LOCUS AB000409 2617 bp mRNA linear HUM 05-FEB-1999
DEFINITION Homo sapiens mRNA for MNK1, complete cds.
ACCESSION AB000409
VERSION AB000409.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2617)
AUTHORS Fukunaga,R. and Hunter,T.
TITLE Direct Submission
JOURNAL Submitted (11-JAN-1997) to the DDBJ/EMBL/GenBank databases.
Contact:Rikiro Fukunaga
Osaka University Medical School, Department of Genetics B-3; 2-2
Yamadaoka, Suita, Osaka 565-0871, Japan
REFERENCE 2
AUTHORS Fukunaga,R. and Hunter,T.
TITLE MNK1, a new MAP kinase-activated protein kinase, isolated by a
novel expression screening method for identifying protein kinase
substrates
JOURNAL EMBO J. 16, 1921-1933 (1997)
COMMENT
FEATURES Location/Qualifiers
source 1..2617
/cell_line="HeLa"
/db_xref="H-InvDB:HIT000057902"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
CDS 188..1462
/codon_start=1
/note="MAP kinase-activated protein kinase"
/product="MNK1"
/protein_id="BAA19885.1"
/transl_table=1
/translation="MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKF
EDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQ
GNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDF
LHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGS
AEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVC
RVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQ
GQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCS
MKLSPPCKSRLARRRALAQAGRGEDRSPPTAL"
regulatory 2601..2606
/regulatory_class="polyA_signal_sequence"
polyA_site 2617
/note="9 a nucleotides"
BASE COUNT 639 a 684 c 675 g 619 t
ORIGIN
1 gcgatctgca ggtaggggtg cgcgcgaccg ctccccggcg ggagccagcg aaggtttcca
61 tgtcagaggc cgatggagaa ctgaagattg ccacctacgc acaaaggcca ttgagacact
121 tcgtgtagct ggaagacacc aacttcctga caggagcttt atttcatttg ggatttcaag
181 tttacagatg gtatcttctc aaaagttgga aaaacctata gagatgggca gtagcgaacc
241 ccttcccatc gcagatggtg acaggaggag gaagaagaag cggaggggcc gggccactga
301 ctccttgcca ggaaagtttg aagatatgta caagctgacc tctgaattgc ttggagaggg
361 agcctatgcc aaagttcaag gtgccgtgag cctacagaat ggcaaagagt atgccgtcaa
421 aatcatcgag aaacaagcag ggcacagtcg gagtagggtg tttcgagagg tggagacgct
481 gtatcagtgt cagggaaaca agaacatttt ggagctgatt gagttctttg aagatgacac
541 aaggttttac ttggtctttg agaaattgca aggaggttcc atcttagccc acatccagaa
601 gcaaaagcac ttcaatgagc gagaagccag ccgagtggtg cgggacgttg ctgctgccct
661 tgacttcctg cataccaaag gcattgctca tcgtgatctg aaaccagaaa atatattgtg
721 tgaatctcca gaaaaggtgt ctccagtgaa aatctgtgac tttgacttgg gcagtgggat
781 gaaactgaac aactcctgta cccccataac cacaccagag ctgaccaccc catgtggctc
841 tgcagaatac atggcccctg aggtagtgga ggtcttcacg gaccaggcca cattctacga
901 caagcgctgt gacctgtgga gcctgggcgt ggtcctctac atcatgctga gtggctaccc
961 acccttcgtg ggtcactgcg gggccgactg tggctgggac cggggcgagg tctgcagggt
1021 gtgccagaac aagctgtttg aaagcatcca ggaaggcaag tatgagtttc ctgacaagga
1081 ctgggcacac atctccagtg aagccaaaga cctcatctcc aagctcctgg tgcgagatgc
1141 aaagcagaga cttagcgccg cccaagttct gcagcaccca tgggtgcagg ggcaagctcc
1201 agaaaaggga ctccccacgc cgcaagtcct ccagaggaac agcagcacaa tggacctgac
1261 gctcttcgca gctgaggcca tcgcccttaa ccgccagcta tctcagcacg aagagaacga
1321 actagcagag gagccagagg cactagctga tggcctctgc tccatgaagc tttcccctcc
1381 ctgcaagtca cgcctggccc ggagacgggc cctggcccag gcaggccgtg gtgaagacag
1441 gagcccgccc acagcactct gaaatgctcc agtcacacct tataggccct aggcctggcc
1501 aggcattgtc ccctggaaac ctgtgtggct aaagtctgct gagcaggcag cagcctctgc
1561 tctgtggctc cattcaggct ttttcatcta cgaaggccct gaggttccca tcaaccccca
1621 tttccctagg gtcctggagg aaaaagcttt ttccaaaggg gttgtctttg aaaaggaaag
1681 caatcacttc tcactttgca taattgcctg cagcaggaac atctcttcac tgggctccac
1741 ctgctcaccc gcctgcagat ctgggatcca gcctgctctc accgctgtag ctgtggcggc
1801 tggggctgca gcctgcaggg agaagcaaga agcatcagtt gacagaggct gccgacacgt
1861 gcctcttccc tctcttctct gtcaccctcc tctggcggtc cttccacctt cctctgtcct
1921 ccggatgtcc tctttgcccg tcttctccct tggctgagca aagccatccc ctcaattcag
1981 ggaagggcaa ggagccttcc tcattcagga aatcaaatca gtcttccggt ctgcagcacg
2041 gaaaagcaca taatctttct ttgctgtgac tgaaatgtat ccctcgttta tcatcccctt
2101 tgtttgtgat tgctgctaaa gtcagtagta tcgttttttt aaaaaaaaag tttggtgttt
2161 ttaaccatct gttccagcaa agatgatacc ttaaactccc actgcaagcc catgaacttc
2221 ccagagagtg gaacggcttg ctcttctttc tagaatgtcc atgcacttgg gttttaatca
2281 gcagttccct attattctga ttttaagctg ttcctgtgat gaacttagag acagcatcgg
2341 tgtctgctgc tgtgtcccca ggtcttgtgt gggtggcaca gatctgggca gttagatagt
2401 gctctgtgcc taaggtgaag ccacactagg gtgaagcctc acttccctgt ttgagcaatg
2461 cagtgcctgc tgcccgtgtg catgaaggta cagccattca tataagtgga actattgagt
2521 tacataaaga aaatagattt gcatttgtca ggcagacgtt tatacaacac cacggtgctt
2581 ttatacattg tgcttatttt aataaaactg aaattct
//