LOCUS AB005047 2570 bp mRNA linear HUM 11-JUN-1998
DEFINITION Homo sapiens Sab mRNA for SH3 binding protein, complete cds.
ACCESSION AB005047
VERSION AB005047.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2570)
AUTHORS Matsushita,M.
TITLE Direct Submission
JOURNAL Submitted (23-JUN-1997) to the DDBJ/EMBL/GenBank databases.
Contact:Masato Matsushita
Osaka University Medical School, Department of Medicine 3;
2-2,Yamada-oka, Suita City, Osaka 565, Japan
REFERENCE 2
AUTHORS Matsushita,M., Yamadori,T., Kato,S., Takemoto,Y., Inazawa,J.,
Baba,Y., Hashimoto,S., Sekine,S., Arai,S., Kunikata,T.,
Kurimoto,M., Kishimoto,T. and Tsukada,S.
TITLE Identification and characterization of a novel SH3-domain binding
protein, Sab, which preferentially associates with Bruton's
tyrosine kinase (Btk)
JOURNAL Biochem. Biophys. Res. Commun. 245, 337-343 (1998)
COMMENT
FEATURES Location/Qualifiers
source 1..2570
/chromosome="1"
/db_xref="H-InvDB:HIT000058045"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 64..1341
/codon_start=1
/gene="Sab"
/note="This protein preferentially associates with
activated form of Btk(Sab)."
/product="SH3 binding protein"
/protein_id="BAA25922.1"
/transl_table=1
/translation="MEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFR
SVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAA
KETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAA
MGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALK
NLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDLPGSKPEPDAISVASEAFEDDS
CSNFVSEDDSETQSVSSFSSGPTSPSEMPDQFPAVVRPGSLDLPSPVSLSEFGMMFPV
LGPRSECSGASSPECEVERGDRAEGAENKTSDKANNNRGLSSSSGSGGSSKSQSSTSP
EGQALENRMKQLSLQCSKGRDGIIADIKMVQIG"
polyA_site 2570
/note="104 A nucleotides"
BASE COUNT 724 a 529 c 720 g 597 t
ORIGIN
1 tcggaggagc cagccgaaat cctgccgcct gcccgggacg aggaggagga ggaggaagag
61 gggatggagc aggggctgga ggaggaagaa gaggtggatc cccggatcca gggagaactg
121 gagaagttaa atcagtccac ggatgatatc aacagacggg agactgaact tgaggatgct
181 cgtcagaagt tccgctctgt tctggttgaa gcaacggtga aactggatga actggtgaag
241 aaaattggca aagctgtgga agactccaag ccctactggg aggcacggag ggtggcgagg
301 caggctcagc tggaagctca gaaagccacg caggacttcc agagggccac agaggtgctc
361 cgtgccgcca aggagaccat ctccctggcc gagcagcggc tgctggagga tgacaagcgg
421 cagttcgact ccgcctggca ggagatgctg aatcacgcca ctcagagggt catggaggcg
481 gagcagacca agaccaggag cgagctggtg cataaggaga cggcagccag gtacaatgcc
541 gccatgggcc gcatgcgaca gctggagaag aaactcaaga gagccatcaa caagtccaag
601 ccttattttg aactcaaggc aaagtactat gtgcagctcg agcaactgaa aaagactgtg
661 gatgacctgc aggccaaact gaccctggca aaaggcgagt acaagatggc cctgaagaac
721 ctggagatga tctcagatga gatccacgag cggcggcgct ccagtgccat ggggcctcgg
781 ggatgcggtg ttggtgctga gggcagcagc acatctgtgg aggatctgcc agggagcaaa
841 cctgagcctg atgccatttc tgtggcctcg gaggcctttg aagatgacag ctgtagcaac
901 tttgtgtctg aagatgactc ggaaacccag tccgtgtcca gctttagttc aggaccaaca
961 agcccgtctg agatgcctga ccagttccct gcggttgtga ggcctggcag cctggatctg
1021 cccagccctg tgtccctgtc agagtttggg atgatgttcc cagtgttggg ccctcgaagt
1081 gaatgcagcg gggcctcctc ccctgaatgt gaagtagaac gaggagacag ggcagaaggg
1141 gcagagaata aaacaagtga caaagccaac aacaaccggg gcctcagcag tagcagtggc
1201 agtggtggca gcagtaagag ccaaagcagc acctcccctg agggccaggc cttggagaac
1261 cggatgaagc agctctccct acagtgctca aagggaagag atggaattat tgctgacata
1321 aaaatggtgc agattggctg attcatcctg ggccctggcc gatgtgcata tcaacattta
1381 tacatggaac tggagaacat tgtgccaata atcatttaat atatgccaaa tcttacacgt
1441 ctactctaaa ctgctctaat gaagtttcag tgaccttgag ggctaaagat tgttcttctg
1501 ggtaagagct cttgggctgg tttttcagag cagagttctt gttgtgggta gactgtgact
1561 aggttcacag cctttgtgga acattccgta taacggcatt gtggaagcaa taactagttc
1621 ctatgaaaga accagagctg ggaagatggc tgggaagcca ggccaaagtg ggggcaacag
1681 cttgcttctc tttctcttct caccctcagt ttgtatggga aaatggagat gtcctctcca
1741 ctttatccca cgatatctaa atgaaaaaga aagaaaaccc acacacaaag caaaaactca
1801 agtattaaga gcacatattt ttgacccagt ggaggcttaa aaaaaaaaaa atccaagaac
1861 acaattcatt ttcaccacct ctggtgttca gagggggctt ttaaaaaagc gtgtatgctg
1921 ggatacccat taaaaccatt ttctagaagg ctaccatgag ctgcactttt tggggtggga
1981 aaggtgaatg ccagtgggga tgcgggggga tgagggtagg agggacttat agaaggggat
2041 ttgtggctgt gggggagaag gttctacagc ataagcctta tcctgccagc caaggggatt
2101 tattctaaga gaagtgcatg tgaagaatgg ttgccactgt tattagattg acaagatgtt
2161 aatttctctg taggttgtaa ctttaaaaat aaatgaaatt atttaagggt tatgctgcac
2221 tagtattcct tagaggaaac agttctttaa agttaggaaa gggagtaggc aggcatgtgt
2281 tggcaaaggc tgttaatagt agttaagtgt taagactgct tttctttaac gttttcatgg
2341 taatgcatat ttagagcact gtatttttgt cttgttaaga aaatttagca tttctaaaag
2401 aaaaaagcaa ccctctttca aactgttaat tctgtcacag cctgtatatt ttagtcattt
2461 gtaaatctct tcatacaata gtgacttctt ttttgactga tacagtatct taattacaag
2521 gttattttgt acttgtctta atacactaag tgtaataaaa acggcttgag
//