LOCUS AB002804 5810 bp mRNA linear HUM 29-APR-2000
DEFINITION Homo sapiens mRNA for hSLK, complete cds.
ACCESSION AB002804
VERSION AB002804.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5810)
AUTHORS Yamada,E.
TITLE Direct Submission
JOURNAL Submitted (08-APR-1997) to the DDBJ/EMBL/GenBank databases.
Contact:Eitaro Yamada
Faculty of Pharmaceutical Sciences, Osaka University, Immunology;
Yamadaoka 1-6, Suita, Osaka 565, Japan
REFERENCE 2
AUTHORS Yamada,E., Tsujikawa,K., Itoh,S., Kameda,Y., Kohama,Y. and
Yamamoto,H.
TITLE Molecular cloning and characterization of a novel human STE20-like
kinase, hSLK
JOURNAL Biochim. Biophys. Acta 1495, 250-262 (2000)
COMMENT
FEATURES Location/Qualifiers
source 1..5810
/cell_line="A549"
/db_xref="H-InvDB:HIT000058003"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 233..3847
/codon_start=1
/function="serine/threonine kinase"
/product="hSLK"
/protein_id="BAA19655.1"
/transl_table=1
/translation="MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGA
FGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYEN
NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGN
ILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADV
WSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKN
VDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIP
ASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEK
AVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEG
KENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETGE
KEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSA
EDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSS
ENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKE
KKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEIGSLSKTETILPPES
ENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETRRQKKTLKKTRKF
IVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNSKLQQQR
EQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKE
LSKFQNMLKNRKKEEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRA
REAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELK
NRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNE
RMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKE
WREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS
"
polyA_site 5810
/note="25 A nucleotides"
BASE COUNT 2035 a 958 c 1239 g 1578 t
ORIGIN
1 tttaagcata ttagtcagcg gaggagaaga aactaaccag gattccctca gtaacggcga
61 gtgaacaggg aagagcccag cgccgaatcc ccgccccgcg cggcgagctg cgggggccga
121 gggacgccgc gcccgccgcc gccagccggc tcgcgctgga gcagggacag agaaactttg
181 ccttttattg tttttagtcc ttaagtgcaa ggactctgtg ttgggaggaa aaatgtcctt
241 cttcaatttc cgtaagatct tcaagttggg gagcgagaag aagaagaagc agtacgaaca
301 cgtgaagagg gacctgaacc ccgaagactt ttgggagatt ataggagaac tgggcgacgg
361 agcctttggg aaagtgtaca aggcccagaa taaagagacc agtgttttag ctgctgcaaa
421 agtgattgac actaaatctg aagaagaact tgaagattac atggtagaga ttgacatatt
481 agcatcttgt gatcacccaa atatagtcaa gcttctagat gccttctatt atgagaacaa
541 tctttggatc ctcattgaat tttgtgcagg tggagcagta gatgctgtga tgcttgaact
601 tgagagacca ttaactgagt cccaaataca agtagtttgc aagcagactt tagatgcatt
