LOCUS AB001535 6220 bp mRNA linear HUM 28-NOV-1998
DEFINITION Homo sapiens KNP3 mRNA, complete cds.
ACCESSION AB001535
VERSION AB001535.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6220)
AUTHORS Shimizu,N.
TITLE Direct Submission
JOURNAL Submitted (28-FEB-1997) to the DDBJ/EMBL/GenBank databases.
Contact:Nobuyoshi Shimizu
Keio University School of Medicine, Department of Molecular
Biology; 35 Shinanomachi, Shinjuku-ku, Tokyo 160, Japan
REFERENCE 2
AUTHORS Nagamine,K., Kudoh,J., Minoshima,S., Kawasaki,K., Asakawa,S.,
Ito,F. and Shimizu,N.
TITLE Molecular cloning of a novel putative Ca2+ channel protein (TRPC7)
highly expressed in brain
JOURNAL Genomics 54, 124-131 (1998)
COMMENT
FEATURES Location/Qualifiers
source 1..6220
/chromosome="21"
/db_xref="H-InvDB:HIT000057951"
/db_xref="taxon:9606"
/dev_stage="20-26weeks fetus"
/map="21q22.3"
/mol_type="mRNA"
/note="7 Caucasians"
/organism="Homo sapiens"
/tissue_lib="human fetal brain 5'-STRECH Plus cDNA
library (CLONTECH) and Human Brain, caudate nucleus
5'-STRECH cDNA library (CLONTECH)"
/tissue_type="brain"
CDS 446..4957
/codon_start=1
/gene="KNP3"
/note="similar to C.elegans hypothetical protein
CET01H8.1,CEC05C12.3,CEF54D1.5. similar to trp and
trp-like proteins"
/protein_id="BAA34700.1"
/translation="MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSW
RLQCPFGNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEA
TKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQ
HWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQV
GEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTC
LDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGP
GTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFE
TFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHE
NWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGV
QLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLR
ELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVTFTMDPIRD
LLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEY
EHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLT
KVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVV
FHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGL
MKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILSLDFILFCLRLMHIF
TISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVY
HSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLC
LYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLS
HLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQ
KIEDISNKVDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTARALHWIVRTLRASGFS
SEADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNEKV
PWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQ
AGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVK
LPLSEHWALPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTD
NAWIETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQK
AAAEFGAHY"
BASE COUNT 1248 a 1938 c 1882 g 1152 t
ORIGIN
1 tgtgcagaat tgtacagttg cgaaaccatg tcgctggcag ctggtgctgg cggtggagac
61 ttccctgtgc ggtgctcagt gcatctgcac ccgtggggga gggagctctt tctctggccc
121 tgcagtcacc tgaggttgtt accattatga acggccgctg ggacccccgc atgtgcatgt
181 actcccccag agtgtccggg ggccccagcc aagggacaca tctcacgcag ctgggaacat
241 gtgcaggctg atgaagagaa ccggatgagg gcttcacatg aggaagcatg tggccaggtc
301 ctctcagaac atcagcctca tcttcctgtc tctgatctat ttcaccaacc accccatgtg
361 tctctagaac cccagtgtag cgagctggag agaggactgt cctgagggca gcaggcctgg
