaaa gactacgtgt tcaagctgca cttcaagtcc
3061 cacgtctact acttcagggc ggaaagcgag tacacgttcg aaaggtggat ggaagtgatc
3121 cgcagtgcca ccagctctgc ctcgcgaccc cacgtgttga gccacaaaga gtctcttgtg
3181 tattgatggc cggacacact cgtttccgca gtggctgctt tcctggaaga cgtttccttt
3241 cttctgtatt aatgaagcct ggtaaaatta acacctgtct gaaaatcaaa aacatggctt
3301 cccagcagct ctcctgtctc cacagccgcg ttttttaacc ccgacctctc agcgtttgaa
3361 tgaacagcgc tcccacctcc agtcctggca tccgctgggg gcgctgttct ttagctagtg
3421 ccagtattaa aacattgtca tt
//