661 gaactactta catgataata agatcatcca cagagatctg aaggctggca acattctctt
721 taccttagat ggagatatca aattggcgga ttttggagta tcagctaaaa acacgaggac
781 aattcaaaga agagattcct ttattggtac accatattgg atggctcctg aagtagtcat
841 gtgtgaaaca tctaaggaca gaccctatga ctacaaagct gatgtttggt ccctgggtat
901 cactttaata gaaatggctg agatagaacc acctcatcat gaattaaatc caatgcgagt
961 gctgctaaaa atagcaaaat ctgagccacc tacattagca cagccatcca gatggtcttc
1021 aaattttaag gactttctaa agaaatgctt agaaaagaat gtggatgcca ggtggactac
1081 atctcagctg ctgcagcatc cctttgttac tgttgattcc aacaaaccca tccgagaatt
1141 gattgcagag gcgaaggctg aagtaacaga agaagttgaa gatggcaaag aggaagatga
1201 agaggaggaa acagaaaatt ctctgccaat acctgcaagt aagcgtgcat cttctgacct
1261 tagtatcgcc agctctgaag aagataaact ttcacaaaat gcttgtattt tggagtctgt
1321 ctcagaaaaa acagaacgta gtaactctga agataaactc aacagcaaaa ttcttaatga
1381 aaaacccacc actgatgaac ctgaaaaggc tgtggaggat attaatgaac atattaccga
1441 tgctcagtta gaagcaatga ctgaactcca tgacagaaca gcagtaatca aggagaatga
1501 aagagagaag aggcccaagc ttgaaaatct gcctgacaca gaagaccaag aaactgtgga
1561 cattaattca gtcagtgaag gaaaagagaa taatataatg ataaccttag aaacaaatat
1621 tgaacataat ctaaaatctg aggaagaaaa ggatcaggaa aagcaacaga tgtttgaaaa
1681 taagcttata aaatctgaag aaattaaaga tactattttg caaacagtag atttagtttc
1741 tcaagagact ggagaaaaag aggcaaatat tcaggcagtt gatagtgaag ttgggcttac
1801 aaaggaagac acccaagaga aattggggga agacgacaaa actcaaaaag atgtgattag
1861 caatacaagt gatgtgatag gaacatgtga ggcagcagat gtggctcaga aagtggatga
1921 agacagtgct gaggatacgc agagtaatga tgggaaagaa gtggtcgaag taggccagaa
1981 attaattaat aagcccatgg tgggtcctga ggctggtggt actaaggaag ttcctattaa
2041 agaaatagtt gaaatgaatg aaatagaaga aggtaaaaat aaggaacaag caataaacag
2101 ttcagagaac ataatggaca tcaatgagga accaggaaca actgaaggtg aagaaatcac
2161 tgagtcaagt agcactgaag aaatggaggt cagaagtgtg gtggctgata ctgaccaaaa
2221 ggctttagga agtgaagttc aggatgcttc taaagtcact actcagatag ataaagagaa
2281 aaaagaaatt ccagtgtcaa ttaaaaaaga gcctgaagtt actgtagttt cacagcccac
2341 tgaacctcag cctgttctaa tacccagtat taatatcaac tctgacagtg gagaaaataa
2401 agaagaaata ggttctttat caaaaactga aactattctg ccaccagaat ctgagaatcc
2461 aaaggaaaat gataatgatt caggcactgg ttccactgct gatactagca gtattgactt
2521 gaatttatcc atctctagct ttctaagtaa aactaaagac agtggatcga tatctttaca
2581 agaaacaaga agacaaaaga aaacattgaa gaaaacacgc aaatttattg ttgatggtgt
2641 agaagtgagt gtaacaacat caaagatagt tacagatagt gattccaaaa ctgaagaatt
2701 gcggtttctt agacgtcagg aacttcggga attaagattt cttcagaaag aagagcaaag
2761 agcccaacaa cagctcaata gcaaactaca gcaacaacga gaacaaattt tccggcgctt
2821 tgagcaggaa atgatgagta aaaagcgaca atatgaccag gaaattgaga atctagaaaa
2881 acagcagaaa cagactatcg aacgcctgga acaagagcac acaaatcgct tgcgagatga
2941 agccaaacgc atcaaaggag aacaagagaa agagttgtcc aaatttcaga atatgctgaa
3001 gaaccgaaag aaggaggaac aagagtttgt tcagaaacaa cagcaagaat tagatggctc
3061 tctgaaaaag atcatccagc agcagaaggc agagttagct aatattgaga gagagtgcct
3121 gaataacaag caacagctca tgagagctcg agaagctgca atttgggagc tcgaagaacg
3181 acacttacaa gaaaaacacc agctgctcaa acagcagctt aaagatcagt atttcatgca
