LOCUS X66533 2443 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens soluble guanylate cyclase small subunit mRNA.
ACCESSION X66533
VERSION X66533.1
KEYWORDS cytoplasmic protein; GTP pyrophosphate-lyase; Guanylate cyclase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Giuili G., Scholl U., Bulle F., Guellaeen G.
TITLE Molecular cloning of the cDNAs coding for the two subunits of
soluble guanylyl cyclase from human brain
JOURNAL FEBS Lett. 304(1), 83-88(1992).
PUBMED 1352257
REFERENCE 2 (bases 1 to 2443)
AUTHORS Guellaen G.
JOURNAL Submitted (10-JUL-1992) to the INSDC. Georges Guellaen, Unite
INSERM 99, Hopital Henri Mondor, 94010 Creteil, FRANCE
FEATURES Location/Qualifiers
source 1..2443
/db_xref="H-InvDB:HIT000322837"
/organism="Homo sapiens"
/chromosome="4"
/map="4q31.3-q33"
/mol_type="mRNA"
/clone_lib="lambda GT10"
/tissue_type="brain, frontal lobe"
/db_xref="taxon:9606"
CDS 89..1948
/product="guanylate cyclase"
/EC_number="4.6.1.2"
/note="soluble"
/db_xref="GOA:Q02153"
/db_xref="H-InvDB:HIT000322837.13"
/db_xref="HGNC:HGNC:4687"
/db_xref="InterPro:IPR001054"
/db_xref="InterPro:IPR011644"
/db_xref="InterPro:IPR011645"
/db_xref="InterPro:IPR018297"
/db_xref="InterPro:IPR024096"
/db_xref="InterPro:IPR029787"
/db_xref="InterPro:IPR038158"
/db_xref="InterPro:IPR042463"
/db_xref="PDB:2WZ1"
/db_xref="PDB:3UVJ"
/db_xref="PDB:4NI2"
/db_xref="PDB:5MNW"
/db_xref="UniProtKB/Swiss-Prot:Q02153"
/protein_id="CAA47144.1"
/translation="MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYD
DSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLD
ALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGT
EIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP
FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVF
VLRSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLT
RRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDT
LLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLL
NDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAG
QVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSE
YTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD"
BASE COUNT 709 a 513 c 533 g 688 t
ORIGIN
1 cccccccccg ccgctgccgc ctctgcctgg gtcccttcgg ccgtacctct gcgtgggggc
61 tgcctccccg gctcccggtg cagacaccat gtacggattt gtgaatcacg ccctggagtt
121 gctggtgatc cgcaattacg gccccgaggt gtgggaagac atcaaaaaag aggcacagtt
181 agatgaagaa ggacagtttc ttgtcagaat aatatatgat gactccaaaa cttatgattt
241 ggttgctgct gcaagcaaag tcctcaatct caatgctgga gaaatcctcc aaatgtttgg
301 gaagatgttt ttcgtctttt gccaagaatc tggttatgat acaatcttgc gtgtcctggg
361 ctctaatgtc agagaatttc tacagaacct tgatgctctg cacgaccacc ttgctaccat
421 ctacccagga atgcgtgcac cttcctttag gtgcactgat gcagaaaagg gcaaaggact
481 cattttgcac tactactcag agagagaagg acttcaggat attgtcattg gaatcatcaa
541 aacagtggca caacaaatcc atggcactga aatagacatg aaggttattc agcaaagaaa
601 tgaagaatgt gatcatactc aatttttaat tgaagaaaaa gagtcaaaag aagaggattt
661 ttatgaagat cttgacagat ttgaagaaaa tggtacccag gaatcacgca tcagcccata
721 tacattctgc aaagcttttc cttttcatat aatatttgac cgggacctag tggtcactca
781 gtgtggcaat gctatataca gagttctccc ccagctccag cctgggaatt gcagccttct
841 gtctgtcttc tcgctggttc gtcctcatat tgatattagt ttccatggga tcctttctca
901 catcaatact gtttttgtat tgagaagcaa ggaaggattg ttggatgtgg agaaattaga
961 atgtgaggat gaactgactg ggactgagat cagctgctta cgtctcaagg gtcaaatgat
1021 ctacttacct gaagcagata gcatactttt tctatgttca ccaagtgtca tgaacctgga
1081 cgatttgaca aggagagggc tgtatctaag tgacatccct ctgcatgatg ccacgcgcga
1141 tcttgttctt ttgggagaac aatttagaga ggaatacaaa ctcacccaag aactggaaat
1201 cctcactgac aggctacagc tcacgttaag agccctggaa gatgaaaaga aaaagacaga
1261 cacattgctg tattctgtcc ttcctccgtc tgttgccaat gagctgcggc acaagcgtcc
1321 agtgcctgcc aaaagatatg acaatgtgac catcctcttt agtggcattg tgggcttcaa
1381 tgctttctgt agcaagcatg catctggaga aggagccatg aagatcgtca acctcctcaa
1441 cgacctctac accagatttg acacactgac tgattcccgg aaaaacccat ttgtttataa
1501 ggtggagact gttggtgaca agtatatgac agtgagtggt ttaccagagc catgcattca
1561 ccatgcacga tccatctgcc acctggcctt ggacatgatg gaaattgctg gccaggttca
1621 agtagatggt gaatctgttc agataacaat agggatacac actggagagg tagttacagg
1681 tgtcatagga cagcggatgc ctcgatactg tctttttggg aatactgtca acctcacaag
1741 ccgaacagaa accacaggag aaaagggaaa aataaatgtg tctgaatata catacagatg
1801 tcttatgtct ccagaaaatt cagatccaca attccacttg gagcacagag gcccagtgtc
1861 catgaagggc aaaaaagaac caatgcaagt ttggtttcta tccagaaaaa atacaggaac
1921 agaggaaaca aagcaggatg atgactgaat cttggattat ggggtgaaga ggagtacaga
1981 ctaggttcca gttttctcct aacacgtgcc aagcccagga gcagttcttc cctatggata
2041 cagattttct tttgtccttg tccattaccc caagactttc ttctagatat atctctcact
2101 atccgttatt caaccttagc tctgctttct attacttttt aggctttagt atattatcta
2161 aagtttggct tttgatgtgg atgatgtgag cttcatgtgt cttaaaatct actacaagca
2221 ttacctaaca tggtgatctg caagtagtag gcacccaata aatatttgtt gaatttagtt
2281 aaatgaaact gaacagtgtt tggccatgtg tatatttata tcatgtttac caaatctgtt
2341 tagtgttcca catatatgta tatgtatatt ttaatgacta taatgtaata aagtttatat
2401 catgttggtg tatatcatta tagaaatcat tttctaaagg agt
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