421 ttgcagctgg cgtgggggtc tcagaatgga gccctcagcc ctgaggaaag ctggctcgga
481 gcaggaggag ggctttgagg ggctgcccag aagggtcact gacctgggga tggtctccaa
541 tctccggcgc agcaacagca gcctcttcaa gagctggagg ctacagtgcc ccttcggcaa
601 caatgacaag caagaaagcc tcagttcgtg gattcctgaa aacatcaaga agaaagaatg
661 cgtgtatttt gtggaaagtt ccaaactgtc tgatgctggg aaggtggtgt gtcagtgtgg
721 ctacacgcat gagcagcact tggaggaggc taccaagccc cacaccttcc agggcacaca
781 gtgggaccca aagaaacatg tccaggagat gccaaccgat gcctttggcg acatcgtctt
841 cacgggcctg agccagaagg tgaaaaagta cgtccgagtc tcccaggaca cgccctccag
901 cgtgatctac cacctcatga cccagcactg ggggctggac gtccccaatc tcttgatctc
961 ggtgaccggg ggggccaaga acttcaacat gaagccgcgg ctgaagagca ttttccgcag
1021 aggcctggtc aaggtggctc agaccacagg ggcctggatc atcacagggg ggtcccacac
1081 cggcgtcatg aagcaggtag gcgaggcggt gcgggacttc agcctgagca gcagctacaa
1141 ggaaggcgag ctcatcacca tcggagtcgc cacctggggc actgtccacc gccgcgaggg
1201 cctgatccat cccacgggca gcttccccgc cgagtacata ctggatgagg atggccaagg
1261 gaacctgacc tgcctagaca gcaaccactc tcacttcatc ctcgtggacg acgggaccca
1321 cggccagtac ggggtggaga ttcctctgag gaccaggctg gagaagttca tatcggagca
1381 gaccaaggaa agaggaggtg tggccatcaa gatccccatc gtgtgcgtgg tgctggaggg
1441 cggcccgggc acgttgcaca ccatcgacaa cgccaccacc aacggcaccc cctgtgtggt
1501 tgtggagggc tcgggccgcg tggccgacgt cattgcccag gtggccaacc tgcctgtctc
1561 ggacatcact atctccctga tccagcagaa actgagcgtg ttcttccagg agatgtttga
1621 gaccttcacg gaaagcagga ttgtcgagtg gaccaaaaag atccaagata ttgtccggag
1681 gcggcagctg ctgactgtct tccgggaagg caaggatggt cagcaggacg tggatgtggc
1741 catcttgcag gccttgctga aagcctcacg gagccaagac cactttggcc acgagaactg
1801 ggaccaccag ctgaaactgg cagtggcatg gaatcgcgtg gacattgccc gcagtgagat
1861 cttcatggat gagtggcagt ggaagccttc agatctgcac cccacgatga cagctgcact
1921 catctccaac aagcctgagt ttgtgaagct cttcctggaa aacggggtgc agctgaagga
1981 gtttgtcacc tgggacacct tgctctacct gtacgagaac ctggacccct cctgcctgtt
2041 ccacagcaag ctgcaaaagg tgctggtgga ggatcccgag cgcccggctt gcgcgcccgc
2101 ggcgccccgc ctgcagatgc accacgtggc ccaggtgctg cgggagctgc tgggggactt
2161 cacgcagccg ctttatcccc ggccccggca caacgaccgg ctgcggctcc tgctgcccgt
2221 tccccacgtc aagctcaacg tgcagggagt gagcctccgg tccctctaca agcgttcctc
2281 aggccatgtg accttcacca tggaccccat ccgtgacctt ctcatttggg ccattgtcca
2341 gaaccgtcgg gagctggcag gaatcatctg ggctcagagc caggactgca tcgcagcggc
2401 cttggcctgc agcaagatcc tgaaggaact gtccaaggag gaggaggaca cggacagctc
2461 ggaggagatg ctggcgctgg cggaggagta tgagcacaga gccatcgggg tcttcaccga
2521 gtgctaccgg aaggacgaag agagagccca gaaactgctc acccgcgtgt ccgaggcctg
2581 ggggaagacc acctgcctgc agctcgccct ggaggccaag gacatgaagt ttgtgtctca
2641 cgggggcatc caggccttcc tgaccaaggt gtggtggggc cagctctccg tggacaatgg
2701 gctgtggcgt gtgaccctgt gcatgctggc cttcccgctg ctcctcaccg gcctcatctc
2761 cttcagggag aagaggctgc aggatgtggg cacccccgcg gcccgcgccc gtgccttctt
2821 caccgcaccc gtggtggtct tccacctgaa catcctctcc tacttcgcct tcctctgcct
2881 gttcgcctac gtgctcatgg tggacttcca gcctgtgccc tcctggtgcg agtgtgccat
2941 ctacctctgg ctcttctcct tggtgtgcga ggagatgcgg cagctcttct atgaccctga
3001 cgagtgcggg ctgatgaaga aggcagcctt gtacttcagt gacttctgga ataagctgga
3061 cgtcggcgca atcttgctct tcgtggcagg gctgacctgc aggctcatcc cggcgacgct
3121 gtaccccggg cgcgtcatcc tctctctgga cttcatcctg ttctgcctcc ggctcatgca
3181 catttttacc atcagtaaga cgctggggcc caagatcatc attgtgaagc ggatgatgaa
3241 ggacgtcttc ttcttcctct tcctgctggc tgtgtgggtg gtgtccttcg gggtggccaa
3301 gcaggccatc ctcatccaca acgagcgccg ggtggactgg ctgttccgag gggccgtcta