3241 aagacatcag ctacttaagc gccacgagaa ggaaacagag caaatgcagc gttacaatca
3301 aagacttatt gaggaattga aaaacagaca gactcaagaa agagcaagac tgcccaagat
3361 tcagcgcagt gaagccaaga ctcgaatggc catgtttaag aagagtttga gaattaactc
3421 aacagccaca ccagatcagg accgtgataa aattaaacag tttgctgcac aagaagaaaa
3481 gaggcagaaa aatgagagaa tggctcagca tcagaaacat gagaatcaaa tgcgagatct
3541 tcagttgcag tgtgaagcca atgtccgcga actgcatcag ctgcagaatg aaaaatgcca
3601 cttgttggtt gagcatgaga ctcagaaact gaaggagtta gatgaggaac atagccaaga
3661 attaaaggag tggagagaga aattgagacc taggaaaaag acactggaag aagagtttgc
3721 caggaaacta caggaacagg aagtattctt taaaatgact ggggagtctg aatgccttaa
3781 cccatcaaca cagagccgga tttccaaatt ttatcctatt cccagcttgc attccaccgg
3841 atcataacaa agggaagcat tctgtgcgtg ggtttggctc tttcagtatg tcattctgtt
3901 ctcatcttct gccacagtct ctcagatagc tcatgaagac aatcacctgc ctcaccttct
3961 aggtgttttc cttttttgtt ttttttgttt tgttttgttt ttaagccaaa gatgaaggga
4021 aaacgaacta agacagacgt taggccatgt tggcaaagta gcatcttggt gactaaggtg
4081 actttgtata ttcatcttaa aaattatgtt ctttagacac tgctacctga aaactgttgg
4141 agaaataatg tttaaagtta tttaagaaaa actgttacat cactaagtat taataaattc
4201 ttcttacctg acgtaacttc tcaatgccta aattctgtag ttgaagctct gctgcagaga
4261 gttgggataa ttttcttttg gtggatcagc tctcataaaa aagctatgat ttgctcaaat
4321 atgctgattg actcagtaaa tgaatatatt tttttcttta aataggaaca acctctttta
4381 aaagagaaaa attatttcag tgatttgtca aaacgaatta cctcttttgc atgagctaat
4441 aattgagggt gctaattttc ttaagatagt gcctaaaaca ctaaatttca gtcaagtcgt
4501 aagtaggatt ttctttttga tcaacaggga caaaaactat ctttagaatt aaaaacatgg
4561 ttgttttgga atttttgctt ctcttacgtt tgatagcaat tttcatccta aaatacatgt
4621 acaaagtttg gaaagatgaa aaaaagaggt agcttttaga ttgcaaattg gaaatgttaa
4681 aactcatgaa atttaagcaa tataggttta gctatctgtg tttattttct aaaataatac
4741 ctgagctggt taaatgattt ctctccatct tagctaattc tgtttaaaac tctgtcagag
4801 gcctgcaggc tgtgagttat atttataaat atatcttcag aaattaatct taaaagaggc
4861 attagttcag aatacttttt taaaagttta aattaaatat ttaggcacgt cagaaattac
4921 ttttccttat tttgaaatga ggctacttat gtcttggttt tattttgttc catgtttaaa
4981 tcattcactt tgatttgagt gggaaaagcc tgaagccttt atcatgtggt tgctggtgtg
5041 tgtaattatt aatgaaatgt tcactcctag tcccttatga ggcttagaat ttcaaccacg
5101 tgtcaggtca gacagtatta taaagtgtac tttgtgtctg agacagcaca tttgtgaatg
5161 atgcttgctg cctgccattt tcaacctatt ctctcttaag agtgctaggt accaaattgt
5221 gaaagtttgt ttgttttcag ttatattact tttgaggctg gtggaaaaat ttaaatgtaa
5281 ctttgtggga acactgattc atatttagaa aatgtaaatg tctgtagcac tttcttgcag
5341 ttaatttgaa aactttggat gctgaacctt gtttgtcagt gatttagatg atttaaaaat
5401 gcatgtgtga tttgaatttt ataattgttt tgacaagcat aatttacttg gacaacttcg
5461 taggtagcct taacttctgg ccaagtttgt tttttatata aatatatata catatataca
5521 tattatgtat ggttgtaaat tcatacactt atcacatgaa tgtgttactg tatacaaaac
5581 tcttaatgct ttattctcaa atgctgggtt gaaaaatgtt ttgaaagcct tttaaaatat
5641 atatctttat aaagtaatat tcaggatgat gataaaaatt gtttatattg ttatgataaa
5701 aatgacagta taatgttgcc cagtgtattt aatgatttat ttgaagaggg attgggaagg
5761 aacgtcttca taccactttc tcctttgaaa ttttcagttt attgactttt
//