3361 ccactcctac ctcaccatct tcgggcagat cccgggctac atcgacggtg tgaacttcaa
3421 cccggagcac tgcagcccca atggcaccga cccctacaag cctaagtgcc ccgagagcga
3481 cgcgacgcag cagaggccgg ccttccctga gtggctgacg gtcctcctac tctgcctcta
3541 cctgctcttc accaacatcc tgctgctcaa cctcctcatc gccatgttca actacacctt
3601 ccagcaggtg caggagcaca cggaccagat ttggaagttc cagcgccatg acctgatcga
3661 ggagtaccac ggccgccccg ccgcgccgcc ccccttcatc ctcctcagcc acctgcagct
3721 cttcatcaag agggtggtcc tgaagactcc ggccaagagg cacaagcagc tcaagaacaa
3781 gctggagaag aacgaggagg cggccctgct atcctgggag atctacctga aggagaacta
3841 cctccagaac cgacagttcc agcaaaagca gcggcccgag cagaagatcg aggacatcag
3901 caataaggtt gacgccatgg tggacctgct ggacctggac ccactgaaga ggtcgggctc
3961 catggagcag aggttggcct ccctggagga gcaggtggcc cagacagccc gagccctgca
4021 ctggatcgtg aggacgctgc gggccagcgg cttcagctcg gaggcggacg tccccactct
4081 ggcctcccag aaggccgcgg aggagccgga tgctgagccg ggaggcagga agaagacgga
4141 ggagccgggc gacagctacc acgtgaatgc ccggcacctc ctctacccca actgccctgt
4201 cacgcgcttc cccgtgccca acgagaaggt gccctgggag acggagttcc tgatctatga
4261 cccacccttt tacacggcag agaggaagga cgcggccgcc atggacccca tgggagacac
4321 cctggagcca ctgtccacga tccagtacaa cgtggtggat ggcctgaggg accgccggag
4381 cttccacggg ccgtacacag tgcaggccgg gttgcccctg aaccccatgg gccgcacagg
4441 actgcgtggg cgcgggagcc tcagctgctt cggacccaac cacacgctgt accccatggt
4501 cacgcggtgg aggcggaacg aggatggagc catctgcagg aagagcataa agaagatgct
4561 ggaagtgctg gtggtgaagc tccctctctc cgagcactgg gccctgcctg ggggctcccg
4621 ggagccaggg gagatgctac ctcggaagct gaagcggatc ctccggcagg agcactggcc
4681 gtcttttgaa aacttgctga agtgcggcat ggaggtgtac aaaggctaca tggatgaccc
4741 gaggaacacg gacaatgcct ggatcgagac ggtggccgtc agcgtccact tccaggacca
4801 gaatgacgtg gagctgaaca ggctgaactc taacctgcac gcctgcgact cgggggcctc
4861 catccgatgg caggtggtgg acaggcgcat cccactctat gcgaaccaca agaccctcct
4921 ccagaaggca gccgctgagt tcggggctca ctactgactg tgccctcagg ctgggcggct
4981 ccagtccata gacgttcccc ccagaaacca gggcttctct ctcctgagcc tggccaggac
5041 tcaggctgtt cctgggccct gcacatgatg gggtttggtg gacccagtgc ccctcacggc
5101 tgccgcaagt ctgctgcaga tgacctcatg aactggaagg ggtcaaggtg acccgggagg
5161 agagctcaag acagggcaca ggctactcag agctgagggg cccctgggac ccttggccat
5221 caggcgaggg gctgggcctg tgcagctggg cccttggcca gagtccactc ccttcctggc
5281 tgtgtcaccc cgagcagctc atccaccatg gaggtcattg gcctgaggca agttccccgg
5341 agagtcggga tcccctgtgg ccccctcagg cctatgtctg tgaggaaggg gccctgccac
5401 tctccccaag agggcctcca tgtttcgagg tgcctcaaca tggagccttg cctggcctgg
5461 gctaggggca ctgtctgaac tcctgactgt caggataaac tccgtggggg tacaggagcc
5521 cagacaaagc ccaggcctgt caagagacgc agagggcccc tgccagggtt ggccccaggg
5581 accctgggac gaggctgcag aagctctccc tccctactcc ctgggagcca cgtgctggcc
5641 atgtggccag ggacggcatg agcaggaggc ggggacgtgg gggccttctg gtttggtgtc
5701 aacagctcac aggagcgtga accatgaggg ccctcaggag gggaacgtgg taaaacccaa
5761 gacattaaat ctgccatctc aggcctggct ggctcttctg tgctttccac aaataaagtt
5821 cctgacacgt ccagggccag gggctgtgtg acggctgcct gaagttctcc tcgatccccc
5881 ggtgagcttc ctgcagcctg tggatgtcct gcagcccctc agccctaccc ccaagtttct
5941 cctctgaccc atcagctccc tgtcttcatt ttcctaaacc tgggctccag catcgtcccc
6001 aagcccacca ggccaggatg caggcatcca catgccctcc tccttggctt cccctgcgtg
6061 gtggtgccaa tgtgccctgg cacccctgca gaggctccgg atggagcctg gggctgcctg
6121 gccactgagc actggccgag gtgatgccca cccttccctg gacaggcctc tgtcttccac
6181 ctgacccaaa gctctctagc cacccccttg tccccagtat
//